PL358481A1 - 6-hydroxy-indazole derivatives for treating glaucoma - Google Patents
6-hydroxy-indazole derivatives for treating glaucomaInfo
- Publication number
- PL358481A1 PL358481A1 PL00358481A PL35848100A PL358481A1 PL 358481 A1 PL358481 A1 PL 358481A1 PL 00358481 A PL00358481 A PL 00358481A PL 35848100 A PL35848100 A PL 35848100A PL 358481 A1 PL358481 A1 PL 358481A1
- Authority
- PL
- Poland
- Prior art keywords
- hydroxy
- treating glaucoma
- indazole derivatives
- indazole
- derivatives
- Prior art date
Links
- NUYZVDBIVNOTSC-UHFFFAOYSA-N 1H-indazol-6-ol Chemical class OC1=CC=C2C=NNC2=C1 NUYZVDBIVNOTSC-UHFFFAOYSA-N 0.000 title 1
- 208000010412 Glaucoma Diseases 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19038000P | 2000-03-17 | 2000-03-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL358481A1 true PL358481A1 (en) | 2004-08-09 |
Family
ID=22701093
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL00358481A PL358481A1 (en) | 2000-03-17 | 2000-11-14 | 6-hydroxy-indazole derivatives for treating glaucoma |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP1268438A1 (en) |
| JP (1) | JP2003528085A (en) |
| KR (1) | KR20030065304A (en) |
| CN (1) | CN1450994A (en) |
| AR (1) | AR032138A1 (en) |
| AU (1) | AU2001216072A1 (en) |
| BR (1) | BR0017157A (en) |
| CA (1) | CA2402403A1 (en) |
| GC (1) | GC0000155A (en) |
| MX (1) | MXPA02008547A (en) |
| PL (1) | PL358481A1 (en) |
| TW (1) | TWI221839B (en) |
| WO (1) | WO2001070702A1 (en) |
| ZA (1) | ZA200206851B (en) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6960579B1 (en) | 1998-05-19 | 2005-11-01 | Alcon Manufacturing, Ltd. | Serotonergic 5HT7 receptor compounds for treating ocular and CNS disorders |
| TW593302B (en) | 2001-12-20 | 2004-06-21 | Alcon Inc | Novel benzodifuranimidazoline and benzofuranimidazoline derivatives and their use for the treatment of glaucoma |
| AU2002360819A1 (en) * | 2001-12-28 | 2003-07-24 | Bayer Corporation | Cyclohexano- and cycloheptapyrazole derivative compounds, for use in diseases associated with the 5-ht2c receptor |
| US7196082B2 (en) | 2002-11-08 | 2007-03-27 | Merck & Co. Inc. | Ophthalmic compositions for treating ocular hypertension |
| CN100384827C (en) * | 2002-11-08 | 2008-04-30 | 默克公司 | Ophthalmic composition for the treatment of ocular hypertension |
| WO2004043354A2 (en) | 2002-11-08 | 2004-05-27 | Merck & Co., Inc. | Ophthalmic compositions for treating ocular hypertension |
| US7053085B2 (en) | 2003-03-26 | 2006-05-30 | Merck & Co. Inc. | EP4 receptor agonist, compositions and methods thereof |
| EP1581209A4 (en) | 2002-12-13 | 2009-03-11 | Alcon Inc | Novel benzopyran analogs and their use for the treatment of glaucoma |
| JP2004262812A (en) * | 2003-02-28 | 2004-09-24 | Rohto Pharmaceut Co Ltd | Ocular hypotensive |
| CN1845914A (en) | 2003-09-02 | 2006-10-11 | 默克公司 | Ophthalmic compositions for treating ocular hypertension |
| AU2004272546B2 (en) | 2003-09-04 | 2007-10-18 | Merck Sharp & Dohme Corp. | Ophthalmic compositions for treating ocular hypertension |
| AU2004271978B2 (en) | 2003-09-04 | 2009-02-05 | Merck & Co., Inc. | Ophthalmic compositions for treating ocular hypertension |
| US7129257B1 (en) | 2003-12-15 | 2006-10-31 | Alcon, Inc. | Pyrazolo[3,4- e]benzoxazoles for the treatment of glaucoma |
| US7338972B1 (en) | 2003-12-15 | 2008-03-04 | Alcon, Inc. | Substituted 1-alkylamino-1H-indazoles for the treatment of glaucoma |
| AR046890A1 (en) | 2003-12-15 | 2005-12-28 | Alcon Inc | [1,4] OXAZINO [2,3-G] SUBSTITUTED INDAZOLS FOR THE TREATMENT OF GLAUCOMA. |
| CN1988903A (en) | 2004-07-20 | 2007-06-27 | 默克公司 | Ophthalmic compositions for treating ocular hypertension |
| ATE460415T1 (en) | 2004-11-29 | 2010-03-15 | Warner Lambert Co | THERAPEUTIC PYRAZOLOA3,4-BUPYRIDINES AND INDAZOLES |
| US7425572B2 (en) | 2004-12-08 | 2008-09-16 | Alcon, Inc. | Use of dioxindoindazoles and dioxoloindazoles for treating glaucoma |
| CN101704785B (en) * | 2009-11-16 | 2012-02-29 | 东南大学 | Organic dicarboxylic acid and salts thereof and preparation method thereof |
| CN105884687B (en) * | 2016-04-14 | 2018-06-22 | 梯尔希（南京）药物研发有限公司 | A kind of preparation method of 5- benzyls benzydamine |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR9910590A (en) * | 1998-05-19 | 2001-01-23 | Alcon Lab Inc | Compound, process to decrease iop, to improve blood flow to the end of the optic nerve and the retina, and to treat retinal diseases, compositions to decrease iop, to improve blood flow to the end of the optic nerve and the retina, and to treating retinal diseases, process and composition to provide neuroprotection to the end of the optic nerve or the retina, and, process to treat people suffering from sleep disorders, depression, schizophrenia, anxiety, circadian rhythmic disorders and centrally and peripherally mediated hypertension |
| ES2204067T3 (en) * | 1998-05-26 | 2004-04-16 | Pfizer Products Inc. | MEDICINAL PRODUCT FOR THE TREATMENT OF GLAUCOMA AND ISCHEMICAL RETINOPATHY. |
| GB9819032D0 (en) * | 1998-09-01 | 1998-10-28 | Cerebrus Ltd | Chemical compounds IV |
| DK1112106T3 (en) * | 1998-09-18 | 2005-12-12 | Alcon Mfg Ltd | Serotonergic 5HT2 agonists for the treatment of glaucoma |
| GB9820767D0 (en) * | 1998-09-23 | 1998-11-18 | Cerebrus Ltd | Chemical compounds VIII |
-
2000
- 2000-11-14 PL PL00358481A patent/PL358481A1/en not_active Application Discontinuation
- 2000-11-14 EP EP00978628A patent/EP1268438A1/en not_active Withdrawn
- 2000-11-14 AU AU2001216072A patent/AU2001216072A1/en not_active Abandoned
- 2000-11-14 MX MXPA02008547A patent/MXPA02008547A/en unknown
- 2000-11-14 CA CA002402403A patent/CA2402403A1/en not_active Abandoned
- 2000-11-14 BR BR0017157-3A patent/BR0017157A/en not_active IP Right Cessation
- 2000-11-14 WO PCT/US2000/031247 patent/WO2001070702A1/en not_active Ceased
- 2000-11-14 JP JP2001568912A patent/JP2003528085A/en not_active Withdrawn
- 2000-11-14 CN CN00819346A patent/CN1450994A/en active Pending
- 2000-11-14 KR KR1020027011867A patent/KR20030065304A/en not_active Ceased
- 2000-11-27 TW TW089125127A patent/TWI221839B/en not_active IP Right Cessation
- 2000-12-01 AR ARP000106394A patent/AR032138A1/en not_active Application Discontinuation
- 2000-12-03 GC GCP20001082 patent/GC0000155A/en active
-
2002
- 2002-08-27 ZA ZA200206851A patent/ZA200206851B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BR0017157A (en) | 2002-11-26 |
| CA2402403A1 (en) | 2001-09-27 |
| JP2003528085A (en) | 2003-09-24 |
| MXPA02008547A (en) | 2003-03-12 |
| TWI221839B (en) | 2004-10-11 |
| AU2001216072A1 (en) | 2001-10-03 |
| ZA200206851B (en) | 2003-10-21 |
| GC0000155A (en) | 2005-06-29 |
| CN1450994A (en) | 2003-10-22 |
| EP1268438A1 (en) | 2003-01-02 |
| AR032138A1 (en) | 2003-10-29 |
| WO2001070702A1 (en) | 2001-09-27 |
| KR20030065304A (en) | 2003-08-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REFS | Decisions on refusal to grant patents (taken after the publication of the particulars of the applications) |