GR18318B - METHOD OF PREPARATION OF TETRAKILINE. - Google Patents

METHOD OF PREPARATION OF TETRAKILINE.

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Publication number
GR18318B
GR18318B GR570118318A GR570118318A GR18318B GR 18318 B GR18318 B GR 18318B GR 570118318 A GR570118318 A GR 570118318A GR 570118318 A GR570118318 A GR 570118318A GR 18318 B GR18318 B GR 18318B
Authority
GR
Greece
Prior art keywords
lower alkyl
phenyl
tetracycline
tetrakiline
preparation
Prior art date
Application number
GR570118318A
Other languages
Greek (el)
Original Assignee
American Cyanamid Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Company filed Critical American Cyanamid Company
Priority to GR570118318A priority Critical patent/GR18318B/en
Publication of GR18318B publication Critical patent/GR18318B/en

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  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

ία μέθοδος παραγωγής τετρακυκλίνης χαρακτηριζομένη εκ της υπό αεροβίου συνθήκας ζυμώσεως ενός υδατικού μέσου ζυμώσεως περιέχοντος ιόντα χλωριδίνω, τηβοηθεία ενόςμικροοργανισμού του γένους στρεπτομύκητος, και της προσθήκης, είς το ρηθέν μέσον, ενόςπαράγοντος παρεμποδίσεως της χλωριώσεως έχοντος το τύπο (Ι) είςτον οποίον το Χ είναι υδρογόνον ή μία κατωτέρα αλκυλική ρίζα, το Χ είνα υδρογόνον, φαινύλιον, αμίνη, κατώτερον αλκύλιον, ή η ομάς (ΙΙ) ένθα το R είναι φαινύλιον ή κατώτερον αλκυλοφαινύλιον, και το Ζ είναι έν μέλος εκ των ομάδων αίτινες αποτελούνται εξ S (κατωτέρου αλκυλίου), συνεπεία του οποίου παρεμποδίζεται ο σχηματισμός χλωροτετρακυκλίνης και παράγοντα σημαντικαί ποσότητες τετρακυκλίνης. A method of producing tetracycline characterized by the aerobic fermentation condition of an aqueous fermentation medium containing chloride ions, assisted by a microorganism of the genus Streptomycosis, and the addition, to the said medium or a lower alkyl radical, X is hydrogen, phenyl, amine, lower alkyl, or the group (II) wherein R is phenyl or lower alkylphenyl, and Z is a member of the causal groups consisting of S (lower alkyl) , as a result of which the formation of chlorotetracycline is inhibited and a significant amount of tetracycline is produced.

GR570118318A 1957-10-31 1957-10-31 METHOD OF PREPARATION OF TETRAKILINE. GR18318B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GR570118318A GR18318B (en) 1957-10-31 1957-10-31 METHOD OF PREPARATION OF TETRAKILINE.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GR570118318A GR18318B (en) 1957-10-31 1957-10-31 METHOD OF PREPARATION OF TETRAKILINE.

Publications (1)

Publication Number Publication Date
GR18318B true GR18318B (en) 1957-11-30

Family

ID=36859503

Family Applications (1)

Application Number Title Priority Date Filing Date
GR570118318A GR18318B (en) 1957-10-31 1957-10-31 METHOD OF PREPARATION OF TETRAKILINE.

Country Status (1)

Country Link
GR (1) GR18318B (en)

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