GR3033095T3 - Anti-gp39 antibodies and uses therefor - Google Patents

Anti-gp39 antibodies and uses therefor

Info

Publication number
GR3033095T3
GR3033095T3 GR20000400784T GR20000400784T GR3033095T3 GR 3033095 T3 GR3033095 T3 GR 3033095T3 GR 20000400784 T GR20000400784 T GR 20000400784T GR 20000400784 T GR20000400784 T GR 20000400784T GR 3033095 T3 GR3033095 T3 GR 3033095T3
Authority
GR
Greece
Prior art keywords
antibodies
uses therefor
therefor
Prior art date
Application number
GR20000400784T
Other languages
English (en)
Inventor
Randolph J Noelle
Teresa M Foy
Alejandro Aruffo
Jeffrey A Ledbetter
Original Assignee
Dartmouth College
Bristol Myers Squibb Pharmaceu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26814047&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GR3033095(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US08/232,929 external-priority patent/US5869049A/en
Application filed by Dartmouth College, Bristol Myers Squibb Pharmaceu filed Critical Dartmouth College
Publication of GR3033095T3 publication Critical patent/GR3033095T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2875—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Transplantation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
GR20000400784T 1993-09-02 2000-03-29 Anti-gp39 antibodies and uses therefor GR3033095T3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11625593A 1993-09-02 1993-09-02
US08/232,929 US5869049A (en) 1993-09-02 1994-04-25 Methods of inducing T cell unresponsiveness to bone marrow with gp39 antagonists
PCT/US1994/009871 WO1995006666A1 (en) 1993-09-02 1994-09-02 Anti-gp39 antibodies and uses therefor

Publications (1)

Publication Number Publication Date
GR3033095T3 true GR3033095T3 (en) 2000-08-31

Family

ID=26814047

Family Applications (2)

Application Number Title Priority Date Filing Date
GR980401834T GR3027658T3 (en) 1993-09-02 1998-08-14 Methods for inducing antigen-specific t cell tolerance
GR20000400784T GR3033095T3 (en) 1993-09-02 2000-03-29 Anti-gp39 antibodies and uses therefor

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GR980401834T GR3027658T3 (en) 1993-09-02 1998-08-14 Methods for inducing antigen-specific t cell tolerance

Country Status (17)

Country Link
US (5) US5747037A (el)
EP (2) EP0721346B1 (el)
JP (3) JP3007977B2 (el)
CN (2) CN100341896C (el)
AT (2) ATE167062T1 (el)
AU (2) AU696235B2 (el)
DE (2) DE69411025T2 (el)
DK (2) DK0721346T3 (el)
ES (2) ES2143553T3 (el)
FI (2) FI105528B (el)
GR (2) GR3027658T3 (el)
HU (2) HU220296B (el)
IL (1) IL110855A (el)
NO (2) NO321036B1 (el)
NZ (3) NZ273221A (el)
PT (1) PT721469E (el)
WO (2) WO1995006666A1 (el)

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ES2143553T3 (es) * 1993-09-02 2000-05-16 Dartmouth College Anticuerpos anti-gp39 y sus utilizaciones.
US5683693A (en) * 1994-04-25 1997-11-04 Trustees Of Dartmouth College Method for inducing T cell unresponsiveness to a tissue or organ graft with anti-CD40 ligand antibody or soluble CD40
US5876950A (en) * 1995-01-26 1999-03-02 Bristol-Myers Squibb Company Monoclonal antibodies specific for different epitopes of human GP39 and methods for their use in diagnosis and therapy
JPH08239324A (ja) * 1995-03-03 1996-09-17 Fusanori Hamashima 免疫抑制剤
US7175847B1 (en) 1995-06-07 2007-02-13 Biogen Idec Inc. Treating intestinal inflammation with anti-CD80 antibodies that do not inhibit CD80 binding to CTLA-4
US5833987A (en) * 1995-06-07 1998-11-10 Trustees Of Dartmouth College Treatment of T cell mediated autoimmune disorders
US6113898A (en) 1995-06-07 2000-09-05 Idec Pharmaceuticals Corporation Human B7.1-specific primatized antibodies and transfectomas expressing said antibodies
US7153508B2 (en) 1995-06-07 2006-12-26 Biogen Idec Inc. Treatment of B cell lymphoma using anti-CD80 antibodies that do not inhibit the binding of CD80 to CTLA-4
US6440418B1 (en) * 1995-11-07 2002-08-27 Idec Pharmaceuticals Corporation Methods of treating autoimmune diseases with gp39-specific antibodies
US6001358A (en) 1995-11-07 1999-12-14 Idec Pharmaceuticals Corporation Humanized antibodies to human gp39, compositions containing thereof
US6340459B1 (en) 1995-12-01 2002-01-22 The Trustees Of Columbia University In The City Of New York Therapeutic applications for the anti-T-BAM (CD40-L) monoclonal antibody 5C8 in the treatment of reperfusion injury in non-transplant recipients
EP0892643B2 (en) * 1996-03-20 2009-09-02 Bristol-Myers Squibb Company Methods for inhibiting an immune response by blocking the gp39/cd40 and ctla4/cd28/b7 pathways and compositions for use therewith
DE19634159C1 (de) * 1996-08-23 1997-09-25 Gsf Forschungszentrum Umwelt Induktion einer Tumorimmunität durch Injektion von Hybridzellen
WO1998008541A1 (en) * 1996-08-30 1998-03-05 Genzyme Corporation Inhibition of primary and/or secondary immune response to repeat adenoviral vector administration using cd40l specific antibodies
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Also Published As

Publication number Publication date
HUT74250A (en) 1996-11-28
PT721469E (pt) 2000-04-28
NO960861D0 (no) 1996-03-01
CN1134113A (zh) 1996-10-23
JP2991499B2 (ja) 1999-12-20
EP0721469B1 (en) 2000-01-05
EP0721346A1 (en) 1996-07-17
US20060222649A1 (en) 2006-10-05
NO960861L (no) 1996-04-30
FI960980A7 (fi) 1996-04-30
DE69422523D1 (de) 2000-02-10
ATE167062T1 (de) 1998-06-15
FI105528B (fi) 2000-09-15
DE69422523T2 (de) 2000-10-12
US5747037A (en) 1998-05-05
HU9600522D0 (en) 1996-04-29
US20020187135A1 (en) 2002-12-12
AU678532B2 (en) 1997-05-29
DE69411025D1 (de) 1998-07-16
JPH09502186A (ja) 1997-03-04
IL110855A (en) 1999-04-11
CN100341896C (zh) 2007-10-10
DE69411025T2 (de) 1999-01-07
HU220296B (hu) 2001-11-28
ES2143553T3 (es) 2000-05-16
NZ549136A (en) 2008-02-29
NO321098B1 (no) 2006-03-20
NO960862L (no) 1996-04-30
CN1149299A (zh) 1997-05-07
AU7644594A (en) 1995-03-22
EP0721469A1 (en) 1996-07-17
US5876718A (en) 1999-03-02
GR3027658T3 (en) 1998-11-30
FI960980A0 (fi) 1996-03-01
EP0721346B1 (en) 1998-06-10
NZ273207A (en) 1997-09-22
DK0721346T3 (da) 1999-03-22
NO321036B1 (no) 2006-03-06
FI960978L (fi) 1996-04-29
AU707110B2 (en) 1999-07-01
US7722874B2 (en) 2010-05-25
NZ273221A (en) 2001-09-28
ATE188487T1 (de) 2000-01-15
ES2120067T3 (es) 1998-10-16
AU7642994A (en) 1995-03-22
IL110855A0 (en) 1994-11-28
FI106306B (fi) 2001-01-15
AU696235B2 (en) 1998-09-03
AU3518397A (en) 1997-10-30
JP3098739B2 (ja) 2000-10-16
FI960978A0 (fi) 1996-03-01
HUT74246A (en) 1996-11-28
WO1995006666A1 (en) 1995-03-09
JPH11189543A (ja) 1999-07-13
HU218610B (hu) 2000-10-28
DK0721469T3 (da) 2000-05-01
US6312692B1 (en) 2001-11-06
JPH09502096A (ja) 1997-03-04
CN1127351C (zh) 2003-11-12
WO1995006481A1 (en) 1995-03-09
JP3007977B2 (ja) 2000-02-14
NO960862D0 (no) 1996-03-01
HU9600521D0 (en) 1996-04-29

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