HRP20000797A2 - Combination therapy for treatment of refractory depression - Google Patents

Combination therapy for treatment of refractory depression Download PDF

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Publication number
HRP20000797A2
HRP20000797A2 HR20000797A HRP20000797A HRP20000797A2 HR P20000797 A2 HRP20000797 A2 HR P20000797A2 HR 20000797 A HR20000797 A HR 20000797A HR P20000797 A HRP20000797 A HR P20000797A HR P20000797 A2 HRP20000797 A2 HR P20000797A2
Authority
HR
Croatia
Prior art keywords
treatment
component
effective amount
depression
combination
Prior art date
Application number
HR20000797A
Other languages
English (en)
Croatian (hr)
Inventor
Gary Dennis Tollefson
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of HRP20000797A2 publication Critical patent/HRP20000797A2/hr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Percussion Or Vibration Massage (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Compositions Of Oxide Ceramics (AREA)
HR20000797A 1998-05-22 1999-05-21 Combination therapy for treatment of refractory depression HRP20000797A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8644498P 1998-05-22 1998-05-22
PCT/US1999/011276 WO1999061027A1 (fr) 1998-05-22 1999-05-21 Therapie combinee de traitement de la depression resistante

Publications (1)

Publication Number Publication Date
HRP20000797A2 true HRP20000797A2 (en) 2001-10-31

Family

ID=22198612

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20000797A HRP20000797A2 (en) 1998-05-22 1999-05-21 Combination therapy for treatment of refractory depression

Country Status (24)

Country Link
EP (1) EP0958824A3 (fr)
JP (1) JP2002516282A (fr)
KR (1) KR20010043730A (fr)
CN (1) CN1154496C (fr)
AU (1) AU761510B2 (fr)
BR (1) BR9911049A (fr)
CA (1) CA2332814C (fr)
CZ (1) CZ20004279A3 (fr)
EA (1) EA004539B1 (fr)
HK (1) HK1040055B (fr)
HR (1) HRP20000797A2 (fr)
HU (1) HUP0101901A3 (fr)
ID (1) ID26861A (fr)
IL (1) IL139592A (fr)
MY (1) MY127938A (fr)
NO (1) NO20005885L (fr)
NZ (1) NZ507980A (fr)
PL (1) PL344331A1 (fr)
SK (1) SK17512000A3 (fr)
TR (1) TR200003443T2 (fr)
TW (1) TWI226829B (fr)
UA (1) UA78181C2 (fr)
WO (1) WO1999061027A1 (fr)
ZA (1) ZA200006815B (fr)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1133299A1 (fr) * 1998-11-23 2001-09-19 Sepracor Inc. Compositions a base de 2-hydroxymethylolanzapine et leurs utilisations
EP1396267A3 (fr) * 1999-12-06 2004-04-21 H. Lundbeck A/S Combinaison d'un inhibiteur du recaptage de la serotonine et d'un antagoniste, d'un agoniste inverse ou d'un agoniste partiel de 5-ht
UA77650C2 (en) * 1999-12-06 2007-01-15 Lundbeck & Co As H Use of serotonin reuptake inhibitor in combination with deramcyclane
CA2431041A1 (fr) * 2001-01-02 2002-07-11 Pharmacia & Upjohn Company Nouvelles combinaisons medicamenteuses d'inhibiteurs de recaptage de la norepinehrine et d'agents neuroleptiques
CA2529857A1 (fr) 2002-07-30 2004-02-05 Peter Migaly Combinaison de therapie pour la depression, la prevention du suicide et divers troubles medicaux et psychiatriques
GB0229583D0 (en) * 2002-12-19 2003-01-22 Cipla Ltd A process for preparing duloxetine and intermediates for use therein
KR100842694B1 (ko) 2002-12-27 2008-07-01 오쓰까 세이야꾸 가부시키가이샤 기분 장애 치료용 카르보스티릴 유도체 및 세로토닌 재흡수억제제
AR042806A1 (es) 2002-12-27 2005-07-06 Otsuka Pharma Co Ltd Combinacion de derivados de carboestirilo e inhibidores de la reabsorcion de serotonina para el tratamiento de trastornos del animo
FR2851163B1 (fr) * 2003-02-14 2007-04-27 Utilisation de l'enantiomere dextrogyre du milnacipran pour la preparation d'un medicament
WO2005023243A1 (fr) * 2003-09-04 2005-03-17 H. Lundbeck A/S Combinaison d'un inhibiteur de recaptage de serotonine et de loxapine
ES2319539T3 (es) 2003-09-17 2009-05-08 Janssen Pharmaceutica Nv Compuestos heterociclicos condensados como moduladores del receptor de serotonina.
EP1713486A4 (fr) * 2003-12-02 2009-04-29 Sheldon Leslie James Therapie combinee pour le traitement de la demence, la depression et l'apathie
WO2005056056A2 (fr) * 2003-12-15 2005-06-23 H. Lundbeck A/S Combinaison d'un inhibiteur de reabsorption de la serotonine et d'un antagoniste du recepteur de l'histamine 3, agoniste inverse ou partiel
US7598255B2 (en) 2005-08-04 2009-10-06 Janssen Pharmaceutica Nv Pyrimidine compounds as serotonin receptor modulators
EP2275095A3 (fr) * 2005-08-26 2011-08-17 Braincells, Inc. Neurogenese par modulation des recepteurs muscariniques
PL2044043T5 (pl) 2006-06-16 2022-05-02 H. Lundbeck A/S Bromowodorek 1-[2-(2,4-dimetylofenylosulfanylo)fenylo]piperazyny jako związek o połączonym działaniu wychwytu zwrotnego serotoniny i działaniu na 5-ht3 i 5-ht1a do leczenia upośledzenia funckji poznawczych
PL2120878T3 (pl) * 2007-02-09 2015-01-30 Alphapharm Pty Ltd Postać dawkowania zawierająca dwa czynne składniki farmaceutyczne o różnych postaciach fizycznych
TWI432194B (zh) * 2007-03-20 2014-04-01 Lundbeck & Co As H ４-〔２-（４-甲基苯硫基）苯基〕哌啶之新穎治療用途
US20140206667A1 (en) 2012-11-14 2014-07-24 Michela Gallagher Methods and compositions for treating schizophrenia
CN105769875A (zh) * 2014-12-22 2016-07-20 扬子江药业集团上海海尼药业有限公司 复方奥氮平盐酸氟西汀胶囊的制备方法
CN108938645A (zh) * 2018-08-24 2018-12-07 山西医科大学第医院 一种抗精神病药物组合物
CN111084778B (zh) * 2019-12-31 2022-06-24 北京鑫开元医药科技有限公司 一种奥氮平盐酸氟西汀胶囊及其制备方法
CN114569566A (zh) * 2020-12-02 2022-06-03 四川科瑞德制药股份有限公司 一种盐酸米那普仑制剂的制备方法
ES3054324A1 (es) * 2024-07-12 2026-02-02 Univ Malaga Galanina (1-15) y Fluoxetina en el tratamiento de la depresión resistente al tratamiento

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU8072691A (en) * 1990-06-28 1992-01-23 Beecham Group Plc Pharmaceutical preparations
FR2716680B1 (fr) * 1994-02-25 1996-04-05 Adir Nouveaux dérivés de benzodioxane, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
HUP9903679A3 (en) * 1996-03-11 2001-10-29 Lilly Co Eli Use of olanzapine for the preparation of pharmaceutical compositions treating bipolar disorder
UA48219C2 (uk) * 1996-03-25 2002-08-15 Елі Ліллі Енд Компані Композиція для вгамування болю (варіанти) та спосіб вгамування болю
ZA977967B (en) * 1996-09-23 1999-03-04 Lilly Co Eli Combination therapy for treatment of psychoses

Also Published As

Publication number Publication date
MY127938A (en) 2007-01-31
EA200001218A1 (ru) 2001-06-25
ID26861A (id) 2001-02-15
WO1999061027A1 (fr) 1999-12-02
EA004539B1 (ru) 2004-06-24
NZ507980A (en) 2003-10-31
HK1040055A1 (en) 2002-05-24
SK17512000A3 (sk) 2002-02-05
IL139592A (en) 2005-08-31
CZ20004279A3 (cs) 2001-09-12
PL344331A1 (en) 2001-11-05
UA78181C2 (en) 2007-03-15
CA2332814A1 (fr) 1999-12-02
KR20010043730A (ko) 2001-05-25
JP2002516282A (ja) 2002-06-04
CN1311681A (zh) 2001-09-05
EP0958824A2 (fr) 1999-11-24
AU761510B2 (en) 2003-06-05
HUP0101901A2 (hu) 2001-11-28
IL139592A0 (en) 2002-02-10
CN1154496C (zh) 2004-06-23
BR9911049A (pt) 2001-02-06
AU4008699A (en) 1999-12-13
HUP0101901A3 (en) 2002-06-28
TWI226829B (en) 2005-01-21
EP0958824A3 (fr) 1999-12-01
ZA200006815B (en) 2002-01-14
HK1040055B (zh) 2005-04-01
CA2332814C (fr) 2008-11-04
TR200003443T2 (tr) 2001-03-21
NO20005885D0 (no) 2000-11-21
NO20005885L (no) 2001-01-17

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