HRP20060402A2 - Derivati piridina alkilnih oksindola kao 5-ht7 receptorski aktivni agensi - Google Patents
Derivati piridina alkilnih oksindola kao 5-ht7 receptorski aktivni agensiInfo
- Publication number
- HRP20060402A2 HRP20060402A2 HR20060402A HRP20060402A HRP20060402A2 HR P20060402 A2 HRP20060402 A2 HR P20060402A2 HR 20060402 A HR20060402 A HR 20060402A HR P20060402 A HRP20060402 A HR P20060402A HR P20060402 A2 HRP20060402 A2 HR P20060402A2
- Authority
- HR
- Croatia
- Prior art keywords
- alkyl
- active agents
- oxindoles
- pyridine derivatives
- receptor active
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU0400956A HU0400956D0 (en) | 2004-05-11 | 2004-05-11 | Pyridine derivatives of alkyl oxindoles |
| HU0500462A HUP0500462A3 (en) | 2005-05-05 | 2005-05-05 | Pyridine derivatives of alkyloxindoles as 5ht7 receptor active agents |
| PCT/HU2005/000047 WO2005108388A1 (en) | 2004-05-11 | 2005-05-10 | Pyridine derivatives of alkyl oxindoles as 5-ht7 receptor active agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20060402A2 true HRP20060402A2 (hr) | 2007-06-30 |
Family
ID=89985996
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20060402A HRP20060402A2 (hr) | 2004-05-11 | 2005-05-10 | Derivati piridina alkilnih oksindola kao 5-ht7 receptorski aktivni agensi |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US20070265300A1 (pl) |
| EP (1) | EP1751134A1 (pl) |
| JP (1) | JP2007537225A (pl) |
| KR (1) | KR20070011552A (pl) |
| AU (1) | AU2005240841A1 (pl) |
| BG (1) | BG109767A (pl) |
| CA (1) | CA2565061A1 (pl) |
| CZ (1) | CZ2006769A3 (pl) |
| EA (1) | EA010154B1 (pl) |
| HR (1) | HRP20060402A2 (pl) |
| IL (1) | IL178891A0 (pl) |
| MX (1) | MXPA06012991A (pl) |
| NO (1) | NO20065696L (pl) |
| NZ (1) | NZ551543A (pl) |
| PL (1) | PL381612A1 (pl) |
| RS (1) | RS20060619A (pl) |
| SK (1) | SK51052006A3 (pl) |
| WO (1) | WO2005108388A1 (pl) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106243088B (zh) | 2015-06-03 | 2019-01-04 | 广东东阳光药业有限公司 | 取代的哌嗪化合物及其使用方法和用途 |
| ES2808920T3 (es) | 2015-11-06 | 2021-03-02 | Hoffmann La Roche | Derivados de indolin-2-ona |
| EP3371169B1 (en) * | 2015-11-06 | 2019-07-17 | H. Hoffnabb-La Roche Ag | Indolin-2-one derivatives for use in the treatment of cns and related disorders |
| CN108137561B (zh) | 2015-11-06 | 2021-03-26 | 豪夫迈·罗氏有限公司 | 二氢吲哚-2-酮衍生物 |
| CN108137555B (zh) * | 2015-11-06 | 2021-02-19 | 豪夫迈·罗氏有限公司 | 可用于治疗cns疾病的二氢吲哚-2-酮衍生物 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8830312D0 (en) * | 1988-12-28 | 1989-02-22 | Lundbeck & Co As H | Heterocyclic compounds |
| ES2243999T3 (es) * | 1996-06-28 | 2005-12-01 | Meiji Seika Kaisha Ltd. | Compuestos de tetrahidrobencindol. |
| WO1998008816A1 (en) * | 1996-08-26 | 1998-03-05 | Meiji Seika Kaisha, Ltd. | Oxindole derivatives and psychotropic drugs |
| ZA9711376B (en) * | 1996-12-20 | 1998-07-21 | Lundbeck & Co As H | Indole or dihydroindole derivatives |
| US6498251B1 (en) * | 1997-12-25 | 2002-12-24 | Meiji Seika Kaisha, Ltd. | Tetrahydrobenzindole derivatives |
| JPH11189585A (ja) * | 1997-12-25 | 1999-07-13 | Meiji Seika Kaisha Ltd | 5−ht7受容体結合能を有するテトラヒドロベンズインドール誘導体 |
| US6407112B1 (en) * | 1998-04-22 | 2002-06-18 | Meiji Seika Kaisha, Ltd. | Optically active tetrahydrobenzindole derivative |
| JP2004231514A (ja) * | 2000-08-31 | 2004-08-19 | Meiji Seika Kaisha Ltd | 5−ht7受容体結合能を有し、かつ代謝的に安定なテトラヒドロベンズインドール誘導体 |
| AR035521A1 (es) * | 2000-12-22 | 2004-06-02 | Lundbeck & Co As H | Derivados de 3-indolina y composicion farmaceutica que los comprende |
| AU2003257407A1 (en) * | 2002-08-29 | 2004-03-19 | H. Lundbeck A/S | S-(+)-3-{1-(2-(2,3-dihydro-1h-indol-3-yl)ethyl)-3,6-dihydro-2h-pyridin-4-yl}-6-chloro-1h-indole and acid addition salts thereof |
| WO2005108390A1 (en) * | 2004-05-11 | 2005-11-17 | Egis Gyógyszergyár Nyrt. | Indol-2-one derivatives for the treatment of central nervous disorders, gastrointestinal disorders and cardiovascular disorders |
-
2005
- 2005-05-10 EP EP05745441A patent/EP1751134A1/en not_active Withdrawn
- 2005-05-10 JP JP2007512355A patent/JP2007537225A/ja active Pending
- 2005-05-10 US US11/596,472 patent/US20070265300A1/en not_active Abandoned
- 2005-05-10 CA CA002565061A patent/CA2565061A1/en not_active Abandoned
- 2005-05-10 RS RSP-2006/0619A patent/RS20060619A/sr unknown
- 2005-05-10 HR HR20060402A patent/HRP20060402A2/xx not_active Application Discontinuation
- 2005-05-10 NZ NZ551543A patent/NZ551543A/en unknown
- 2005-05-10 PL PL381612A patent/PL381612A1/pl not_active Application Discontinuation
- 2005-05-10 SK SK5105-2006A patent/SK51052006A3/sk unknown
- 2005-05-10 AU AU2005240841A patent/AU2005240841A1/en not_active Abandoned
- 2005-05-10 WO PCT/HU2005/000047 patent/WO2005108388A1/en not_active Ceased
- 2005-05-10 CZ CZ20060769A patent/CZ2006769A3/cs unknown
- 2005-05-10 KR KR1020067025137A patent/KR20070011552A/ko not_active Withdrawn
- 2005-05-10 MX MXPA06012991A patent/MXPA06012991A/es not_active Application Discontinuation
- 2005-05-10 EA EA200602081A patent/EA010154B1/ru not_active IP Right Cessation
-
2006
- 2006-10-26 IL IL178891A patent/IL178891A0/en unknown
- 2006-12-11 NO NO20065696A patent/NO20065696L/no not_active Application Discontinuation
- 2006-12-11 BG BG109767A patent/BG109767A/bg unknown
-
2009
- 2009-07-28 US US12/510,872 patent/US20090306144A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2005240841A1 (en) | 2005-11-17 |
| NZ551543A (en) | 2009-12-24 |
| US20070265300A1 (en) | 2007-11-15 |
| BG109767A (bg) | 2008-05-30 |
| KR20070011552A (ko) | 2007-01-24 |
| NO20065696L (no) | 2007-02-08 |
| US20090306144A1 (en) | 2009-12-10 |
| PL381612A1 (pl) | 2007-06-11 |
| CZ2006769A3 (cs) | 2007-03-14 |
| CA2565061A1 (en) | 2005-11-17 |
| EA200602081A1 (ru) | 2007-04-27 |
| EA010154B1 (ru) | 2008-06-30 |
| MXPA06012991A (es) | 2007-05-04 |
| IL178891A0 (en) | 2007-03-08 |
| WO2005108388A1 (en) | 2005-11-17 |
| JP2007537225A (ja) | 2007-12-20 |
| EP1751134A1 (en) | 2007-02-14 |
| RS20060619A (sr) | 2008-06-05 |
| SK51052006A3 (sk) | 2007-05-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A1OB | Publication of a patent application | ||
| AIPI | Request for the grant of a patent on the basis of a substantive examination of a patent application | ||
| ODRP | Renewal fee for the maintenance of a patent |
Payment date: 20090504 Year of fee payment: 5 |
|
| OBST | Application withdrawn |