GR71699B - - Google Patents
Info
- Publication number
- GR71699B GR71699B GR54197A GR770154197A GR71699B GR 71699 B GR71699 B GR 71699B GR 54197 A GR54197 A GR 54197A GR 770154197 A GR770154197 A GR 770154197A GR 71699 B GR71699 B GR 71699B
- Authority
- GR
- Greece
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/08—Preparation of carboxylic acids or their salts, halides or anhydrides from nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/04—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having less than three double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/08—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/12—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/14—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/20—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/725,597 US4230705A (en) | 1976-09-22 | 1976-09-22 | 6-Phenyl-1,2,4-triazolo[4,3-b]pyridazines and their uses in treating anxiety |
| US73039576A | 1976-10-07 | 1976-10-07 | |
| US73547576A | 1976-10-26 | 1976-10-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GR71699B true GR71699B (en) | 1983-06-21 |
Family
ID=27419081
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR54197A GR71699B (en) | 1976-09-22 | 1977-08-19 |
Country Status (19)
| Country | Link |
|---|---|
| JP (1) | JPS5340798A (en) |
| AR (2) | AR218036A1 (en) |
| AT (1) | AT360034B (en) |
| AU (1) | AU513760B2 (en) |
| BG (1) | BG29287A3 (en) |
| CA (1) | CA1080712A (en) |
| DD (1) | DD132586A5 (en) |
| DE (1) | DE2741763A1 (en) |
| DK (1) | DK417377A (en) |
| ES (3) | ES462543A1 (en) |
| FI (1) | FI772802A7 (en) |
| FR (1) | FR2442848A1 (en) |
| GB (1) | GB1589237A (en) |
| GR (1) | GR71699B (en) |
| LU (1) | LU78150A1 (en) |
| NL (1) | NL7710389A (en) |
| NO (1) | NO773245L (en) |
| PT (1) | PT67067B (en) |
| RO (1) | RO72226A (en) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GR70309B (en) * | 1979-10-29 | 1982-09-08 | Dow Chemical Co | |
| FR2473522A1 (en) * | 1980-01-16 | 1981-07-17 | Synthelabo | NOVEL DIHYDRO-2,3 IMIDAZO (1,2-B) PYRIDAZINE SUBSTITUTED DERIVATIVES AND MEDICAMENTS, PARTICULARLY USEFUL AS ANTIDEPRESSANTS, CONTAINING THEM |
| EP0036711B1 (en) * | 1980-03-22 | 1985-12-04 | Fbc Limited | Pesticidal heterocyclic compounds, processes for preparing them, compositions containing them, and their use |
| DE3217325A1 (en) * | 1982-05-08 | 1983-11-10 | Hoechst Ag, 6230 Frankfurt | 3-AMINO-6-ARYL-1,2,4-TRIAZOLO (4,3-B) -PYRIDAZINE, THEIR PRODUCTION AND USE |
| US4487930A (en) * | 1982-09-07 | 1984-12-11 | The Dow Chemical Company | 6-[(Cyclic amino)alkylamino]-tetrahydrotriazolo[3,4-a]phthalazines |
| FR2562071B1 (en) * | 1984-03-30 | 1986-12-19 | Sanofi Sa | TRIAZOLO (4,3-B) PYRIDAZINES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
| US4767765A (en) * | 1985-10-31 | 1988-08-30 | American Cyanamid Company | N-substituted-N-[3-(1,2,4-triazolo-[4,3-b]pyridazin-6-yl)phenyl]alkanamides, carbamates and ureas |
| US4654343A (en) * | 1985-10-31 | 1987-03-31 | American Cyanamid Company | N-substituted-N[3-(1,2,4-triazolo[4,3-b]pyridazin-6-yl)phenyl]alkanamides, carbamates and ureas |
| EP0915875B1 (en) | 1996-07-25 | 2003-04-09 | MERCK SHARP & DOHME LTD. | Substituted triazolo-pyridazine derivatives as ligands for gaba receptors |
| AU746866B2 (en) * | 1998-01-14 | 2002-05-02 | Merck Sharp & Dohme Limited | Triazolo-pyridazine derivatives as ligands for GABA receptors |
| GB9801210D0 (en) | 1998-01-21 | 1998-03-18 | Merck Sharp & Dohme | Therapeutic agents |
| MXPA00007135A (en) * | 1998-01-21 | 2002-11-07 | Merck Sharp & Dohme | Triazolo-pyridazine derivatives as ligands for gaba receptors. |
| GB9801208D0 (en) * | 1998-01-21 | 1998-03-18 | Merck Sharp & Dohme | Therapeutic agents |
| GB9801202D0 (en) | 1998-01-21 | 1998-03-18 | Merck Sharp & Dohme | Therapeutic agents |
| GB9801234D0 (en) * | 1998-01-21 | 1998-03-18 | Merck Sharp & Dohme | Therapeutic agents |
| GB9801397D0 (en) | 1998-01-22 | 1998-03-18 | Merck Sharp & Dohme | Therapeutic agents |
| GB9801538D0 (en) | 1998-01-23 | 1998-03-25 | Merck Sharp & Dohme | Pharmaceutical product |
| WO2005077953A1 (en) * | 2004-02-18 | 2005-08-25 | Banyu Pharmaceutical Co., Ltd. | Nitrogenous fused heteroaromatic ring derivative |
| CA3281817A1 (en) | 2016-11-28 | 2026-03-02 | Praxis Precision Medicines, Inc. | Compounds and their methods of use |
| IL309843B2 (en) * | 2018-05-30 | 2026-05-01 | Praxis Prec Medicines Inc | [1,2,4]triazolo[4,3-a]pyridine derivatives and their use as sodium ion channel modulators |
| EA202092908A1 (en) | 2018-09-28 | 2021-05-14 | Праксис Пресижн Медсинз, Инк. | ION CHANNEL MODULATORS |
| US11773099B2 (en) | 2019-05-28 | 2023-10-03 | Praxis Precision Medicines, Inc. | Compounds and their methods of use |
| US11505554B2 (en) | 2019-05-31 | 2022-11-22 | Praxis Precision Medicines, Inc. | Substituted pyridines as ion channel modulators |
| PE20221280A1 (en) | 2019-11-27 | 2022-09-05 | Praxis Prec Medicines Inc | ION CHANNEL MODULATOR FORMULATIONS AND METHODS OF PREPARATION AND USE OF ION CHANNEL MODULATORS |
| CN115087657B (en) * | 2019-12-18 | 2025-01-21 | 加利福尼亚大学董事会 | LIN28 inhibitors and methods of use thereof |
| KR20250005348A (en) | 2022-04-26 | 2025-01-09 | 프락시스 프리시젼 메디신즈, 인크. | Treatment of neurological disorders |
-
1977
- 1977-08-16 CA CA284,806A patent/CA1080712A/en not_active Expired
- 1977-08-19 GR GR54197A patent/GR71699B/el unknown
- 1977-09-07 AR AR269126A patent/AR218036A1/en active
- 1977-09-16 DE DE19772741763 patent/DE2741763A1/en not_active Withdrawn
- 1977-09-20 RO RO7791618A patent/RO72226A/en unknown
- 1977-09-20 LU LU78150A patent/LU78150A1/xx unknown
- 1977-09-20 BG BG037371A patent/BG29287A3/en unknown
- 1977-09-21 NO NO773245A patent/NO773245L/en unknown
- 1977-09-21 AT AT677577A patent/AT360034B/en not_active IP Right Cessation
- 1977-09-21 DK DK417377A patent/DK417377A/en unknown
- 1977-09-21 AU AU28995/77A patent/AU513760B2/en not_active Expired
- 1977-09-22 FR FR7728639A patent/FR2442848A1/en active Pending
- 1977-09-22 NL NL7710389A patent/NL7710389A/en not_active Application Discontinuation
- 1977-09-22 JP JP11344877A patent/JPS5340798A/en active Pending
- 1977-09-22 FI FI772802A patent/FI772802A7/en not_active Application Discontinuation
- 1977-09-22 PT PT67067A patent/PT67067B/en unknown
- 1977-09-22 DD DD7700201157A patent/DD132586A5/en unknown
- 1977-09-22 GB GB39619/77A patent/GB1589237A/en not_active Expired
- 1977-09-22 ES ES462543A patent/ES462543A1/en not_active Expired
-
1978
- 1978-12-18 AR AR274489A patent/AR217886A1/en active
-
1979
- 1979-02-16 ES ES477799A patent/ES477799A1/en not_active Expired
- 1979-02-16 ES ES477800A patent/ES477800A1/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| LU78150A1 (en) | 1978-01-23 |
| DD132586A5 (en) | 1978-10-11 |
| FR2442848A1 (en) | 1980-06-27 |
| ES462543A1 (en) | 1979-06-16 |
| DE2741763A1 (en) | 1978-03-23 |
| JPS5340798A (en) | 1978-04-13 |
| ES477800A1 (en) | 1979-10-16 |
| DK417377A (en) | 1978-03-23 |
| BG29287A3 (en) | 1980-10-15 |
| PT67067A (en) | 1977-10-01 |
| NL7710389A (en) | 1978-03-28 |
| PT67067B (en) | 1979-02-19 |
| AT360034B (en) | 1980-12-10 |
| ES477799A1 (en) | 1980-04-01 |
| RO72226A (en) | 1982-09-09 |
| GB1589237A (en) | 1981-05-07 |
| AU2899577A (en) | 1979-03-29 |
| CA1080712A (en) | 1980-07-01 |
| AR217886A1 (en) | 1980-04-30 |
| AU513760B2 (en) | 1980-12-18 |
| FI772802A7 (en) | 1978-03-23 |
| ATA677577A (en) | 1980-05-15 |
| NO773245L (en) | 1978-03-28 |
| AR218036A1 (en) | 1980-05-15 |