HRP20010868A2 - Aminoalkyl substituted (benzodioxan, benzofuran or benzopyran) derivatives - Google Patents

Aminoalkyl substituted (benzodioxan, benzofuran or benzopyran) derivatives Download PDF

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Publication number
HRP20010868A2
HRP20010868A2 HR20010868A HRP20010868A HRP20010868A2 HR P20010868 A2 HRP20010868 A2 HR P20010868A2 HR 20010868 A HR20010868 A HR 20010868A HR P20010868 A HRP20010868 A HR P20010868A HR P20010868 A2 HRP20010868 A2 HR P20010868A2
Authority
HR
Croatia
Prior art keywords
formula
alkyl
hydrogen
hydroxy
alkyloxycarbonyloxy
Prior art date
Application number
HR20010868A
Other languages
English (en)
Croatian (hr)
Inventor
Kristof Van Emelen
Marcel Frans Leopold De Bruyn
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of HRP20010868A2 publication Critical patent/HRP20010868A2/hr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pyrane Compounds (AREA)
HR20010868A 1999-06-02 2000-05-23 Aminoalkyl substituted (benzodioxan, benzofuran or benzopyran) derivatives HRP20010868A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99201747 1999-06-02
PCT/EP2000/004746 WO2000075136A1 (en) 1999-06-02 2000-05-23 Aminoalkyl substituted (benzodioxan, benzofuran or benzopyran) derivatives

Publications (1)

Publication Number Publication Date
HRP20010868A2 true HRP20010868A2 (en) 2003-04-30

Family

ID=8240260

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20010868A HRP20010868A2 (en) 1999-06-02 2000-05-23 Aminoalkyl substituted (benzodioxan, benzofuran or benzopyran) derivatives

Country Status (33)

Country Link
US (2) US6864273B1 (pt)
EP (1) EP1187829B1 (pt)
JP (1) JP2003501427A (pt)
KR (1) KR100699512B1 (pt)
CN (1) CN1150191C (pt)
AR (1) AR033334A1 (pt)
AT (1) ATE256125T1 (pt)
AU (1) AU773773B2 (pt)
BG (1) BG65269B1 (pt)
BR (1) BR0011237A (pt)
CA (1) CA2374902C (pt)
CZ (1) CZ20014177A3 (pt)
DE (1) DE60007124T2 (pt)
DK (1) DK1187829T3 (pt)
EA (1) EA004645B1 (pt)
EE (1) EE04780B1 (pt)
ES (1) ES2212774T3 (pt)
HR (1) HRP20010868A2 (pt)
HU (1) HUP0201404A3 (pt)
IL (2) IL146840A0 (pt)
MX (1) MXPA01012330A (pt)
MY (1) MY120618A (pt)
NO (1) NO319953B1 (pt)
NZ (1) NZ514993A (pt)
PL (1) PL198552B1 (pt)
PT (1) PT1187829E (pt)
SI (1) SI1187829T1 (pt)
SK (1) SK285619B6 (pt)
TR (1) TR200103430T2 (pt)
TW (1) TWI289559B (pt)
UA (1) UA73122C2 (pt)
WO (1) WO2000075136A1 (pt)
ZA (1) ZA200109860B (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK286159B6 (sk) 1999-06-02 2008-04-07 Janssen Pharmaceutica N. V. Benzodioxánový, benzofuránový alebo benzopyránovýderivát, spôsob jeho prípravy, tento derivát na použitie ako liečivo, farmaceutická kompozícia obsahujúca tento derivát a spôsob jej prípravy
JO2352B1 (en) 2000-06-22 2006-12-12 جانسين فارماسيوتيكا ان. في Compounds for the treatment of non-adaptation of the bottom of the uterus
JO2654B1 (en) 2000-09-04 2012-06-17 شركة جانسين فارماسوتيكا ان. في Multiple aryl caroxa amides are useful as lipid - lowering agents
JO2409B1 (en) 2000-11-21 2007-06-17 شركة جانسين فارماسوتيكا ان. في Second-phenyl carboxy amides are useful as lipid-lowering agents
JP5281226B2 (ja) * 2002-04-08 2013-09-04 ゼリア新薬工業株式会社 胃食物受容能障害治療薬
JP2008530229A (ja) 2005-02-17 2008-08-07 ワイス シクロアルキル縮合インドール、ベンゾチオフェン、ベンゾフランおよびインデン誘導体
CN103917529B (zh) 2011-11-11 2016-08-17 辉瑞大药厂 2-硫代嘧啶酮类
AU2016257179A1 (en) 2015-05-05 2017-11-02 Pfizer Inc. 2-thiopyrimidinones

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3910930A (en) 1973-01-04 1975-10-07 Janssen Pharmaceutica Nv 1-{55 1-{8 2-(1,4-Benzodioxan-2-yl)-2-hydroxyethyl{9 -4-piperidyl{56 -2-benzimidazolinones
US3929801A (en) 1973-11-20 1975-12-30 Janssen Pharmaceutica Nv 2-Benzimidazolinones
GR71865B (pt) 1978-03-20 1983-07-07 Ciba Geigy
DE2852945A1 (de) 1978-12-07 1980-06-26 Boehringer Sohn Ingelheim Benzodioxanyl-hydroxyaethylpiperidyl- imidazolidinone, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
US4329348A (en) 1979-02-26 1982-05-11 Ciba-Geigy Corporation N-Oxacyclic-alkylpiperidines as psychostimulants
DE3124366A1 (de) 1981-06-20 1982-12-30 Hoechst Ag, 6000 Frankfurt N-oxacyclyl-alkylpiperidin-derivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische praeparate und deren verwendung
FR2533584B1 (fr) 1982-09-28 1986-03-21 Pasteur Institut Procede de detection du pouvoir mutagene de substances, susceptibles d'induire la deterioration d'adn cellulaires, mettant en jeu la production d'une reponse sos
DE3901814A1 (de) 1988-07-28 1990-02-01 Bayer Ag Substituierte aminomethylzetraline sowie ihre heterocyclischen analoga
DE4140540A1 (de) 1991-12-09 1993-06-17 Bayer Ag Neue azaheterocyclylmethyl-chromane
SI9300097B (en) * 1992-02-27 2001-12-31 Janssen Pharmaceutica Nv (benzodioxan, benzofuran or benzopyran) alkylamino) alkyl substituted guanidines
DE4319038A1 (de) * 1993-06-08 1994-12-15 Bayer Ag Verwendung von teilweise bekannten substituierten Chromanen als Arzneimittel, neue Wirkstoffe und Verfahren zu ihrer Herstellung
ES2212797T3 (es) 1993-08-19 2004-08-01 Janssen Pharmaceutica N.V. Derivados de dihidrobenzopirano vasoconstrictores.
US5541199A (en) 1995-06-02 1996-07-30 American Home Products Corporation Chroman-2-ylmethylamino derivatives
FR2744451B1 (fr) 1996-02-01 1998-04-24 Pf Medicament Nouvelles imidazolidinones, pyrimidinones, et 1,3-diazepin-2 -ones, leur preparation et leurs applications en therapeutique
US6133277A (en) * 1997-12-05 2000-10-17 Janssen Pharmaceutica N.V. (Benzodioxan, benzofuran or benzopyran) derivatives having fundic relaxation properties
SK286159B6 (sk) 1999-06-02 2008-04-07 Janssen Pharmaceutica N. V. Benzodioxánový, benzofuránový alebo benzopyránovýderivát, spôsob jeho prípravy, tento derivát na použitie ako liečivo, farmaceutická kompozícia obsahujúca tento derivát a spôsob jej prípravy
JO2352B1 (en) 2000-06-22 2006-12-12 جانسين فارماسيوتيكا ان. في Compounds for the treatment of non-adaptation of the bottom of the uterus

Also Published As

Publication number Publication date
TR200103430T2 (tr) 2002-06-21
EE200100639A (et) 2003-02-17
JP2003501427A (ja) 2003-01-14
US7273862B2 (en) 2007-09-25
CA2374902A1 (en) 2000-12-14
BG65269B1 (bg) 2007-11-30
IL146840A (en) 2006-12-10
WO2000075136A1 (en) 2000-12-14
ATE256125T1 (de) 2003-12-15
NO20015903L (no) 2001-12-03
KR100699512B1 (ko) 2007-03-26
PL198552B1 (pl) 2008-06-30
DE60007124T2 (de) 2004-09-23
BR0011237A (pt) 2002-03-05
HUP0201404A2 (en) 2002-08-28
EA004645B1 (ru) 2004-06-24
CZ20014177A3 (cs) 2002-05-15
EP1187829A1 (en) 2002-03-20
TWI289559B (en) 2007-11-11
CA2374902C (en) 2009-09-15
ZA200109860B (en) 2003-05-28
AR033334A1 (es) 2003-12-17
CN1353707A (zh) 2002-06-12
PL352112A1 (en) 2003-07-28
IL146840A0 (en) 2002-07-25
MY120618A (en) 2005-11-30
ES2212774T3 (es) 2004-08-01
EA200101236A1 (ru) 2002-08-29
UA73122C2 (en) 2005-06-15
CN1150191C (zh) 2004-05-19
MXPA01012330A (es) 2002-07-30
DE60007124D1 (de) 2004-01-22
SK17032001A3 (sk) 2002-07-02
US20050096378A1 (en) 2005-05-05
US6864273B1 (en) 2005-03-08
BG106156A (en) 2002-05-31
SK285619B6 (sk) 2007-05-03
AU5525600A (en) 2000-12-28
KR20010110806A (ko) 2001-12-13
EE04780B1 (et) 2007-02-15
NZ514993A (en) 2003-05-30
NO20015903D0 (no) 2001-12-03
SI1187829T1 (en) 2004-04-30
DK1187829T3 (da) 2004-04-13
PT1187829E (pt) 2004-04-30
HUP0201404A3 (en) 2005-02-28
AU773773B2 (en) 2004-06-03
EP1187829B1 (en) 2003-12-10
NO319953B1 (no) 2005-10-03

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