GT200200044A - Compuestos farmaceuticamente activos - Google Patents
Compuestos farmaceuticamente activosInfo
- Publication number
- GT200200044A GT200200044A GT200200044A GT200200044A GT200200044A GT 200200044 A GT200200044 A GT 200200044A GT 200200044 A GT200200044 A GT 200200044A GT 200200044 A GT200200044 A GT 200200044A GT 200200044 A GT200200044 A GT 200200044A
- Authority
- GT
- Guatemala
- Prior art keywords
- pharmaceutically active
- active compounds
- female sexual
- grupo
- female
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- NYHBQMYGNKIUIF-UUOKFMHZSA-N Guanosine Chemical compound C1=NC=2C(=O)NC(N)=NC=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O NYHBQMYGNKIUIF-UUOKFMHZSA-N 0.000 abstract 2
- 230000001568 sexual effect Effects 0.000 abstract 2
- GAWIXWVDTYZWAW-UHFFFAOYSA-N C[CH]O Chemical class C[CH]O GAWIXWVDTYZWAW-UHFFFAOYSA-N 0.000 abstract 1
- MIKUYHXYGGJMLM-GIMIYPNGSA-N Crotonoside Natural products C1=NC2=C(N)NC(=O)N=C2N1[C@H]1O[C@@H](CO)[C@H](O)[C@@H]1O MIKUYHXYGGJMLM-GIMIYPNGSA-N 0.000 abstract 1
- NYHBQMYGNKIUIF-UHFFFAOYSA-N D-guanosine Natural products C1=2NC(N)=NC(=O)C=2N=CN1C1OC(CO)C(O)C1O NYHBQMYGNKIUIF-UHFFFAOYSA-N 0.000 abstract 1
- 208000010228 Erectile Dysfunction Diseases 0.000 abstract 1
- 206010057671 Female sexual dysfunction Diseases 0.000 abstract 1
- 229940029575 guanosine Drugs 0.000 abstract 1
- 201000001881 impotence Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Reproductive Health (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Gynecology & Obstetrics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
LA PRESENTE INVENCION SE REFIERE A COMPUESTOS FARMACEUTICAMENTE ACTIVOS EN ESPECIAL DEL 5[2 BUTOXI5(1HIDROXIETIL)3PIRIDINIL]3ETIL2(1ETIL3AZETIDINIL)2,6DIHIDRO7HPIRAZOLO[4,3D] PIRIMIDIN7ONA DE FORMULA GENERAL (I) EN DONDE R1 ES UN GRUPO FUNCIONAL DESCRITO EN EL EXPEDIENTE. ESTOS COMPUESTOS INHIBEN LAS FOSFODIESTERASAS DE GUANOSINA 3',5'MONOFOSFATO CICLICO (GMPC PDE) POR LO QUE SON UTILES EN CASOS TALES COMO LA DISFUNCION ERECTIL MASCULINA, DISFUNCION SEXUAL FEMENINA, TRASTORNO DEL DOLOR SEXUAL FEMENINO, DISFUNCION SEXUAL DEBIDA A LESIONES DE LA MEDULA ESPINAL.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0105893.2A GB0105893D0 (en) | 2001-03-09 | 2001-03-09 | Pharmaceutically active compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GT200200044A true GT200200044A (es) | 2002-12-02 |
Family
ID=9910362
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GT200200044A GT200200044A (es) | 2001-03-09 | 2002-03-06 | Compuestos farmaceuticamente activos |
Country Status (8)
| Country | Link |
|---|---|
| AP (1) | AP2002002462A0 (es) |
| GB (1) | GB0105893D0 (es) |
| GT (1) | GT200200044A (es) |
| HN (1) | HN2002000050A (es) |
| PA (1) | PA8541101A1 (es) |
| PE (1) | PE20021153A1 (es) |
| TN (1) | TNSN02023A1 (es) |
| WO (1) | WO2002072586A1 (es) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10675280B2 (en) | 2001-10-20 | 2020-06-09 | Sprout Pharmaceuticals, Inc. | Treating sexual desire disorders with flibanserin |
| UA78974C2 (en) | 2001-10-20 | 2007-05-10 | Boehringer Ingelheim Pharma | Use of flibanserin for treating disorders of sexual desire |
| AU2003303041B2 (en) | 2002-12-13 | 2008-07-24 | Warner-Lambert Company Llc | Alpha-2-delta ligand to treat lower urinary tract symptoms |
| BRPI0411985A (pt) * | 2003-07-16 | 2006-08-29 | Pfizer | tratamento da disfunção sexual |
| JP2009503020A (ja) | 2005-08-03 | 2009-01-29 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 肥満症の治療におけるフリバンセリンの使用 |
| CA2626134C (en) | 2005-10-29 | 2013-12-24 | Boehringer Ingelheim International Gmbh | Benzimidazolone derivatives for the treatment of premenstrual and other female sexual disorders |
| EP2037927B1 (en) | 2006-06-30 | 2010-01-27 | Boehringer Ingelheim International GmbH | Flibanserin for the treatment of urinary incontinence and related diseases |
| JP5793828B2 (ja) | 2006-08-14 | 2015-10-14 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | フリバンセリンの製剤及びその製造方法 |
| KR20090045945A (ko) | 2006-08-25 | 2009-05-08 | 베링거 인겔하임 인터내셔날 게엠베하 | 제어 방출 시스템 및 이의 제조방법 |
| CL2008002693A1 (es) | 2007-09-12 | 2009-10-16 | Boehringer Ingelheim Int | Uso de flibanserina para el tratamiento de sintomas vasomotores seleccionados de sofocos, sudores nocturnos, cambios de estado de animo e irritabilidad |
| CA2686480A1 (en) | 2008-12-15 | 2010-06-15 | Boehringer Ingelheim International Gmbh | New salts |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RS50011B (sr) * | 1998-04-20 | 2008-09-29 | Pfizer Inc., | Derivati piridin-3-karboksilne kiseline i njihova upotreba kao intermedijera |
| GB9823101D0 (en) * | 1998-10-23 | 1998-12-16 | Pfizer Ltd | Pharmaceutically active compounds |
| HK1049834A1 (zh) * | 1999-10-11 | 2003-05-30 | 辉瑞大药厂 | 用作磷酸二酯酶抑制剂的5-(2-取代的-5-杂环基磺酰基吡啶-3-基)-二氢吡唑并[4，3-d]嘧啶-7-酮类化合物 |
| CO5271697A1 (es) * | 2000-01-12 | 2003-04-30 | Pfizer Prod Inc | Composiciones y procedimientos para el tratamiento de afecciones que responden a un aumento de testosterona |
-
2001
- 2001-03-09 GB GBGB0105893.2A patent/GB0105893D0/en not_active Ceased
-
2002
- 2002-02-27 WO PCT/IB2002/000622 patent/WO2002072586A1/en not_active Ceased
- 2002-03-06 GT GT200200044A patent/GT200200044A/es unknown
- 2002-03-07 AP APAP/P/2002/002462A patent/AP2002002462A0/en unknown
- 2002-03-07 PE PE2002000183A patent/PE20021153A1/es not_active Application Discontinuation
- 2002-03-08 TN TNTNSN02023A patent/TNSN02023A1/fr unknown
- 2002-03-08 HN HN2002000050A patent/HN2002000050A/es unknown
- 2002-03-08 PA PA20028541101A patent/PA8541101A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PA8541101A1 (es) | 2003-11-12 |
| TNSN02023A1 (fr) | 2005-12-23 |
| WO2002072586A1 (en) | 2002-09-19 |
| HN2002000050A (es) | 2002-09-13 |
| AP2002002462A0 (en) | 2002-06-30 |
| GB0105893D0 (en) | 2001-04-25 |
| PE20021153A1 (es) | 2002-12-17 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EA200200337A1 (ru) | ПРОИЗВОДНЫЕ ПИРАЗОЛО[4,3-d]ПИРИМИДИНА | |
| GT199900053A (es) | Pirazolopirimidinonas inhibidoras de gmpc pde5 para el tratamiento de la disfuncion sexual. | |
| GT200200044A (es) | Compuestos farmaceuticamente activos | |
| PE20040197A1 (es) | Pirazolopiridinas sustituidas con carbamato | |
| EA200600190A1 (ru) | Производные пиримидин-2,4-диона в качестве антагонистов рецептора гонадотропин-высвобождающего гормона | |
| GT200100016A (es) | Pirido[2,3,-d]pirimidin-2,7-diaminas inhibidoras de cinasas. | |
| DOP2001000271A (es) | Compuestos de imidazol condensado con arilo o heteroarilo como agentes antiinflamatorios y analgésicos. | |
| PA8593001A1 (es) | Derivados de pirimidina para el tratamiento del crecimiento celular anormal | |
| AR030609A1 (es) | Composicion catartica | |
| UY25671A1 (es) | Procedimiento para preparar imidazotrazinonas sustituidas por 2-fenilo | |
| ES2188604T3 (es) | Inhibidores de proteasa del vih en combinaciones farmaceuticas para eltratamiento del sida. | |
| IL143388A0 (en) | Compositions and methods for stimulating gastrointestinal motility | |
| GT200100137A (es) | Pro-drogas de derivados de 4-fenil-piridina. | |
| BRPI0412327A (pt) | derivados de pirimidina-2,4-diona como antagonistas de receptor de hormÈnio liberador de gonadotropina | |
| BR0210261A (pt) | Formulações farmacêuticas para a administração eficiente de apomorfina, 6ar-(-)-n-propil-norapomorfina e seus derivados e pró-drogas destes | |
| GT199800207A (es) | Nuevos derivados de la eritromicina. | |
| PA8527901A1 (es) | Derivados de quinazolin como un antagonista del adrenèrgico alfa-1 | |
| GT200100251A (es) | Procedimiento para la preparacion de imidazotriazinonas substituidas con sulfonamida | |
| UY28524A1 (es) | Derivados de triazol sustituidos como antagonistas de oxitocina | |
| PE20011223A1 (es) | Composicion farmaceutica que comprende pemetrexed y un antioxidante como monotioglicerol, l-cisteina y acido tioglicolico | |
| GT200200070A (es) | Composiciones que contienen imidazotriazinona para administracion nasal | |
| EP1634883A4 (en) | 2-SUBSTITUTED PHENYL-5,7-DIALKYL-3,7-DIHYDROPYRROLO-2,3-PYRIMIDIN-4-ONDERIVATES, THEIR PREPARATION AND PHARMACEUTICAL USE | |
| PA8474401A1 (es) | 3-ceto derivados triciclicos de 6-0-metileritromicina | |
| PT1259229E (pt) | Utilizacao de benzotieno-[2,3-d]-pirimidinas com uma accao inibidora da pde v no tratamento do disfuncao erectil | |
| AR032519A1 (es) | Compuestos |