GR3022353T3 - Biguanide derivatives, manufacturing method thereof, and disinfectants containing the derivatives - Google Patents

Biguanide derivatives, manufacturing method thereof, and disinfectants containing the derivatives

Info

Publication number
GR3022353T3
GR3022353T3 GR960401488T GR960401488T GR3022353T3 GR 3022353 T3 GR3022353 T3 GR 3022353T3 GR 960401488 T GR960401488 T GR 960401488T GR 960401488 T GR960401488 T GR 960401488T GR 3022353 T3 GR3022353 T3 GR 3022353T3
Authority
GR
Greece
Prior art keywords
derivatives
manufacturing
biguanide
disinfectants containing
chem
Prior art date
Application number
GR960401488T
Other languages
English (en)
Inventor
Hiroshi Ishikawa
Koichi Yasumura
Hidetsugu Tsubouchi
Yukio Higuchi
Hisashi Tamaoka
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP3073202A external-priority patent/JPH04308562A/ja
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of GR3022353T3 publication Critical patent/GR3022353T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/24—Y being a hetero atom
    • C07C279/26—X and Y being nitrogen atoms, i.e. biguanides
    • C07C279/265—X and Y being nitrogen atoms, i.e. biguanides containing two or more biguanide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/24—Y being a hetero atom
    • C07C279/26—X and Y being nitrogen atoms, i.e. biguanides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
GR960401488T 1991-04-05 1997-01-23 Biguanide derivatives, manufacturing method thereof, and disinfectants containing the derivatives GR3022353T3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP3073202A JPH04308562A (ja) 1991-04-05 1991-04-05 ビスビグアナイド誘導体とこの誘導体を含有した消毒薬
JP14764491 1991-06-19
JP22430691 1991-09-04

Publications (1)

Publication Number Publication Date
GR3022353T3 true GR3022353T3 (en) 1997-04-30

Family

ID=27301157

Family Applications (1)

Application Number Title Priority Date Filing Date
GR960401488T GR3022353T3 (en) 1991-04-05 1997-01-23 Biguanide derivatives, manufacturing method thereof, and disinfectants containing the derivatives

Country Status (13)

Country Link
US (1) US5376686A (el)
EP (1) EP0507317B1 (el)
KR (1) KR100195548B1 (el)
CN (1) CN1038248C (el)
AT (1) ATE147725T1 (el)
AU (1) AU651184B2 (el)
CA (1) CA2064664C (el)
DE (1) DE69216674T2 (el)
DK (1) DK0507317T3 (el)
ES (1) ES2099176T3 (el)
GR (1) GR3022353T3 (el)
HK (1) HK1007310A1 (el)
MX (1) MX9201564A (el)

Families Citing this family (25)

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GB9506841D0 (en) * 1995-04-03 1995-05-24 Unilever Plc Deodorant compositions
US6488942B1 (en) * 1997-10-18 2002-12-03 Ddg Dental Devices Gmbh Disinfecting agent
ZA9811445B (en) * 1997-12-19 1999-08-16 Alcon Lab Inc Aminobiguanides and the use thereof to disinfect contact lenses and preserve pharmaceutical compositions.
WO2003024407A2 (en) * 2001-09-21 2003-03-27 Message Pharmaceuticals, Inc. Inhibitors of rnase p proteins as antibacterial compounds
US7256218B2 (en) 2002-11-22 2007-08-14 Jacobus Pharmaceutical Company, Inc. Biguanide and dihydrotriazine derivatives
PL1634589T3 (pl) * 2003-05-28 2011-07-29 Otsuka Pharma Co Ltd Wodny roztwór olaneksydyny, sposób jego wytwarzania i środek dezynfekcyjny
TW200509893A (en) * 2003-05-28 2005-03-16 Otsuka Pharma Co Ltd A composition for sterilizing and/ or disinfecting
EP2409692A1 (en) * 2004-11-17 2012-01-25 Otsuka America Pharmaceutical, Inc. Fluid application device and method
CA2661272C (en) * 2006-08-30 2014-03-18 Otsuka Pharmaceutical Co., Ltd. Process for producing 1-(3,4-dichlorobenzyl)-5-octylbiguanide or a salt thereof
MX2010012488A (es) * 2008-05-19 2011-02-23 Otsuka America Pharmaceutical Inc Metodo y aparato para preparar una solucion de un material sensible al corte.
KR101083300B1 (ko) * 2008-10-13 2011-11-14 한국화학연구원 Ｎ1-벤조［1,3］다이옥솔-5-일메틸-ｎ2-치환된 바이구아나이드 유도체, 이의 제조방법 및 이를 유효성분으로 함유하는 약학 조성물
TWI556845B (zh) 2008-12-30 2016-11-11 大塚美國製藥股份有限公司 施加流體的裝置和方法
TWI524875B (zh) 2008-12-30 2016-03-11 大塚製藥工場股份有限公司 用於施加流體的施加器裝置和系統、和設置在施加器裝置中的流體盛裝容器
EP2522654A2 (en) 2010-01-06 2012-11-14 HanAll Biopharma Co., Ltd. Biguanide derivative, preparation method thereof, and pharmaceutical composition containing same as an active ingredient
US8933055B2 (en) * 2010-09-22 2015-01-13 Ecolab Usa Inc. Antimicrobial compositions containing cationic active ingredients and quaternary sugar derived surfactants
CN102584638B (zh) * 2012-01-19 2014-06-11 山东省农业科学院中心实验室 一种n-(取代苯基) 六亚甲基双胍盐酸盐及其合成方法
CN102993057B (zh) * 2012-12-04 2014-09-17 甘肃省化工研究院 1,6-双氰基胍基己烷的合成方法
US9956153B2 (en) 2014-08-01 2018-05-01 Ecolab Usa Inc. Antimicrobial foaming compositions containing cationic active ingredients
KR102216701B1 (ko) 2014-11-20 2021-02-18 이뮤노메트테라퓨틱스 인코포레이티드 바이구아나이드 화합물 및 이의 용도
US10494350B2 (en) * 2015-09-11 2019-12-03 Bayer Cropscience Aktiengesellschaft Process for producing biguanidine salts and s-triazines
CN110494132A (zh) * 2017-04-19 2019-11-22 株式会社大塚制药工场 抗炎剂
CN107646862B (zh) * 2017-10-27 2021-05-07 江苏食品药品职业技术学院 基于抗坏血酸的奥兰西丁水溶液及其制备方法和应用
CN107668062B (zh) * 2017-10-27 2021-03-09 金英花 基于透明质酸的奥兰西丁水溶液及其制备方法和应用
ES2944838T3 (es) * 2018-07-18 2023-06-26 Otsuka Pharma Factory Inc Composición desinfectante
CN110615886A (zh) * 2019-09-05 2019-12-27 哈尔滨工程大学 一种双胍衍生物抗菌型环氧树脂固化剂及其制备方法

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US403243A (en) * 1889-05-14 Vehicle-spring
GB577843A (en) * 1944-05-10 1946-06-03 Francis Henry Swinden Curd Biguanide derivatives
US2467371A (en) * 1944-05-10 1949-04-19 Ici Ltd Biguanide derivatives
US2455896A (en) * 1945-10-12 1948-12-07 American Cyanamid Co 1-aryl, 5-alkyl, biguanides
FR1015134A (fr) * 1948-01-28 1952-08-27 Ici Ltd Fabrication de dérivés de la biguanide
US2544827A (en) * 1948-08-20 1951-03-13 Ici Ltd Manufacture of biguanide derivatives
BE612529A (el) * 1961-01-13
BE612641A (el) * 1961-01-18
BR6568736D0 (pt) * 1964-04-09 1973-08-14 Drug Inc Sterling Processo para preparar uma bisguanida
US3403243A (en) * 1965-05-27 1968-09-24 Tasope Ltd Radiant burn-in unit for photoengraving plates
US3366650A (en) * 1965-10-07 1968-01-30 Squibb & Sons Inc Tetra-and penta-fluoro-phenyl- and phenylalkyl-biguanides and salts thereof
DE2009738A1 (de) * 1970-03-03 1971-09-16 Farbenfabriken Bayer Aktiengesell schaft, 5090 Leverkusen Substituierte Biguanide mit antihyper glykamischer Wirkung
DE2009743A1 (de) * 1970-03-03 1971-09-16 Farbenfabriken Bayer Ag, 5090 Leverkusen Substituierte Biguanide mit antihyperglykämischer Wirkung
US3879541A (en) * 1970-03-03 1975-04-22 Bayer Ag Antihyperglycemic methods and compositions
US3996232A (en) * 1970-11-23 1976-12-07 William H. Rorer, Inc. 1,5-Disubstituted biguanides
US3891705A (en) * 1971-10-14 1975-06-24 Rorer Inc William H S-triazines
US4183958A (en) * 1978-09-26 1980-01-15 Gaf Corporation Fungicidal 1-(alkoxyphenyl)-5-(substituted phenyl) biguanide compounds
GB8327561D0 (en) * 1983-10-14 1983-11-16 Ici Plc Contraceptive methods
US4567174A (en) * 1984-05-07 1986-01-28 Imperial Chemical Industries Plc Bis(1-substituted biguanide) derivatives

Also Published As

Publication number Publication date
CA2064664A1 (en) 1992-10-06
AU651184B2 (en) 1994-07-14
KR100195548B1 (ko) 1999-06-15
CN1065453A (zh) 1992-10-21
EP0507317A3 (en) 1993-02-24
DK0507317T3 (da) 1997-02-03
DE69216674T2 (de) 1997-05-28
ES2099176T3 (es) 1997-05-16
MX9201564A (es) 1994-03-31
KR920019731A (ko) 1992-11-19
CA2064664C (en) 2000-01-11
AU1401692A (en) 1992-10-08
HK1007310A1 (en) 1999-04-09
DE69216674D1 (de) 1997-02-27
EP0507317A2 (en) 1992-10-07
ATE147725T1 (de) 1997-02-15
EP0507317B1 (en) 1997-01-15
US5376686A (en) 1994-12-27
CN1038248C (zh) 1998-05-06

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