HRP20040596A2 - Compressed oral pharmaceutical dosage form, with an enteric coating, which contains an acid-labile benzimidazole compound - Google Patents

Compressed oral pharmaceutical dosage form, with an enteric coating, which contains an acid-labile benzimidazole compound Download PDF

Info

Publication number
HRP20040596A2
HRP20040596A2 HR20040596A HRP20040596A HRP20040596A2 HR P20040596 A2 HRP20040596 A2 HR P20040596A2 HR 20040596 A HR20040596 A HR 20040596A HR P20040596 A HRP20040596 A HR P20040596A HR P20040596 A2 HRP20040596 A2 HR P20040596A2
Authority
HR
Croatia
Prior art keywords
acid
benzimidazole compound
pharmaceutically acceptable
excipients
alkaline
Prior art date
Application number
HR20040596A
Other languages
English (en)
Croatian (hr)
Inventor
Javier Lizcano Garcia
Jaume Sangra Perez
Pere Joan Solanas Ibarra
Antonio Lopez Cabrera
Original Assignee
Esteve Labor Dr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Esteve Labor Dr filed Critical Esteve Labor Dr
Publication of HRP20040596A2 publication Critical patent/HRP20040596A2/hr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
HR20040596A 2001-12-18 2002-11-18 Compressed oral pharmaceutical dosage form, with an enteric coating, which contains an acid-labile benzimidazole compound HRP20040596A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES200102820A ES2198195B1 (es) 2001-12-18 2001-12-18 Forma de dosificacion farmaceutica oral comprimida, con recubrimiento enterico, que contiene un compuesto de bencimidazol labil en medio acido.
PCT/ES2002/000536 WO2003051342A1 (es) 2001-12-18 2002-11-18 Forma de dosificacion farmaceutica oral comprimida, con recubrimiento enterico, que contiene un compuesto de bencimidazol labil en medio acido

Publications (1)

Publication Number Publication Date
HRP20040596A2 true HRP20040596A2 (en) 2004-10-31

Family

ID=8499777

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20040596A HRP20040596A2 (en) 2001-12-18 2002-11-18 Compressed oral pharmaceutical dosage form, with an enteric coating, which contains an acid-labile benzimidazole compound

Country Status (19)

Country Link
US (1) US7217429B2 (de)
EP (1) EP1464331B9 (de)
JP (1) JP4523278B2 (de)
KR (1) KR100877649B1 (de)
AT (1) ATE410149T1 (de)
AU (1) AU2002350750B2 (de)
CA (1) CA2470609C (de)
DE (1) DE60229295D1 (de)
DK (1) DK1464331T3 (de)
ES (2) ES2198195B1 (de)
HR (1) HRP20040596A2 (de)
HU (1) HUP0402488A3 (de)
IL (2) IL162544A0 (de)
MX (1) MXPA04005902A (de)
NO (1) NO20042630L (de)
NZ (1) NZ533886A (de)
PT (1) PT1464331E (de)
WO (1) WO2003051342A1 (de)
ZA (1) ZA200405078B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI372066B (en) * 2003-10-01 2012-09-11 Wyeth Corp Pantoprazole multiparticulate formulations
ES2278511B1 (es) * 2005-07-28 2008-06-16 Laboratorios Almirall S.A. Comprimidos con perfil de disolucion mejorado.
WO2007100984A2 (en) * 2006-02-24 2007-09-07 Allergan, Inc. Beads containing pyridin-sulfinyl benzoimidazole sulfonyl phenoxy acetate derivatives
US8252330B2 (en) * 2009-01-05 2012-08-28 Mcneil-Ppc, Inc. Tablet containing coated particles of cetirizine, pseudoephedrine, and/or naproxen
CA2748728C (en) * 2009-01-05 2017-01-03 Mcneil-Ppc, Inc. Tablet containing cetirizine, pseudoephedrine, and naproxen containing a barrier layer
US8246988B2 (en) * 2009-01-05 2012-08-21 Mcneil-Ppc, Inc. Three layer tablet containing cetirizine, pseudoephedrine, and naproxen
WO2010117756A2 (en) * 2009-03-31 2010-10-14 Dr. Reddy's Laboratories Ltd Substituted benzimidazole pharmaceutical formulations
EP2345408A3 (de) * 2010-01-08 2012-02-29 Dr. Reddy's Laboratories Ltd. Säurelabile Arzneimittelformulierungen
US20130122090A1 (en) * 2010-07-22 2013-05-16 Lupin Limited Multiple Unit Tablet Composition
US10058542B1 (en) 2014-09-12 2018-08-28 Thioredoxin Systems Ab Composition comprising selenazol or thiazolone derivatives and silver and method of treatment therewith
US20170042806A1 (en) 2015-04-29 2017-02-16 Dexcel Pharma Technologies Ltd. Orally disintegrating compositions
WO2017145146A1 (en) 2016-02-25 2017-08-31 Dexcel Pharma Technologies Ltd. Compositions comprising proton pump inhibitors
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2189699A (en) 1986-04-30 1987-11-04 Haessle Ab Coated acid-labile medicaments
GB2189698A (en) * 1986-04-30 1987-11-04 Haessle Ab Coated omeprazole tablets
DK0723436T3 (da) * 1994-07-08 2001-11-26 Astrazeneca Ab Tabletteret flerenhedsdoseringsform
SE9402431D0 (sv) * 1994-07-08 1994-07-08 Astra Ab New tablet formulation
ES2094694B1 (es) 1995-02-01 1997-12-16 Esteve Quimica Sa Nueva formulacion farmaceuticamente estable de un compuesto de bencimidazol y su proceso de obtencion.
SE9500422D0 (sv) * 1995-02-06 1995-02-06 Astra Ab New oral pharmaceutical dosage forms
ATE286394T1 (de) * 1995-09-21 2005-01-15 Pharma Pass Ii Llc Ein säurelabile omeprazol enthaltende arzneizusammensetzung und verfahren zu deren herstellung
SE9600070D0 (sv) * 1996-01-08 1996-01-08 Astra Ab New oral pharmaceutical dosage forms
SE9700885D0 (sv) * 1997-03-12 1997-03-12 Astra Ab New pharmaceutical formulation
ES2168043B1 (es) * 1999-09-13 2003-04-01 Esteve Labor Dr Forma farmaceutica solida oral de liberacion modificada que contiene un compuesto de bencimidazol labil en medio acido.
JP2002363080A (ja) * 2001-06-08 2002-12-18 Towa Yakuhin Kk 安定な内服用抗潰瘍製剤の製造法

Also Published As

Publication number Publication date
HUP0402488A3 (en) 2009-09-28
US7217429B2 (en) 2007-05-15
ES2198195A1 (es) 2004-01-16
ATE410149T1 (de) 2008-10-15
ES2198195B1 (es) 2004-10-01
NO20042630L (no) 2004-08-13
IL162544A (en) 2010-04-29
NZ533886A (en) 2005-12-23
IL162544A0 (en) 2005-11-20
JP2005523884A (ja) 2005-08-11
MXPA04005902A (es) 2004-09-13
EP1464331B9 (de) 2009-10-14
KR20040079906A (ko) 2004-09-16
DK1464331T3 (da) 2009-01-05
JP4523278B2 (ja) 2010-08-11
KR100877649B1 (ko) 2009-01-12
CA2470609A1 (en) 2003-06-26
WO2003051342A1 (es) 2003-06-26
HUP0402488A2 (hu) 2005-05-30
DE60229295D1 (de) 2008-11-20
AU2002350750A1 (en) 2003-06-30
AU2002350750B2 (en) 2008-10-16
EP1464331A1 (de) 2004-10-06
CA2470609C (en) 2010-09-28
PT1464331E (pt) 2008-11-19
ZA200405078B (en) 2005-06-27
ES2315416T3 (es) 2009-04-01
US20030118650A1 (en) 2003-06-26
EP1464331B1 (de) 2008-10-08

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Payment date: 20111110

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