GR3036666T3 - -g(D)5-ANDROSTENES USEFUL FOR PROMOTING WEIGHT MAINTENANCE OR WEIGHT LOSS AND TREATMENT PROCESS. - Google Patents

-g(D)5-ANDROSTENES USEFUL FOR PROMOTING WEIGHT MAINTENANCE OR WEIGHT LOSS AND TREATMENT PROCESS.

Info

Publication number: GR3036666T3
Authority: GR; Greece
Prior art keywords: beta; delta; androstene; alpha; androstenes
Prior art date: 1993-09-02

Application number

GR20010401526T

Other languages

English (en)

Inventor

Henry A Lardy

Ieva L Reich

Wei Yong

Original Assignee

Humanetics Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-09-02

Filing date

2001-09-18

Publication date

2001-12-31

2001-09-18 Application filed by Humanetics Corp filed Critical Humanetics Corp

2001-12-31 Publication of GR3036666T3 publication Critical patent/GR3036666T3/el

Links

238000000034 method Methods 0.000 title abstract 2
230000001737 promoting effect Effects 0.000 title abstract 2
238000012423 maintenance Methods 0.000 title 1
230000004580 weight loss Effects 0.000 title 1
OSVMTWJCGUFAOD-KZQROQTASA-N formestane Chemical compound O=C1CC[C@]2(C)[C@H]3CC[C@](C)(C(CC4)=O)[C@@H]4[C@@H]3CCC2=C1O OSVMTWJCGUFAOD-KZQROQTASA-N 0.000 abstract 3
SBNLPRGISFUZQE-VMXHOPILSA-N (8s,9s,10r,13s,14s)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1h-cyclopenta[a]phenanthrene Chemical class C1C=C2CCCC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CCC[C@@]1(C)CC2 SBNLPRGISFUZQE-VMXHOPILSA-N 0.000 abstract 2
238000004260 weight control Methods 0.000 abstract 2
OEVZKEVBDIDVOI-FMKNUBLKSA-N androst-5-ene-3beta,7alpha,17beta-triol Chemical compound C1[C@@H](O)CC[C@]2(C)[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3[C@H](O)C=C21 OEVZKEVBDIDVOI-FMKNUBLKSA-N 0.000 abstract 1
230000036528 appetite Effects 0.000 abstract 1
235000019789 appetite Nutrition 0.000 abstract 1
230000004071 biological effect Effects 0.000 abstract 1
230000015572 biosynthetic process Effects 0.000 abstract 1
239000003163 gonadal steroid hormone Substances 0.000 abstract 1
230000007062 hydrolysis Effects 0.000 abstract 1
238000006460 hydrolysis reaction Methods 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
230000001939 inductive effect Effects 0.000 abstract 1
125000000468 ketone group Chemical group 0.000 abstract 1
238000003786 synthesis reaction Methods 0.000 abstract 1
230000001225 therapeutic effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0018—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
- C07J1/0022—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Diabetes (AREA)
Bioinformatics & Cheminformatics (AREA)
Child & Adolescent Psychology (AREA)
Endocrinology (AREA)
Hematology (AREA)
Obesity (AREA)
Epidemiology (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pretreatment Of Seeds And Plants (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Diaphragms For Electromechanical Transducers (AREA)

GR20010401526T 1993-09-02 2001-09-18 -g(D)5-ANDROSTENES USEFUL FOR PROMOTING WEIGHT MAINTENANCE OR WEIGHT LOSS AND TREATMENT PROCESS. GR3036666T3 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US12315193A	1993-09-02	1993-09-02
PCT/US1994/009852 WO1995006472A1 (en)	1993-09-02	1994-09-01	Δ5-androstenes useful for promoting weight maintenance or weight loss and treatment process

Publications (1)

Publication Number	Publication Date
GR3036666T3 true GR3036666T3 (en)	2001-12-31

Family

ID=22406999

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
GR20010401526T GR3036666T3 (en)	1993-09-02	2001-09-18	-g(D)5-ANDROSTENES USEFUL FOR PROMOTING WEIGHT MAINTENANCE OR WEIGHT LOSS AND TREATMENT PROCESS.

Country Status (11)

Country	Link
EP (1)	EP0666746B1 (el)
JP (1)	JP3143749B2 (el)
AT (1)	ATE202707T1 (el)
AU (1)	AU7679494A (el)
CA (1)	CA2148373A1 (el)
DE (1)	DE69427634T2 (el)
DK (1)	DK0666746T3 (el)
ES (1)	ES2160128T3 (el)
GR (1)	GR3036666T3 (el)
PT (1)	PT666746E (el)
WO (1)	WO1995006472A1 (el)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE69737791D1 (de)	1996-04-09	2007-07-19	Univ Edinburgh	Verwendung von 7-alpha-substituierten steroiden zur behandlung von neuropsychiatrischen erkrankungen
US6153606A (en) *	1998-10-16	2000-11-28	Humanetics Corporation	Memory enhancement by the administration of Δ5-androstene-3β-ol-7,17-dione and 3β esters thereof
US6667299B1 (en)	2000-03-16	2003-12-23	Hollis-Eden Pharmaceuticals, Inc.	Pharmaceutical compositions and treatment methods
JP2005508178A (ja) *	2001-11-08	2005-03-31	デヴェロゲンアクチエンゲゼルシャフトフュアエントヴィックルングスビオローギッシェフォルシュング	エネルギー恒常性の調節に関与するＭｅｎタンパク質、ＧＳＴ２、Ｒａｂ−ＲＰ１、Ｃｓｐ、Ｆ−ボックスタンパク質Ｌｉｌｉｎａ／ＦＢＬ７、ＡＢＣ５０、コロニン、Ｓｅｃ６１α、またはＶｈａＰＰＡ１−１、または相同性タンパク質

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5028631A (en) *	1987-11-25	1991-07-02	Schwartz Arthur G	Homoandrostan-17-one and homoandrosten-17-ones
AU647528B2 (en) *	1990-08-29	1994-03-24	Humanetics Corporation	Treatment process for promoting weight loss employing a substituted delta5-androstene

1994
- 1994-09-01 DK DK94927309T patent/DK0666746T3/da active
- 1994-09-01 DE DE69427634T patent/DE69427634T2/de not_active Expired - Fee Related
- 1994-09-01 ES ES94927309T patent/ES2160128T3/es not_active Expired - Lifetime
- 1994-09-01 PT PT94927309T patent/PT666746E/pt unknown
- 1994-09-01 JP JP07508253A patent/JP3143749B2/ja not_active Expired - Fee Related
- 1994-09-01 AU AU76794/94A patent/AU7679494A/en not_active Abandoned
- 1994-09-01 WO PCT/US1994/009852 patent/WO1995006472A1/en not_active Ceased
- 1994-09-01 AT AT94927309T patent/ATE202707T1/de not_active IP Right Cessation
- 1994-09-01 EP EP94927309A patent/EP0666746B1/en not_active Expired - Lifetime
- 1994-09-01 CA CA002148373A patent/CA2148373A1/en not_active Abandoned
2001
- 2001-09-18 GR GR20010401526T patent/GR3036666T3/el not_active IP Right Cessation

Also Published As

Publication number	Publication date
DE69427634D1 (de)	2001-08-09
EP0666746B1 (en)	2001-07-04
WO1995006472A1 (en)	1995-03-09
DE69427634T2 (de)	2002-05-08
ES2160128T3 (es)	2001-11-01
JP3143749B2 (ja)	2001-03-07
EP0666746A4 (en)	1998-01-21
ATE202707T1 (de)	2001-07-15
JPH08503491A (ja)	1996-04-16
CA2148373A1 (en)	1995-03-09
AU7679494A (en)	1995-03-22
DK0666746T3 (da)	2001-10-01
EP0666746A1 (en)	1995-08-16
PT666746E (pt)	2001-11-30

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Legal Events

Date	Code	Title	Description
2006-04-04	ML	Lapse due to non-payment of fees