FR2803599B1 - Nouveau virus mute de l'hepatite b, ses constituants nucleiques et proteiques et leurs applications - Google Patents

Nouveau virus mute de l'hepatite b, ses constituants nucleiques et proteiques et leurs applications

Info

Publication number
FR2803599B1
FR2803599B1 FR0000129A FR0000129A FR2803599B1 FR 2803599 B1 FR2803599 B1 FR 2803599B1 FR 0000129 A FR0000129 A FR 0000129A FR 0000129 A FR0000129 A FR 0000129A FR 2803599 B1 FR2803599 B1 FR 2803599B1
Authority
FR
France
Prior art keywords
virus
nucleic
applications
protein constituents
new mutated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0000129A
Other languages
English (en)
Other versions
FR2803599A1 (fr
Inventor
Christian Trepo
Bernard Mandrand
Alan Kay
Isabelle Chemin
Pradel Florence Komurian
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut National de la Sante et de la Recherche Medicale INSERM
Original Assignee
Institut National de la Sante et de la Recherche Medicale INSERM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0000129A priority Critical patent/FR2803599B1/fr
Application filed by Institut National de la Sante et de la Recherche Medicale INSERM filed Critical Institut National de la Sante et de la Recherche Medicale INSERM
Priority to AU31847/01A priority patent/AU3184701A/en
Priority to BR0107457-1A priority patent/BR0107457A/pt
Priority to US10/169,668 priority patent/US20030129202A1/en
Priority to EP01903881A priority patent/EP1244773A1/fr
Priority to JP2001550357A priority patent/JP2003519477A/ja
Priority to PCT/FR2001/000038 priority patent/WO2001049828A1/fr
Publication of FR2803599A1 publication Critical patent/FR2803599A1/fr
Application granted granted Critical
Publication of FR2803599B1 publication Critical patent/FR2803599B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • General Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR0000129A 2000-01-06 2000-01-06 Nouveau virus mute de l'hepatite b, ses constituants nucleiques et proteiques et leurs applications Expired - Fee Related FR2803599B1 (fr)

Priority Applications (7)

Application Number Priority Date Filing Date Title
FR0000129A FR2803599B1 (fr) 2000-01-06 2000-01-06 Nouveau virus mute de l'hepatite b, ses constituants nucleiques et proteiques et leurs applications
BR0107457-1A BR0107457A (pt) 2000-01-06 2001-01-05 Vìrus de hepatite b com mutação, seus constituintes nuclêico e de proteìna, e usos destes
US10/169,668 US20030129202A1 (en) 2000-01-06 2001-01-05 Mutated hepatitis b virus, its nucleic and protein constituents and uses thereof
EP01903881A EP1244773A1 (fr) 2000-01-06 2001-01-05 Virus mute de l'hepatite b, ses constinuants nucleiques et proteiques et leurs applications
AU31847/01A AU3184701A (en) 2000-01-06 2001-01-05 Mutated hepatitis B virus, its nucleic and protein constituents and uses thereof
JP2001550357A JP2003519477A (ja) 2000-01-06 2001-01-05 突然変異ｂ型肝炎ウイルス、その核およびタンパク質の構成成分およびその使用
PCT/FR2001/000038 WO2001049828A1 (fr) 2000-01-06 2001-01-05 Virus mute de l'hepatite b, ses constituants nucleiques et proteiques et leurs applications

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0000129A FR2803599B1 (fr) 2000-01-06 2000-01-06 Nouveau virus mute de l'hepatite b, ses constituants nucleiques et proteiques et leurs applications

Publications (2)

Publication Number Publication Date
FR2803599A1 FR2803599A1 (fr) 2001-07-13
FR2803599B1 true FR2803599B1 (fr) 2004-11-19

Family

ID=8845662

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0000129A Expired - Fee Related FR2803599B1 (fr) 2000-01-06 2000-01-06 Nouveau virus mute de l'hepatite b, ses constituants nucleiques et proteiques et leurs applications

Country Status (7)

Country Link
US (1) US20030129202A1 (fr)
EP (1) EP1244773A1 (fr)
JP (1) JP2003519477A (fr)
AU (1) AU3184701A (fr)
BR (1) BR0107457A (fr)
FR (1) FR2803599B1 (fr)
WO (1) WO2001049828A1 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7309589B2 (en) * 2004-08-20 2007-12-18 Vironix Llc Sensitive detection of bacteria by improved nested polymerase chain reaction targeting the 16S ribosomal RNA gene and identification of bacterial species by amplicon sequencing
EP1696040A1 (fr) * 2005-02-28 2006-08-30 Eurofins Viralliance, Inc. Procédé de détection du genotype et du phenotype d'hépatite B résitant aux molécules antiviraux
BR112012002628B1 (pt) * 2009-08-07 2021-09-08 Transgene Sa Composição imunogênica, molécula de ácido nucleico, vetor, partícula viral infecciosa, micro-organismo transgênico, composição, usos da composição imunogênica e kit de partes
CN108779472B (zh) * 2015-11-04 2022-09-09 霍欧奇帕生物科技有限公司 针对乙型肝炎病毒的疫苗
EP3373959B1 (fr) 2015-11-12 2022-06-29 Hookipa Biotech GmbH Particules d'arenavirus en tant que vaccins contre le cancer
CN108659107A (zh) * 2018-05-23 2018-10-16 基蛋生物科技股份有限公司 一种HBcAg的表达纯化方法
US12331320B2 (en) 2018-10-10 2025-06-17 The Research Foundation For The State University Of New York Genome edited cancer cell vaccines
CN116479182B (zh) * 2023-05-05 2024-01-30 赛立安生物技术(广州)有限公司 一种用于检测hbv前c区及核心启动子区突变的引物组、检测方法及其试剂盒

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0414374B1 (fr) * 1989-07-25 1997-10-08 Smithkline Biologicals S.A. Antigènes ainsi que les méthodes pour leur préparation
JPH06503231A (ja) * 1991-09-18 1994-04-14 アムジエン・インコーポレーテツド 胆汁酸塩を含有するｂ型肝炎ワクチン製剤
US5376525A (en) * 1992-09-24 1994-12-27 The United States Of America As Represented By The Department Of Health And Human Services Method for detection of mycoplasma
AU5679394A (en) * 1992-11-25 1994-06-22 International Biotechnology Laboratories, Inc. Hepatitis b virus vaccines
GB9401987D0 (en) * 1994-02-02 1994-03-30 Imperial College Modified nucleic acid

Also Published As

Publication number Publication date
JP2003519477A (ja) 2003-06-24
US20030129202A1 (en) 2003-07-10
AU3184701A (en) 2001-07-16
EP1244773A1 (fr) 2002-10-02
FR2803599A1 (fr) 2001-07-13
WO2001049828A1 (fr) 2001-07-12
BR0107457A (pt) 2003-02-11

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Effective date: 20081029