HRP20041231A2 - Acyloxypyrrolidine derivatives and use thereof as ligands of v1b or both v1b and v1a receptors - Google Patents

Acyloxypyrrolidine derivatives and use thereof as ligands of v1b or both v1b and v1a receptors Download PDF

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Publication number
HRP20041231A2
HRP20041231A2 HR20041231A HRP20041231A HRP20041231A2 HR P20041231 A2 HRP20041231 A2 HR P20041231A2 HR 20041231 A HR20041231 A HR 20041231A HR P20041231 A HRP20041231 A HR P20041231A HR P20041231 A2 HRP20041231 A2 HR P20041231A2
Authority
HR
Croatia
Prior art keywords
compound
formula
dimethoxyphenyl
methoxyphenyl
sulfonyl
Prior art date
Application number
HR20041231A
Other languages
English (en)
Croatian (hr)
Inventor
Aulombard Alain
Garcia Georges
Pradines Antoine
Serradeil - Le Gal Claudine
Wagnon Jean
Original Assignee
Sanofi-Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi-Aventis filed Critical Sanofi-Aventis
Publication of HRP20041231A2 publication Critical patent/HRP20041231A2/hr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/06—Antiabortive agents; Labour repressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Neurosurgery (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Gynecology & Obstetrics (AREA)
  • Emergency Medicine (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HR20041231A 2002-07-19 2003-07-17 Acyloxypyrrolidine derivatives and use thereof as ligands of v1b or both v1b and v1a receptors HRP20041231A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0209242A FR2842527B1 (fr) 2002-07-19 2002-07-19 Derives d'acyloxypyrolidine, leur preparation et leur application en therapeutique
PCT/FR2003/002262 WO2004009585A2 (fr) 2002-07-19 2003-07-17 Derives d'acyloxypyrrolidine et leur utilisation en tant que ligands des recepteurs v1b et v1a de avp

Publications (1)

Publication Number Publication Date
HRP20041231A2 true HRP20041231A2 (en) 2005-02-28

Family

ID=29797610

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20041231A HRP20041231A2 (en) 2002-07-19 2003-07-17 Acyloxypyrrolidine derivatives and use thereof as ligands of v1b or both v1b and v1a receptors

Country Status (27)

Country Link
US (1) US7202267B2 (de)
EP (1) EP1525198B1 (de)
JP (1) JP4264414B2 (de)
CN (1) CN100425608C (de)
AR (1) AR040571A1 (de)
AT (1) ATE312092T1 (de)
AU (1) AU2003271815B8 (de)
BR (1) BR0312800A (de)
CA (1) CA2492224A1 (de)
DE (1) DE60302670T2 (de)
DK (1) DK1525198T3 (de)
EA (1) EA008444B1 (de)
ES (1) ES2254962T3 (de)
FR (1) FR2842527B1 (de)
HR (1) HRP20041231A2 (de)
IL (1) IL165942A (de)
IS (1) IS2487B (de)
ME (1) MEP12408A (de)
MX (1) MXPA05000822A (de)
NO (1) NO20050292L (de)
NZ (1) NZ537615A (de)
PL (1) PL375309A1 (de)
RS (1) RS20050018A (de)
TW (1) TWI274751B (de)
UA (1) UA78805C2 (de)
WO (1) WO2004009585A2 (de)
ZA (1) ZA200500478B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4618127B2 (ja) 2003-08-28 2011-01-26 大正製薬株式会社 １，３−ジヒドロ−２ｈ−インドール−２−オン誘導体
TW200643015A (en) 2005-03-11 2006-12-16 Akzo Nobel Nv 2-(4-oxo-4H-quinazolin-3-yl)acetamide derivatives
DE102005015957A1 (de) * 2005-03-31 2006-10-05 Abbott Gmbh & Co. Kg Substituierte Oxindol-Derivate, diese enthaltende Arzneimittel und deren Verwendung
US8350043B2 (en) 2005-06-07 2013-01-08 Pharmacopeia, Inc. Azinone and diazinone V3 inhibitors for depression and stress disorders
CA2663161C (en) 2006-09-11 2014-10-28 N.V. Organon Quinazolinone and isoquinolinone acetamide derivatives
CN103864658B (zh) * 2014-03-06 2016-06-15 南京工业大学 氮杂环丁酮衍生物及其制备方法与应用
CN104447489B (zh) * 2014-12-29 2017-01-11 南京工业大学 3,4-二芳基马来酰亚胺衍生物及其制备方法与应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2804114B1 (fr) * 2000-01-25 2002-03-08 Sanofi Synthelabo Nouveaux derives de 1,3-dihydro-2h-indol-2-one, un procede pour leur preparation et les compositions pharmaceutiques en contenant

Also Published As

Publication number Publication date
EP1525198B1 (de) 2005-12-07
ZA200500478B (en) 2006-07-26
AU2003271815A1 (en) 2004-02-09
CA2492224A1 (en) 2004-01-29
CN1681806A (zh) 2005-10-12
TW200410957A (en) 2004-07-01
AR040571A1 (es) 2005-04-13
JP4264414B2 (ja) 2009-05-20
JP2005537271A (ja) 2005-12-08
UA78805C2 (en) 2007-04-25
DE60302670T2 (de) 2006-09-07
EA200500032A1 (ru) 2005-08-25
EP1525198A2 (de) 2005-04-27
US7202267B2 (en) 2007-04-10
HK1074444A1 (en) 2005-11-11
FR2842527A1 (fr) 2004-01-23
TWI274751B (en) 2007-03-01
CN100425608C (zh) 2008-10-15
ATE312092T1 (de) 2005-12-15
FR2842527B1 (fr) 2005-01-28
IS2487B (is) 2008-12-15
PL375309A1 (en) 2005-11-28
IL165942A0 (en) 2006-01-15
AU2003271815B2 (en) 2009-03-12
IS7641A (is) 2005-01-12
WO2004009585A2 (fr) 2004-01-29
BR0312800A (pt) 2005-04-19
WO2004009585A3 (fr) 2004-05-06
US20050192335A1 (en) 2005-09-01
NZ537615A (en) 2006-11-30
AU2003271815B8 (en) 2009-04-30
MXPA05000822A (es) 2005-08-29
IL165942A (en) 2010-04-15
DE60302670D1 (de) 2006-01-12
NO20050292L (no) 2005-04-19
RS20050018A (sr) 2007-06-04
EA008444B1 (ru) 2007-06-29
DK1525198T3 (da) 2006-04-18
MEP12408A (en) 2010-06-10
ES2254962T3 (es) 2006-06-16

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