GC0000155A - 6-Hydroxy-indazole derivatives for treating glaucoma. - Google Patents

6-Hydroxy-indazole derivatives for treating glaucoma.

Info

Publication number
GC0000155A
GC0000155A GCP20001082A GC0000155A GC 0000155 A GC0000155 A GC 0000155A GC P20001082 A GCP20001082 A GC P20001082A GC 0000155 A GC0000155 A GC 0000155A
Authority
GC
Cooperation Council for the Arab states of the Gulf
Prior art keywords
hydroxy
treating glaucoma
indazole derivatives
indazole
derivatives
Prior art date
Application number
Inventor
Jesse A May
Zixia Feng
Anura Dantanarayana
Original Assignee
Alcon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Inc filed Critical Alcon Inc
Application granted granted Critical
Publication of GC0000155A publication Critical patent/GC0000155A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GCP20001082 2000-03-17 2000-12-03 6-Hydroxy-indazole derivatives for treating glaucoma. GC0000155A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US19038000P 2000-03-17 2000-03-17

Publications (1)

Publication Number Publication Date
GC0000155A true GC0000155A (en) 2005-06-29

Family

ID=22701093

Family Applications (1)

Application Number Title Priority Date Filing Date
GCP20001082 GC0000155A (en) 2000-03-17 2000-12-03 6-Hydroxy-indazole derivatives for treating glaucoma.

Country Status (14)

Country Link
EP (1) EP1268438A1 (en)
JP (1) JP2003528085A (en)
KR (1) KR20030065304A (en)
CN (1) CN1450994A (en)
AR (1) AR032138A1 (en)
AU (1) AU2001216072A1 (en)
BR (1) BR0017157A (en)
CA (1) CA2402403A1 (en)
GC (1) GC0000155A (en)
MX (1) MXPA02008547A (en)
PL (1) PL358481A1 (en)
TW (1) TWI221839B (en)
WO (1) WO2001070702A1 (en)
ZA (1) ZA200206851B (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6960579B1 (en) 1998-05-19 2005-11-01 Alcon Manufacturing, Ltd. Serotonergic 5HT7 receptor compounds for treating ocular and CNS disorders
TW593302B (en) 2001-12-20 2004-06-21 Alcon Inc Novel benzodifuranimidazoline and benzofuranimidazoline derivatives and their use for the treatment of glaucoma
WO2003057213A2 (en) * 2001-12-28 2003-07-17 Bayer Pharmaceuticals Corporation Cyclohexano- and cycloheptapyrazole derivative compounds, for use in diseases associated with the 5-ht2c receptor
US7196082B2 (en) * 2002-11-08 2007-03-27 Merck & Co. Inc. Ophthalmic compositions for treating ocular hypertension
CN100384827C (en) * 2002-11-08 2008-04-30 默克公司 Ophthalmic composition for the treatment of ocular hypertension
EP1581503A4 (en) 2002-11-08 2007-07-25 Merck & Co Inc OPHTHALMIC COMPOSITIONS FOR TREATING OCULAR HYPERTENSION
US7053085B2 (en) 2003-03-26 2006-05-30 Merck & Co. Inc. EP4 receptor agonist, compositions and methods thereof
BR0316775A (en) 2002-12-13 2005-11-01 Alcon Inc New benzopyran analogues and their use for treating glaucoma
JP2004262812A (en) * 2003-02-28 2004-09-24 Rohto Pharmaceut Co Ltd Ocular hypotensive
AU2004268012B2 (en) 2003-09-02 2008-11-20 Merck & Co., Inc. Ophthalmic compositions for treating ocular hypertension
BRPI0414102A (en) 2003-09-04 2006-10-31 Merck & Co Inc compound use and composition
US7494983B2 (en) 2003-09-04 2009-02-24 Merck & Co. Inc. Ophthalmic compositions for treating ocular hypertension
US7338972B1 (en) 2003-12-15 2008-03-04 Alcon, Inc. Substituted 1-alkylamino-1H-indazoles for the treatment of glaucoma
AR046890A1 (en) 2003-12-15 2005-12-28 Alcon Inc [1,4] OXAZINO [2,3-G] SUBSTITUTED INDAZOLS FOR THE TREATMENT OF GLAUCOMA.
US7129257B1 (en) 2003-12-15 2006-10-31 Alcon, Inc. Pyrazolo[3,4- e]benzoxazoles for the treatment of glaucoma
US7563816B2 (en) 2004-07-20 2009-07-21 Merck & Co. Inc. Ophthalmic compositions for treating ocular hypertension
EA012245B1 (en) 2004-11-29 2009-08-28 УОРНЕР-ЛАМБЕРТ КОМПАНИ Эд-Эл-Си Therapeutic pyrazolo[3,4-b] pyridines and indazoles
WO2006062839A1 (en) 2004-12-08 2006-06-15 Alcon, Inc. Use of dioxindoindazoles and dioxoloindazoles for treating glaucoma
CN101704785B (en) * 2009-11-16 2012-02-29 东南大学 Organic dicarboxylic acid and salts thereof and preparation method thereof
CN105884687B (en) * 2016-04-14 2018-06-22 梯尔希（南京）药物研发有限公司 A kind of preparation method of 5- benzyls benzydamine

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9910590A (en) * 1998-05-19 2001-01-23 Alcon Lab Inc Compound, process to decrease iop, to improve blood flow to the end of the optic nerve and the retina, and to treat retinal diseases, compositions to decrease iop, to improve blood flow to the end of the optic nerve and the retina, and to treating retinal diseases, process and composition to provide neuroprotection to the end of the optic nerve or the retina, and, process to treat people suffering from sleep disorders, depression, schizophrenia, anxiety, circadian rhythmic disorders and centrally and peripherally mediated hypertension
DE69910706T2 (en) * 1998-05-26 2004-07-08 Pfizer Products Inc., Groton Drug used to treat glaucoma and ischemic retinopathy
GB9819032D0 (en) * 1998-09-01 1998-10-28 Cerebrus Ltd Chemical compounds IV
AU755119B2 (en) * 1998-09-18 2002-12-05 Alcon Laboratories, Inc. Serotonergic 5HT2 agonists for treating glaucoma
GB9820767D0 (en) * 1998-09-23 1998-11-18 Cerebrus Ltd Chemical compounds VIII

Also Published As

Publication number Publication date
WO2001070702A1 (en) 2001-09-27
KR20030065304A (en) 2003-08-06
AR032138A1 (en) 2003-10-29
JP2003528085A (en) 2003-09-24
ZA200206851B (en) 2003-10-21
AU2001216072A1 (en) 2001-10-03
MXPA02008547A (en) 2003-03-12
TWI221839B (en) 2004-10-11
BR0017157A (en) 2002-11-26
EP1268438A1 (en) 2003-01-02
CA2402403A1 (en) 2001-09-27
PL358481A1 (en) 2004-08-09
CN1450994A (en) 2003-10-22

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