GR3007541T3 - - Google Patents

Info

Publication number: GR3007541T3
Authority: GR; Greece
Prior art keywords: factor viii; factor; phosphatidylserine; phosphatidylethanolamine; phosphatidylcholine
Prior art date: 1987-07-16

Application number

GR930400557T

Other languages

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-07-16

Filing date

1993-04-01

Publication date

1993-08-31

1993-04-01 Application filed filed Critical

1993-08-31 Publication of GR3007541T3 publication Critical patent/GR3007541T3/el

Links

TZCPCKNHXULUIY-RGULYWFUSA-N 1,2-distearoyl-sn-glycero-3-phosphoserine Chemical compound CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(=O)OC[C@H](N)C(O)=O)OC(=O)CCCCCCCCCCCCCCCCC TZCPCKNHXULUIY-RGULYWFUSA-N 0.000 abstract 3
108010054218 Factor VIII Proteins 0.000 abstract 3
102000001690 Factor VIII Human genes 0.000 abstract 3
ZWZWYGMENQVNFU-UHFFFAOYSA-N Glycerophosphorylserin Natural products OC(=O)C(N)COP(O)(=O)OCC(O)CO ZWZWYGMENQVNFU-UHFFFAOYSA-N 0.000 abstract 3
229960000301 factor viii Drugs 0.000 abstract 3
150000003904 phospholipids Chemical class 0.000 abstract 3
JZNWSCPGTDBMEW-UHFFFAOYSA-N Glycerophosphorylethanolamin Natural products NCCOP(O)(=O)OCC(O)CO JZNWSCPGTDBMEW-UHFFFAOYSA-N 0.000 abstract 2
WTJKGGKOPKCXLL-RRHRGVEJSA-N phosphatidylcholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCC=CCCCCCCCC WTJKGGKOPKCXLL-RRHRGVEJSA-N 0.000 abstract 2
150000008104 phosphatidylethanolamines Chemical class 0.000 abstract 2
238000001261 affinity purification Methods 0.000 abstract 1
230000004927 fusion Effects 0.000 abstract 1
108010047303 von Willebrand Factor Proteins 0.000 abstract 1
102100036537 von Willebrand factor Human genes 0.000 abstract 1
229960001134 von willebrand factor Drugs 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Biophysics (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Biochemistry (AREA)
Toxicology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Hematology (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

GR930400557T 1987-07-16 1993-04-01 GR3007541T3 (el)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/074,123 US4795806A (en)	1987-07-16	1987-07-16	Phospholipid affinity purification of Factor VIII:C

Publications (1)

Publication Number	Publication Date
GR3007541T3 true GR3007541T3 (el)	1993-08-31

Family

ID=22117866

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
GR930400557T GR3007541T3 (el)	1987-07-16	1993-04-01

Country Status (6)

Country	Link
US (1)	US4795806A (el)
EP (1)	EP0303064B1 (el)
AT (1)	ATE87632T1 (el)
DE (1)	DE3879803T2 (el)
ES (1)	ES2053631T3 (el)
GR (1)	GR3007541T3 (el)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU5930890A (en) *	1989-06-20	1991-01-08	Scripps Clinic And Research Foundation	The phospholipid binding domain of factor viii
US5110907A (en) *	1989-08-01	1992-05-05	Alpha Therapeutic Corporation	Factor viii complex purification using heparin affinity chromatography
AU7254894A (en) *	1993-07-23	1995-02-20	Baxter International Inc.	Activated human factor viii and method of preparation
US5576291A (en) *	1993-09-13	1996-11-19	Baxter International Inc.	Activated factor VIII as a therapeutic agent and method of treating factor VIII deficiency
DE4337573C1 (de) *	1993-11-04	1995-05-18	Octapharma Ag	Verfahren zur Herstellung einer virusinaktivierten Faktor VIII enthaltenden Fraktion mittels chromatographischer Methoden
EP0965597A4 (en) *	1996-12-27	2003-01-08	Mochida Pharm Co Ltd	CELL MEMBRANE EFFECTIVE DRUGS
CA2634663C (en)	1999-02-22	2009-08-25	University Of Connecticut	Novel albumin-free factor viii formulations
US8110218B2 (en) *	2000-11-30	2012-02-07	The Research Foundation Of State University Of New York	Compositions and methods for less immunogenic protein-lipid complexes
US7351688B2 (en) *	2003-02-05	2008-04-01	The Research Foundation Of State University Of New York	Compositions and methods for less immunogenic protein formulations
WO2005017526A1 (en) *	2003-08-05	2005-02-24	The Research Foundation Of State University Of New York	Reconstitution medium for protein and peptide formulations
WO2007002886A2 (en) *	2005-06-29	2007-01-04	The Research Foundation Of State University Of New York	Compositions and methods for less immunogenic pr0tein-lip1d complexes
EP1915176A4 (en) *	2005-07-15	2008-12-03	Univ Vermont	HIGHLY SENSITIVE IMMUNASSAYS AND ANTIBODIES FOR THE DETECTION OF BLOOD FACTOR VIII
WO2007021822A2 (en) *	2005-08-09	2007-02-22	The Research Foundation Of State Of University Of New York At Buffalo	Compositions and methods of preparation of liposomal microparticulate il-12
US7875288B2 (en) *	2006-03-30	2011-01-25	The Research Foundation Of State University Of New York	Method for treating blood coagulation disorders
JP5160534B2 (ja) *	2006-03-30	2013-03-13	ザリサーチファウンデイションオブステイトユニバーシティーオブニューヨーク	低免疫原性および長時間循環性タンパク質−脂質複合体の組成物
WO2008102469A1 (ja) *	2007-02-23	2008-08-28	Kwansei Gakuin Educational Foundation	蛋白質結晶化剤および蛋白質結晶化剤を用いた蛋白質結晶化方法
EP2385825B1 (en)	2008-11-07	2018-10-10	University of Connecticut	Factor viii formulations
EP2651433A1 (en) *	2010-12-16	2013-10-23	Novo Nordisk A/S	Aqueous factor viii solution

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4022758A (en) *	1973-06-19	1977-05-10	Ab Kabi	Isolation of coagulation factors I and VIII from biological material
DE3101752A1 (de) *	1981-01-21	1982-08-26	Behringwerke Ag, 3550 Marburg	"verfahren zur reinigung der blutgerinnungsfaktoren ii, vii, ix und/oder x und danach hergestellte praeparationen"
US4461833A (en) *	1982-06-23	1984-07-24	University Patents, Inc.	Chromatographically purifying proteolytic procoagulant enzyme from animal tissue extract
US4397841A (en) *	1982-06-28	1983-08-09	Monsanto Company	Production of blood coagulation factor VIII:C
US4508709A (en) *	1983-12-05	1985-04-02	Armour Pharmaceutical Company	Process for purifying factor VIII:C
GB8403473D0 (en) *	1984-02-09	1984-03-14	Special Trustees For St Thomas	Purification of factor viii
US4675385A (en) *	1985-03-27	1987-06-23	Alpha Therapeutic Corporation	Isolation of human plasma procoagulant protein factor VIII from biological factors

1987
- 1987-07-16 US US07/074,123 patent/US4795806A/en not_active Expired - Lifetime
1988
- 1988-07-14 AT AT88111301T patent/ATE87632T1/de not_active IP Right Cessation
- 1988-07-14 EP EP88111301A patent/EP0303064B1/en not_active Expired - Lifetime
- 1988-07-14 DE DE8888111301T patent/DE3879803T2/de not_active Expired - Fee Related
- 1988-07-14 ES ES88111301T patent/ES2053631T3/es not_active Expired - Lifetime
1993
- 1993-04-01 GR GR930400557T patent/GR3007541T3/el unknown

Also Published As

Publication number	Publication date
EP0303064A3 (en)	1990-05-16
EP0303064A2 (en)	1989-02-15
US4795806A (en)	1989-01-03
EP0303064B1 (en)	1993-03-31
ATE87632T1 (de)	1993-04-15
DE3879803D1 (de)	1993-05-06
ES2053631T3 (es)	1994-08-01
DE3879803T2 (de)	1993-07-08

Publication	Publication Date	Title
EP0303064A3 (en)	1990-05-16	Phospholipid affinity purification of factor viii:c
AU6733487A (en)	1987-06-02	Mammalian interleukin-4
AU563925B2 (en)	1987-07-30	Removal of lipid containing virus in blood
AU573523B2 (en)	1988-06-16	Functional human urokinase proteins
EP1245678A3 (en)	2002-10-09	Recombinant proteins of viruses associated with lymphadenopathy syndrome and/or acquired immune deficiency syndrome
AU580348B2 (en)	1989-01-12	A process for the cleavage of peptides and proteins at the methionyl bond
CA2097199A1 (en)	1993-04-05	Preparation of prothrombin time reagents from recombinant human tissue factor and purified natural and synthetic phospholipids
FI91160B (fi)	1994-02-15	Menetelmä modifioidun ihmisen t-PA-proteiinin valmistamiseksi
EP0344459A3 (en)	1989-12-27	Expression of human serum albumin in metholotrophic yeasts
AU3473489A (en)	1989-11-16	Expression of hepatisis b s and pres2proteins in methylotrophic yeasts
AU5207196A (en)	1996-11-28	Production of recombinant factor VIII in the presence of lipsome-like substances of mixed composition
AU7423391A (en)	1991-10-17	Dna constructs for the expression of proteins in the mammary gland of transgenetic mammals
EP0395653A4 (en)	1991-12-04	Synovial phospholipases
AU5632186A (en)	1986-11-06	Improvements in or relating to decorative fabrics
AU6979287A (en)	1988-08-11	Fusion proteins
AU4043489A (en)	1990-03-05	Improvements in or relating to reducing the strength of electro-magnetic fields
AU1321988A (en)	1988-09-22	The cloning of malaria-specific dna sequences: isolation of the gene for the 140 kd protein
AU1294888A (en)	1988-08-24	Recombinant alveolar surfactant protein
SU1538846A1 (ru)	1995-02-27	Лазерный материал
JPS6458681A (en)	1989-03-06	Buffer material for packing
AU4320389A (en)	1990-04-02	Improvements in or relating to ceiling suspension arrangements