HRP20040802A2 - Sulfonyl-derivatives as novel inhibitors of histon - Google Patents

Sulfonyl-derivatives as novel inhibitors of histon

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Publication number
HRP20040802A2
HRP20040802A2 HR20040802A HRP20040802A HRP20040802A2 HR P20040802 A2 HRP20040802 A2 HR P20040802A2 HR 20040802 A HR20040802 A HR 20040802A HR P20040802 A HRP20040802 A HR P20040802A HR P20040802 A2 HRP20040802 A2 HR P20040802A2
Authority
HR
Croatia
Prior art keywords
6alkyl
4alkyl
aminoc1
hydroxyc1
amino
Prior art date
Application number
HR20040802A
Other languages
English (en)
Croatian (hr)
Inventor
Van Emelen Kristof
Arts Janine
Leo
Hans
Sven
Marc
Meerpoel Lieven
Isabelle
Virginie
Alexey
Original Assignee
Janssen Pharmaceutica N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica N.V. filed Critical Janssen Pharmaceutica N.V.
Publication of HRP20040802A2 publication Critical patent/HRP20040802A2/hr

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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/402—1-aryl substituted, e.g. piretanide
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