HRP20040565A2 - Crystalline venlafaxine base and novel polymorphsof venlafaxine hidrochloride, processes for preparing thereof - Google Patents

Crystalline venlafaxine base and novel polymorphsof venlafaxine hidrochloride, processes for preparing thereof

Info

Publication number
HRP20040565A2
HRP20040565A2 HR20040565A HRP20040565A HRP20040565A2 HR P20040565 A2 HRP20040565 A2 HR P20040565A2 HR 20040565 A HR20040565 A HR 20040565A HR P20040565 A HRP20040565 A HR P20040565A HR P20040565 A2 HRP20040565 A2 HR P20040565A2
Authority
HR
Croatia
Prior art keywords
venlafaxine
polymorphsof
hidrochloride
preparing
novel
Prior art date
Application number
HR20040565A
Other languages
English (en)
Inventor
Aronhime Judith
A. Nisnevich Gennady
Dolitzky Ben-Zion
Wizel Shlomit
Original Assignee
Teva Pharmaceutical Industries Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Pharmaceutical Industries Ltd. filed Critical Teva Pharmaceutical Industries Ltd.
Publication of HRP20040565A2 publication Critical patent/HRP20040565A2/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/74—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/64—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by singly-bound oxygen atoms
    • C07C217/66—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by singly-bound oxygen atoms with singly-bound oxygen atoms and six-membered aromatic rings bound to the same carbon atom of the carbon chain
    • C07C217/70—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by singly-bound oxygen atoms with singly-bound oxygen atoms and six-membered aromatic rings bound to the same carbon atom of the carbon chain linked by carbon chains having two carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/10—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HR20040565A 2001-11-30 2002-11-20 Crystalline venlafaxine base and novel polymorphsof venlafaxine hidrochloride, processes for preparing thereof HRP20040565A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/000,428 US20020183553A1 (en) 2000-10-19 2001-11-30 Crystalline venlafaxine base and novel polymorphs of venlafaxine hydrochloride, processes for preparing thereof
PCT/US2002/037268 WO2003048082A2 (en) 2001-11-30 2002-11-20 Crystalline venlafaxine base and novel polymorphs of venlafaxine hydrochloride, processes for preparing thereof

Publications (1)

Publication Number Publication Date
HRP20040565A2 true HRP20040565A2 (en) 2005-08-31

Family

ID=21691493

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20040565A HRP20040565A2 (en) 2001-11-30 2002-11-20 Crystalline venlafaxine base and novel polymorphsof venlafaxine hidrochloride, processes for preparing thereof

Country Status (16)

Country Link
US (4) US20020183553A1 (is)
EP (1) EP1474379A4 (is)
JP (1) JP2005511668A (is)
KR (1) KR20040068163A (is)
CN (2) CN1617848A (is)
AU (1) AU2002365874A1 (is)
CA (1) CA2468728A1 (is)
HR (1) HRP20040565A2 (is)
HU (1) HUP0700037A2 (is)
IL (1) IL162171A0 (is)
IS (1) IS7289A (is)
MX (1) MXPA04005193A (is)
NO (1) NO20042732L (is)
PL (1) PL374273A1 (is)
WO (1) WO2003048082A2 (is)
ZA (1) ZA200404080B (is)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE01988460T1 (de) * 2000-10-19 2004-04-22 Teva Pharmaceutical Industries Ltd. Kristalline venlafaxinbase und neue venlafaxin-hydrochlorid-modifikationen sowie verfahren zu deren herstellung
AU1234002A (en) * 2000-10-31 2002-05-15 Ciba Sc Holding Ag Crystalline forms of venlafaxine hydrochloride
AU2002348266A1 (en) * 2001-12-05 2003-06-23 Wyeth Novel crystalline polymorph of venlafaxine hydrochloride and methods for the preparation thereof
UA77234C2 (en) * 2001-12-05 2006-11-15 Wyeth Corp Monohydrate of venlafaxine hydrochloride and methods for its preparation (variants)
US20030191347A1 (en) * 2002-03-28 2003-10-09 Rolf Keltjens Venlafaxine base
DE10359154A1 (de) * 2003-12-16 2005-07-28 Krka Tovarna Zdravil, D.D. Verfahren zur Herstellung von Venlafaxin und Venlafaxinhydrochlorid der Form I
CA2625832A1 (en) * 2005-10-19 2007-04-26 Vinod Kumar Kansal Process for the preparation of highly pure 1-[2-dimethylamino-(4-methoxyphenyl) ethyl]cyclohexanol hydrochloride
PT1954669E (pt) * 2005-12-01 2015-10-23 Auspex Pharmaceuticals Inc Feniletilaminas substituídas com actividade serotoninérgica e/ou norepinefrinérgica
ES2693948T3 (es) * 2007-03-15 2018-12-14 Auspex Pharmaceuticals, Inc. Fenetilamina sustituida con actividad serotoninérgica y/o norepinefrinérgica
CN101279926A (zh) * 2008-05-22 2008-10-08 杭州盛美医药科技开发有限公司 盐酸文拉法辛晶型FormⅠ的制备方法
CA2883641C (en) 2012-09-18 2021-09-14 Auspex Pharmaceuticals, Inc. Formulations pharmacokinetics of deuterated benzoquinoline inhibitors of vesicular monoamine transporter 2
EP3578546A1 (en) 2013-11-15 2019-12-11 Akebia Therapeutics Inc. Solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino}acetic acid, compositions, and uses thereof
CN114767672A (zh) 2015-03-06 2022-07-22 奥斯拜客斯制药有限公司 氘代丁苯那嗪或包含氘代丁苯那嗪的组合物

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL63968A (en) * 1980-10-01 1985-10-31 Glaxo Group Ltd Form 2 ranitidine hydrochloride,its preparation and pharmaceutical compositions containing it
US4535186A (en) * 1983-04-19 1985-08-13 American Home Products Corporation 2-Phenyl-2-(1-hydroxycycloalkyl or 1-hydroxycycloalk-2-enyl)ethylamine derivatives
US4611078A (en) * 1983-10-26 1986-09-09 American Home Products Corporation Substituted phenylacetonitriles
US6197828B1 (en) * 1998-12-01 2001-03-06 Sepracor, Inc. Derivatives of (+)-venlafaxine and methods of preparing and using the same
DE01988460T1 (de) * 2000-10-19 2004-04-22 Teva Pharmaceutical Industries Ltd. Kristalline venlafaxinbase und neue venlafaxin-hydrochlorid-modifikationen sowie verfahren zu deren herstellung
AU1234002A (en) 2000-10-31 2002-05-15 Ciba Sc Holding Ag Crystalline forms of venlafaxine hydrochloride
AU2001235970A1 (en) 2000-12-07 2002-06-18 Dr. Reddy's Research Foundation Novel crystalline polymorphic forms of venlafaxine hydrochloride and a process for their preparation
EP1249447B1 (en) * 2001-04-10 2008-10-22 Alembic Limited Intermediate for the production of 1-[2-dimethylamino-1-(4-methoxyphenyl)-ethyl]-cyclohexanol
AU2002348266A1 (en) * 2001-12-05 2003-06-23 Wyeth Novel crystalline polymorph of venlafaxine hydrochloride and methods for the preparation thereof
AU2002247945A1 (en) * 2001-12-13 2003-06-23 Cadila Healthcare Limited Manufacture of venlafaxine hydrochloride and crystalline polymorphs thereof

Also Published As

Publication number Publication date
CA2468728A1 (en) 2003-06-12
AU2002365874A1 (en) 2003-06-17
WO2003048082A3 (en) 2004-08-26
US20050049304A1 (en) 2005-03-03
EP1474379A2 (en) 2004-11-10
NO20042732L (no) 2004-06-29
MXPA04005193A (es) 2005-02-22
KR20040068163A (ko) 2004-07-30
IL162171A0 (en) 2005-11-20
PL374273A1 (en) 2005-10-03
CN101219962A (zh) 2008-07-16
CN1617848A (zh) 2005-05-18
EP1474379A4 (en) 2006-06-07
US20020183553A1 (en) 2002-12-05
JP2005511668A (ja) 2005-04-28
US6924393B2 (en) 2005-08-02
WO2003048082A2 (en) 2003-06-12
US20040220278A1 (en) 2004-11-04
US20080167498A1 (en) 2008-07-10
IS7289A (is) 2004-05-27
HUP0700037A2 (en) 2007-05-02
ZA200404080B (en) 2007-12-27

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