FR2698367B1 - Fragments de la protéine p53 et leurs utilisations dans la détection et le suivi d'états pathologiques. - Google Patents

Fragments de la protéine p53 et leurs utilisations dans la détection et le suivi d'états pathologiques.

Info

Publication number
FR2698367B1
FR2698367B1 FR9213110A FR9213110A FR2698367B1 FR 2698367 B1 FR2698367 B1 FR 2698367B1 FR 9213110 A FR9213110 A FR 9213110A FR 9213110 A FR9213110 A FR 9213110A FR 2698367 B1 FR2698367 B1 FR 2698367B1
Authority
FR
France
Prior art keywords
fragments
protein
monitoring
detection
disease states
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9213110A
Other languages
English (en)
Other versions
FR2698367A1 (fr
Inventor
Thierry Soussi
Richard Lubin
Yann Legros
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EUROBIO LAB
Original Assignee
EUROBIO LAB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by EUROBIO LAB filed Critical EUROBIO LAB
Priority to FR9213110A priority Critical patent/FR2698367B1/fr
Priority to EP93924668A priority patent/EP0666913A1/fr
Priority to JP6510784A priority patent/JPH08502414A/ja
Priority to CA 2148274 priority patent/CA2148274A1/fr
Priority to AU54246/94A priority patent/AU5424694A/en
Priority to PCT/FR1993/001082 priority patent/WO1994010306A1/fr
Publication of FR2698367A1 publication Critical patent/FR2698367A1/fr
Application granted granted Critical
Publication of FR2698367B1 publication Critical patent/FR2698367B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4746—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used p53
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/82—Translation products from oncogenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
FR9213110A 1992-11-02 1992-11-02 Fragments de la protéine p53 et leurs utilisations dans la détection et le suivi d'états pathologiques. Expired - Fee Related FR2698367B1 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
FR9213110A FR2698367B1 (fr) 1992-11-02 1992-11-02 Fragments de la protéine p53 et leurs utilisations dans la détection et le suivi d'états pathologiques.
EP93924668A EP0666913A1 (fr) 1992-11-02 1993-11-02 FRAGMENTS DE LA PROTEINE p53 ET LEURS UTILISATIONS DANS LA DETECTION ET LE SUIVI D'ETATS PATHOLOGIQUES
JP6510784A JPH08502414A (ja) 1992-11-02 1993-11-02 ｐ５３蛋白断片とその疾患の検出およびモニタリングへの利用
CA 2148274 CA2148274A1 (fr) 1992-11-02 1993-11-02 Fragments de la proteine p53 et leurs utilisations dans la detection et le suivi d'etats pathologiques
AU54246/94A AU5424694A (en) 1992-11-02 1993-11-02 P53 protein fragments and use thereof for detecting and monitoring diseased conditions
PCT/FR1993/001082 WO1994010306A1 (fr) 1992-11-02 1993-11-02 FRAGMENTS DE LA PROTEINE p53 ET LEURS UTILISATIONS DANS LA DETECTION ET LE SUIVI D'ETATS PATHOLOGIQUES

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9213110A FR2698367B1 (fr) 1992-11-02 1992-11-02 Fragments de la protéine p53 et leurs utilisations dans la détection et le suivi d'états pathologiques.

Publications (2)

Publication Number Publication Date
FR2698367A1 FR2698367A1 (fr) 1994-05-27
FR2698367B1 true FR2698367B1 (fr) 1995-02-17

Family

ID=9435099

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9213110A Expired - Fee Related FR2698367B1 (fr) 1992-11-02 1992-11-02 Fragments de la protéine p53 et leurs utilisations dans la détection et le suivi d'états pathologiques.

Country Status (6)

Country Link
EP (1) EP0666913A1 (fr)
JP (1) JPH08502414A (fr)
AU (1) AU5424694A (fr)
CA (1) CA2148274A1 (fr)
FR (1) FR2698367B1 (fr)
WO (1) WO1994010306A1 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5770377A (en) * 1994-07-20 1998-06-23 University Of Dundee Interruption of binding of MDM2 and P53 protein and therapeutic application thereof
US5721340A (en) * 1994-11-28 1998-02-24 The Wistar Institute Of Anatomy & Biology p53 proteins with altered tetramerization domains
US5573925A (en) * 1994-11-28 1996-11-12 The Wistar Institute Of Anatomy And Biology P53 proteins with altered tetramerization domains
EP0793501A4 (fr) * 1994-12-14 2000-05-03 Scripps Research Inst Activation in vivo de lymphocytes t cytotoxiques specifiques de tumeurs
US5985829A (en) * 1994-12-19 1999-11-16 The United States Of America As Represented By The Department Of Health And Human Services Screening assays for compounds that cause apoptosis and related compounds
US6169073B1 (en) 1995-02-16 2001-01-02 Bayer Corporation Peptides and peptidomimetics with structural similarity to human p53 that activate p53 function
US5847083A (en) * 1996-08-21 1998-12-08 The Wistar Institute Of Anatomy And Biology Modified p53 constructs which enhance DNA binding
NZ334809A (en) * 1996-10-07 2000-12-22 Schering Corp Assay for the detection of antibodies against p53
AU7238098A (en) * 1997-05-15 1998-12-08 Kyowa Hakko Kogyo Co. Ltd. Peptides having cyclic structures and exerting p53 protein activty-restoring effect on p53 protein mutants
CN108780092A (zh) 2016-03-07 2018-11-09 豪夫迈·罗氏有限公司 抗p53抗体的检测

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61259337A (ja) * 1985-05-13 1986-11-17 Matsushita Electric Ind Co Ltd 電子メモ装置
EP0204922A3 (fr) * 1985-05-28 1987-09-30 Abbott Laboratories Essai immunohistochimique pour la détection d'un marqueur tumeur-associé (p53)
JPS62271122A (ja) * 1986-05-20 1987-11-25 Ricoh Co Ltd ポ−タブル型情報記録装置
JPH02219131A (ja) * 1989-02-20 1990-08-31 Toshiba Corp 表示装置
EP0390323B2 (fr) * 1989-03-29 2012-08-08 Johns Hopkins University Détection de l'écoulement du type sauvage du p53 gène
JPH02300918A (ja) * 1989-05-16 1990-12-13 Seiko Epson Corp 小型電子機器
JP3155562B2 (ja) * 1991-06-10 2001-04-09 株式会社ニチレイ 抗 体
US5411860A (en) * 1992-04-07 1995-05-02 The Johns Hopkins University Amplification of human MDM2 gene in human tumors
ES2139012T3 (es) * 1992-05-26 2000-02-01 Univ Leiden Peptidos de la proteina p53 humana destinados para ser utilizados en composiciones que inducen una reaccion en los linfocitos t humanos, y linfocitos t citotoxicos especificos de la proteina p53 humana.

Also Published As

Publication number Publication date
FR2698367A1 (fr) 1994-05-27
JPH08502414A (ja) 1996-03-19
AU5424694A (en) 1994-05-24
WO1994010306A1 (fr) 1994-05-11
CA2148274A1 (fr) 1994-05-11
EP0666913A1 (fr) 1995-08-16

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Legal Events

Date Code Title Description
ST Notification of lapse