HRP20040067A2 - Pharmaceutical compositions of amlodipine and atorvastatin - Google Patents

Pharmaceutical compositions of amlodipine and atorvastatin

Info

Publication number
HRP20040067A2
HRP20040067A2 HR20040067A HRP20040067A HRP20040067A2 HR P20040067 A2 HRP20040067 A2 HR P20040067A2 HR 20040067 A HR20040067 A HR 20040067A HR P20040067 A HRP20040067 A HR P20040067A HR P20040067 A2 HRP20040067 A2 HR P20040067A2
Authority
HR
Croatia
Prior art keywords
amlodipine
atorvastatin
pharmaceutical compositions
pharmaceutical
compositions
Prior art date
Application number
HR20040067A
Other languages
English (en)
Inventor
Alani Laman
Ulla Khan Sadath
Michael Macnell Thomas
Abdul-Hussain Muhammad Nouman
Original Assignee
Warner-Lambert Company Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner-Lambert Company Llc filed Critical Warner-Lambert Company Llc
Publication of HRP20040067A2 publication Critical patent/HRP20040067A2/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4418Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2009Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/401Proline; Derivatives thereof, e.g. captopril
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/44221,4-Dihydropyridines, e.g. nifedipine, nicardipine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1611Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Inorganic Chemistry (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
HR20040067A 2001-07-31 2002-07-29 Pharmaceutical compositions of amlodipine and atorvastatin HRP20040067A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30913301P 2001-07-31 2001-07-31
PCT/IB2002/002988 WO2003011283A1 (en) 2001-07-31 2002-07-29 Pharmaceutical compositions of amlodipine and atorvastatin

Publications (1)

Publication Number Publication Date
HRP20040067A2 true HRP20040067A2 (en) 2005-02-28

Family

ID=23196829

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20040067A HRP20040067A2 (en) 2001-07-31 2002-07-29 Pharmaceutical compositions of amlodipine and atorvastatin

Country Status (47)

Country Link
US (2) US20030114497A1 (de)
EP (2) EP1852116A1 (de)
JP (3) JP4020863B2 (de)
KR (2) KR100674762B1 (de)
CN (2) CN1617717A (de)
AP (1) AP1745A (de)
AR (1) AR034925A1 (de)
AT (1) ATE385793T1 (de)
AU (1) AU2002355680B2 (de)
BR (1) BR0211548A (de)
CA (1) CA2444554C (de)
CO (1) CO5540287A2 (de)
CR (1) CR7219A (de)
CY (1) CY1107245T1 (de)
DE (1) DE60225014T2 (de)
DK (1) DK1411923T3 (de)
DO (1) DOP2002000445A (de)
EA (1) EA006998B1 (de)
EC (1) ECSP044965A (de)
ES (1) ES2298381T3 (de)
GE (1) GEP20063926B (de)
GT (1) GT200200158A (de)
HN (1) HN2002000198A (de)
HR (1) HRP20040067A2 (de)
HU (1) HUP0401569A2 (de)
IL (1) IL159440A0 (de)
IS (1) IS7089A (de)
MA (1) MA27052A1 (de)
MX (1) MXPA04000270A (de)
MY (1) MY137519A (de)
NI (1) NI200200095A (de)
NO (1) NO20040405L (de)
NZ (1) NZ530247A (de)
OA (1) OA13300A (de)
PA (1) PA8551701A1 (de)
PE (1) PE20030324A1 (de)
PL (1) PL368519A1 (de)
PT (1) PT1411923E (de)
PY (1) PY0218256A (de)
RS (1) RS5304A (de)
SG (1) SG143982A1 (de)
SV (1) SV2003001189A (de)
TN (1) TNSN04022A1 (de)
UA (1) UA79750C2 (de)
UY (1) UY27402A1 (de)
WO (1) WO2003011283A1 (de)
ZA (1) ZA200400659B (de)

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EP1833466A1 (de) * 2004-12-28 2007-09-19 Ranbaxy Laboratories Limited Verfahren zur herstelulng von stabilen pharmazeutischen soliden dosierformen von atorvastatin und amlodipin
EP1863457A2 (de) * 2005-03-15 2007-12-12 Lupin Ltd. Pharmazeutische zusammensetzungen von amlodipin und benazepril
JP5330825B2 (ja) * 2006-03-29 2013-10-30 興和株式会社 トリグリセリド低下剤及び高インスリン血症改善剤
DE102006033723A1 (de) * 2006-07-21 2008-01-24 Bayer Technology Services Gmbh Formulierungen von Multikompartimenten-Granulaten für Wirkstoffe
KR100793321B1 (ko) * 2006-11-29 2008-01-11 사회복지법인 삼성생명공익재단 후각장애 치료 및 예방용 조성물
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KR20140028971A (ko) 2012-08-31 2014-03-10 한미약품 주식회사 아토바스타틴, 이르베살탄 및 탄산마그네슘을 포함하는 이층정 복합제제
KR101771766B1 (ko) * 2013-12-30 2017-08-28 알보젠코리아 주식회사 안지오텐신-Ⅱ 수용체 차단제 및 HMG-CoA 환원효소 저해제를 포함하는 약제학적 복합제제
US10350171B2 (en) 2017-07-06 2019-07-16 Dexcel Ltd. Celecoxib and amlodipine formulation and method of making the same
CN109180701A (zh) * 2018-09-07 2019-01-11 中国药科大学 一种化合物2016a0c1药物组合物的共无定形物
KR102042626B1 (ko) 2019-06-26 2019-11-11 한미약품 주식회사 이베살탄 및 HMG-CoA 환원효소 억제제를 포함하는 약제학적 캡슐 복합제제
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Also Published As

Publication number Publication date
AR034925A1 (es) 2004-03-24
RS5304A (sr) 2006-10-27
DK1411923T3 (da) 2009-01-05
CN101185646A (zh) 2008-05-28
MA27052A1 (fr) 2004-12-20
PA8551701A1 (es) 2003-02-14
EA200400028A1 (ru) 2004-08-26
EA006998B1 (ru) 2006-06-30
JP2007153908A (ja) 2007-06-21
DE60225014D1 (de) 2008-03-27
JP4020863B2 (ja) 2007-12-12
MXPA04000270A (es) 2004-05-04
JP2005501051A (ja) 2005-01-13
PE20030324A1 (es) 2003-04-03
NZ530247A (en) 2006-06-30
OA13300A (en) 2007-04-13
SG143982A1 (en) 2008-07-29
HN2002000198A (es) 2005-10-20
ZA200400659B (en) 2005-04-28
PT1411923E (pt) 2008-04-02
JP2007314566A (ja) 2007-12-06
IL159440A0 (en) 2004-06-01
NI200200095A (es) 2004-06-07
CA2444554A1 (en) 2003-02-13
ECSP044965A (es) 2004-03-23
UY27402A1 (es) 2003-02-28
TNSN04022A1 (fr) 2006-06-01
SV2003001189A (es) 2003-03-18
KR20040032148A (ko) 2004-04-14
CA2444554C (en) 2007-09-04
GEP20063926B (en) 2006-09-25
KR20060054495A (ko) 2006-05-22
BR0211548A (pt) 2004-07-13
AP1745A (en) 2007-05-30
CN1617717A (zh) 2005-05-18
AU2002355680B2 (en) 2007-11-15
AP2004002963A0 (en) 2004-03-31
DE60225014T2 (de) 2008-06-12
UA79750C2 (en) 2007-07-25
EP1411923B1 (de) 2008-02-13
DOP2002000445A (es) 2003-01-31
US20050107446A1 (en) 2005-05-19
CR7219A (es) 2004-03-24
US20030114497A1 (en) 2003-06-19
CO5540287A2 (es) 2005-07-29
PL368519A1 (pl) 2005-04-04
GT200200158A (es) 2003-05-15
EP1411923A1 (de) 2004-04-28
EP1852116A1 (de) 2007-11-07
IS7089A (is) 2003-12-22
HUP0401569A2 (hu) 2004-12-28
KR100674762B1 (ko) 2007-01-25
MY137519A (en) 2009-02-27
PY0218256A (es) 2004-03-01
WO2003011283A1 (en) 2003-02-13
ATE385793T1 (de) 2008-03-15
ES2298381T3 (es) 2008-05-16
CY1107245T1 (el) 2012-11-21
NO20040405L (no) 2004-03-08

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