HRP20080667T3 - 4-phenyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline derivatives the treatment of infertility - Google Patents
4-phenyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline derivatives the treatment of infertilityInfo
- Publication number
- HRP20080667T3 HRP20080667T3 HR20080667T HRP20080667T HRP20080667T3 HR P20080667 T3 HRP20080667 T3 HR P20080667T3 HR 20080667 T HR20080667 T HR 20080667T HR P20080667 T HRP20080667 T HR P20080667T HR P20080667 T3 HRP20080667 T3 HR P20080667T3
- Authority
- HR
- Croatia
- Prior art keywords
- alkyl
- alkoxy
- alkylamino
- amino
- phenyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Diabetes (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05103735 | 2005-05-04 | ||
| PCT/EP2006/061972 WO2006117368A1 (en) | 2005-05-04 | 2006-05-02 | 4-phenyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline derivatives the treatment of infertility |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20080667T3 true HRP20080667T3 (en) | 2009-01-31 |
Family
ID=34939693
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20080667T HRP20080667T3 (en) | 2005-05-04 | 2006-05-02 | 4-phenyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline derivatives the treatment of infertility |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US8022218B2 (sr) |
| EP (1) | EP1881830B1 (sr) |
| JP (1) | JP5129737B2 (sr) |
| KR (1) | KR20080010426A (sr) |
| CN (1) | CN101212973B (sr) |
| AR (1) | AR057005A1 (sr) |
| AT (1) | ATE410166T1 (sr) |
| AU (1) | AU2006243868B2 (sr) |
| BR (1) | BRPI0611120A2 (sr) |
| CA (1) | CA2606683C (sr) |
| CY (1) | CY1108632T1 (sr) |
| DE (1) | DE602006003094D1 (sr) |
| DK (1) | DK1881830T3 (sr) |
| ES (1) | ES2314908T3 (sr) |
| HR (1) | HRP20080667T3 (sr) |
| IL (1) | IL186748A (sr) |
| MX (1) | MX2007013751A (sr) |
| NO (1) | NO20075617L (sr) |
| NZ (1) | NZ562686A (sr) |
| PE (1) | PE20061363A1 (sr) |
| PL (1) | PL1881830T3 (sr) |
| PT (1) | PT1881830E (sr) |
| RS (1) | RS50707B (sr) |
| RU (1) | RU2412170C2 (sr) |
| SI (1) | SI1881830T1 (sr) |
| TW (1) | TW200719894A (sr) |
| UA (1) | UA92007C2 (sr) |
| WO (1) | WO2006117368A1 (sr) |
| ZA (1) | ZA200709090B (sr) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0520259A2 (pt) * | 2005-05-04 | 2009-09-15 | Organon Nv | composto derivado de diidropiridina ou um sal farmaceuticamente aceitável do mesmo, composição farmacêutica, e, uso do composto |
| UA92009C2 (ru) * | 2005-05-04 | 2010-09-27 | Н.В. Органон | Производные 4-фенил-5-оксо-1,4,5,6,7,8-гексагидрохинолина для лечения бесплодия |
| UA92008C2 (en) * | 2005-05-04 | 2010-09-27 | Н.В. Органон | 4-PHENYL-5-OXO-l,4,5,6,7,8-HEXAHYDROQUINOLINE DERIVATIVES AS MEDICAMENTS FOR THE TREATMENT OF INFERTILITY |
| TW200944523A (en) | 2008-02-08 | 2009-11-01 | Organon Nv | (Dihydro)pyrrolo[2,1-a]isoquinolines |
| US8071587B2 (en) | 2009-05-27 | 2011-12-06 | N. V. Organon | (Dihydro)imidazoiso[5,1-A]quinolines |
| US8431564B2 (en) | 2009-07-29 | 2013-04-30 | Merck Sharp & Dohme B.V. | Ring-annulated dihydropyrrolo[2,1-α]isoquinolines |
| TW201116531A (en) | 2009-07-29 | 2011-05-16 | Organon Nv | Ring-annulated dihydropyrrolo[2,1-a]isoquinolines |
| TW201116515A (en) | 2009-07-31 | 2011-05-16 | Organon Nv | Dihydrobenzoindazoles |
| EP2694472B1 (en) | 2011-04-05 | 2020-03-11 | Takeda Pharmaceutical Company Limited | Sulfonamide derivative and use thereof |
| US20150296779A1 (en) * | 2012-11-28 | 2015-10-22 | Stichting Dienst Landbouwkundig Onderzoek | Substituted dihydropyridines for somatic embryogenesis in plants |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1070162B (de) | 1959-12-03 | Farbwerke Hoechst Aktiengesellschaft vormals Meister Lucius &. Brüning, Frankfurt/M | Verfahren zur Herstellung von 5 - Brom - 3 - nitro - 4 - hydroxybenzaldehyd bzw. 5 - Chlor - 3 - nitro - 4 - hydroxybenzaldehyd | |
| GB9318935D0 (en) | 1992-10-20 | 1993-10-27 | Zeneca Ltd | Heterocyclic derivatives |
| US5455253A (en) * | 1992-10-20 | 1995-10-03 | Zeneca Limited | Heterocyclic derivatives |
| DE4430639A1 (de) * | 1994-08-29 | 1996-03-07 | Bayer Ag | Verwendung von 5-substituierten Pyridin- und Hexahydrochinolin-3-carbonsäurederivaten |
| GB9515445D0 (en) * | 1995-07-27 | 1995-09-27 | Pharmacia Spa | Dihydropyridine and pyridine derivatives and process for their preparation |
| CA2229201A1 (en) * | 1995-10-19 | 1997-04-24 | Satoshi Sasaki | Quinoline derivatives, their production and use |
| US6593335B1 (en) | 1997-12-18 | 2003-07-15 | Abbott Laboratories | Potassium channel openers |
| CA2339018A1 (en) | 1998-08-07 | 2000-02-17 | Applied Research Systems Ars Holding N.V. | Fsh mimetics for the treatment of infertility |
| EP1307193A1 (en) | 2000-07-27 | 2003-05-07 | Affymax Research Institute | Agonists of follicle stimulating hormone activity |
| US8058441B2 (en) * | 2001-07-02 | 2011-11-15 | N.V. Organon | Tetrahydroquinoline derivatives |
| JP2003026630A (ja) | 2001-07-13 | 2003-01-29 | Taoka Chem Co Ltd | カラーカプラー中間体用カルボン酸クロリド類の製造法 |
| TWI322012B (en) | 2002-12-20 | 2010-03-21 | Organon Nv | Tetrahydroquinoline derivatives |
| BRPI0520259A2 (pt) * | 2005-05-04 | 2009-09-15 | Organon Nv | composto derivado de diidropiridina ou um sal farmaceuticamente aceitável do mesmo, composição farmacêutica, e, uso do composto |
| UA92008C2 (en) * | 2005-05-04 | 2010-09-27 | Н.В. Органон | 4-PHENYL-5-OXO-l,4,5,6,7,8-HEXAHYDROQUINOLINE DERIVATIVES AS MEDICAMENTS FOR THE TREATMENT OF INFERTILITY |
| UA92009C2 (ru) * | 2005-05-04 | 2010-09-27 | Н.В. Органон | Производные 4-фенил-5-оксо-1,4,5,6,7,8-гексагидрохинолина для лечения бесплодия |
-
2006
- 2006-02-05 UA UAA200711802A patent/UA92007C2/ru unknown
- 2006-05-02 JP JP2008509434A patent/JP5129737B2/ja not_active Expired - Fee Related
- 2006-05-02 HR HR20080667T patent/HRP20080667T3/xx unknown
- 2006-05-02 AU AU2006243868A patent/AU2006243868B2/en not_active Ceased
- 2006-05-02 MX MX2007013751A patent/MX2007013751A/es active IP Right Grant
- 2006-05-02 KR KR1020077026919A patent/KR20080010426A/ko not_active Ceased
- 2006-05-02 CN CN2006800237595A patent/CN101212973B/zh not_active Expired - Fee Related
- 2006-05-02 EP EP06743394A patent/EP1881830B1/en active Active
- 2006-05-02 AT AT06743394T patent/ATE410166T1/de active
- 2006-05-02 PL PL06743394T patent/PL1881830T3/pl unknown
- 2006-05-02 NZ NZ562686A patent/NZ562686A/en not_active IP Right Cessation
- 2006-05-02 PT PT06743394T patent/PT1881830E/pt unknown
- 2006-05-02 BR BRPI0611120-3A patent/BRPI0611120A2/pt not_active IP Right Cessation
- 2006-05-02 WO PCT/EP2006/061972 patent/WO2006117368A1/en not_active Ceased
- 2006-05-02 DE DE602006003094T patent/DE602006003094D1/de active Active
- 2006-05-02 RU RU2007144989/04A patent/RU2412170C2/ru not_active IP Right Cessation
- 2006-05-02 SI SI200630157T patent/SI1881830T1/sl unknown
- 2006-05-02 US US11/912,736 patent/US8022218B2/en active Active
- 2006-05-02 ES ES06743394T patent/ES2314908T3/es active Active
- 2006-05-02 RS RSP-2008/0582A patent/RS50707B/sr unknown
- 2006-05-02 DK DK06743394T patent/DK1881830T3/da active
- 2006-05-02 CA CA2606683A patent/CA2606683C/en not_active Expired - Fee Related
- 2006-05-03 TW TW095115774A patent/TW200719894A/zh unknown
- 2006-05-03 AR ARP060101779A patent/AR057005A1/es unknown
- 2006-05-03 PE PE2006000464A patent/PE20061363A1/es not_active Application Discontinuation
-
2007
- 2007-10-18 IL IL186748A patent/IL186748A/en not_active IP Right Cessation
- 2007-10-22 ZA ZA200709090A patent/ZA200709090B/xx unknown
- 2007-11-06 NO NO20075617A patent/NO20075617L/no not_active Application Discontinuation
-
2008
- 2008-12-22 CY CY20081101479T patent/CY1108632T1/el unknown
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