HRP20040200A2 - Process for the preparation of 3-spiro'cyclohexam-1,3'-'3h ^indolin-2'-one^ derivatives - Google Patents

Process for the preparation of 3-spiro'cyclohexam-1,3'-'3h ^indolin-2'-one^ derivatives

Info

Publication number
HRP20040200A2
HRP20040200A2 HR20040200A HRP20040200A HRP20040200A2 HR P20040200 A2 HRP20040200 A2 HR P20040200A2 HR 20040200 A HR20040200 A HR 20040200A HR P20040200 A HRP20040200 A HR P20040200A HR P20040200 A2 HRP20040200 A2 HR P20040200A2
Authority
HR
Croatia
Prior art keywords
formula
compound
preparation
cyclohexam
indolin
Prior art date
Application number
HR20040200A
Other languages
English (en)
Inventor
Csik�s �va
Gonczi Csaba
Hajd� F�lix
Hermecz Istv�n
H�ja Gergely
H�ja Gergelyn�
Majl�th Csilla
Nagy Lajos
S�nt�n� Csutor Andrea
Szomor Tiborn�
Szvoboda Gy�rgyn�
Original Assignee
Sanofi-Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from HU0103122A external-priority patent/HU0103122D0/hu
Priority claimed from HU0202193A external-priority patent/HUP0202193A2/hu
Application filed by Sanofi-Aventis filed Critical Sanofi-Aventis
Publication of HRP20040200A2 publication Critical patent/HRP20040200A2/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/96Spiro-condensed ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
HR20040200A 2001-07-31 2002-07-25 Process for the preparation of 3-spiro'cyclohexam-1,3'-'3h ^indolin-2'-one^ derivatives HRP20040200A2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
HU0103122A HU0103122D0 (en) 2001-07-31 2001-07-31 Chemical process chemical process chemical process
HU0202193A HUP0202193A2 (hu) 2002-07-04 2002-07-04 Eljárás egy spiro[ciklohexán-1,3'-[3'H]indolin]-2'-on-származék előállítására
PCT/HU2002/000075 WO2003011827A1 (en) 2001-07-31 2002-07-25 Process for the preparation of 3-spiro'cyclohexam-1,3'-'3h!indolin-2'-one! derivatives

Publications (1)

Publication Number Publication Date
HRP20040200A2 true HRP20040200A2 (en) 2005-06-30

Family

ID=89980593

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20040200A HRP20040200A2 (en) 2001-07-31 2002-07-25 Process for the preparation of 3-spiro'cyclohexam-1,3'-'3h ^indolin-2'-one^ derivatives

Country Status (15)

Country Link
US (1) US7619082B2 (pl)
EP (1) EP1421064B1 (pl)
JP (1) JP4520145B2 (pl)
CN (1) CN1243736C (pl)
AT (1) ATE295350T1 (pl)
BR (1) BR0211445A (pl)
CA (1) CA2453946C (pl)
DE (1) DE60204154T2 (pl)
DK (1) DK1421064T3 (pl)
ES (1) ES2240781T3 (pl)
HR (1) HRP20040200A2 (pl)
MX (1) MXPA04000949A (pl)
PL (1) PL205571B1 (pl)
PT (1) PT1421064E (pl)
WO (1) WO2003011827A1 (pl)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2740136B1 (fr) 1995-10-24 1998-01-09 Sanofi Sa Derives d'indolin-2-one, procede pour leur preparation et les compositions pharmaceutiques les contenant
HU225150B1 (en) * 1999-07-15 2006-07-28 Sanofi Aventis Novel process for producing 2-methoxy-4-(t-butylaminocarbonyl)-benzenesulfonyl chloride
HUP9902376A3 (en) * 1999-07-15 2002-11-28 Sanofi Aventis Process for producing n-(1,1-dimethyl)-4-[[s'-ethoxi-4-cis-[2-(4-morpholino)-ethoxi]-2'-oxospiro[cyclohexane-1,3'-[3h]indole]-1'(2'h)yl]-sulfonyl]-3-methoxybenzamide and its salts

Also Published As

Publication number Publication date
CN1537099A (zh) 2004-10-13
MXPA04000949A (es) 2004-06-25
EP1421064A1 (en) 2004-05-26
US7619082B2 (en) 2009-11-17
CA2453946A1 (en) 2003-02-13
ATE295350T1 (de) 2005-05-15
BR0211445A (pt) 2004-07-20
CN1243736C (zh) 2006-03-01
CA2453946C (en) 2008-12-09
JP2005501053A (ja) 2005-01-13
DK1421064T3 (da) 2005-08-29
JP4520145B2 (ja) 2010-08-04
DE60204154T2 (de) 2006-01-19
PT1421064E (pt) 2005-08-31
US20040225124A1 (en) 2004-11-11
PL205571B1 (pl) 2010-05-31
ES2240781T3 (es) 2005-10-16
DE60204154D1 (de) 2005-06-16
WO2003011827A1 (en) 2003-02-13
PL367292A1 (pl) 2005-02-21
EP1421064B1 (en) 2005-05-11

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