GR3000878T3 - Halogenides of the ester of 2,n,n,n-dimethyl-alkyl-amino-ethanol with substituted acetic acid and pharmaceutical compositions having antiinflammatory and antiseptic activities containing same - Google Patents

Halogenides of the ester of 2,n,n,n-dimethyl-alkyl-amino-ethanol with substituted acetic acid and pharmaceutical compositions having antiinflammatory and antiseptic activities containing same

Info

Publication number: GR3000878T3
Authority: GR; Greece
Prior art keywords: alkyl; halogenides; dimethyl; ethanol; ester
Prior art date: 1986-03-04

Application number

GR90400682T

Other languages

English (en)

Inventor

Alberto Reiner

Original Assignee

Sigma Tau Ind Farmaceuti

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-03-04

Filing date

1990-09-27

Publication date

1991-11-15

1990-09-27 Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti

1991-11-15 Publication of GR3000878T3 publication Critical patent/GR3000878T3/el

Links

QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Natural products CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 title abstract 4
125000000218 acetic acid group Chemical class C(C)(=O)* 0.000 title abstract 2
230000003110 anti-inflammatory effect Effects 0.000 title abstract 2
230000002421 anti-septic effect Effects 0.000 title abstract 2
150000002148 esters Chemical class 0.000 title abstract 2
239000008194 pharmaceutical composition Chemical class 0.000 title 1
-1 p-isobutylphenyl Chemical group 0.000 abstract 3
125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Indole Compounds (AREA)

GR90400682T 1986-03-04 1990-09-27 Halogenides of the ester of 2,n,n,n-dimethyl-alkyl-amino-ethanol with substituted acetic acid and pharmaceutical compositions having antiinflammatory and antiseptic activities containing same GR3000878T3 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT8647711A IT1208736B (it)	1986-03-04	1986-03-04	Alogenuri dell'estere del 2-n,n,n,dimetil-alchil-amminoetanolo con acido acetico variamente sostituito e composizioni farmaceutiche che licontengono ad attivita' antiinfiammatoria e antisettica

Publications (1)

Publication Number	Publication Date
GR3000878T3 true GR3000878T3 (en)	1991-11-15

Family

ID=11262040

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
GR90400682T GR3000878T3 (en)	1986-03-04	1990-09-27	Halogenides of the ester of 2,n,n,n-dimethyl-alkyl-amino-ethanol with substituted acetic acid and pharmaceutical compositions having antiinflammatory and antiseptic activities containing same

Country Status (6)

Country	Link
EP (1)	EP0237495B1 (el)
AT (1)	ATE56945T1 (el)
DE (1)	DE3765142D1 (el)
ES (1)	ES2017529B3 (el)
GR (1)	GR3000878T3 (el)
IT (1)	IT1208736B (el)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU1508988A (en) *	1987-04-27	1988-10-27	Syntex Pharmaceuticals International Ltd.	Omega-quaternary ammonium alkyl esters and thioesters of acidic nonsteroidal antiinflammatory drugs
IL89848A (en) *	1988-04-07	1997-08-14	Sepracor	Chiral ester derivatives
US5196568A (en) *	1988-04-07	1993-03-23	Sepracor, Inc.	Compounds useful in enzymatic resolution systems and their preparation
US20090221703A1 (en)	2006-07-09	2009-09-03	Chongxi Yu	High penetration composition and uses thereof
US20090238763A1 (en)	2006-07-09	2009-09-24	Chongxi Yu	High penetration compositions and uses thereof
HUE033687T2 (en) *	2006-07-18	2017-12-28	Techfields Biochem Co Ltd	Ibuprofen positively charged water soluble prodrugs with very fast skin penetration rates
CN103772259B (zh) *	2006-08-08	2016-08-31	于崇曦	具有快速皮肤穿透速度的带正电荷的芳基和杂芳基乙酸类前药
CN103772258B (zh) *	2006-08-08	2016-09-28	于崇曦	具有快速皮肤穿透速度的带正电荷的芳基和杂芳基乙酸类前药
WO2008149181A1 (en)	2007-06-04	2008-12-11	Techfields Inc	Pro-drugs of nsaias with very high skin and membranes penetration rates and their new medicinal uses
WO2010065936A1 (en)	2008-12-04	2010-06-10	Chongxi Yu	High penetration compositions and their applications

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4150137A (en) *	1975-12-24	1979-04-17	Hisamitsu Pharmaceutical Co. Inc.	Pyridylalkyl esters of 2-(p-isobutylphenyl)acetic acid and propionic acids and use
DE3023206A1 (de) *	1979-11-02	1982-01-14	Efeka Friedrich & Kaufmann GmbH & Co KG, 3000 Hannover	Indometacin-ester, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

1986
- 1986-03-04 IT IT8647711A patent/IT1208736B/it active
1987
- 1987-02-27 ES ES87830068T patent/ES2017529B3/es not_active Expired - Lifetime
- 1987-02-27 AT AT87830068T patent/ATE56945T1/de not_active IP Right Cessation
- 1987-02-27 EP EP87830068A patent/EP0237495B1/en not_active Expired - Lifetime
- 1987-02-27 DE DE8787830068T patent/DE3765142D1/de not_active Expired - Lifetime
1990
- 1990-09-27 GR GR90400682T patent/GR3000878T3/el unknown

Also Published As

Publication number	Publication date
ATE56945T1 (de)	1990-10-15
IT8647711A0 (it)	1986-03-04
EP0237495B1 (en)	1990-09-26
DE3765142D1 (de)	1990-10-31
IT1208736B (it)	1989-07-10
EP0237495A2 (en)	1987-09-16
EP0237495A3 (en)	1988-06-22
ES2017529B3 (es)	1991-02-16

Publication	Publication Date	Title
IE810463L (en)	1981-10-02	Octahydroindole carboxylic acids
DE19575041I2 (de)	2001-11-22	Substituierte Acyl-Derivate von 1, 2, 3, 4-Tetrahydro-6, 7-dimethoxy-3-isoquinolin-Carbonsaeure
NO173867C (no)	1994-02-16	Analogifremgangsmaate for fremstilling av terapeutisk aktive benzamider
AU600897B2 (en)	1990-08-30	N-acyl-alpha-amino-alpha-hydroxy acetic acid ester
FI862757A0 (fi)	1986-06-27	Pyridonkarbonsyraderivat och foerfarande foer framstaellning av dessa.
EP0237495A3 (en)	1988-06-22	Halogenides of the ester of 2,n,n,n-dimethyl-alkyl-amino-ethanol with substituted acetic acid and pharmaceutical compositions having antiinflammatory and antiseptic activities containing same
AU591640B2 (en)	1989-12-14	Quinolonecarboxylic acid derivatives
EP0332409A3 (en)	1991-01-23	Novel substituted naphthalene compounds and liquid crystal compositions containing same
DE68910211D1 (de)	1993-12-02	Estramustin-ester.
AU8295687A (en)	1988-06-23	Pyromellitic acid derivatives and their use as fuel additives
DE69415050D1 (de)	1999-01-21	Hexahydronaphthalenesterderivate, ihre Herstellung und ihre therapeutischen Anwendungen
GR3007465T3 (el)	1993-07-30
ES2068407T3 (es)	1995-04-16	Tratamiento de apneas durante el sueño con derivados de azapirona.
JPS6429367A (en)	1989-01-31	2-amino-5-hydroxy-4-pyrimidone
FI883507A0 (fi)	1988-07-26	Naftotiazepinderivat och deras framstaellning.
MX20084A (es)	1993-03-01	Derivados de 2 -carbapenem antibacterianos
EP0284069A3 (en)	1990-03-21	Benzopyranopyridineacetic acid ester compounds and their pharmaceutical uses