AR080219A1 - Productos de membranas corionicas inmunocompatibles - Google Patents

Productos de membranas corionicas inmunocompatibles

Info

Publication number
AR080219A1
AR080219A1 ARP110100506A ARP110100506A AR080219A1 AR 080219 A1 AR080219 A1 AR 080219A1 AR P110100506 A ARP110100506 A AR P110100506A AR P110100506 A ARP110100506 A AR P110100506A AR 080219 A1 AR080219 A1 AR 080219A1
Authority
AR
Argentina
Prior art keywords
chorionic membrane
cells
placental
immunocompatible
products
Prior art date
Application number
ARP110100506A
Other languages
English (en)
Inventor
Jinqiang Kuang
Danilkovitch Alla
Jennifer Michelle Marconi
Timothy Jansen
Tom Samson
Yoo Dana
Original Assignee
Osiris Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Osiris Therapeutics Inc filed Critical Osiris Therapeutics Inc
Publication of AR080219A1 publication Critical patent/AR080219A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/12—Chemical aspects of preservation
    • A01N1/122—Preservation or perfusion media
    • A01N1/125—Freeze protecting agents, e.g. cryoprotectants or osmolarity regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/50—Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1825—Fibroblast growth factor [FGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1841—Transforming growth factor [TGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/57—Protease inhibitors from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0605—Cells from extra-embryonic tissues, e.g. placenta, amnion, yolk sac, Wharton's jelly
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/02—Atmosphere, e.g. low oxygen conditions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/02—Coculture with; Conditioned medium produced by embryonic cells
    • C12N2502/025—Coculture with; Conditioned medium produced by embryonic cells extra-embryonic cells, e.g. amniotic epithelium, placental cells, Wharton's jelly

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Reproductive Health (AREA)
  • Wood Science & Technology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Genetics & Genomics (AREA)
  • Gynecology & Obstetrics (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)

Abstract

Productos placentarios que comprenden una membrana corionica inmunocompatible. Estos productos placentarios pueden criopreservarse y contienen células terapéuticas viables una vez descongelados. Los productos placentarios de la presente son utiles para promover la cicatrizacion. Un método para proveer células madres en un tejido de un sujeto. El producto placentario se puede aplicar sobre es injerto. Reivindicacion 1: Un método para manufacturar un producto placentario, caracterizado porque comprende los siguientes pasos: a. obtener una placenta; b. eliminar selectivamente una porcion sustancial uno o más tipos de células inmunogénicas de la membrana corionica, donde i. los uno o más tipos de células inmunogénicas comprenden trofoblastos, macrofagos CD14+ funcionales o trofoblastos y macrofagos CD14+ funcionales; y ii. el paso de eliminacion selectiva no comprende exterminar o remover sustancialmente la totalidad de las células terapéuticas, que se seleccionan entre las MSC, los fibroblastos o una combinacion de éstos; y c. criopreservar la membrana corionica en un medio de criopreservacion; y d. opcionalmente, eliminar sustancialmente la totalidad del tejido vascularizado o de las células inmunogénicas derivadas del tejido vascularizado de la placenta o de la membrana corionica correspondiente.
ARP110100506A 2010-02-18 2011-02-18 Productos de membranas corionicas inmunocompatibles AR080219A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33846410P 2010-02-18 2010-02-18
US33848910P 2010-02-18 2010-02-18
US36956210P 2010-07-30 2010-07-30

Publications (1)

Publication Number Publication Date
AR080219A1 true AR080219A1 (es) 2012-03-21

Family

ID=44476694

Family Applications (6)

Application Number Title Priority Date Filing Date
ARP110100505A AR080218A1 (es) 2010-02-18 2011-02-18 Productos de membranas corionicas inmunocompatibles
ARP110100509A AR080222A1 (es) 2010-02-18 2011-02-18 Productos terapeuticos que comprenden dispersiones placentarias vitalizadas
ARP110100508A AR080221A1 (es) 2010-02-18 2011-02-18 Productos de membranas amnioticas inmunocompatibles
ARP110100510A AR080223A1 (es) 2010-02-18 2011-02-18 Productos terapeuticos que comprenden dispersiones placentarias vitalizadas
ARP110100507A AR080220A1 (es) 2010-02-18 2011-02-18 Productos de membranas amnioticas inmunocompatibles
ARP110100506A AR080219A1 (es) 2010-02-18 2011-02-18 Productos de membranas corionicas inmunocompatibles

Family Applications Before (5)

Application Number Title Priority Date Filing Date
ARP110100505A AR080218A1 (es) 2010-02-18 2011-02-18 Productos de membranas corionicas inmunocompatibles
ARP110100509A AR080222A1 (es) 2010-02-18 2011-02-18 Productos terapeuticos que comprenden dispersiones placentarias vitalizadas
ARP110100508A AR080221A1 (es) 2010-02-18 2011-02-18 Productos de membranas amnioticas inmunocompatibles
ARP110100510A AR080223A1 (es) 2010-02-18 2011-02-18 Productos terapeuticos que comprenden dispersiones placentarias vitalizadas
ARP110100507A AR080220A1 (es) 2010-02-18 2011-02-18 Productos de membranas amnioticas inmunocompatibles

Country Status (6)

Country Link
US (28) US20110206776A1 (es)
EP (10) EP3351625A1 (es)
AR (6) AR080218A1 (es)
CA (6) CA2790322A1 (es)
ES (2) ES2665466T3 (es)
WO (6) WO2011103470A1 (es)

Families Citing this family (109)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2408207A (en) * 2003-11-24 2005-05-25 Johnson & Johnson Medical Ltd Wound dressing for the controlled release of therapeutic agents comprising also an inhibitor of a protease enzyme & a linker group cleavable by such an enzyme
US8182840B2 (en) 2005-09-27 2012-05-22 Tissue Tech, Inc. Amniotic membrane preparations and purified compositions and therapy for scar reversal and inhibition
US8187639B2 (en) 2005-09-27 2012-05-29 Tissue Tech, Inc. Amniotic membrane preparations and purified compositions and anti-angiogenesis treatment
US8372437B2 (en) 2006-08-17 2013-02-12 Mimedx Group, Inc. Placental tissue grafts
DE102007007664B3 (de) 2007-02-13 2008-03-27 Mokveld Valves B.V. Drosselventil
EP4559488A3 (en) 2007-09-07 2025-08-13 MiMedx Group, Inc. Placental tissue grafts and improved methods of preparing and using the same
US9301679B2 (en) 2007-11-01 2016-04-05 Dignity Health Method of detecting neurological disease
US9358320B2 (en) 2008-04-25 2016-06-07 Allosource Multi-layer tissue patches
US9480549B2 (en) 2008-04-25 2016-11-01 Allosource Multi-layer tissue patches
US9192695B2 (en) 2008-11-20 2015-11-24 Allosource Allografts combined with tissue derived stem cells for bone healing
JP5693475B2 (ja) 2009-03-04 2015-04-01 ペイタント・ソリューションズ・インコーポレイテッドＰｅｙｔａｎｔ Ｓｏｌｕｔｉｏｎｓ， Ｉｎｃ． 羊膜組織を含む材料で修飾されたステント及び対応する方法
US20140286911A1 (en) 2013-03-15 2014-09-25 Allosource Cell repopulated collagen matrix for soft tissue repair and regeneration
EP3351625A1 (en) 2010-02-18 2018-07-25 Osiris Therapeutics, Inc. Methods of manufacture of immunocompatible amniotic membrane products
US9352003B1 (en) 2010-05-14 2016-05-31 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US8883210B1 (en) 2010-05-14 2014-11-11 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US20130156863A1 (en) * 2010-06-30 2013-06-20 Tissuetech, Inc. Methods of preparing chorion tissue and products derived therefrom
WO2012103470A2 (en) 2011-01-28 2012-08-02 Dignity Health Method of detecting neurological disease
WO2012112441A1 (en) * 2011-02-14 2012-08-23 Mimedx Group Inc. Laminated tissue grafts composed of wharton's jelly and methods of making and using the same
KR102903446B1 (ko) 2011-02-14 2025-12-24 미메딕스 그룹 인크. 마이크로화된 태반 조직 조성물 및 이의 제조 및 사용 방법
US9526770B2 (en) 2011-04-28 2016-12-27 Tissuetech, Inc. Methods of modulating bone remodeling
ES2822301T3 (es) 2011-06-10 2021-04-30 Tissuetech Inc Métodos de procesamiento de tejidos de soporte fetal
US12290613B2 (en) 2011-10-06 2025-05-06 Mimedx Group, Inc. Micronized compositions composed of bone grafts and methods of making and using the same
US8932805B1 (en) 2011-10-31 2015-01-13 BioDlogics, LLC Birth tissue material and method of preparation
US9162011B2 (en) 2011-12-19 2015-10-20 Allosource Flowable matrix compositions and methods
WO2013096659A1 (en) * 2011-12-20 2013-06-27 Cook General Biotechnology Llc Methods and compositions for storage of animal cells
US9416410B2 (en) * 2012-02-14 2016-08-16 Genetics Development Corporation Cutoff point delta Ct. method for HER2 PCR testing in breast cancer
US20130236506A1 (en) * 2012-03-08 2013-09-12 AFcell Medical Amnion and chorion constructs and uses thereof in ob-gyn surgery
US8961617B2 (en) 2012-03-08 2015-02-24 Liventa Bioscience, Inc. Amnion and chorion constructs and uses thereof in abdominal surgery
US8904664B2 (en) 2012-08-15 2014-12-09 Mimedx Group, Inc. Dehydration device and methods for drying biological materials
US9943551B2 (en) 2012-08-15 2018-04-17 Mimedx Group, Inc. Tissue grafts composed of micronized placental tissue and methods of making and using the same
US10857266B2 (en) 2012-08-15 2020-12-08 Mimedx Group, Inc. Reinforced placental tissue grafts and methods of making and using the same
EP2897625B1 (en) 2012-09-10 2019-10-23 Wake Forest University Health Sciences Amniotic membrane and its use in wound healing and tissue engineering constructs
US9180145B2 (en) 2012-10-12 2015-11-10 Mimedx Group, Inc. Compositions and methods for recruiting and localizing stem cells
US8946163B2 (en) 2012-11-19 2015-02-03 Mimedx Group, Inc. Cross-linked collagen comprising metallic anticancer agents
US9155799B2 (en) 2012-11-19 2015-10-13 Mimedx Group, Inc. Cross-linked collagen with at least one bound antimicrobial agent for in vivo release of the agent
US10111910B2 (en) 2013-01-18 2018-10-30 Mimedx Group, Inc. Methods for treating cardiac conditions
US10206977B1 (en) 2013-01-18 2019-02-19 Mimedx Group, Inc. Isolated placental stem cell recruiting factors
US20140212390A1 (en) * 2013-01-30 2014-07-31 NuTech Medical, Inc. Placental Membrane Preparation and Methods of Making and Using Same
EP2951289B1 (en) * 2013-01-30 2019-10-02 Nutech Medical, Inc. Placental membrane preparation and methods of making and using same
US9616093B2 (en) * 2013-01-30 2017-04-11 NuTech Medical, Inc. Placental membrane preparation and methods of making and using same
US11077229B1 (en) 2013-03-08 2021-08-03 BioDlogics, LLC Implant coating composition and method of use
US9770472B1 (en) * 2013-03-08 2017-09-26 Brahm Holdings, Llc Organ jacket and methods of use
AU2014248873B2 (en) 2013-03-13 2017-03-23 Allosource Fascia fibrous compositions and methods for their use and manufacture
US20160379205A1 (en) 2013-03-15 2016-12-29 Apple Inc. Facilitating transactions with a user account using a wireless device
US10029030B2 (en) 2013-03-15 2018-07-24 Mimedx Group, Inc. Molded placental tissue compositions and methods of making and using the same
US10555897B1 (en) 2013-03-16 2020-02-11 Brahm Holdings Llc Cosmetic composition and methods of treatment
US9993506B1 (en) 2013-03-16 2018-06-12 BioDlogics, Inc. Methods for the treatment of degenerative disc diseases by human birth tissue material composition
US10039792B1 (en) 2013-03-16 2018-08-07 Brahm Holdings, Llc Methods for the treatment of inflammation and pain using human birth tissue material composition
US9795639B1 (en) 2013-03-16 2017-10-24 BioDlogics, LLC Methods for the treatment of erectile dysfunction by human birth tissue material compostion
US9446142B2 (en) 2013-05-28 2016-09-20 Mimedx Group, Inc. Polymer chelator conjugates
US20160193250A1 (en) * 2013-05-30 2016-07-07 Cells For Cells Chorion-derived mscs cells and conditioned media as inducer for angiogenesis application for the treatment of cardiac degeneration.
JP6512759B2 (ja) 2013-08-19 2019-05-15 国立研究開発法人国立循環器病研究センター 羊膜間葉系細胞組成物の製造方法及び凍結保存方法、並びに治療剤
US10449220B2 (en) 2013-08-30 2019-10-22 Mimedx Group, Inc. Micronized placental compositions comprising a chelator
CN104560862B (zh) * 2013-10-14 2019-09-13 佛教慈济医疗财团法人 分离脂肪组织活细胞方法、医药组合物及其用途、细胞库
KR101832203B1 (ko) 2013-12-06 2018-02-27 알로소스 조직의 시트를 건조하는 방법
EP3094336A4 (en) * 2014-01-17 2018-02-14 MIMEDX Group Inc. Method for inducing angiogenesis
US9856454B2 (en) 2014-02-27 2018-01-02 Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation Rapid mincing of adipose tissues to isolate live cells in vitro
SG11201609253PA (en) * 2014-05-07 2016-12-29 Osiris Therapeutics Inc Immunocompatible chorionic membrane products
JP2017514879A (ja) * 2014-05-07 2017-06-08 オシリス セラピューティクス，インコーポレイテッド 免疫適合性のある羊膜生成物
JP2017514876A (ja) * 2014-05-07 2017-06-08 オシリス セラピューティクス，インコーポレイテッド 治療用胎盤組成物、その製造法及び使用法
TW201603818A (zh) 2014-06-03 2016-02-01 組織科技股份有限公司 組成物及方法
WO2016029019A1 (en) 2014-08-21 2016-02-25 Dignity Health Systems and methods for using eye movements to determine traumatic brain injury
EP3185918B1 (en) 2014-08-28 2021-08-18 MiMedx Group, Inc. Collagen reinforced tissue grafts
WO2016044030A1 (en) 2014-09-19 2016-03-24 Osiris Therapeutics, Inc. Bone repair product and methods of use thereof
EP3200809B1 (en) 2014-10-02 2023-09-13 Wake Forest University Health Sciences, Inc. Amniotic membrane powder and its use in wound healing and tissue engineering constructs
US20160095307A1 (en) * 2014-10-07 2016-04-07 NuTech Medical, Inc. Method and composition for hypothermic storage of placental tissue
US10201573B1 (en) 2014-10-27 2019-02-12 Brahm Holdings, Llc Human birth tissue material composition and methods for the treatment of damage associated with a cerebral vascular accident
US10265438B1 (en) 2014-11-03 2019-04-23 BioDlogics, LLC Methods and compositions for the repair and replacement of connective tissue
US10765705B2 (en) 2014-11-24 2020-09-08 Prime Merger Sub, Llc Visco-supplement compositions, and methods of use thereof
WO2016109826A1 (en) * 2014-12-31 2016-07-07 Applied Biologics, Llc Standardized amniotic membrane tissue graft
US20160243288A1 (en) 2015-02-23 2016-08-25 Tissuetech, Inc. Apparatuses and methods for treating ophthalmic diseases and disorders
JP2018516869A (ja) 2015-05-20 2018-06-28 ティッシュテック，インク． 上皮細胞の増殖および上皮間葉転換を防ぐための組成物および方法
ES2887588T3 (es) * 2015-08-13 2021-12-23 Kamada Ltd Composiciones derivadas de pasta de fracción de Cohn y uso de las mismas
US12551509B2 (en) 2015-11-18 2026-02-17 Lucina Patent Holdco, Llc Acellular regenerative products and methods of their manufacture
US11207446B2 (en) 2015-12-23 2021-12-28 Lifenet Health Decellularized placental membrane and methods of preparing and use thereof
US20190290802A1 (en) * 2016-01-08 2019-09-26 Cryolife, Inc. Human placental tissue graft products, methods, and apparatuses
TW201733600A (zh) 2016-01-29 2017-10-01 帝聖工業公司 胎兒扶持組織物及使用方法
CN109069867B (zh) * 2016-03-14 2022-02-01 无痛疗法股份有限公司 无细胞胎盘制剂
CA3029233A1 (en) 2016-06-24 2017-12-28 Osiris Therapeutics, Inc. Human tissue derived compositions and uses thereof
WO2017223520A1 (en) * 2016-06-24 2017-12-28 Osiris Therapeutics, Inc. Viable lyophilized compositions derived from human tissues and methods of making the same
US12161688B2 (en) 2016-06-30 2024-12-10 Mapi Pharma Ltd Treatment of inflammatory bowel disease with long acting glatiramer and adipose-derived stem cells
AU2017316682B2 (en) 2016-08-24 2020-10-15 Arthrex, Inc. Tissue use for repair of injury
US10772986B2 (en) 2017-01-26 2020-09-15 Allosource Fascia fibrous compositions and methods for their use and manufacture
WO2018144694A1 (en) 2017-02-01 2018-08-09 Plakous Therapeutics, Inc. Placental tissue compositions
CN106834257B (zh) * 2017-03-23 2020-06-30 天晴干细胞股份有限公司 一种分离胎盘间充质干细胞混合酶及其分离方法
WO2018211486A1 (en) 2017-05-15 2018-11-22 Stem Cell Medicine Ltd. Treatment of multiple sclerosis with long acting glatiramer and adipose-derived stem cells
AU2018270396B2 (en) 2017-05-15 2025-03-20 Stem Cell Medicine Ltd. Treatment of multiple sclerosis with adipose-derived stem cells
CN107254431B (zh) * 2017-05-25 2020-08-18 林翠霞 一种新型组织工程皮肤制备方法
CN107296041B (zh) * 2017-07-02 2020-12-25 江西瑞济生物工程技术股份有限公司 一种新鲜羊膜保存液及新鲜羊膜保存方法与应用
GB2582521B (en) 2017-11-14 2022-07-13 Cook Biotech Inc Preserved tissue products and related methods
CN107779429A (zh) * 2017-12-07 2018-03-09 陕西九州生物医药科技集团有限公司 一种人皮肤组织来源成纤维细胞快速分离培养方法
CN109652363A (zh) * 2018-11-13 2019-04-19 广东唯泰生物科技有限公司 胎盘壁蜕膜间充质干细胞分化为子宫内膜上皮细胞的方法
CA3123408A1 (en) * 2018-12-16 2020-06-25 Figene, Llc Therapeutic uses of gene edited fibroblasts
US11511017B2 (en) 2019-03-12 2022-11-29 Arthrex, Inc. Ligament reconstruction
WO2020201488A1 (en) * 2019-04-04 2020-10-08 Hackethal Johannes A novel human-material-based platform technology for tissue engineering
CN110144322A (zh) * 2019-04-15 2019-08-20 湖南南华爱世普林生物技术有限公司 一种胎盘间充质干细胞快速分离与培养至收获冻存的方法
AU2020260133A1 (en) * 2019-04-16 2021-11-18 Lifenet Health Birth tissue-derived products and preparation and uses thereof
CN110141686B (zh) * 2019-05-07 2021-11-02 吉林省海创生物科技有限公司 一种人脐带间充质干细胞注射液及其面部填充注射方法
CN110179679A (zh) * 2019-06-25 2019-08-30 贵州医科大学 含脐带间充质干细胞培养液提取物的生物养颜修护面膜精华、面膜及其制备方法
WO2021003257A1 (en) * 2019-07-01 2021-01-07 Auxocell Laboratories, Inc. Methods and compositions for collecting and using placental tissue cells and placental blood cells
WO2021123320A1 (en) * 2019-12-20 2021-06-24 Dr. Kalali Prof. Mostafazadeh Dipl. Ing. Miedl (Kmm) Gesellschaft Bürgerlichen Rechts A composition and its use for a universal therapy against tumor cells
US20230047934A1 (en) * 2020-03-12 2023-02-16 Osiris Therapeutics, Inc. Human tissue derived compositions and uses thereof
WO2022074523A1 (en) 2020-10-06 2022-04-14 Osiris Therapeutics, Inc. Primed placental tissue and uses in regenerative medicine
WO2022098774A1 (en) 2020-11-06 2022-05-12 Smith & Nephew, Inc. Graft composite for hip labrum reconstruction
AR124837A1 (es) * 2021-02-09 2023-05-10 Millennium Pharm Inc Métodos y composiciones para congelar y descongelar células de mamíferos
KR102523933B1 (ko) * 2021-05-03 2023-04-20 고려대학교 산학협력단 융모막 추출물로부터 분리된 엑소좀을 유효성분으로 포함하는 골형성 촉진용 약학적 조성물
US20250144210A1 (en) * 2022-02-01 2025-05-08 Seattle Children’s Hospital d/b/a Seattle Children’s Research Institute Simplified method of preparing cells for patient administration
US12594363B2 (en) * 2022-03-01 2026-04-07 XoBiologix, L.L.C. Enhanced biologic grafts with packaging apparatuses, and methods of use
WO2024020135A1 (en) * 2022-07-21 2024-01-25 Biostem Technologies, Inc. Collection and quantification of elements per square centimeter in a human placental membrane allograft

Family Cites Families (74)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8803697D0 (en) 1988-02-17 1988-03-16 Deltanine Research Ltd Clinical developments using amniotic membrane cells
US5891617A (en) * 1993-09-15 1999-04-06 Organogenesis Inc. Cryopreservation of harvested skin and cultured skin or cornea equivalents by slow freezing
US6152142A (en) * 1997-02-28 2000-11-28 Tseng; Scheffer C. G. Grafts made from amniotic membrane; methods of separating, preserving, and using such grafts in surgeries
AU2005202256B2 (en) * 1999-11-05 2008-04-03 Gerigene Medical Corporation Augmentation and repair of age-related soft tissue defects
US7331350B2 (en) 2000-02-11 2008-02-19 The General Hospital Corporation Photochemical tissue bonding
US7582292B2 (en) * 2000-02-26 2009-09-01 Artecel, Inc. Adipose tissue derived stromal cells for the treatment of neurological disorders
US20020039788A1 (en) 2000-02-29 2002-04-04 Isseroff Roslyn R. Corneal epithelial graft composites
US7504374B2 (en) * 2000-10-24 2009-03-17 Warsaw Orthopedic, Inc. Method for inducing deposition and maturation of bone comprising a co-therapeutic regimen of LMP-1 and BMP-2
US20080152629A1 (en) 2000-12-06 2008-06-26 James Edinger Placental stem cell populations
ES2432493T3 (es) 2001-02-14 2013-12-03 Anthrogenesis Corporation Placenta de mamífero post-parto, su uso y células madre de la misma
EP2316918B1 (en) * 2001-02-14 2015-07-01 Anthrogenesis Corporation Post-partum mammalian placenta, its use and placental stem cells therefrom
CA2445826C (en) * 2001-05-02 2014-03-25 Purdue Research Foundation Treatment and diagnosis of macrophage mediated disease
JP4330995B2 (ja) * 2001-11-15 2009-09-16 チルドレンズ メディカル センター コーポレーション 絨毛膜絨毛、羊水、および胎盤からの胎児性幹細胞を単離、増殖、および分化させる方法、ならびにその治療的使用方法
US20070134261A1 (en) * 2001-12-03 2007-06-14 Hancock Robert E Effectors of innate immunity
US20030187515A1 (en) * 2002-03-26 2003-10-02 Hariri Robert J. Collagen biofabric and methods of preparing and using the collagen biofabric
US20030235563A1 (en) * 2002-04-19 2003-12-25 Strom Stephen C. Placental derived stem cells and uses thereof
WO2004032969A1 (en) * 2002-10-09 2004-04-22 Lorantis Limited Modulation of immune function
US7993922B2 (en) * 2002-10-18 2011-08-09 Reliance Life Sciences Pvt. Ltd. Three-dimensional tissue equivalent using macromass culture
WO2005007835A1 (en) 2003-06-16 2005-01-27 Zephan Biopharmaceuticals, Inc. Methods of preparing a transplantable product for treatment of skin defects
EP2399990B1 (en) * 2003-06-27 2015-07-22 DePuy Synthes Products, Inc. Cells derived from post-partum umbilical cord for use in treatment of disease of the heart and circulatory system
WO2005021014A1 (fr) 2003-09-03 2005-03-10 Jiuchang Miao Preparation d'un amnios biologique conservable a temperature ambiante
GB2408207A (en) 2003-11-24 2005-05-25 Johnson & Johnson Medical Ltd Wound dressing for the controlled release of therapeutic agents comprising also an inhibitor of a protease enzyme & a linker group cleavable by such an enzyme
US20050176139A1 (en) 2004-01-12 2005-08-11 Yao-Chang Chen Placental stem cell and methods thereof
US7244444B2 (en) * 2004-03-31 2007-07-17 Cook Incorporated Graft material, stent graft and method
US7280326B2 (en) * 2004-07-30 2007-10-09 Hitachi Global Storage Technologies Netherlands B.V. Trilayer SAF with current confining layer
PL369552A1 (pl) 2004-08-12 2006-02-20 Sgp & Sons Ab Preparat farmaceutyczny lub/i żywieniowy lub/i laboratoryjny wzmagający, wspomagający funkcjonowanie komórek nerwowych i układu nerwowego oraz zastosowanie preparatu farmaceutycznego lub/i żywieniowego w procesie ochrony funkcji układu nerwowego oraz zastosowanie preparatu do ochrony wzrostu stymulacji namnażania i zapobiegania apoptozie komórek nerwowych
US20060111778A1 (en) 2004-10-29 2006-05-25 Michalow Alexander E Methods of promoting healing of cartilage defects and method of causing stem cells to differentiate by the articular chondrocyte pathway
US20080213332A1 (en) * 2004-11-10 2008-09-04 Shimon Slavin Cells Isolated from Placenta, Device for Isolating Same, and Uses Thereof
CA2589041C (en) * 2004-12-23 2019-08-20 DePuy Synthes Products, Inc. Postpartum cells derived from umbilical cord tissue, and methods of making and using the same
WO2006088867A2 (en) * 2005-02-15 2006-08-24 Medistem Laboratories, Incorporated Method for expansion of stem cells
WO2006094247A2 (en) * 2005-03-02 2006-09-08 Tissuetech, Inc. Amniotic membrane extracts, compositions thereof, and methods of use
US20070015278A1 (en) * 2005-04-13 2007-01-18 Yuling Li Methods of isolating differentiable cells from placental-associated tissue and uses thereof
US7928280B2 (en) 2005-07-13 2011-04-19 Anthrogenesis Corporation Treatment of leg ulcers using placenta derived collagen biofabric
WO2007011693A2 (en) * 2005-07-14 2007-01-25 Medistem Laboratories, Inc. Compositions of placentally-derived stem cells for the treatment of cancer
GB0514567D0 (en) * 2005-07-15 2005-08-24 Univ Nottingham Surgical membrane
US8932641B2 (en) 2005-08-26 2015-01-13 Amnos Co., Ltd. Dried amnion and method for drying treatment of amnion
US8182840B2 (en) * 2005-09-27 2012-05-22 Tissue Tech, Inc. Amniotic membrane preparations and purified compositions and therapy for scar reversal and inhibition
ZA200803929B (en) * 2005-10-13 2009-08-26 Anthrogenesis Corp Production of oligodendrocytes from placenta-derived stem cells
PL2471907T3 (pl) * 2005-12-29 2019-07-31 Celularity, Inc. Populacje komórek macierzystych łożyska
EP1976978A2 (en) * 2005-12-29 2008-10-08 Anthrogenesis Corporation Co-culture of placental stem cells and stem cells from a second source
US8871198B2 (en) * 2006-03-29 2014-10-28 Stemnion, Inc. Methods related to wound healing
US20070178159A1 (en) * 2006-01-30 2007-08-02 Alza Corporation In-Situ Forming Porous Scaffold
WO2007146106A2 (en) * 2006-06-05 2007-12-21 Cryo- Cell International, Inc. Procurement, isolation and cryopreservation of maternal placental cells
KR20090031895A (ko) * 2006-06-09 2009-03-30 안트로제네시스 코포레이션 태반 니치 및 줄기 세포 배양을 위한 이의 용도
WO2008021391A1 (en) * 2006-08-15 2008-02-21 Anthrogenesis Corporation Umbilical cord biomaterial for medical use
US8372437B2 (en) 2006-08-17 2013-02-12 Mimedx Group, Inc. Placental tissue grafts
WO2008042441A1 (en) * 2006-10-03 2008-04-10 Anthrogenesis Corporation Use of umbilical cord biomaterial for ocular surgery
WO2008060377A2 (en) 2006-10-04 2008-05-22 Anthrogenesis Corporation Placental or umbilical cord tissue compositions
CN102940878A (zh) * 2006-10-06 2013-02-27 Scil技术股份有限公司 脊柱髓核植入物
CN101622007A (zh) * 2006-10-06 2010-01-06 人类起源公司 天然(端肽)胎盘胶原组合物
US8562972B2 (en) 2006-10-23 2013-10-22 Anthrogenesis Corporation Methods and compositions for treatment of bone defects with placental cell populations
NZ612888A (en) * 2007-02-12 2015-02-27 Anthrogenesis Corp Treatment of inflammatory diseases using placental stem cells
US8414929B2 (en) * 2007-02-23 2013-04-09 National University Corporation University Of Toyama Medical substitute membrane, use thereof, and method for repair of membrane tissue in living body
KR20080104844A (ko) * 2007-05-29 2008-12-03 포천중문의과대학교 산학협력단 태반-유래 영양막 줄기 세포의 분리방법
EP2014767A1 (en) * 2007-06-15 2009-01-14 Centro di Ricerca E. Menni T cell immunomodulation by placenta cell preparations
CA2688504A1 (en) * 2007-06-18 2008-12-24 Children's Hospital & Research Center At Oakland Method of isolating stem and progenitor cells from placenta
US8198245B2 (en) * 2007-07-27 2012-06-12 Humacyte, Inc. Compositions and methods for soft tissue augmentation
KR20220122774A (ko) * 2007-09-26 2022-09-02 셀룰래리티 인코포레이티드 인간 태반 관류액으로부터의 혈관형성 세포
RU2536242C2 (ru) * 2007-09-28 2014-12-20 Антродженезис Корпорейшн Угнетение опухолей с помощью плацентарного перфузата человека и выделенных из плаценты человека вспомогательных натуральных клеток-киллеров
WO2009044408A1 (en) 2007-10-03 2009-04-09 International Centre For Cardio Thoracic And Vascular Diseases (A Unit Of Frontier Lifeline Pvt. Ltd) A treated amniotic membrane and method of treating amniotic membrane
UA99167C2 (ru) * 2007-12-27 2012-07-25 Этикон, Инкорпорейтед Лечение дегенерации межреберных дисков с использованием клеток, полученных из ткани пуповины человека
EP2271209B1 (en) 2008-03-27 2016-07-13 Biolife Solutions, Inc. Materials and methods for hypothermic collection of whole blood
CA2722475A1 (en) 2008-04-25 2009-10-29 Allosource Anti-adhesion barrier wound dressing comprising processed amniotic tissue and method of use
CA2734237C (en) * 2008-08-20 2019-07-02 Anthrogenesis Corporation Treatment of stroke using isolated placental cells
WO2011074208A1 (ja) 2009-12-18 2011-06-23 国立大学法人東北大学 皮膚真皮又は羊膜透明化による角膜移植材料調製法
US20150010506A1 (en) 2010-02-18 2015-01-08 Osiris Therapeutics, Inc. Therapeutic placental compositions, methods of making and methods of use
US20150010609A1 (en) 2010-02-18 2015-01-08 Osiris Therapeutics, Inc. Immunocompatible chorionic membrane products
US20150010610A1 (en) 2010-02-18 2015-01-08 Osiris Therapeutics, Inc. Immunocompatible amniotic membrane products
EP3351625A1 (en) 2010-02-18 2018-07-25 Osiris Therapeutics, Inc. Methods of manufacture of immunocompatible amniotic membrane products
US8632512B2 (en) 2010-04-09 2014-01-21 Kci Licensing, Inc. Apparatuses, methods, and compositions for the treatment and prophylaxis of chronic wounds
JP2014115445A (ja) 2012-12-10 2014-06-26 Funai Electric Co Ltd 光学装置
JP2017514879A (ja) 2014-05-07 2017-06-08 オシリス セラピューティクス，インコーポレイテッド 免疫適合性のある羊膜生成物
SG11201609253PA (en) 2014-05-07 2016-12-29 Osiris Therapeutics Inc Immunocompatible chorionic membrane products
JP2017514876A (ja) 2014-05-07 2017-06-08 オシリス セラピューティクス，インコーポレイテッド 治療用胎盤組成物、その製造法及び使用法

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