HRP20031068B1 - Chloromethylation of thiophene - Google Patents

Chloromethylation of thiophene

Info

Publication number: HRP20031068B1
Authority: HR; Croatia
Prior art keywords: chloromethylation; thiophene; ketone; compound; formula
Prior art date: 2001-05-22

Application number

HR20031068A

Other languages

English (en)

Croatian (hr)

Inventor

Aradi M�ty�s

Bakos Ferenc

Dombr�dy Zsolt

Gaj�ry Antal

Gy�ngy�si Istv�n

Kov�cs Ferenc

Major Andrea

M�t�n� T�r�k Erika

P�rk�nyi Zsolt

Schultz L�szl�

Supic Attila

Szab� S�ndor

Szalay Erzs�bet

Ugrics J�zsef

Zsiga J�zsef

Original Assignee

Sanofi-Aventis

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-05-22

Filing date

2002-05-16

Publication date

2011-12-31

2002-05-16 Application filed by Sanofi-Aventis filed Critical Sanofi-Aventis

2004-04-30 Publication of HRP20031068A2 publication Critical patent/HRP20031068A2/xx

2011-12-31 Publication of HRP20031068B1 publication Critical patent/HRP20031068B1/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/12—Radicals substituted by halogen atoms or nitro or nitroso radicals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Control Of Charge By Means Of Generators (AREA)

HR20031068A 2001-05-22 2002-05-16 Chloromethylation of thiophene HRP20031068B1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
HU0102118A HU0102118D0 (en)	2001-05-22	2001-05-22	Process for chloromethylation
PCT/HU2002/000042 WO2002094806A1 (en)	2001-05-22	2002-05-16	Chloromethylation of thiophene

Publications (2)

Publication Number	Publication Date
HRP20031068A2 HRP20031068A2 (en)	2004-04-30
HRP20031068B1 true HRP20031068B1 (en)	2011-12-31

Family

ID=89979350

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HR20031068A HRP20031068B1 (en)	2001-05-22	2002-05-16	Chloromethylation of thiophene

Country Status (20)

Country	Link
US (1)	US7462725B2 (de)
EP (1)	EP1392672B1 (de)
JP (1)	JP4467890B2 (de)
KR (1)	KR100859386B1 (de)
CN (1)	CN1260224C (de)
AT (1)	ATE294790T1 (de)
BR (1)	BRPI0209874B1 (de)
CA (1)	CA2447440C (de)
CZ (1)	CZ301166B6 (de)
DE (1)	DE60204014T2 (de)
DK (1)	DK1392672T3 (de)
ES (1)	ES2240738T3 (de)
HR (1)	HRP20031068B1 (de)
HU (1)	HU0102118D0 (de)
MX (1)	MXPA03010594A (de)
PL (1)	PL210713B1 (de)
PT (1)	PT1392672E (de)
SI (1)	SI1392672T1 (de)
SK (1)	SK285681B6 (de)
WO (1)	WO2002094806A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN104513225A (zh) *	2013-10-08	2015-04-15	华东师范大学	2-噻吩乙腈的制备方法
CN103880741A (zh) *	2014-02-28	2014-06-25	安徽国星生物化学有限公司	一种2-氯甲基-3，5-二甲基-4-烷氧基吡啶-n-氧化物的制备方法
CN103992302A (zh) *	2014-06-16	2014-08-20	商丘凯瑞达化工有限公司	2-噻吩乙酸合成工艺
CN104327040A (zh) *	2014-10-11	2015-02-04	华东师范大学	一种2-噻吩乙酸的合成方法
US10450512B2 (en) *	2016-02-10	2019-10-22	Primus Green Energy Inc.	Single-loop octane enrichment
CN113896709B (zh) *	2021-11-22	2023-02-28	南京一苇医药科技有限公司	一种苯并噻吩-3-乙酸的合成方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2527680A (en) *	1945-06-21	1950-10-31	Monsanto Chemicals	Alpha thenyl chloride from hydrogen chloride-formaldehyde solution and thiophene
US4501903A (en) *	1983-07-05	1985-02-26	Stauffer Chemical Company	Chloromethylation process

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB639438A (en) *	1948-02-25	1950-06-28	Ici Ltd	Preparation of organic nitriles
FR2608607B1 (fr) *	1986-12-23	1989-04-28	Sanofi Sa	Procede de preparation de thienylethylamines et dithienylethylamines ainsi obtenues
PL158225B1 (en) *	1989-06-09	1992-08-31		Method for manufacturing 2-chlormethylthiopen

2001
- 2001-05-22 HU HU0102118A patent/HU0102118D0/hu unknown
2002
- 2002-05-16 SK SK1354-2003A patent/SK285681B6/sk not_active IP Right Cessation
- 2002-05-16 DE DE60204014T patent/DE60204014T2/de not_active Expired - Lifetime
- 2002-05-16 AT AT02727810T patent/ATE294790T1/de active
- 2002-05-16 US US10/478,238 patent/US7462725B2/en not_active Expired - Lifetime
- 2002-05-16 SI SI200230143T patent/SI1392672T1/xx unknown
- 2002-05-16 DK DK02727810T patent/DK1392672T3/da active
- 2002-05-16 BR BRPI0209874A patent/BRPI0209874B1/pt not_active IP Right Cessation
- 2002-05-16 MX MXPA03010594A patent/MXPA03010594A/es active IP Right Grant
- 2002-05-16 PL PL363923A patent/PL210713B1/pl unknown
- 2002-05-16 CZ CZ20032973A patent/CZ301166B6/cs not_active IP Right Cessation
- 2002-05-16 WO PCT/HU2002/000042 patent/WO2002094806A1/en not_active Ceased
- 2002-05-16 CN CNB028103882A patent/CN1260224C/zh not_active Expired - Lifetime
- 2002-05-16 EP EP02727810A patent/EP1392672B1/de not_active Expired - Lifetime
- 2002-05-16 HR HR20031068A patent/HRP20031068B1/xx not_active IP Right Cessation
- 2002-05-16 PT PT02727810T patent/PT1392672E/pt unknown
- 2002-05-16 CA CA2447440A patent/CA2447440C/en not_active Expired - Lifetime
- 2002-05-16 KR KR1020037015114A patent/KR100859386B1/ko not_active Expired - Fee Related
- 2002-05-16 ES ES02727810T patent/ES2240738T3/es not_active Expired - Lifetime
- 2002-05-16 JP JP2002591479A patent/JP4467890B2/ja not_active Expired - Fee Related

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2527680A (en) *	1945-06-21	1950-10-31	Monsanto Chemicals	Alpha thenyl chloride from hydrogen chloride-formaldehyde solution and thiophene
US4501903A (en) *	1983-07-05	1985-02-26	Stauffer Chemical Company	Chloromethylation process

Also Published As

Publication number	Publication date
DE60204014T2 (de)	2006-02-02
PL363923A1 (en)	2004-11-29
CA2447440C (en)	2010-10-19
WO2002094806A1 (en)	2002-11-28
CN1511148A (zh)	2004-07-07
EP1392672A1 (de)	2004-03-03
HRP20031068A2 (en)	2004-04-30
PT1392672E (pt)	2005-08-31
ATE294790T1 (de)	2005-05-15
US7462725B2 (en)	2008-12-09
BRPI0209874B1 (pt)	2016-03-22
BR0209874A (pt)	2004-06-08
JP2004532247A (ja)	2004-10-21
KR20040018373A (ko)	2004-03-03
HU0102118D0 (en)	2001-07-30
PL210713B1 (pl)	2012-02-29
SK285681B6 (sk)	2007-06-07
CZ301166B6 (cs)	2009-11-25
DK1392672T3 (da)	2005-08-29
JP4467890B2 (ja)	2010-05-26
EP1392672B1 (de)	2005-05-04
US20060161008A1 (en)	2006-07-20
SK13542003A3 (sk)	2004-07-07
DE60204014D1 (de)	2005-06-09
ES2240738T3 (es)	2005-10-16
CZ20032973A3 (en)	2004-03-17
CN1260224C (zh)	2006-06-21
SI1392672T1 (en)	2005-10-31
CA2447440A1 (en)	2002-11-28
MXPA03010594A (es)	2004-04-02
KR100859386B1 (ko)	2008-09-22

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Legal Events

Date	Code	Title	Description
2004-04-30	A1OB	Publication of a patent application
2004-09-23	ARAI	Request for the grant of a patent on the basis of the submitted results of a substantive examination of a patent application
2005-02-21	PNAN	Change of the applicant name, address/residence	Owner name: SANOFI-AVENTIS, FR
2011-12-31	B1PR	Patent granted
2019-04-19	ODRP	Renewal fee for the maintenance of a patent	Payment date: 20190401 Year of fee payment: 18
2020-05-29	ODRP	Renewal fee for the maintenance of a patent	Payment date: 20200331 Year of fee payment: 19
2021-12-08	PBON	Lapse due to non-payment of renewal fee	Effective date: 20210516