GB2142623B - 3-(3-hydroxybutoxy)-1-butanol and its method of preparation - Google Patents

3-(3-hydroxybutoxy)-1-butanol and its method of preparation

Info

Publication number
GB2142623B
GB2142623B GB08411356A GB8411356A GB2142623B GB 2142623 B GB2142623 B GB 2142623B GB 08411356 A GB08411356 A GB 08411356A GB 8411356 A GB8411356 A GB 8411356A GB 2142623 B GB2142623 B GB 2142623B
Authority
GB
United Kingdom
Prior art keywords
hydroxybutoxy
butanol
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB08411356A
Other languages
English (en)
Other versions
GB2142623A (en
GB8411356D0 (en
Inventor
Elso Manghisi
Aldo Salimbeni
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Istituto Luso Farmaco dItalia SpA
Original Assignee
Istituto Luso Farmaco dItalia SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Istituto Luso Farmaco dItalia SpA filed Critical Istituto Luso Farmaco dItalia SpA
Publication of GB8411356D0 publication Critical patent/GB8411356D0/en
Publication of GB2142623A publication Critical patent/GB2142623A/en
Application granted granted Critical
Publication of GB2142623B publication Critical patent/GB2142623B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/04—Saturated ethers
    • C07C43/13—Saturated ethers containing hydroxy or O-metal groups
    • C07C43/132—Saturated ethers containing hydroxy or O-metal groups both carbon chains being substituted by hydroxy or O-metal groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/14—Unsaturated ethers
    • C07C43/164—Unsaturated ethers containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/14—Unsaturated ethers
    • C07C43/178—Unsaturated ethers containing hydroxy or O-metal groups
    • C07C43/1785—Unsaturated ethers containing hydroxy or O-metal groups having more than one ether bound

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB08411356A 1983-05-30 1984-05-03 3-(3-hydroxybutoxy)-1-butanol and its method of preparation Expired GB2142623B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT21352/83A IT1164254B (it) 1983-05-30 1983-05-30 3-(3-idrossibutossi)-1-butanolo e suo metodo di preparazione

Publications (3)

Publication Number Publication Date
GB8411356D0 GB8411356D0 (en) 1984-06-06
GB2142623A GB2142623A (en) 1985-01-23
GB2142623B true GB2142623B (en) 1987-04-15

Family

ID=11180528

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08411356A Expired GB2142623B (en) 1983-05-30 1984-05-03 3-(3-hydroxybutoxy)-1-butanol and its method of preparation

Country Status (8)

Country Link
US (1) US4584321A (2)
JP (1) JPS604146A (2)
BE (1) BE899790A (2)
DE (1) DE3419947A1 (2)
ES (1) ES8507449A1 (2)
FR (1) FR2547813B1 (2)
GB (1) GB2142623B (2)
IT (1) IT1164254B (2)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL145712A0 (en) 1999-04-01 2002-07-25 Esperion Therapeutics Inc Ether compounds, compositions, and uses thereof
US6713507B2 (en) 2000-10-11 2004-03-30 Esperion Therapeutics, Inc. Ether compounds and compositions for cholesterol management and related uses
US20040122091A1 (en) * 2000-10-11 2004-06-24 Esperion Therapeutics, Inc. Sulfoxide and bis-sulfoxide compounds and compositions for cholesterol management and related uses
AU2002211666A1 (en) 2000-10-11 2002-04-22 Esperion Therapeutics, Inc. Sulfide and disulfide compounds and compositions for cholesterol management and related uses
IL155246A0 (en) 2000-10-11 2003-11-23 Esperion Therapeutics Inc Sulfoxide and bis-sulfoxide compounds and compositions for cholesterol management and related uses
CA2425311C (en) 2000-10-11 2011-06-14 Esperion Therapeutics, Inc. Ketone compounds and compositions for cholesterol management and related uses
US7304093B2 (en) * 2000-10-11 2007-12-04 Esperion Therapeutics, Inc. Ketone compounds and compositions for cholesterol management and related uses
US20040204502A1 (en) * 2001-10-11 2004-10-14 Dasseux Jean-Louis Henri Sulfoxide and bis-sulfoxide compounds and compositions for cholesterol management and related uses
US20050020694A1 (en) * 2001-10-11 2005-01-27 Dasseux Jean-Louis Henri Sulfide and disulfide compounds and compositions for cholesterol management and related uses
US20040192771A1 (en) * 2001-10-11 2004-09-30 Dasseux Jean-Louis Henri Ether compounds and compositions for cholesterol management and related uses
EP1495034A2 (en) * 2002-04-10 2005-01-12 Esperion Therapeutics, Inc. Mimics of acyl coenzyme-a comprising pantolactone and pantothenic acid derivatives, compositions thereof, and methods of cholesterol management and related uses
CA2513660C (en) * 2003-01-23 2012-05-08 Esperion Therapeutics, Inc. Hydroxyl compounds and compositions for cholesterol management and related uses
WO2005068412A1 (en) 2003-12-24 2005-07-28 Esperion Therapeutics, Inc. Ketone compounds and compositions for cholesterol management and related uses
CN103848726B (zh) * 2012-12-09 2017-09-05 河北凯盛医药科技有限公司 一种高纯度二羟二丁基醚及其制备方法
CN103304383B (zh) * 2013-06-18 2015-04-08 重庆医科大学 保胆健素的新合成方法
CN103319316B (zh) * 2013-06-24 2015-06-10 大连理工大学 一种二羟基二丁醚的绿色制备方法
CN103333057A (zh) * 2013-06-24 2013-10-02 大连理工大学 一种二羟基二丁醚的制备方法
CN104230674A (zh) * 2014-08-28 2014-12-24 成都邦泽生物医药科技有限公司 一种二羟基二丁醚的制备方法
CN107530307A (zh) 2015-03-13 2018-01-02 艾斯柏伦治疗公司 包含etc1002和依泽替米贝的固定剂量组合和制剂以及治疗心血管疾病或降低心血管疾病风险的方法
MA41793A (fr) 2015-03-16 2018-01-23 Esperion Therapeutics Inc Associations de doses fixes comprenant du etc1002 et une ou plusieurs statines permettant de traiter ou de réduire un risque cardiovasculaire
EP4438114A3 (en) 2019-06-21 2024-12-25 Esperion Therapeutics, Inc. Methods of making bempedoic acid and compositions of the same

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT957008B (it) * 1967-11-09 1973-10-10 Luso Farmaco Inst Processo per la preparazione di eteri simmetrici di glicoli re canti ossidrili primari e secon dari
DE2218935C3 (de) * 1972-04-19 1980-01-31 Basf Ag, 6700 Ludwigshafen Verfahren zur Herstellung von wäßrigen Lösungen von N-Vinylpyrrolidonpolymerisaten

Also Published As

Publication number Publication date
GB2142623A (en) 1985-01-23
US4584321A (en) 1986-04-22
FR2547813A1 (fr) 1984-12-28
ES532802A0 (es) 1985-10-01
BE899790A (fr) 1984-11-30
JPS6241702B2 (2) 1987-09-04
GB8411356D0 (en) 1984-06-06
FR2547813B1 (fr) 1989-01-27
IT1164254B (it) 1987-04-08
DE3419947C2 (2) 1987-11-26
DE3419947A1 (de) 1984-12-06
IT8321352A1 (it) 1984-11-30
IT8321352A0 (it) 1983-05-30
JPS604146A (ja) 1985-01-10
ES8507449A1 (es) 1985-10-01

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Legal Events

Date Code Title Description
PE20 Patent expired after termination of 20 years

Effective date: 20040502