GR3020083T3 - 23-oxa derivatives of d-series vitamins, method of preparing them, pharmaceutical preparations containing them, and the use of such preparations as drugs. - Google Patents

23-oxa derivatives of d-series vitamins, method of preparing them, pharmaceutical preparations containing them, and the use of such preparations as drugs.

Info

Publication number: GR3020083T3
Authority: GR; Greece
Prior art keywords: pct; drugs; preparing; preparations; oxa
Prior art date: 1991-01-19

Application number

GR960401330T

Other languages

English (en)

Inventor

Guenter Neef

Andreas Steinmeyer

Gerald Kirsch

Katica Schwarz

Martin Haberey

Ruth Thieroff-Ekerdt

Petra Rach

Original Assignee

Schering Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-01-19

Filing date

1996-05-30

Publication date

1996-08-31

1996-05-30 Application filed by Schering Ag filed Critical Schering Ag

1996-08-31 Publication of GR3020083T3 publication Critical patent/GR3020083T3/el

Links

238000000034 method Methods 0.000 title abstract 2
229940079593 drug Drugs 0.000 title 1
239000003814 drug Substances 0.000 title 1
239000000825 pharmaceutical preparation Substances 0.000 title 1
238000002360 preparation method Methods 0.000 title 1
229940088594 vitamin Drugs 0.000 title 1
229930003231 vitamin Natural products 0.000 title 1
235000013343 vitamin Nutrition 0.000 title 1
239000011782 vitamin Substances 0.000 title 1
125000004432 carbon atom Chemical group C* 0.000 abstract 2
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
229930003316 Vitamin D Natural products 0.000 abstract 1
QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 abstract 1
125000002252 acyl group Chemical group 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
125000002947 alkylene group Chemical group 0.000 abstract 1
230000024245 cell differentiation Effects 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
230000002401 inhibitory effect Effects 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
239000008177 pharmaceutical agent Substances 0.000 abstract 1
230000035755 proliferation Effects 0.000 abstract 1
125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
235000019166 vitamin D Nutrition 0.000 abstract 1
239000011710 vitamin D Substances 0.000 abstract 1
150000003710 vitamin D derivatives Chemical class 0.000 abstract 1
229940046008 vitamin d Drugs 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Dermatology (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

GR960401330T 1991-01-19 1996-05-30 23-oxa derivatives of d-series vitamins, method of preparing them, pharmaceutical preparations containing them, and the use of such preparations as drugs. GR3020083T3 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE4101953A DE4101953A1 (de)	1991-01-19	1991-01-19	23-oxa-derivate in der vitamin-d-reihe, verfahren zu ihrer herstellung diese derivate enthaltende pharmazeutische praeparate sowie deren verwendung als arzneimittel
PCT/EP1992/000123 WO1992012963A1 (de)	1991-01-19	1992-01-20	23-oxa-derivate in der vitamin-d-reihe, verfahren zu ihrer herstellung, diese derivate enthaltende pharmazeutische präparate sowie deren verwendung als arzneimittel

Publications (1)

Publication Number	Publication Date
GR3020083T3 true GR3020083T3 (en)	1996-08-31

Family

ID=6423566

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
GR960401330T GR3020083T3 (en)	1991-01-19	1996-05-30	23-oxa derivatives of d-series vitamins, method of preparing them, pharmaceutical preparations containing them, and the use of such preparations as drugs.

Country Status (11)

Country	Link
US (1)	US5411949A (el)
EP (1)	EP0639179B1 (el)
JP (1)	JP3207423B2 (el)
AT (1)	ATE138647T1 (el)
DE (2)	DE4101953A1 (el)
DK (1)	DK0639179T3 (el)
ES (1)	ES2089497T3 (el)
GR (1)	GR3020083T3 (el)
IE (1)	IE74251B1 (el)
PT (1)	PT100035B (el)
WO (1)	WO1992012963A1 (el)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PT665221E (pt) *	1992-10-16	2000-06-30	Chugai Pharmaceutical Co Ltd	Derivado da vitamina d e processo para a sua producao
TW267161B (el) *	1992-11-20	1996-01-01	Hoffmann La Roche
US20040167106A1 (en) *	1993-06-04	2004-08-26	Rodriguez Gustavo C.	Prevention of ovarian cancer by administration of a Vitamin D compound
US6407082B1 (en) *	1996-09-13	2002-06-18	New Life Pharmaceuticals Inc.	Prevention of ovarian cancer by administration of a vitamin D compound
CA2239617A1 (en)	1995-12-29	1997-07-10	A And D Assay, Incorporated	Labeled vitamin d compounds and the use thereof
US6028064A (en)	1996-09-13	2000-02-22	New Life Pharmaceuticals Inc.	Prevention of ovarian cancer by administration of progestin products
US6765002B2 (en)	2000-03-21	2004-07-20	Gustavo Rodriguez	Prevention of ovarian cancer by administration of products that induce transforming growth factor-β and/or apoptosis in the ovarian epithelium
US6511970B1 (en)	1996-09-13	2003-01-28	New Life Pharmaceuticals Inc.	Prevention of ovarian cancer by administration of products that induce transforming growth factor-beta and/or apoptosis in the ovarian epithelium
US6034074A (en) *	1996-09-13	2000-03-07	New Life Pharmaceuticals Inc.	Prevention of ovarian cancer by administration of a Vitamin D compound
US6087350A (en) *	1997-08-29	2000-07-11	University Of Pittsburgh Of The Commonwealth System Of Higher Education	Use of pretreatment chemicals to enhance efficacy of cytotoxic agents
WO1999049870A1 (en)	1998-03-27	1999-10-07	Oregon Health Sciences University	Vitamin d and its analogs in the treatment of tumors and other hyperproliferative disorders
AU768037B2 (en) *	1999-04-23	2003-11-27	Leo Pharmaceutical Products Ltd. A/S (Lovens Kemiske Fabrik Produktionsaktieselskab)	Vitamin D analogues and their pharmaceutical use
US20010044431A1 (en) *	2000-03-21	2001-11-22	Rodriguez Gustavo C.	Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium
WO2004054968A2 (en) *	2002-12-18	2004-07-01	Johns Hopkins University	25-so2-substituted analogs of 1alpha, 25-dihydroxyvitamin d3 (calcitriol)
AU2006245283B2 (en)	2005-05-10	2012-11-01	Dermipsor Ltd.	Compositions and methods for treating hyperproliferative epidermal diseases
WO2008024485A2 (en)	2006-08-25	2008-02-28	Cougar Biotechnology, Inc.	Methods for treating cancer comprising the administration of a vitamin d compound and an additional therapeutic agent
US20080051375A1 (en) *	2006-08-25	2008-02-28	Auerbach Alan H	Methods for treating cancer comprising the administration of a vitamin d compound and an additional therapeutic agent, and compositions containing the same
US20080051380A1 (en) *	2006-08-25	2008-02-28	Auerbach Alan H	Methods and compositions for treating cancer
US20090124587A1 (en) *	2007-07-12	2009-05-14	Auerbach Alan H	METHODS FOR TREATING CANCER USING 17alpha-HYDROXYLASE/C17,20-LYASE INHIBITORS
AU2010208323B2 (en)	2009-01-27	2016-03-10	Berg Llc	Vitamin D3 and analogs thereof for alleviating side effects associated with chemotherapy
EP2464357B1 (en)	2009-08-14	2019-05-22	Berg LLC	Vitamin d3 and analogs thereof for treating alopecia
FI124171B (en)	2012-05-29	2014-04-15	Matti Mällinen	Biofilter
US20190183908A1 (en)	2016-05-13	2019-06-20	Case Western Reserve University	Autophagy activators for treating or preventing skin injury
CN119606965A (zh)	2016-07-29	2025-03-14	詹森药业有限公司	治疗前列腺癌的方法
US11903952B2 (en)	2020-05-27	2024-02-20	Northwestern University	Vitamin D as an immune modulator to prevent immune-related complication from COVID-19 infection

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL67153A (en) *	1981-11-02	1986-12-31	Res Inst Medicine Chem	Intermediates in the production of vitamin d analogues and method for their production
CA1332841C (en) *	1984-11-27	1994-11-01	Noboru Kubodera	Vitamin d derivatives and process for producing the same
GB8904153D0 (en) *	1989-02-23	1989-04-05	Leo Pharm Prod Ltd	Chemical compounds
GB9007236D0 (en) *	1990-03-30	1990-05-30	Leo Pharm Prod Ltd	Chemical compounds

1991
- 1991-01-19 DE DE4101953A patent/DE4101953A1/de not_active Ceased
1992
- 1992-01-17 PT PT100035A patent/PT100035B/pt not_active IP Right Cessation
- 1992-01-20 EP EP92903336A patent/EP0639179B1/de not_active Expired - Lifetime
- 1992-01-20 IE IE920156A patent/IE74251B1/en not_active IP Right Cessation
- 1992-01-20 WO PCT/EP1992/000123 patent/WO1992012963A1/de not_active Ceased
- 1992-01-20 AT AT92903336T patent/ATE138647T1/de not_active IP Right Cessation
- 1992-01-20 US US08/090,201 patent/US5411949A/en not_active Expired - Fee Related
- 1992-01-20 DK DK92903336.3T patent/DK0639179T3/da active
- 1992-01-20 ES ES92903336T patent/ES2089497T3/es not_active Expired - Lifetime
- 1992-01-20 DE DE59206439T patent/DE59206439D1/de not_active Expired - Lifetime
- 1992-01-20 JP JP50348292A patent/JP3207423B2/ja not_active Expired - Fee Related
1996
- 1996-05-30 GR GR960401330T patent/GR3020083T3/el unknown

Also Published As

Publication number	Publication date
PT100035A (pt)	1993-05-31
IE920156A1 (en)	1992-07-29
EP0639179B1 (de)	1996-05-29
JP3207423B2 (ja)	2001-09-10
EP0639179A1 (de)	1995-02-22
IE74251B1 (en)	1997-07-16
WO1992012963A1 (de)	1992-08-06
JPH06506915A (ja)	1994-08-04
DK0639179T3 (da)	1996-10-14
ES2089497T3 (es)	1996-10-01
ATE138647T1 (de)	1996-06-15
DE4101953A1 (de)	1992-07-23
US5411949A (en)	1995-05-02
PT100035B (pt)	1999-08-31
DE59206439D1 (de)	1996-07-04
EP0639179A4 (de)	1993-09-17

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