HRP20040194A2 - GLYCINE-SUBSTITUTED THIENO [2,3-d] PYRIMIDINES WITH COMBINED LH AND FSH AGONISTIC ACTIVITY - Google Patents

GLYCINE-SUBSTITUTED THIENO [2,3-d] PYRIMIDINES WITH COMBINED LH AND FSH AGONISTIC ACTIVITY Download PDF

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Publication number
HRP20040194A2
HRP20040194A2 HR20040194A HRP20040194A HRP20040194A2 HR P20040194 A2 HRP20040194 A2 HR P20040194A2 HR 20040194 A HR20040194 A HR 20040194A HR P20040194 A HRP20040194 A HR P20040194A HR P20040194 A2 HRP20040194 A2 HR P20040194A2
Authority
HR
Croatia
Prior art keywords
amino
pyrimidine
thieno
mixture
phenyl
Prior art date
Application number
HR20040194A
Other languages
English (en)
Croatian (hr)
Inventor
Robert Gerard Jules Ma Hanssen
Cornelis Marius Timmers
Jan Kelder
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Publication of HRP20040194A2 publication Critical patent/HRP20040194A2/hr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A61P5/08—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH for decreasing, blocking or antagonising the activity of the anterior pituitary hormones

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HR20040194A 2001-09-04 2002-08-29 GLYCINE-SUBSTITUTED THIENO [2,3-d] PYRIMIDINES WITH COMBINED LH AND FSH AGONISTIC ACTIVITY HRP20040194A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01203328 2001-09-04
PCT/EP2002/009648 WO2003020727A1 (en) 2001-09-04 2002-08-29 GLYCINE-SUBSTITUTED THIENO [2,3-d]PYRIMIDINES WITH COMBINED LH AND FSH AGONISTIC ACTIVITY

Publications (1)

Publication Number Publication Date
HRP20040194A2 true HRP20040194A2 (en) 2004-08-31

Family

ID=8180877

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20040194A HRP20040194A2 (en) 2001-09-04 2002-08-29 GLYCINE-SUBSTITUTED THIENO [2,3-d] PYRIMIDINES WITH COMBINED LH AND FSH AGONISTIC ACTIVITY

Country Status (27)

Country Link
US (1) US7375109B2 (de)
EP (1) EP1427734B1 (de)
JP (1) JP4263094B2 (de)
KR (1) KR100891630B1 (de)
CN (1) CN1261437C (de)
AR (1) AR036408A1 (de)
AT (1) ATE309251T1 (de)
AU (1) AU2002333750B2 (de)
BR (1) BR0212173A (de)
CA (1) CA2457212C (de)
CY (1) CY1106052T1 (de)
DE (1) DE60207280T2 (de)
DK (1) DK1427734T3 (de)
EC (1) ECSP044990A (de)
ES (1) ES2252540T3 (de)
HR (1) HRP20040194A2 (de)
HU (1) HUP0401443A3 (de)
IL (2) IL160194A0 (de)
IS (1) IS2419B (de)
MX (1) MXPA04002046A (de)
NO (1) NO328792B1 (de)
NZ (1) NZ531375A (de)
PE (1) PE20030467A1 (de)
PL (1) PL368388A1 (de)
RU (1) RU2294331C2 (de)
WO (1) WO2003020727A1 (de)
ZA (1) ZA200401459B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6890923B2 (en) * 2002-12-16 2005-05-10 Astrazeneca Ab Compounds
KR100666484B1 (ko) * 2005-02-04 2007-01-09 삼성전자주식회사 반도체 메모리 장치의 입출력 회로 및 입출력 방법
WO2010047674A1 (en) 2008-10-20 2010-04-29 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Low molecular weight thyroid stimulating hormone receptor (tshr) agonists
CN101762915B (zh) * 2008-12-24 2013-04-17 北京京东方光电科技有限公司 Tft-lcd阵列基板及其驱动方法
JP5965387B2 (ja) 2010-04-08 2016-08-03 アメリカ合衆国 Ｔｓｈ受容体用のインバースアゴニストおよびニュートラルアンタゴニスト
PL2900675T3 (pl) * 2012-09-28 2019-08-30 Takeda Pharmaceutical Company Limited Sposób wytwarzania pochodnej tienopirymidyny
JP2022551316A (ja) 2019-10-10 2022-12-08 ミオバント サイエンシズ ゲーエムベーハー Ｎ－（４－（１－（２，６－ジフルオロベンジル）－５－（（ジメチルアミノ）メチル）－３－（６－メトキシ－３－ピリダジニル）－２，４－ジオキソ－１，２，３，４－テトラヒドロチエノ［２，３－ｄ］ピリミジン－６－イル）フェニル）－Ｎ’－メトキシ尿素の結晶形

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0303306B1 (de) 1987-08-08 1993-03-10 Akzo N.V. Kontrazeptives Implantat
DE19632423A1 (de) * 1996-08-12 1998-02-19 Merck Patent Gmbh Thienopyrimidine
TW564247B (en) 1999-04-08 2003-12-01 Akzo Nobel Nv Bicyclic heteraromatic compound

Also Published As

Publication number Publication date
CN1551883A (zh) 2004-12-01
AU2002333750B2 (en) 2008-02-21
NZ531375A (en) 2005-06-24
HUP0401443A3 (en) 2008-05-28
DE60207280T2 (de) 2006-05-18
CA2457212C (en) 2011-02-15
US7375109B2 (en) 2008-05-20
RU2004110036A (ru) 2005-10-10
WO2003020727A1 (en) 2003-03-13
IL160194A0 (en) 2004-07-25
PE20030467A1 (es) 2003-05-26
CN1261437C (zh) 2006-06-28
ZA200401459B (en) 2004-11-22
IS2419B (is) 2008-10-15
IS7152A (is) 2004-02-13
DK1427734T3 (da) 2006-03-06
KR20040029135A (ko) 2004-04-03
IL160194A (en) 2009-06-15
ATE309251T1 (de) 2005-11-15
US20040180907A1 (en) 2004-09-16
NO328792B1 (no) 2010-05-18
EP1427734B1 (de) 2005-11-09
RU2294331C2 (ru) 2007-02-27
HUP0401443A2 (hu) 2004-11-29
ECSP044990A (es) 2004-04-28
KR100891630B1 (ko) 2009-04-03
MXPA04002046A (es) 2004-07-16
EP1427734A1 (de) 2004-06-16
ES2252540T3 (es) 2006-05-16
AR036408A1 (es) 2004-09-08
JP2005504784A (ja) 2005-02-17
BR0212173A (pt) 2004-07-20
CY1106052T1 (el) 2011-04-06
PL368388A1 (en) 2005-03-21
JP4263094B2 (ja) 2009-05-13
CA2457212A1 (en) 2003-03-13
NO20040922L (no) 2004-03-03
DE60207280D1 (de) 2005-12-15

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AU2002337035A1 (en) Thieno[2,3-d]pyrimidines with combined LH and FSH agonistic activity
EP1322651B1 (de) Bicyclische heteroaromatische verbindungen
HRP20040194A2 (en) GLYCINE-SUBSTITUTED THIENO [2,3-d] PYRIMIDINES WITH COMBINED LH AND FSH AGONISTIC ACTIVITY
AU2002333750A1 (en) Glycine-substituted thieno[2,3-d]pyrimidines with combined LH and FSH agonistic activity
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