GR1011159B - Μεθοδος παρασκευης σταθερου συστηματος εγκλεισμου βιοενεργων συστατικων βασιλικου πολτου σε κυκλοδεξτρινες - Google Patents

Μεθοδος παρασκευης σταθερου συστηματος εγκλεισμου βιοενεργων συστατικων βασιλικου πολτου σε κυκλοδεξτρινες

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Publication number
GR1011159B
GR1011159B GR20250100108A GR20250100108A GR1011159B GR 1011159 B GR1011159 B GR 1011159B GR 20250100108 A GR20250100108 A GR 20250100108A GR 20250100108 A GR20250100108 A GR 20250100108A GR 1011159 B GR1011159 B GR 1011159B
Authority
GR
Greece
Prior art keywords
components
encapsulation
royal jelly
cyclodextrins
preparing
Prior art date
Application number
GR20250100108A
Other languages
English (en)
Inventor
Κωσταντινος Εμμανουηλ Γαρδικης
Μαρια Χρηστου Γκικα
Δαναη Ιωαννη Στυλιανου Γεωργιου
Σοφια Γεωργιου Αθανασοπουλου
Ελενη Ευαγγελου Σπανιδη
Ελενη Ιωαννη Παναγιωτιδου
Original Assignee
APIVITA ΚΑΛΛΥΝΤΙΚΑ-ΔΙΑΙΤΗΤΙΚΑ ΦΑΡΜΑΚΑ-ΑΝΩΝΥΜΗ ΕΜΠΟΡΙΚΗ ΚΑΙ ΒΙΟΤΕΧΝΙΚΗ ΕΤΑΙΡΕΙΑ με δ.τ. APIVITA,
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by APIVITA ΚΑΛΛΥΝΤΙΚΑ-ΔΙΑΙΤΗΤΙΚΑ ΦΑΡΜΑΚΑ-ΑΝΩΝΥΜΗ ΕΜΠΟΡΙΚΗ ΚΑΙ ΒΙΟΤΕΧΝΙΚΗ ΕΤΑΙΡΕΙΑ με δ.τ. APIVITA, filed Critical APIVITA ΚΑΛΛΥΝΤΙΚΑ-ΔΙΑΙΤΗΤΙΚΑ ΦΑΡΜΑΚΑ-ΑΝΩΝΥΜΗ ΕΜΠΟΡΙΚΗ ΚΑΙ ΒΙΟΤΕΧΝΙΚΗ ΕΤΑΙΡΕΙΑ με δ.τ. APIVITA,
Priority to GR20250100108A priority Critical patent/GR1011159B/el
Priority to PCT/EP2026/053277 priority patent/WO2026167219A1/en
Publication of GR1011159B publication Critical patent/GR1011159B/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/11—Encapsulated compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/63—Arthropods
    • A61K35/64—Insects, e.g. bees, wasps or fleas
    • A61K35/644—Beeswax; Propolis; Royal jelly; Honey
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/201—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having one or two double bonds, e.g. oleic, linoleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40—Cyclodextrins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/345—Alcohols containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/738—Cyclodextrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
    • A61K8/988—Honey; Royal jelly, Propolis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Insects & Arthropods (AREA)
  • Emergency Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Animal Husbandry (AREA)
  • Dispersion Chemistry (AREA)
  • Cosmetics (AREA)
  • Jellies, Jams, And Syrups (AREA)

Abstract

Μια μέθοδος παρασκευής σταθερού συστήματος εγκλεισμού βιοενεργών συστατικών φρέσκου βασιλικού πολτού σε κυκλοδεξτρίνες που προσφέρουν άμεση απελευθέρωση των συστατικών του, που προορίζεται τόσο για καλλυντική χρήση, όσο και για χρήση στο δέρμα και στο τριχωτό της που χαρακτηρίζεται από το ότι πραγματοποιείται ταυτόχρονη εκχύλιση και ενθυλάκωση βιοδραστικών συστατικών φρέσκου, μη επεξεργασμένου βασιλικού πολτού, σε ένα σύστημα υδροξυπρόπυλο β-κυκλοδεξτρίνης, το οποίο αποτελείται αποκλειστικά από φυσικά και ασφαλή συστατικά, και το οποίο προκαλεί μια άμεση απελευθέρωση των ενσωματωμένων πολυφαινολών και 10-HDA, ενώ τα ενσωματωμένα συστατικά διατηρούνται και προστατεύονται στο σύστημα για τουλάχιστον δέκα φορές περισσότερο χρόνο, από την ημερομηνία λήξης της πρώτης ύλης.
GR20250100108A 2025-02-07 2025-02-07 Μεθοδος παρασκευης σταθερου συστηματος εγκλεισμου βιοενεργων συστατικων βασιλικου πολτου σε κυκλοδεξτρινες GR1011159B (el)

Priority Applications (2)

Application Number Priority Date Filing Date Title
GR20250100108A GR1011159B (el) 2025-02-07 2025-02-07 Μεθοδος παρασκευης σταθερου συστηματος εγκλεισμου βιοενεργων συστατικων βασιλικου πολτου σε κυκλοδεξτρινες
PCT/EP2026/053277 WO2026167219A1 (en) 2025-02-07 2026-02-06 Method for the preparation of a stable encapsulation system of bioactive components of royal jelly in cyclodextrins

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GR20250100108A GR1011159B (el) 2025-02-07 2025-02-07 Μεθοδος παρασκευης σταθερου συστηματος εγκλεισμου βιοενεργων συστατικων βασιλικου πολτου σε κυκλοδεξτρινες

Publications (1)

Publication Number Publication Date
GR1011159B true GR1011159B (el) 2026-03-17

Family

ID=98776114

Family Applications (1)

Application Number Title Priority Date Filing Date
GR20250100108A GR1011159B (el) 2025-02-07 2025-02-07 Μεθοδος παρασκευης σταθερου συστηματος εγκλεισμου βιοενεργων συστατικων βασιλικου πολτου σε κυκλοδεξτρινες

Country Status (2)

Country Link
GR (1) GR1011159B (el)
WO (1) WO2026167219A1 (el)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6037942A (ja) * 1983-08-09 1985-02-27 Sanraku Inc 調製ローヤルゼリー配合物の製造法
JP2009082016A (ja) * 2007-09-27 2009-04-23 Matsuura Yakugyo Kk ローヤルゼリー中の１０−ヒドロキシ−２−デセン酸の安定化方法及びその方法によって得られるローヤルゼリーの粉末
WO2013141581A1 (ko) * 2012-03-19 2013-09-26 경희대학교 산학협력단 댕댕이나무열매 추출물을 유효성분으로 함유하는 허혈성 뇌혈관 질환의 예방 또는 개선용 약학적 조성물 또는 건강식품
WO2017055882A1 (en) * 2015-09-28 2017-04-06 Apivita S.A. Infusion obtained from a mixture of species of the sideritis plant for topical cutaneous or other use and production method therefor
GR1009544B (el) * 2017-07-11 2019-06-24 Apivita Καλλυντικα Διαιτητικα Φαρμακα Ανωνυμη Εμπορικη Και Βιοτεχνικη Εταιρεια Συνδυασμος εκχυλισματος δεντρολιβανου, εγχυματος δεντρολιβανου και εκχυλισματος ιπποφαους για τοπικη χρηση στο τριχωτο της κεφαλης και μεθοδος παραγωγης του
WO2021240183A1 (en) * 2020-05-27 2021-12-02 Apivita S.A. Preparation method of a colloidal system of stabilisation and contolled release of royal jelly components for various uses

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6037942A (ja) * 1983-08-09 1985-02-27 Sanraku Inc 調製ローヤルゼリー配合物の製造法
JP2009082016A (ja) * 2007-09-27 2009-04-23 Matsuura Yakugyo Kk ローヤルゼリー中の１０−ヒドロキシ−２−デセン酸の安定化方法及びその方法によって得られるローヤルゼリーの粉末
WO2013141581A1 (ko) * 2012-03-19 2013-09-26 경희대학교 산학협력단 댕댕이나무열매 추출물을 유효성분으로 함유하는 허혈성 뇌혈관 질환의 예방 또는 개선용 약학적 조성물 또는 건강식품
WO2017055882A1 (en) * 2015-09-28 2017-04-06 Apivita S.A. Infusion obtained from a mixture of species of the sideritis plant for topical cutaneous or other use and production method therefor
GR1009544B (el) * 2017-07-11 2019-06-24 Apivita Καλλυντικα Διαιτητικα Φαρμακα Ανωνυμη Εμπορικη Και Βιοτεχνικη Εταιρεια Συνδυασμος εκχυλισματος δεντρολιβανου, εγχυματος δεντρολιβανου και εκχυλισματος ιπποφαους για τοπικη χρηση στο τριχωτο της κεφαλης και μεθοδος παραγωγης του
WO2021240183A1 (en) * 2020-05-27 2021-12-02 Apivita S.A. Preparation method of a colloidal system of stabilisation and contolled release of royal jelly components for various uses

Also Published As

Publication number Publication date
WO2026167219A1 (en) 2026-08-13

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