HRP20041136A2 - Novel crystal forms of ondansetron, processes fortheir preparation, pharmaceutical compositions containing the novel forms and methods for treating nausea using them - Google Patents

Novel crystal forms of ondansetron, processes fortheir preparation, pharmaceutical compositions containing the novel forms and methods for treating nausea using them Download PDF

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Publication number
HRP20041136A2
HRP20041136A2 HR20041136A HRP20041136A HRP20041136A2 HR P20041136 A2 HRP20041136 A2 HR P20041136A2 HR 20041136 A HR20041136 A HR 20041136A HR P20041136 A HRP20041136 A HR P20041136A HR P20041136 A2 HRP20041136 A2 HR P20041136A2
Authority
HR
Croatia
Prior art keywords
ondansetron
crystalline form
solution
degrees
methanol
Prior art date
Application number
HR20041136A
Other languages
English (en)
Croatian (hr)
Inventor
Szabo Csaba
Molnar Szandor
Meszaros Sos Erzsebet
Salvi Szabolcs
Tamas Tivadar
Aronhime Judith
Original Assignee
Teva Gy�gyszergy�r R�szv�nyt�rsas�g
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Gy�gyszergy�r R�szv�nyt�rsas�g filed Critical Teva Gy�gyszergy�r R�szv�nyt�rsas�g
Publication of HRP20041136A2 publication Critical patent/HRP20041136A2/hr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HR20041136A 2002-04-30 2003-04-29 Novel crystal forms of ondansetron, processes fortheir preparation, pharmaceutical compositions containing the novel forms and methods for treating nausea using them HRP20041136A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37639502P 2002-04-30 2002-04-30
PCT/US2003/013220 WO2003093260A1 (en) 2002-04-30 2003-04-29 Novel crystal forms of ondansetron, processes for their preparation, pharmaceutical compositions containing the novel forms and methods for treating nausea using them

Publications (1)

Publication Number Publication Date
HRP20041136A2 true HRP20041136A2 (en) 2005-04-30

Family

ID=29401340

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20041136A HRP20041136A2 (en) 2002-04-30 2003-04-29 Novel crystal forms of ondansetron, processes fortheir preparation, pharmaceutical compositions containing the novel forms and methods for treating nausea using them

Country Status (15)

Country Link
US (1) US20040019093A1 (pl)
EP (1) EP1465887A1 (pl)
JP (1) JP2005529908A (pl)
KR (1) KR20040104677A (pl)
CN (1) CN1665803A (pl)
AU (1) AU2003223763A1 (pl)
CA (1) CA2483532A1 (pl)
DE (1) DE20320528U1 (pl)
HR (1) HRP20041136A2 (pl)
IL (1) IL164905A0 (pl)
MX (1) MXPA04010845A (pl)
NO (1) NO20045233L (pl)
PL (1) PL373192A1 (pl)
WO (1) WO2003093260A1 (pl)
ZA (1) ZA200408935B (pl)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK6182003A3 (en) * 2000-10-30 2004-03-02 Teva Pharma Crystalline and solvated forms of ondansetrone hydrochloride and preparation thereof
ATE364611T1 (de) * 2002-04-29 2007-07-15 Teva Gyogyszergyar Zartkoeruee Verfahren zur herstellung von 1,2,3,9-tetrahydro- 9-methyl-3- (2-methyl-1h-imidazol-1-yl)methylö- h-carbazol-4-on
FI6164U1 (fi) * 2003-01-09 2004-03-15 Synthon Bv Ondansetronmuotoja
ES2238001B1 (es) * 2004-01-21 2006-11-01 Vita Cientifica, S.L. Nuevas formas polimorficas de ondansetron, procedimientos para su preparacion, composiciones farmaceuticas que los contienen y su uso como aantiemeticos.
US7288660B2 (en) * 2004-05-07 2007-10-30 Taro Pharmaceutical Industries Limited Process for preparing ondansetron hydrochloride dihydrate having a defined particle size
TW200800954A (en) * 2006-03-16 2008-01-01 Astrazeneca Ab Novel crystal modifications
HUE038022T4 (hu) 2006-10-02 2023-02-28 Spepharm Ag Nem mukoadhezív filmdózisformák
CN103025321A (zh) 2010-03-23 2013-04-03 生物联合制药公司 快速溶解的药物释放系统
EP2377526A1 (en) 2010-03-23 2011-10-19 BioAlliance Pharma Fast dissolving drug delivery systems
TWI665190B (zh) 2013-11-15 2019-07-11 阿克比治療有限公司 ｛［５－（３－氯苯基）－３－羥基吡啶－２－羰基］胺基｝乙酸之固體型式，其組合物及用途

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8518745D0 (en) * 1985-07-24 1985-08-29 Glaxo Group Ltd Heterocyclic compounds
HU196598B (en) * 1986-04-25 1988-12-28 Richter Gedeon Vegyeszet Process for producing 1- and/or 8-substituted 2-halogenated ergoline derivatives and pharmaceutics comprising such compounds
GB8630071D0 (en) * 1986-12-17 1987-01-28 Glaxo Group Ltd Medicaments
US5344658A (en) * 1989-06-28 1994-09-06 Glaxo Group Limited Process and composition using ondansetron
WO1993000074A1 (en) * 1991-06-26 1993-01-07 Sepracor, Inc. Method and compositions for treating emesis, nausea and other disorders using optically pure r(+) ondansetron
CA2106642C (en) * 1992-10-14 2005-08-16 Peter Bod Carbazolone derivatives and process for preparing the same
GB2291005B (en) * 1994-07-08 1998-05-20 Milwaukee Electric Tool Corp Bevel angle adjustment mechanism for a compound mitre saw
GB9423588D0 (en) * 1994-11-22 1995-01-11 Glaxo Wellcome Inc Compositions
GB9423511D0 (en) * 1994-11-22 1995-01-11 Glaxo Wellcome Inc Compositions
JP3533519B2 (ja) * 2000-03-09 2004-05-31 株式会社アドバンスト・ディスプレイ Ｔｆｔ基板、フィルムキャリアおよび液晶表示素子の製法
US20020115707A1 (en) * 2001-01-11 2002-08-22 Rami Lidor-Hadas Process for preparing pure ondansetron hydrochloride dihydrate
ATE364611T1 (de) * 2002-04-29 2007-07-15 Teva Gyogyszergyar Zartkoeruee Verfahren zur herstellung von 1,2,3,9-tetrahydro- 9-methyl-3- (2-methyl-1h-imidazol-1-yl)methylö- h-carbazol-4-on

Also Published As

Publication number Publication date
IL164905A0 (en) 2005-12-18
EP1465887A1 (en) 2004-10-13
US20040019093A1 (en) 2004-01-29
PL373192A1 (pl) 2005-08-22
JP2005529908A (ja) 2005-10-06
ZA200408935B (en) 2006-07-26
CA2483532A1 (en) 2003-11-13
AU2003223763A1 (en) 2003-11-17
CN1665803A (zh) 2005-09-07
DE20320528U1 (de) 2004-09-16
KR20040104677A (ko) 2004-12-10
MXPA04010845A (es) 2005-01-25
WO2003093260A1 (en) 2003-11-13
NO20045233L (no) 2005-01-28

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Legal Events

Date Code Title Description
A1OB Publication of a patent application
AIPI Request for the grant of a patent on the basis of a substantive examination of a patent application
PNAN Change of the applicant name, address/residence

Owner name: TEVA GYOGYSZERGYAR ZARTKOERUEN MUKOEDO RESZVENYTAR

ODRP Renewal fee for the maintenance of a patent

Payment date: 20070410

Year of fee payment: 5

OBST Application withdrawn