GR75903B - - Google Patents

Info

Publication number
GR75903B
GR75903B GR67142A GR820167142A GR75903B GR 75903 B GR75903 B GR 75903B GR 67142 A GR67142 A GR 67142A GR 820167142 A GR820167142 A GR 820167142A GR 75903 B GR75903 B GR 75903B
Authority
GR
Greece
Application number
GR67142A
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of GR75903B publication Critical patent/GR75903B/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/74—Quinazolines; Hydrogenated quinazolines with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to ring carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
GR67142A 1981-03-06 1982-01-28 GR75903B (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/241,317 US4343940A (en) 1979-02-13 1981-03-06 Anti-tumor quinazoline compounds

Publications (1)

Publication Number Publication Date
GR75903B true GR75903B (el) 1984-08-02

Family

ID=22910195

Family Applications (1)

Application Number Title Priority Date Filing Date
GR67142A GR75903B (el) 1981-03-06 1982-01-28

Country Status (31)

Country Link
US (1) US4343940A (el)
JP (1) JPS57158780A (el)
KR (1) KR880001852B1 (el)
AR (1) AR231138A1 (el)
AT (1) AT380476B (el)
AU (1) AU556099B2 (el)
BE (1) BE891936A (el)
CA (1) CA1163995A (el)
CH (1) CH647776A5 (el)
CY (1) CY1371A (el)
DE (1) DE3203770C2 (el)
DK (1) DK159442C (el)
ES (1) ES509434A0 (el)
FI (1) FI71559C (el)
FR (1) FR2501207B1 (el)
GB (1) GB2094295B (el)
GR (1) GR75903B (el)
HK (1) HK4588A (el)
HU (1) HU189997B (el)
IE (1) IE52385B1 (el)
IL (1) IL64875A0 (el)
IT (1) IT1154272B (el)
KE (1) KE3715A (el)
LU (1) LU83903A1 (el)
NL (1) NL8200473A (el)
NZ (1) NZ199576A (el)
PH (1) PH18529A (el)
PT (1) PT74394B (el)
SE (1) SE461732B (el)
SG (1) SG30787G (el)
YU (1) YU42031B (el)

Families Citing this family (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3131365A1 (de) * 1981-08-07 1983-02-24 Henkel KGaA, 4000 Düsseldorf Neue diglycidyl-substituierte heterocyclische verbindungen, verfahren zu ihrer herstellung und ihre verwendung in arzneimittelzubereitungen mit cytostatischer wirksamkeit
US4963554A (en) * 1990-02-14 1990-10-16 Ortho Pharmaceutical Corporation 6,7-dimethoxy-1,2-dihydro-2-arylquinazoline-3-oxides
US5030635A (en) * 1990-02-14 1991-07-09 Ortho Pharmaceutical Corporation 6-7-dimethoxy-1,2-dihydro-2-arylquinazoline-3-oxides
US5710158A (en) * 1991-05-10 1998-01-20 Rhone-Poulenc Rorer Pharmaceuticals Inc. Aryl and heteroaryl quinazoline compounds which inhibit EGF and/or PDGF receptor tyrosine kinase
US5480883A (en) * 1991-05-10 1996-01-02 Rhone-Poulenc Rorer Pharmaceuticals Inc. Bis mono- and bicyclic aryl and heteroaryl compounds which inhibit EGF and/or PDGF receptor tyrosine kinase
US6645969B1 (en) * 1991-05-10 2003-11-11 Aventis Pharmaceuticals Inc. Aryl and heteroaryl quinazoline compounds which inhibit CSF-1R receptor tyrosine kinase
USRE37650E1 (en) 1991-05-10 2002-04-09 Aventis Pharmacetical Products, Inc. Aryl and heteroaryl quinazoline compounds which inhibit CSF-1R receptor tyrosine kinase
US5714493A (en) * 1991-05-10 1998-02-03 Rhone-Poulenc Rorer Pharmaceuticals, Inc. Aryl and heteroaryl quinazoline compounds which inhibit CSF-1R receptor tyrosine kinase
PT100905A (pt) * 1991-09-30 1994-02-28 Eisai Co Ltd Compostos heterociclicos azotados biciclicos contendo aneis de benzeno, ciclo-hexano ou piridina e de pirimidina, piridina ou imidazol substituidos e composicoes farmaceuticas que os contem
DE69422450T2 (de) * 1993-06-29 2000-06-08 Takeda Chemical Industries, Ltd. Chinoline oder Chinazolin-Derivate und deren Verwendung zur Herstellung eines Medikaments für die Behandlung von Osteoporose
AU686843B2 (en) * 1994-02-23 1998-02-12 Pfizer Inc. 4-heterocyclyl-substituted quinazoline derivatives, processes for their preparation and their use as anti-cancer agents
US5804396A (en) * 1994-10-12 1998-09-08 Sugen, Inc. Assay for agents active in proliferative disorders
TW321649B (el) * 1994-11-12 1997-12-01 Zeneca Ltd
GB9424233D0 (en) * 1994-11-30 1995-01-18 Zeneca Ltd Quinazoline derivatives
US5837815A (en) * 1994-12-15 1998-11-17 Sugen, Inc. PYK2 related polypeptide products
US5837524A (en) * 1994-12-15 1998-11-17 Sugen, Inc. PYK2 related polynucleotide products
GB9508537D0 (en) * 1995-04-27 1995-06-14 Zeneca Ltd Quinazoline derivatives
EP0824525B1 (en) * 1995-04-27 2001-06-13 AstraZeneca AB Quinazoline derivatives
GB9508538D0 (en) * 1995-04-27 1995-06-14 Zeneca Ltd Quinazoline derivatives
GB9508565D0 (en) * 1995-04-27 1995-06-14 Zeneca Ltd Quiazoline derivative
GB9508535D0 (en) * 1995-04-27 1995-06-14 Zeneca Ltd Quinazoline derivative
EP0832073B1 (en) * 1995-06-07 2002-01-16 Sugen, Inc. Quinazolines and pharmaceutical compositions
WO1997017329A1 (en) * 1995-11-07 1997-05-15 Kirin Beer Kabushiki Kaisha Quinoline derivatives and quinazoline derivatives inhibiting autophosphorylation of growth factor receptor originating in platelet and pharmaceutical compositions containing the same
US6716575B2 (en) 1995-12-18 2004-04-06 Sugen, Inc. Diagnosis and treatment of AUR1 and/or AUR2 related disorders
US7119174B2 (en) * 1995-12-18 2006-10-10 Sugen, Inc. Diagnosis and treatment of AUR1 and/or AUR2 related disorders
GB9624482D0 (en) * 1995-12-18 1997-01-15 Zeneca Phaema S A Chemical compounds
JP4471404B2 (ja) 1996-02-13 2010-06-02 アストラゼネカ ユーケイ リミテッド Ｖｅｇｆインヒビターとしてのキナゾリン誘導体
GB9603095D0 (en) * 1996-02-14 1996-04-10 Zeneca Ltd Quinazoline derivatives
GB9603097D0 (en) * 1996-02-14 1996-04-10 Zeneca Ltd Quinazoline compounds
ATE211134T1 (de) 1996-03-05 2002-01-15 4-anilinochinazolin derivate
GB9607729D0 (en) * 1996-04-13 1996-06-19 Zeneca Ltd Quinazoline derivatives
GB9718972D0 (en) 1996-09-25 1997-11-12 Zeneca Ltd Chemical compounds
WO1998026054A2 (en) * 1996-12-11 1998-06-18 Sugen, Inc. Pyk2 related products and methods
US6818440B2 (en) * 1997-04-28 2004-11-16 Sugen, Inc. Diagnosis and treatment of alk-7 related disorders
US6228641B1 (en) 1997-05-20 2001-05-08 Sugen, Inc. Diagnosis and treatment of PTP04 related disorders
US6342593B1 (en) 1997-06-11 2002-01-29 Sugen, Inc. Diagnosis and treatment of ALP related disorders
US7115710B2 (en) * 1997-06-11 2006-10-03 Sugen, Inc. Diagnosis and treatment of PTP related disorders
US6388063B1 (en) 1997-06-18 2002-05-14 Sugen, Inc. Diagnosis and treatment of SAD related disorders
AU2237899A (en) * 1998-01-21 1999-08-09 Sugen, Inc. Human orthologues of wart
ATE302269T1 (de) 1998-04-14 2005-09-15 Sugen Inc Ste20-verwandte proteinkinasen
MXPA00011773A (es) 1998-05-28 2002-06-04 Parker Hughes Inst Quinazolinas para tratar tumores en el cerebro.
US6800649B1 (en) * 1998-06-30 2004-10-05 Parker Hughes Institute Method for inhibiting c-jun expression using JAK-3 inhibitors
EP1105378B1 (en) * 1998-08-21 2005-03-30 Parker Hughes Institute Quinazoline derivatives
US6861442B1 (en) * 1998-12-30 2005-03-01 Sugen, Inc. PYK2 and inflammation
US6080747A (en) * 1999-03-05 2000-06-27 Hughes Institute JAK-3 inhibitors for treating allergic disorders
US6258820B1 (en) 1999-03-19 2001-07-10 Parker Hughes Institute Synthesis and anti-tumor activity of 6,7-dialkoxy-4-phenylamino-quinazolines
US20030162223A1 (en) * 1999-10-22 2003-08-28 Lowery David E. Drosophila G protein coupled receptors, nucleic acids, and methods related to the same
US7364866B2 (en) * 1999-10-22 2008-04-29 Pharmacia & Upjohn Company Drosophila G protein coupled receptors, nucleic acids, and methods related to the same
JP2003512838A (ja) * 1999-10-22 2003-04-08 ファルマシア・アンド・アップジョン・カンパニー ショウジョウバエｇタンパク質結合レセプター、核酸、およびそれに関連する方法。
PL203782B1 (pl) 1999-11-05 2009-11-30 Astrazeneca Ab Pochodne chinazoliny,sposoby ich wytwarzania,ich kompozycje farmaceutyczne oraz ich zastosowania
US20030082534A1 (en) * 1999-11-16 2003-05-01 Peter Lind Novel G protein-coupled receptors
AU784543B2 (en) * 1999-11-16 2006-04-27 Pharmacia & Upjohn Company Novel G protein-coupled receptors
US20030003451A1 (en) * 2000-02-23 2003-01-02 Gabriel Vogeli Novel G protein-coupled receptors
AU779695B2 (en) * 2000-04-07 2005-02-10 Astrazeneca Ab Quinazoline compounds
US20050069976A1 (en) * 2001-02-14 2005-03-31 Peter Lind Protein-coupled receptor
US8450302B2 (en) * 2002-08-02 2013-05-28 Ab Science 2-(3-aminoaryl) amino-4-aryl-thiazoles and their use as c-kit inhibitors
MXPA05001277A (es) 2002-08-02 2005-10-06 Ab Science 2-(3-aminoaril)amino-4-aril-tiazoles y su uso como inhibidores del c-kit.
EP1684750B1 (en) * 2003-10-23 2010-04-28 AB Science 2-aminoaryloxazole compounds as tyrosine kinase inhibitors
CA2603826C (en) 2005-04-04 2013-03-12 Ab Science Substituted oxazole derivatives and their use as tyrosine kinase inhibitors
US8246966B2 (en) * 2006-08-07 2012-08-21 University Of Georgia Research Foundation, Inc. Trypanosome microsome system and uses thereof
JP2010505811A (ja) 2006-10-04 2010-02-25 ファイザー・プロダクツ・インク カルシウム受容体アンタゴニストとしてのピリド［４，３−ｄ］ピリミジン−４（３Ｈ）−オン誘導体
US8338433B2 (en) * 2006-11-22 2012-12-25 University Of Georgia Research Foundation, Inc. Tyrosine kinase inhibitors as anti-kinetoplastid agents
JP2010511382A (ja) * 2006-12-01 2010-04-15 エージェンシー フォー サイエンス，テクノロジー アンド リサーチ 癌関連タンパク質キナーゼ
AU2012225693A1 (en) 2011-03-04 2013-09-19 Newgen Therapeutics, Inc. Alkyne substituted quinazoline compound and methods of use

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3298291A (en) * 1965-12-28 1967-01-17 Jack D Layton Paver screed assembly
US3455920A (en) * 1967-01-13 1969-07-15 Squibb & Sons Inc 2,3-dihydro-5 and 6-substituted-2-phenyl-4(1h)-quinazolinones
US3637693A (en) * 1968-07-12 1972-01-25 Du Pont Hydroxyarylquinazolines and their use as uv-absorbers
DE2050092C3 (de) 1970-10-13 1980-04-24 Bayer Ag, 5090 Leverkusen Chinazolondiurethane, Verfahren zu ihrer Herstellung sowie Arzneimittel, die diese Verbindungen enthalten
AU438472B2 (en) * 1970-12-23 1973-08-09 Sumitomo Chemical Company, Limited Quinazolinone derivatives anda process for production thereof
JPS6011032B2 (ja) 1975-12-16 1985-03-22 大鵬薬品工業株式会社 ２―置換―５―フルオルピリミジン―４―オン誘導体の製造法
US4080455A (en) * 1975-12-16 1978-03-21 Taisho Pharmaceutical Company Limited 5-Fluoropyrimidin-4-one compositions

Also Published As

Publication number Publication date
SE461732B (sv) 1990-03-19
IT1154272B (it) 1987-01-21
ES8304095A1 (es) 1983-02-16
JPH0337552B2 (el) 1991-06-05
IT8247713A0 (it) 1982-02-03
GB2094295A (en) 1982-09-15
PT74394B (en) 1984-10-22
DK159442C (da) 1991-03-18
PT74394A (en) 1982-03-01
PH18529A (en) 1985-08-02
DK50482A (da) 1982-09-07
IE52385B1 (en) 1987-10-14
ATA39582A (de) 1985-10-15
FR2501207B1 (fr) 1985-12-06
NL8200473A (nl) 1982-10-01
DE3203770A1 (de) 1982-11-11
CH647776A5 (de) 1985-02-15
HU189997B (en) 1986-08-28
KR830009050A (ko) 1983-12-17
FI820399L (fi) 1982-09-07
AU7998182A (en) 1982-09-09
LU83903A1 (fr) 1982-09-13
YU42031B (en) 1988-04-30
KE3715A (en) 1987-04-16
IT8247713A1 (it) 1983-08-03
SG30787G (en) 1988-09-16
US4343940A (en) 1982-08-10
IL64875A0 (en) 1982-03-31
AR231138A1 (es) 1984-09-28
DK159442B (da) 1990-10-15
AU556099B2 (en) 1986-10-23
FR2501207A1 (fr) 1982-09-10
SE8200526L (sv) 1982-09-07
YU25682A (en) 1985-03-20
NZ199576A (en) 1986-05-09
GB2094295B (en) 1984-09-12
CA1163995A (en) 1984-03-20
HK4588A (en) 1988-01-29
CY1371A (en) 1987-08-07
FI71559B (fi) 1986-10-10
DE3203770C2 (de) 1993-11-04
ES509434A0 (es) 1983-02-16
FI71559C (fi) 1987-01-19
AT380476B (de) 1986-05-26
KR880001852B1 (ko) 1988-09-22
BE891936A (fr) 1982-07-28
JPS57158780A (en) 1982-09-30
IE820163L (en) 1982-09-06

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