GT201700184A - Nuevas proteínas específicas para pioverdina y pioquelina - Google Patents
Nuevas proteínas específicas para pioverdina y pioquelinaInfo
- Publication number
- GT201700184A GT201700184A GT201700184A GT201700184A GT201700184A GT 201700184 A GT201700184 A GT 201700184A GT 201700184 A GT201700184 A GT 201700184A GT 201700184 A GT201700184 A GT 201700184A GT 201700184 A GT201700184 A GT 201700184A
- Authority
- GT
- Guatemala
- Prior art keywords
- muteines
- pioverdina
- pioquelina
- specific proteins
- description
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 2
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 102000039446 nucleic acids Human genes 0.000 abstract 2
- 108020004707 nucleic acids Proteins 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/005—Enzyme inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/01—Hydrolysed proteins; Derivatives thereof
- A61K38/012—Hydrolysed proteins; Derivatives thereof from animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
LA PRESENTE DESCRIPCIÓN PROPORCIONA MUTEÍNAS DE HNGAL QUE SE UNEN CON UN MIEMBRO DE LA FAMILIA DE PIOVERDINA O PIOQUELINA Y QUE PUEDEN USARSE EN DIVERSAS APLICACIONES INCLUYENDO APLICACIONES FARMACÉUTICAS, POR EJEMPLO, PARA INHIBIR O REDUCIR EL CRECIMIENTO DE P. AERUGINOSA. LA PRESENTE DESCRIPCIÓN TAMBIÉN SE REFIERE A MÉTODOS PARA PREPARAR UNA O MÁS MUTEÍNAS DE UNIÓN A PIOVERDINA O A PIOQUELINA DESCRITAS EN LA PRESENTE MEMORIA ASÍ COMO A COMPOSICIONES QUE COMPRENDEN UNA O MÁS DE DICHAS MUTEÍNAS. LA PRESENTE DESCRIPCIÓN SE REFIERE ADEMÁS A MOLÉCULAS DE ÁCIDO NUCLEICO QUE CODIFICAN DICHAS MUTEÍNAS Y A MÉTODOS PARA LA GENERACIÓN DE DICHAS MUTEÍNAS Y MOLÉCULAS DE ÁCIDO NUCLEICO. ADEMÁS, LA SOLICITUD DESCRIBE USOS TERAPÉUTICOS Y/O DE DIAGNÓSTICO DE ESTAS MUTEÍNAS ASÍ COMO COMPOSICIONES QUE COMPRENDEN UNA O MÁS DE DICHAS MUTEÍNAS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15305242 | 2015-02-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GT201700184A true GT201700184A (es) | 2018-10-24 |
Family
ID=52595246
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GT201700184A GT201700184A (es) | 2015-02-18 | 2017-08-17 | Nuevas proteínas específicas para pioverdina y pioquelina |
Country Status (28)
| Country | Link |
|---|---|
| US (8) | US9884898B2 (es) |
| EP (1) | EP3259282A1 (es) |
| JP (1) | JP6843754B2 (es) |
| KR (1) | KR20170116158A (es) |
| CN (1) | CN107660211A (es) |
| AR (1) | AR103714A1 (es) |
| AU (1) | AU2016221816B2 (es) |
| BR (1) | BR112017017530A2 (es) |
| CA (1) | CA2976687A1 (es) |
| CL (1) | CL2017002082A1 (es) |
| CO (1) | CO2017009433A2 (es) |
| CR (1) | CR20170425A (es) |
| DO (1) | DOP2017000191A (es) |
| EA (1) | EA035824B1 (es) |
| EC (1) | ECSP17061751A (es) |
| GT (1) | GT201700184A (es) |
| HK (1) | HK1245293A1 (es) |
| IL (1) | IL254013A0 (es) |
| MA (1) | MA41072A1 (es) |
| MX (1) | MX375049B (es) |
| PE (1) | PE20171652A1 (es) |
| PH (1) | PH12017501473A1 (es) |
| SG (1) | SG11201706621SA (es) |
| TN (1) | TN2017000348A1 (es) |
| TW (1) | TW201636364A (es) |
| UY (1) | UY36561A (es) |
| WO (1) | WO2016131804A1 (es) |
| ZA (1) | ZA201705257B (es) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112012013662B1 (pt) | 2009-12-07 | 2022-08-02 | Pieris Pharmaceuticals Gmbh | Muteínas de lipocalina associada à gelatinase de neutrófilo humano (lcn2, hngal), seu uso e seus métodos de geração e produção, molécula de ácido nucleico, célula hospedeira, composição farmacêutica e kit de diagnóstico ou analítico |
| SG11201609274SA (en) | 2014-05-22 | 2016-12-29 | Pieris Pharmaceuticals Gmbh | Novel specific-binding polypeptides and uses thereof |
| JP6839087B2 (ja) | 2015-01-28 | 2021-03-03 | ピエリス ファーマシューティカルズ ゲーエムベーハー | 血管新生に特異的な新規のタンパク質 |
| TN2017000348A1 (en) * | 2015-02-18 | 2019-01-16 | Sanofi Sa | Novel proteins specific for pyoverdine and pyochelin |
| KR20170138574A (ko) | 2015-05-04 | 2017-12-15 | 피어이스 파마슈티컬즈 게엠베하 | 항암 융합 폴리펩타이드 |
| KR102734408B1 (ko) | 2015-05-04 | 2024-11-27 | 피어이스 파마슈티컬즈 게엠베하 | Cd137에 특이적인 신규한 단백질 |
| AU2016262838B2 (en) | 2015-05-18 | 2020-10-08 | Pieris Pharmaceuticals Gmbh | Muteins of human lipocalin 2 with affinity for Glypican-3 (GPC3) |
| MX390894B (es) | 2015-05-18 | 2025-03-21 | Pieris Pharmaceuticals Gmbh | Polipéptido de fusión anti-cáncer. |
| EP3115371A1 (en) | 2015-07-07 | 2017-01-11 | Sanofi | Fusion molecules |
| CN108699162A (zh) | 2015-11-30 | 2018-10-23 | 皮里斯澳大利亚有限公司 | 新型抗血管生成融合多肽 |
| TW201725212A (zh) | 2015-12-10 | 2017-07-16 | 第一三共股份有限公司 | 特異性於降鈣素基因相關胜肽的新穎蛋白 |
| WO2018087108A1 (en) * | 2016-11-09 | 2018-05-17 | Pieris Pharmaceuticals Gmbh | Proteins specific for cd137 |
| JP2021530515A (ja) * | 2018-07-19 | 2021-11-11 | ザ・リージエンツ・オブ・ザ・ユニバーシテイ・オブ・コロラド、ア・ボデイー・コーポレイト | 鉄欠乏症および関連する貧血を治療するためのエンテロバクチンの新規使用のための方法、システムおよび組成物 |
| AU2020253034A1 (en) | 2019-03-29 | 2021-08-19 | Pieris Pharmaceuticals Gmbh | Inhaled administration of lipocalin muteins |
| CN116077621B (zh) * | 2021-11-05 | 2026-03-24 | 华南农业大学 | P19蛋白在调控绿脓杆菌毒力中的应用 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH01215289A (ja) | 1988-02-22 | 1989-08-29 | Toa Nenryo Kogyo Kk | 遺伝子組換えによる正常ヒト血清アルブミンaの製造方法 |
| FR2649991B2 (fr) | 1988-08-05 | 1994-03-04 | Rhone Poulenc Sante | Utilisation de derives stables du plasmide pkd1 pour l'expression et la secretion de proteines heterologues dans les levures du genre kluyveromyces |
| US5728553A (en) | 1992-09-23 | 1998-03-17 | Delta Biotechnology Limited | High purity albumin and method of producing |
| US5908621A (en) | 1995-11-02 | 1999-06-01 | Schering Corporation | Polyethylene glycol modified interferon therapy |
| US6620413B1 (en) | 1995-12-27 | 2003-09-16 | Genentech, Inc. | OB protein-polymer chimeras |
| GB9722131D0 (en) | 1997-10-20 | 1997-12-17 | Medical Res Council | Method |
| CA2233725A1 (en) | 1998-03-31 | 1999-09-30 | Hemosol Inc. | Hemoglobin-hydroxyethyl starch complexes |
| CZ298681B6 (cs) | 1998-06-08 | 2007-12-19 | F. Hoffmann-La Roche Ag | Lécivo pro lécení infekcí chronické hepatitis C |
| US6403564B1 (en) | 1998-10-16 | 2002-06-11 | Schering Corporation | Ribavirin-interferon alfa combination therapy for eradicating detectable HCV-RNA in patients having chronic hepatitis C infection |
| JP4469456B2 (ja) * | 2000-04-19 | 2010-05-26 | 第一三共株式会社 | 緑膿菌鉄獲得系阻害物質のスクリーニング法 |
| US7211395B2 (en) | 2001-03-09 | 2007-05-01 | Dyax Corp. | Serum albumin binding moieties |
| US7056702B2 (en) * | 2002-12-16 | 2006-06-06 | Kimberly Clark Co | Detecting lipocalin |
| WO2006056464A2 (en) | 2004-11-26 | 2006-06-01 | Pieris Ag | Compound with affinity for the cytotoxic t lymphocyte-associated antigen (ctla-4) |
| EP1929073A4 (en) | 2005-09-27 | 2010-03-10 | Amunix Inc | PROTEIN MEDICAMENT AND ITS USE |
| JP5711118B2 (ja) | 2008-06-24 | 2015-04-30 | テクニッシュ ウニヴェルジテート ミュンヘン | 所与の標的に対してアフィニティーを有するhNGALおよび類縁タンパク質のムテイン |
| ES2667066T3 (es) * | 2010-05-24 | 2018-05-09 | The Trustees Of Columbia University In The City Of New York | Proteínas NGAL mutantes y usos de las mismas |
| WO2014076321A1 (en) | 2012-11-19 | 2014-05-22 | Pieris Ag | Novel specific-binding polypeptides and uses thereof |
| CN103074303A (zh) * | 2012-12-27 | 2013-05-01 | 中国人民解放军第三军医大学 | 产生抗人ngal特异性单克隆抗体的杂交瘤细胞株及其产生的单克隆抗体与应用 |
| TN2017000348A1 (en) * | 2015-02-18 | 2019-01-16 | Sanofi Sa | Novel proteins specific for pyoverdine and pyochelin |
| EP3115371A1 (en) | 2015-07-07 | 2017-01-11 | Sanofi | Fusion molecules |
-
2016
- 2016-02-16 TN TNP/2017/000348A patent/TN2017000348A1/en unknown
- 2016-02-16 EA EA201791841A patent/EA035824B1/ru not_active IP Right Cessation
- 2016-02-16 BR BR112017017530-4A patent/BR112017017530A2/pt not_active IP Right Cessation
- 2016-02-16 CN CN201680022032.9A patent/CN107660211A/zh active Pending
- 2016-02-16 WO PCT/EP2016/053226 patent/WO2016131804A1/en not_active Ceased
- 2016-02-16 AU AU2016221816A patent/AU2016221816B2/en not_active Ceased
- 2016-02-16 AR ARP160100413A patent/AR103714A1/es unknown
- 2016-02-16 MX MX2017010628A patent/MX375049B/es active IP Right Grant
- 2016-02-16 CA CA2976687A patent/CA2976687A1/en not_active Abandoned
- 2016-02-16 CR CR20170425A patent/CR20170425A/es unknown
- 2016-02-16 EP EP16704641.6A patent/EP3259282A1/en not_active Withdrawn
- 2016-02-16 MA MA41072A patent/MA41072A1/fr unknown
- 2016-02-16 HK HK18104645.1A patent/HK1245293A1/zh unknown
- 2016-02-16 TW TW105104396A patent/TW201636364A/zh unknown
- 2016-02-16 SG SG11201706621SA patent/SG11201706621SA/en unknown
- 2016-02-16 KR KR1020177026032A patent/KR20170116158A/ko not_active Withdrawn
- 2016-02-16 JP JP2017543835A patent/JP6843754B2/ja not_active Expired - Fee Related
- 2016-02-16 PE PE2017001421A patent/PE20171652A1/es unknown
- 2016-02-18 UY UY0001036561A patent/UY36561A/es not_active Application Discontinuation
-
2017
- 2017-05-23 US US15/602,783 patent/US9884898B2/en not_active Expired - Fee Related
- 2017-08-03 ZA ZA2017/05257A patent/ZA201705257B/en unknown
- 2017-08-14 DO DO2017000191A patent/DOP2017000191A/es unknown
- 2017-08-14 CL CL2017002082A patent/CL2017002082A1/es unknown
- 2017-08-14 PH PH12017501473A patent/PH12017501473A1/en unknown
- 2017-08-16 IL IL254013A patent/IL254013A0/en unknown
- 2017-08-17 GT GT201700184A patent/GT201700184A/es unknown
- 2017-09-15 EC ECIEPI201761751A patent/ECSP17061751A/es unknown
- 2017-09-18 CO CONC2017/0009433A patent/CO2017009433A2/es unknown
- 2017-10-05 US US15/726,163 patent/US10072056B2/en not_active Expired - Fee Related
- 2017-10-06 US US15/727,087 patent/US10118952B2/en not_active Expired - Fee Related
- 2017-10-06 US US15/726,577 patent/US10065998B2/en not_active Expired - Fee Related
- 2017-11-16 US US15/814,737 patent/US10329334B2/en not_active Expired - Fee Related
-
2018
- 2018-08-14 US US16/103,645 patent/US20180371037A1/en not_active Abandoned
- 2018-08-14 US US16/103,652 patent/US20180371038A1/en not_active Abandoned
- 2018-08-14 US US16/103,649 patent/US20180346532A1/en not_active Abandoned
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