HRP20040430A2 - Process for reacting alkaloids and use of the reaction products in the preparation of medicaments - Google Patents

Process for reacting alkaloids and use of the reaction products in the preparation of medicaments Download PDF

Info

Publication number: HRP20040430A2
Authority: HR; Croatia
Prior art keywords: alkaloid; reaction; reaction product; alkaloids; water
Prior art date: 2001-11-15

Application number

HR20040430A

Other languages

English (en)

Croatian (hr)

Inventor

Wassyl Nowicky

Original Assignee

Nowicky Wassili

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-11-15

Filing date

2002-10-28

Publication date

2004-08-31

2002-10-28 Application filed by Nowicky Wassili filed Critical Nowicky Wassili

2004-08-31 Publication of HRP20040430A2 publication Critical patent/HRP20040430A2/hr

2012-11-30 Publication of HRP20040430B1 publication Critical patent/HRP20040430B1/xx

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07G—COMPOUNDS OF UNKNOWN CONSTITUTION
- C07G5/00—Alkaloids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/564—Three-membered rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/59—Hydrogenated pyridine rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
- C07F9/6509—Six-membered rings
- C07F9/650952—Six-membered rings having the nitrogen atoms in the positions 1 and 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6527—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and oxygen atoms as the only ring hetero atoms
- C07F9/6533—Six-membered rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6536—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and sulfur atoms with or without oxygen atoms, as the only ring hetero atoms
- C07F9/6539—Five-membered rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6581—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms
- C07F9/6584—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms having one phosphorus atom as ring hetero atom
- C07F9/65842—Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring
- C07F9/65846—Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring the phosphorus atom being part of a six-membered ring which may be condensed with another ring system

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Pharmacology & Pharmacy (AREA)
Biochemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Diabetes (AREA)
Physical Education & Sports Medicine (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Rheumatology (AREA)
Biomedical Technology (AREA)
Pain & Pain Management (AREA)
Orthopedic Medicine & Surgery (AREA)
Epidemiology (AREA)
Immunology (AREA)
Obesity (AREA)
Hematology (AREA)
Communicable Diseases (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Oncology (AREA)
Virology (AREA)
Dermatology (AREA)
Psychiatry (AREA)
Pulmonology (AREA)
Hospice & Palliative Care (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

HR20040430A 2001-11-15 2002-10-28 Process for reacting alkaloids and use of the reaction products in the preparation of medicaments HRP20040430A2 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
CH02094/01A CH695417A5 (de)	2001-11-15	2001-11-15	Verfahren zur Umsetzung von Alkaloiden.
PCT/EP2002/012003 WO2003041721A1 (en)	2001-11-15	2002-10-28	Process for reacting alkaloids and use of the reaction products in the preparation of medicaments

Publications (2)

Publication Number	Publication Date
HRP20040430A2 true HRP20040430A2 (en)	2004-08-31
HRP20040430B1 HRP20040430B1 (pl)	2012-11-30

Family

ID=4567486

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HR20040430A HRP20040430A2 (en)	2001-11-15	2002-10-28	Process for reacting alkaloids and use of the reaction products in the preparation of medicaments

Country Status (38)

Country	Link
US (1)	US20050043340A1 (pl)
EP (1)	EP1443943B1 (pl)
JP (1)	JP2005509006A (pl)
KR (1)	KR100849488B1 (pl)
CN (1)	CN100436462C (pl)
AR (1)	AR037527A1 (pl)
AT (1)	ATE485826T1 (pl)
AU (1)	AU2002346888B2 (pl)
BR (1)	BR0214173A (pl)
CA (1)	CA2465723C (pl)
CH (1)	CH695417A5 (pl)
CO (1)	CO5580784A2 (pl)
CR (1)	CR7340A (pl)
CU (1)	CU23451B7 (pl)
CY (1)	CY1111139T1 (pl)
DE (1)	DE60238134D1 (pl)
DK (1)	DK1443943T3 (pl)
EA (1)	EA007097B1 (pl)
EC (1)	ECSP045107A (pl)
ES (1)	ES2353207T3 (pl)
GE (1)	GEP20053701B (pl)
HR (1)	HRP20040430A2 (pl)
HU (1)	HU229688B1 (pl)
IL (2)	IL161766A0 (pl)
IS (1)	IS2812B (pl)
MA (1)	MA26232A1 (pl)
MX (1)	MXPA04004643A (pl)
NO (1)	NO334701B1 (pl)
NZ (1)	NZ532941A (pl)
PL (1)	PL212111B1 (pl)
PT (1)	PT1443943E (pl)
RS (1)	RS51219B (pl)
SA (1)	SA02230496B1 (pl)
TN (1)	TNSN04084A1 (pl)
TW (1)	TWI262080B (pl)
UA (1)	UA76535C2 (pl)
WO (1)	WO2003041721A1 (pl)
ZA (1)	ZA200403371B (pl)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1459753A1 (en)	2003-03-18	2004-09-22	Nowicky, Wassyl, Dipl.-Ing. DDr.	Quaternary chelidonine and alkaloid derivatives, process for their preparation and their use in the manufacture of medicaments
WO2006053680A1 (en) *	2004-11-19	2006-05-26	Nowicky Wassili	Ex vivo cancer diagnostic method
WO2006053649A1 (en) *	2004-11-19	2006-05-26	Nowicky Wassili	Method for the detection of cancer
WO2007073919A2 (en)	2005-12-28	2007-07-05	Nowicky Wassili	Method and kit for the detection of cancer
ITMI20080284A1 (it) *	2008-02-22	2009-08-23	Indena Spa	Agenti antitumorali a struttura benzofenantridinica e formulazioni che li contengono
CA2941315C (en) *	2016-08-12	2018-03-06	Api Labs Inc.	High thebaine poppy and methods of producing the same

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3865830A (en) *	1969-06-16	1975-02-11	Nikolai Mikhailovich Turkevich	Thiophosphamide derivatives of isoquinoline alkaloids, method of producing and application thereof
SU368254A1 (ru)	1969-06-16	1973-01-26	А. И. Потопальский , В. М. Новицкий Львовский государственный медицинский институт	Способ получения соединений тиофосфамида с алкалоидами чистотела большого
AT354644B (de) *	1975-12-19	1980-01-25	Nowicky Wassili	Verfahren zur herstellung von neuen salzen von alkaloidderivaten von thiophosphorsaeure
AT377988B (de) *	1976-06-28	1985-05-28	Nowicky Wassili	Verfahren zur herstellung von neuen phosphorderivaten von alkaloiden
DE3128018A1 (de)	1981-07-13	1983-04-07	Wassyl 1060 Wien Nowicky	"verfahren zum diagnostizieren und fuer die therapeutische behandlung von tumoren und/oder infektioesen krankheiten verschiedenster art unter praeparativem einsatz von alkaloid-verbindungen bzw. deren salze"
US4970212A (en) *	1982-05-18	1990-11-13	Nowicky Wassili	Method of treating human illnesses which compromise the ability to mount an effective immunological response
AT407608B (de) *	1994-03-18	2001-05-25	Nowicky Wassili	Mittel zur behandlung von osteoporose
AT407833B (de) *	1995-06-01	2001-06-25	Nowicky Wassyl Dr	Mittel zur behandlung von strahlenschäden
AT408719B (de) *	2000-03-22	2002-02-25	Nowicky Wassili	Mittel zur behandlung von hepatitis c

2001
- 2001-11-15 CH CH02094/01A patent/CH695417A5/de not_active IP Right Cessation
2002
- 2002-10-25 TW TW091125317A patent/TWI262080B/zh not_active IP Right Cessation
- 2002-10-28 DE DE60238134T patent/DE60238134D1/de not_active Expired - Lifetime
- 2002-10-28 KR KR1020047007480A patent/KR100849488B1/ko not_active Expired - Fee Related
- 2002-10-28 EA EA200400679A patent/EA007097B1/ru not_active IP Right Cessation
- 2002-10-28 ES ES02783017T patent/ES2353207T3/es not_active Expired - Lifetime
- 2002-10-28 PT PT02783017T patent/PT1443943E/pt unknown
- 2002-10-28 GE GE8206A patent/GEP20053701B/en unknown
- 2002-10-28 HU HU0402365A patent/HU229688B1/hu unknown
- 2002-10-28 NZ NZ532941A patent/NZ532941A/en not_active IP Right Cessation
- 2002-10-28 AT AT02783017T patent/ATE485826T1/de active
- 2002-10-28 JP JP2003543608A patent/JP2005509006A/ja active Pending
- 2002-10-28 BR BR0214173-6A patent/BR0214173A/pt not_active IP Right Cessation
- 2002-10-28 US US10/495,729 patent/US20050043340A1/en not_active Abandoned
- 2002-10-28 RS YUP-408/04A patent/RS51219B/sr unknown
- 2002-10-28 WO PCT/EP2002/012003 patent/WO2003041721A1/en not_active Ceased
- 2002-10-28 HR HR20040430A patent/HRP20040430A2/hr not_active IP Right Cessation
- 2002-10-28 MX MXPA04004643A patent/MXPA04004643A/es active IP Right Grant
- 2002-10-28 UA UA20040604558A patent/UA76535C2/uk unknown
- 2002-10-28 PL PL368879A patent/PL212111B1/pl unknown
- 2002-10-28 EP EP02783017A patent/EP1443943B1/en not_active Expired - Lifetime
- 2002-10-28 DK DK02783017.3T patent/DK1443943T3/da active
- 2002-10-28 IL IL16176602A patent/IL161766A0/xx unknown
- 2002-10-28 AU AU2002346888A patent/AU2002346888B2/en not_active Ceased
- 2002-10-28 CA CA002465723A patent/CA2465723C/en not_active Expired - Fee Related
- 2002-11-15 CN CNB021513384A patent/CN100436462C/zh not_active Expired - Fee Related
- 2002-11-15 AR ARP020104397A patent/AR037527A1/es unknown
- 2002-12-30 SA SA02230496A patent/SA02230496B1/ar unknown
2004
- 2004-04-30 IS IS7245A patent/IS2812B/is unknown
- 2004-05-04 ZA ZA200403371A patent/ZA200403371B/en unknown
- 2004-05-04 IL IL161766A patent/IL161766A/en not_active IP Right Cessation
- 2004-05-05 NO NO20041845A patent/NO334701B1/no not_active IP Right Cessation
- 2004-05-11 CR CR7340A patent/CR7340A/es unknown
- 2004-05-13 TN TNP2004000084A patent/TNSN04084A1/en unknown
- 2004-05-14 EC EC2004005107A patent/ECSP045107A/es unknown
- 2004-05-14 MA MA27679A patent/MA26232A1/fr unknown
- 2004-05-17 CU CU20040105A patent/CU23451B7/es not_active IP Right Cessation
- 2004-06-01 CO CO04051024A patent/CO5580784A2/es not_active Application Discontinuation
2011
- 2011-01-24 CY CY20111100077T patent/CY1111139T1/el unknown

Also Published As

Publication number	Publication date
MA26232A1 (fr)	2004-07-01
CO5580784A2 (es)	2005-11-30
ECSP045107A (es)	2004-06-28
MXPA04004643A (es)	2005-03-14
CR7340A (es)	2004-12-06
NO20041845D0 (no)	2004-05-05
WO2003041721A1 (en)	2003-05-22
HUP0402365A2 (hu)	2005-02-28
KR100849488B1 (ko)	2008-07-31
UA76535C2 (en)	2006-08-15
ATE485826T1 (de)	2010-11-15
SA02230496B1 (ar)	2008-09-10
JP2005509006A (ja)	2005-04-07
RS40804A (sr)	2006-12-15
DK1443943T3 (da)	2011-02-14
EP1443943A1 (en)	2004-08-11
IL161766A (en)	2009-11-18
US20050043340A1 (en)	2005-02-24
AU2002346888B2 (en)	2007-03-22
CU23451B7 (es)	2009-10-16
TWI262080B (en)	2006-09-21
RS51219B (sr)	2010-12-31
NO20041845L (no)	2004-06-25
EP1443943B1 (en)	2010-10-27
NO334701B1 (no)	2014-05-12
HRP20040430B1 (pl)	2012-11-30
PL368879A1 (pl)	2005-04-04
ZA200403371B (en)	2005-05-04
CY1111139T1 (el)	2015-06-11
CA2465723C (en)	2010-01-05
TNSN04084A1 (en)	2006-06-01
IS7245A (is)	2004-04-30
HK1054041A1 (zh)	2003-11-14
IL161766A0 (en)	2005-11-20
AR037527A1 (es)	2004-11-17
CN100436462C (zh)	2008-11-26
DE60238134D1 (de)	2010-12-09
PL212111B1 (pl)	2012-08-31
PT1443943E (pt)	2010-12-03
HU229688B1 (en)	2014-04-28
KR20050040859A (ko)	2005-05-03
GEP20053701B (en)	2005-12-12
BR0214173A (pt)	2004-09-28
AU2002346888C1 (en)	2003-05-26
EA007097B1 (ru)	2006-06-30
IS2812B (is)	2012-11-15
ES2353207T3 (es)	2011-02-28
NZ532941A (en)	2006-08-31
CA2465723A1 (en)	2003-05-22
CH695417A5 (de)	2006-05-15
CN1422859A (zh)	2003-06-11
EA200400679A1 (ru)	2004-10-28

Legal Events

Date	Code	Title	Description
2004-08-24	ARAI	Request for the grant of a patent on the basis of the submitted results of a substantive examination of a patent application
2004-08-31	A1OB	Publication of a patent application
2012-11-30	B1PR	Patent granted
2013-09-19	ODRP	Renewal fee for the maintenance of a patent	Payment date: 20130919 Year of fee payment: 12
2015-05-13	PBON	Lapse due to non-payment of renewal fee	Effective date: 20141028

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