FR2714906B1 - Agents de solubilisation de biomolécules constitués par des zwitterions non détergents et leurs utilisations. - Google Patents

Agents de solubilisation de biomolécules constitués par des zwitterions non détergents et leurs utilisations.

Info

Publication number
FR2714906B1
FR2714906B1 FR9400241A FR9400241A FR2714906B1 FR 2714906 B1 FR2714906 B1 FR 2714906B1 FR 9400241 A FR9400241 A FR 9400241A FR 9400241 A FR9400241 A FR 9400241A FR 2714906 B1 FR2714906 B1 FR 2714906B1
Authority
FR
France
Prior art keywords
biomolecules
constituted
solubilizing agents
zwitterions
detergent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9400241A
Other languages
English (en)
Other versions
FR2714906A1 (fr
Inventor
Vuillard Laurent
Rabilloud Thierry
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
VON LAUE PAUL LANGEVIN INST MA
Institut National de la Sante et de la Recherche Medicale INSERM
Commissariat a lEnergie Atomique et aux Energies Alternatives CEA
Original Assignee
VON LAUE PAUL LANGEVIN INST MA
Commissariat a lEnergie Atomique CEA
Institut National de la Sante et de la Recherche Medicale INSERM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by VON LAUE PAUL LANGEVIN INST MA, Commissariat a lEnergie Atomique CEA, Institut National de la Sante et de la Recherche Medicale INSERM filed Critical VON LAUE PAUL LANGEVIN INST MA
Priority to FR9400241A priority Critical patent/FR2714906B1/fr
Priority to EP95907027A priority patent/EP0739334A1/fr
Priority to JP7518875A priority patent/JPH09511735A/ja
Priority to ES95907027T priority patent/ES2099052T1/es
Priority to DE0739334T priority patent/DE739334T1/de
Priority to PCT/FR1995/000035 priority patent/WO1995019339A1/fr
Publication of FR2714906A1 publication Critical patent/FR2714906A1/fr
Application granted granted Critical
Publication of FR2714906B1 publication Critical patent/FR2714906B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
    • C07D213/16—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing only one pyridine ring
    • C07D213/20—Quaternary compounds thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01—Sulfonic acids
    • C07C309/02—Sulfonic acids having sulfo groups bound to acyclic carbon atoms
    • C07C309/03—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C309/13—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton
    • C07C309/14—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton containing amino groups bound to the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/24—Extraction; Separation; Purification by electrochemical means
    • C07K1/26—Electrophoresis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
FR9400241A 1994-01-12 1994-01-12 Agents de solubilisation de biomolécules constitués par des zwitterions non détergents et leurs utilisations. Expired - Fee Related FR2714906B1 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
FR9400241A FR2714906B1 (fr) 1994-01-12 1994-01-12 Agents de solubilisation de biomolécules constitués par des zwitterions non détergents et leurs utilisations.
EP95907027A EP0739334A1 (fr) 1994-01-12 1995-01-11 Agents de solubilisation de biomolecules constitues par des zwitterions non detergents et leurs utilisations
JP7518875A JPH09511735A (ja) 1994-01-12 1995-01-11 非洗浄性双性イオンからなる生物分子溶解剤およびその使用
ES95907027T ES2099052T1 (es) 1994-01-12 1995-01-11 Agentes de solubilizacion de biomoleculas constituidos por iones hibridos no detergentes y su utilizacion.
DE0739334T DE739334T1 (de) 1994-01-12 1995-01-11 Solubilisierungsmittel für biomoleküle, bestehend aus nicht-tensidischen zwitterionen und ihre verwendung
PCT/FR1995/000035 WO1995019339A1 (fr) 1994-01-12 1995-01-11 Agents de solubilisation de biomolecules constitues par des zwitterions non detergents et leurs utilisations

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9400241A FR2714906B1 (fr) 1994-01-12 1994-01-12 Agents de solubilisation de biomolécules constitués par des zwitterions non détergents et leurs utilisations.

Publications (2)

Publication Number Publication Date
FR2714906A1 FR2714906A1 (fr) 1995-07-13
FR2714906B1 true FR2714906B1 (fr) 1996-02-02

Family

ID=9458941

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9400241A Expired - Fee Related FR2714906B1 (fr) 1994-01-12 1994-01-12 Agents de solubilisation de biomolécules constitués par des zwitterions non détergents et leurs utilisations.

Country Status (6)

Country Link
EP (1) EP0739334A1 (fr)
JP (1) JPH09511735A (fr)
DE (1) DE739334T1 (fr)
ES (1) ES2099052T1 (fr)
FR (1) FR2714906B1 (fr)
WO (1) WO1995019339A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPO403496A0 (en) * 1996-12-05 1997-01-02 Macquarie Research Limited Electrophoresis separation methods
US20020052026A1 (en) 1997-10-08 2002-05-02 Steven M. Vicik Methods of refolding proteins

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4372888A (en) * 1980-08-26 1983-02-08 The United States Of America As Represented By The Secretary Of The Department Of Health & Human Services Nondenaturing zwitterionic detergents
EP0141879A1 (fr) * 1983-10-18 1985-05-22 Victor A. Bernstam Compositions surfactantes et méthodes pour la clarification et le partage de spécimens aqueux contenant des lipides
CA2048302A1 (fr) * 1990-08-15 1992-02-16 Victoria P. Meucci Reactif de solubilisation des echantillons dans des epreuves biologiques
JPH0557114A (ja) * 1991-01-11 1993-03-09 Millipore Corp 高効率の毛管電気泳動分離法

Also Published As

Publication number Publication date
WO1995019339A1 (fr) 1995-07-20
DE739334T1 (de) 1997-06-05
FR2714906A1 (fr) 1995-07-13
JPH09511735A (ja) 1997-11-25
EP0739334A1 (fr) 1996-10-30
ES2099052T1 (es) 1997-05-16

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Legal Events

Date Code Title Description
TP Transmission of property
ST Notification of lapse