HRP20060403A2 - Indol-2-one derivatives for the treatment of central nervous disorders, gastrointestinal disorders and cardiovascular disorders - Google Patents
Indol-2-one derivatives for the treatment of central nervous disorders, gastrointestinal disorders and cardiovascular disordersInfo
- Publication number
- HRP20060403A2 HRP20060403A2 HR20060403A HRP20060403A HRP20060403A2 HR P20060403 A2 HRP20060403 A2 HR P20060403A2 HR 20060403 A HR20060403 A HR 20060403A HR P20060403 A HRP20060403 A HR P20060403A HR P20060403 A2 HRP20060403 A2 HR P20060403A2
- Authority
- HR
- Croatia
- Prior art keywords
- disorders
- derivatives
- treatment
- central nervous
- indol
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU0400955A HU0400955D0 (en) | 2004-05-11 | 2004-05-11 | Pyridine derivatives of dialkyl oxindoles |
| HU0500463A HUP0500463A3 (en) | 2005-05-05 | 2005-05-05 | Pyridine derivatives of dialkyl-oxindoles |
| PCT/HU2005/000051 WO2005108390A1 (en) | 2004-05-11 | 2005-05-11 | Indol-2-one derivatives for the treatment of central nervous disorders, gastrointestinal disorders and cardiovascular disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20060403A2 true HRP20060403A2 (en) | 2007-04-30 |
Family
ID=89985998
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20060403A HRP20060403A2 (en) | 2004-05-11 | 2005-05-11 | Indol-2-one derivatives for the treatment of central nervous disorders, gastrointestinal disorders and cardiovascular disorders |
| HR20080129T HRP20080129T3 (en) | 2004-05-11 | 2005-05-11 | Indol-2-one derivatives for the treatment of central nervous disorders, gastrointestinal disorders and cardiovascular disorders |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20080129T HRP20080129T3 (en) | 2004-05-11 | 2005-05-11 | Indol-2-one derivatives for the treatment of central nervous disorders, gastrointestinal disorders and cardiovascular disorders |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US20070232662A1 (pl) |
| EP (1) | EP1751138B9 (pl) |
| JP (1) | JP2007537228A (pl) |
| KR (1) | KR20070014189A (pl) |
| AT (1) | ATE382045T1 (pl) |
| AU (1) | AU2005240844A1 (pl) |
| BG (1) | BG109770A (pl) |
| CA (1) | CA2566426A1 (pl) |
| CZ (1) | CZ2006772A3 (pl) |
| DE (1) | DE602005004024T2 (pl) |
| EA (1) | EA010865B1 (pl) |
| ES (1) | ES2299033T3 (pl) |
| HR (2) | HRP20060403A2 (pl) |
| IL (1) | IL179030A0 (pl) |
| MX (1) | MXPA06013065A (pl) |
| NO (1) | NO20065661L (pl) |
| PL (2) | PL1751138T3 (pl) |
| PT (1) | PT1751138E (pl) |
| RS (1) | RS20060622A (pl) |
| SK (1) | SK51062006A3 (pl) |
| WO (1) | WO2005108390A1 (pl) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SK51052006A3 (sk) * | 2004-05-11 | 2007-05-03 | Egis Gy�gyszergy�r Nyrt. | Pyridínové deriváty alkyloxindolov ako aktívne látky voči 5-HT7 receptoru |
| PT1776339E (pt) * | 2004-05-11 | 2009-09-16 | Egis Gyogyszergyar Nyrt | Derivados de 3-(((4-fenil)-piperazin-1-il)-alquil)-3-alquil- 1,3-di-hidro-2h-indol-2-ona e compostos relacionados para o tratamento de desordens do sistema nervoso central |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8830312D0 (en) * | 1988-12-28 | 1989-02-22 | Lundbeck & Co As H | Heterocyclic compounds |
| EP1081136A4 (en) * | 1998-04-22 | 2002-07-03 | Meiji Seika Kaisha | OPTICALLY ACTIVE TETRAHYDROBENZINDOLES DERIVATIVES |
| FR2779429B1 (fr) * | 1998-06-03 | 2000-07-13 | Synthelabo | Derives d'oxindole, leurs preparations et leurs applications en therapeutique |
| AR035521A1 (es) * | 2000-12-22 | 2004-06-02 | Lundbeck & Co As H | Derivados de 3-indolina y composicion farmaceutica que los comprende |
-
2005
- 2005-05-11 AT AT05745439T patent/ATE382045T1/de not_active IP Right Cessation
- 2005-05-11 EA EA200602082A patent/EA010865B1/ru not_active IP Right Cessation
- 2005-05-11 MX MXPA06013065A patent/MXPA06013065A/es active IP Right Grant
- 2005-05-11 CA CA002566426A patent/CA2566426A1/en not_active Abandoned
- 2005-05-11 US US11/596,471 patent/US20070232662A1/en not_active Abandoned
- 2005-05-11 SK SK5106-2006A patent/SK51062006A3/sk not_active Application Discontinuation
- 2005-05-11 CZ CZ20060772A patent/CZ2006772A3/cs unknown
- 2005-05-11 HR HR20060403A patent/HRP20060403A2/xx not_active Application Discontinuation
- 2005-05-11 DE DE602005004024T patent/DE602005004024T2/de not_active Expired - Fee Related
- 2005-05-11 ES ES05745439T patent/ES2299033T3/es not_active Expired - Lifetime
- 2005-05-11 WO PCT/HU2005/000051 patent/WO2005108390A1/en not_active Ceased
- 2005-05-11 HR HR20080129T patent/HRP20080129T3/xx unknown
- 2005-05-11 EP EP05745439A patent/EP1751138B9/en not_active Expired - Lifetime
- 2005-05-11 JP JP2007512358A patent/JP2007537228A/ja active Pending
- 2005-05-11 PL PL05745439T patent/PL1751138T3/pl unknown
- 2005-05-11 PT PT05745439T patent/PT1751138E/pt unknown
- 2005-05-11 KR KR1020067025313A patent/KR20070014189A/ko not_active Withdrawn
- 2005-05-11 AU AU2005240844A patent/AU2005240844A1/en not_active Abandoned
- 2005-05-11 PL PL381614A patent/PL381614A1/pl not_active Application Discontinuation
- 2005-05-11 RS RSP-2006/0622A patent/RS20060622A/sr unknown
-
2006
- 2006-11-02 IL IL179030A patent/IL179030A0/en unknown
- 2006-12-06 NO NO20065661A patent/NO20065661L/no not_active Application Discontinuation
- 2006-12-11 BG BG109770A patent/BG109770A/bg unknown
-
2009
- 2009-07-09 US US12/500,335 patent/US20090281137A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| PL381614A1 (pl) | 2007-06-11 |
| BG109770A (bg) | 2008-05-30 |
| NO20065661L (no) | 2007-02-08 |
| HRP20080129T3 (en) | 2008-04-30 |
| US20090281137A1 (en) | 2009-11-12 |
| US20070232662A1 (en) | 2007-10-04 |
| DE602005004024D1 (de) | 2008-02-07 |
| RS20060622A (sr) | 2008-06-05 |
| PL1751138T3 (pl) | 2008-05-30 |
| EP1751138B1 (en) | 2007-12-26 |
| EP1751138B9 (en) | 2008-11-12 |
| CZ2006772A3 (cs) | 2007-03-14 |
| ATE382045T1 (de) | 2008-01-15 |
| AU2005240844A1 (en) | 2005-11-17 |
| MXPA06013065A (es) | 2007-05-04 |
| CA2566426A1 (en) | 2005-11-17 |
| WO2005108390A1 (en) | 2005-11-17 |
| ES2299033T3 (es) | 2008-05-16 |
| DE602005004024T2 (de) | 2008-12-24 |
| SK51062006A3 (sk) | 2007-04-05 |
| EP1751138A1 (en) | 2007-02-14 |
| KR20070014189A (ko) | 2007-01-31 |
| PT1751138E (pt) | 2008-02-25 |
| JP2007537228A (ja) | 2007-12-20 |
| IL179030A0 (en) | 2007-03-08 |
| EA200602082A1 (ru) | 2007-04-27 |
| EA010865B1 (ru) | 2008-12-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A1OB | Publication of a patent application | ||
| AIPI | Request for the grant of a patent on the basis of a substantive examination of a patent application | ||
| ODRP | Renewal fee for the maintenance of a patent |
Payment date: 20090504 Year of fee payment: 5 |
|
| OBST | Application withdrawn |