FR3110582B1 - Biomatériau comprenant au moins une matrice élastomère et un polysaccharide non sulfaté et ses utilisations. - Google Patents

Biomatériau comprenant au moins une matrice élastomère et un polysaccharide non sulfaté et ses utilisations. Download PDF

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Publication number
FR3110582B1
FR3110582B1 FR2005382A FR2005382A FR3110582B1 FR 3110582 B1 FR3110582 B1 FR 3110582B1 FR 2005382 A FR2005382 A FR 2005382A FR 2005382 A FR2005382 A FR 2005382A FR 3110582 B1 FR3110582 B1 FR 3110582B1
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FR
France
Prior art keywords
biomaterial
elastomeric matrix
sulphated polysaccharide
polysaccharide
reconstruction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR2005382A
Other languages
English (en)
Other versions
FR3110582A1 (fr
Inventor
Didier Lutomski
Géraldine Rohman
Sylvie Changotade
Karim Senni
Carole Chakar
Wassim Manhal
Ronald Younes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universite St Joseph De Beyrouth Lb
Centre National de la Recherche Scientifique CNRS
Universite Sorbonne Paris Nord
Universite Paris Cite
Original Assignee
Centre National de la Recherche Scientifique CNRS
Universite Sorbonne Paris Nord
Universite de Paris
Univ St Joseph De Beyrouth
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre National de la Recherche Scientifique CNRS, Universite Sorbonne Paris Nord, Universite de Paris, Univ St Joseph De Beyrouth filed Critical Centre National de la Recherche Scientifique CNRS
Priority to FR2005382A priority Critical patent/FR3110582B1/fr
Priority to JP2022571177A priority patent/JP7802692B2/ja
Priority to EP21726418.3A priority patent/EP4153651A1/fr
Priority to PCT/EP2021/063472 priority patent/WO2021234088A1/fr
Priority to US17/997,433 priority patent/US20230263937A1/en
Priority to CN202080101135.0A priority patent/CN115803356B/zh
Publication of FR3110582A1 publication Critical patent/FR3110582A1/fr
Application granted granted Critical
Publication of FR3110582B1 publication Critical patent/FR3110582B1/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/26Mixtures of macromolecular compounds
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00Polymeric products of isocyanates or isothiocyanates
    • C08G18/06Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/70Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the isocyanates or isothiocyanates used
    • C08G18/72Polyisocyanates or polyisothiocyanates
    • C08G18/73Polyisocyanates or polyisothiocyanates acyclic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728Hyaluronic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56Porous materials, e.g. foams or sponges
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00Polymeric products of isocyanates or isothiocyanates
    • C08G18/06Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/08Processes
    • C08G18/16Catalysts
    • C08G18/22Catalysts containing metal compounds
    • C08G18/24Catalysts containing metal compounds of tin
    • C08G18/244Catalysts containing metal compounds of tin tin salts of carboxylic acids
    • C08G18/246Catalysts containing metal compounds of tin tin salts of carboxylic acids containing also tin-carbon bonds
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00Polymeric products of isocyanates or isothiocyanates
    • C08G18/06Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40High-molecular-weight compounds
    • C08G18/42Polycondensates having carboxylic or carbonic ester groups in the main chain
    • C08G18/4266Polycondensates having carboxylic or carbonic ester groups in the main chain prepared from hydroxycarboxylic acids and/or lactones
    • C08G18/4269Lactones
    • C08G18/4277Caprolactone and/or substituted caprolactone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/23Carbohydrates
    • A61L2300/236Glycosaminoglycans, e.g. heparin, hyaluronic acid, chondroitin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/12Materials or treatment for tissue regeneration for dental implants or prostheses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/34Materials or treatment for tissue regeneration for soft tissue reconstruction

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Dermatology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Materials For Medical Uses (AREA)

Abstract

« Biomatériau comprenant au moins une matrice élastomère et un polysaccharide non sulfaté et ses utilisations. » La présente invention concerne un biomatériau comprenant au moins une matrice élastomère et un polysaccharide, et ses utilisations dans le renforcement, la reconstruction et/ou du comblement des défauts tissulaires, de préférence le renforcement, la reconstruction et/ou du comblement des défauts des tissus mous et/ou les tissus épithéliaux, de préférence la réparation de la peau et/ou des muqueuses.
FR2005382A 2020-05-20 2020-05-20 Biomatériau comprenant au moins une matrice élastomère et un polysaccharide non sulfaté et ses utilisations. Active FR3110582B1 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
FR2005382A FR3110582B1 (fr) 2020-05-20 2020-05-20 Biomatériau comprenant au moins une matrice élastomère et un polysaccharide non sulfaté et ses utilisations.
JP2022571177A JP7802692B2 (ja) 2020-05-20 2021-05-20 少なくとも1つのエラストマーマトリックスおよび非硫酸化多糖を含む生体材料およびその使用
EP21726418.3A EP4153651A1 (fr) 2020-05-20 2021-05-20 Biomateriau comprenant au moins une matrice elastomere et un polysaccharide non sulfate et ses utilisations
PCT/EP2021/063472 WO2021234088A1 (fr) 2020-05-20 2021-05-20 Biomateriau comprenant au moins une matrice elastomere et un polysaccharide non sulfate et ses utilisations
US17/997,433 US20230263937A1 (en) 2020-05-20 2021-05-20 Biomaterial comprising at least one elastomeric matrix and a non-sulfated polysaccharide and uses thereof
CN202080101135.0A CN115803356B (zh) 2020-05-20 2021-05-20 包括至少一种弹性体基质和非硫酸化多糖的生物材料及其用途

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR2005382 2020-05-20
FR2005382A FR3110582B1 (fr) 2020-05-20 2020-05-20 Biomatériau comprenant au moins une matrice élastomère et un polysaccharide non sulfaté et ses utilisations.

Publications (2)

Publication Number Publication Date
FR3110582A1 FR3110582A1 (fr) 2021-11-26
FR3110582B1 true FR3110582B1 (fr) 2023-04-14

Family

ID=72178756

Family Applications (1)

Application Number Title Priority Date Filing Date
FR2005382A Active FR3110582B1 (fr) 2020-05-20 2020-05-20 Biomatériau comprenant au moins une matrice élastomère et un polysaccharide non sulfaté et ses utilisations.

Country Status (6)

Country Link
US (1) US20230263937A1 (fr)
EP (1) EP4153651A1 (fr)
JP (1) JP7802692B2 (fr)
CN (1) CN115803356B (fr)
FR (1) FR3110582B1 (fr)
WO (1) WO2021234088A1 (fr)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130295081A1 (en) * 2008-10-30 2013-11-07 Vanderbilt University Polyurethane Composite for Wound Healing and Methods Thereof
US9050176B2 (en) * 2009-04-03 2015-06-09 Biomerix Corporation At least partially resorbable reticulated elastomeric matrix elements and methods of making same
WO2011075183A1 (fr) * 2009-12-15 2011-06-23 Vanderbilt University Composites tissu-polyuréthane injectables/se formant in situ et procédés de préparation associés
US10772992B2 (en) * 2016-02-17 2020-09-15 The Governing Council Of The University Of Toronto Soft tissue filler
CN108034225B (zh) * 2017-12-25 2020-07-10 武汉市工程科学技术研究院 一种制备壳聚糖/热塑性聚氨酯弹性体复合材料的方法

Also Published As

Publication number Publication date
JP2023526504A (ja) 2023-06-21
WO2021234088A1 (fr) 2021-11-25
FR3110582A1 (fr) 2021-11-26
EP4153651A1 (fr) 2023-03-29
JP7802692B2 (ja) 2026-01-20
US20230263937A1 (en) 2023-08-24
CN115803356A (zh) 2023-03-14
CN115803356B (zh) 2026-03-27

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