DOP2017000191A - Nuevas proteínas específicas para pioverdina y pioquelina - Google Patents

Nuevas proteínas específicas para pioverdina y pioquelina

Info

Publication number
DOP2017000191A
DOP2017000191A DO2017000191A DO2017000191A DOP2017000191A DO P2017000191 A DOP2017000191 A DO P2017000191A DO 2017000191 A DO2017000191 A DO 2017000191A DO 2017000191 A DO2017000191 A DO 2017000191A DO P2017000191 A DOP2017000191 A DO P2017000191A
Authority
DO
Dominican Republic
Prior art keywords
muteins
present description
pioverdina
pioquelina
specific proteins
Prior art date
Application number
DO2017000191A
Other languages
English (en)
Inventor
Kruip Jochen
Corvey Carsten
Stump Heike
Calandra Bernhard
Rey Astrid
Mourez Michael
Karst Nathalie
Fraisse Laurent
Rothe Christine
Allersdorfer Andrea
Hinner Marlon
Lunde Bradley
Jansen Kristian
Hülsmeyer Martin
Wiedenmann Alexander
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of DOP2017000191A publication Critical patent/DOP2017000191A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/005—Enzyme inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/01—Hydrolysed proteins; Derivatives thereof
    • A61K38/012—Hydrolysed proteins; Derivatives thereof from animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

La presente descripción proporciona muteínas de hNGAL a las que se une un miembro de la familia de pioverdina o pioquelina y que pueden usarse en diversas aplicaciones incluyendo aplicaciones farmacéuticas, por ejemplo, para inhibir o reducir el crecimiento de P. aeruginosa. La presente descripción también se refiere a métodos para preparar una o más muteínas a las que se une pioverdina o pioquelina descritas en la presente memoria así como a composiciones que comprenden una o más de dichas muteínas. La presente descripción se refiere además a moléculas de ácido nucleico que codifican dichas muteínas y a métodos para la generación de dichas muteínas y moléculas de ácido nucleico. Además, la solicitud describe usos terapéuticos y/o de diagnóstico de estas muteínas así como composiciones que comprenden una o más de dichas muteínas.
DO2017000191A 2015-02-18 2017-08-14 Nuevas proteínas específicas para pioverdina y pioquelina DOP2017000191A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP15305242 2015-02-18

Publications (1)

Publication Number Publication Date
DOP2017000191A true DOP2017000191A (es) 2017-09-29

Family

ID=52595246

Family Applications (1)

Application Number Title Priority Date Filing Date
DO2017000191A DOP2017000191A (es) 2015-02-18 2017-08-14 Nuevas proteínas específicas para pioverdina y pioquelina

Country Status (28)

Country Link
US (8) US9884898B2 (es)
EP (1) EP3259282A1 (es)
JP (1) JP6843754B2 (es)
KR (1) KR20170116158A (es)
CN (1) CN107660211A (es)
AR (1) AR103714A1 (es)
AU (1) AU2016221816B2 (es)
BR (1) BR112017017530A2 (es)
CA (1) CA2976687A1 (es)
CL (1) CL2017002082A1 (es)
CO (1) CO2017009433A2 (es)
CR (1) CR20170425A (es)
DO (1) DOP2017000191A (es)
EA (1) EA035824B1 (es)
EC (1) ECSP17061751A (es)
GT (1) GT201700184A (es)
HK (1) HK1245293A1 (es)
IL (1) IL254013A0 (es)
MA (1) MA41072A1 (es)
MX (1) MX375049B (es)
PE (1) PE20171652A1 (es)
PH (1) PH12017501473A1 (es)
SG (1) SG11201706621SA (es)
TN (1) TN2017000348A1 (es)
TW (1) TW201636364A (es)
UY (1) UY36561A (es)
WO (1) WO2016131804A1 (es)
ZA (1) ZA201705257B (es)

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EP2510357B1 (en) 2009-12-07 2016-03-30 Pieris AG Muteins of human lipocalin 2 (lcn2, hngal) with affinity for a given target
CA2949405C (en) 2014-05-22 2023-08-01 Pieris Pharmaceuticals Gmbh Novel specific-binding polypeptides and uses thereof
RU2720688C2 (ru) 2015-01-28 2020-05-12 ПИЕРИС ФАРМАСЬЮТИКАЛС ГмбХ Новые белки, специфические в отношении ангиогенеза
AU2016221816B2 (en) * 2015-02-18 2020-07-02 Pieris Pharmaceuticals Gmbh Novel proteins specific for pyoverdine and pyochelin
AU2016258977C1 (en) 2015-05-04 2022-07-14 Pieris Pharmaceuticals Gmbh Anti-cancer fusion polypeptide
AU2016258952C1 (en) 2015-05-04 2020-12-24 Pieris Pharmaceuticals Gmbh Proteins specific for CD137
RU2754466C2 (ru) 2015-05-18 2021-09-02 ПИЕРИС ФАРМАСЬЮТИКАЛС ГмбХ Слитый полипептид с противораковой активностью
US10273275B2 (en) 2015-05-18 2019-04-30 Pieris Pharmaceuticals Gmbh Muteins of human lipocalin 2 with affinity for glypican-3 (GPC3) and methods of use thereof
EP3115371A1 (en) * 2015-07-07 2017-01-11 Sanofi Fusion molecules
CN108699162A (zh) 2015-11-30 2018-10-23 皮里斯澳大利亚有限公司 新型抗血管生成融合多肽
TW201725212A (zh) 2015-12-10 2017-07-16 第一三共股份有限公司 特異性於降鈣素基因相關胜肽的新穎蛋白
WO2018087108A1 (en) * 2016-11-09 2018-05-17 Pieris Pharmaceuticals Gmbh Proteins specific for cd137
EP3823667A4 (en) * 2018-07-19 2022-07-27 The Regents Of The University Of Colorado Methods, systems and compositions for the novel use of enterobactin to treat iron deficiency and related anemia
US20220168387A1 (en) 2019-03-29 2022-06-02 Pieris Pharmaceuticals Gmbh Inhaled administration of lipocalin muteins
CN116077621B (zh) * 2021-11-05 2026-03-24 华南农业大学 P19蛋白在调控绿脓杆菌毒力中的应用

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EP3381933B1 (en) 2008-06-24 2020-06-03 Technische Universität München Muteins of hngal and related proteins with affinity for a given target
WO2011149962A1 (en) * 2010-05-24 2011-12-01 The Trustees Of Columbia University In The City Of New York Mutant ngal proteins and uses thereof
US10526384B2 (en) 2012-11-19 2020-01-07 Pieris Pharmaceuticals Gmbh Interleukin-17A-specific and interleukin-23-specific binding polypeptides and uses thereof
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AU2016221816B2 (en) * 2015-02-18 2020-07-02 Pieris Pharmaceuticals Gmbh Novel proteins specific for pyoverdine and pyochelin
EP3115371A1 (en) 2015-07-07 2017-01-11 Sanofi Fusion molecules

Also Published As

Publication number Publication date
US20180346532A1 (en) 2018-12-06
US20180037619A1 (en) 2018-02-08
US20180086799A1 (en) 2018-03-29
TW201636364A (zh) 2016-10-16
BR112017017530A2 (pt) 2018-04-17
UY36561A (es) 2016-09-30
US10118952B2 (en) 2018-11-06
US20180037618A1 (en) 2018-02-08
CL2017002082A1 (es) 2018-04-27
US10065998B2 (en) 2018-09-04
AR103714A1 (es) 2017-05-31
CN107660211A (zh) 2018-02-02
US10329334B2 (en) 2019-06-25
US20170267734A1 (en) 2017-09-21
EA035824B1 (ru) 2020-08-17
US10072056B2 (en) 2018-09-11
AU2016221816A1 (en) 2017-10-12
CR20170425A (es) 2017-11-22
US20180371038A1 (en) 2018-12-27
US9884898B2 (en) 2018-02-06
MX2017010628A (es) 2017-12-07
MX375049B (es) 2025-03-06
ZA201705257B (en) 2019-06-26
AU2016221816B2 (en) 2020-07-02
JP6843754B2 (ja) 2021-03-17
PH12017501473A1 (en) 2018-01-29
MA41072A1 (fr) 2018-10-31
CO2017009433A2 (es) 2017-11-30
WO2016131804A1 (en) 2016-08-25
GT201700184A (es) 2018-10-24
US20180371037A1 (en) 2018-12-27
PE20171652A1 (es) 2017-11-13
SG11201706621SA (en) 2017-09-28
HK1245293A1 (zh) 2018-08-24
JP2018506979A (ja) 2018-03-15
US20180030101A1 (en) 2018-02-01
EA201791841A1 (ru) 2018-01-31
EP3259282A1 (en) 2017-12-27
IL254013A0 (en) 2017-10-31
TN2017000348A1 (en) 2019-01-16
ECSP17061751A (es) 2017-10-31
KR20170116158A (ko) 2017-10-18
CA2976687A1 (en) 2016-08-25

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