HRP20080677T3 - Uporaba 3,11 b-cis-dihidrotetrabenazina u liječenju simptoma huntington-ove bolesti - Google Patents
Uporaba 3,11 b-cis-dihidrotetrabenazina u liječenju simptoma huntington-ove bolestiInfo
- Publication number
- HRP20080677T3 HRP20080677T3 HR20080677T HRP20080677T HRP20080677T3 HR P20080677 T3 HRP20080677 T3 HR P20080677T3 HR 20080677 T HR20080677 T HR 20080677T HR P20080677 T HRP20080677 T HR P20080677T HR P20080677 T3 HRP20080677 T3 HR P20080677T3
- Authority
- HR
- Croatia
- Prior art keywords
- dihydrotetrabenazine
- cis
- treatment
- disease symptoms
- huntington disease
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0514501.6A GB0514501D0 (en) | 2005-07-14 | 2005-07-14 | Pharmaceutical compounds |
| PCT/GB2006/002593 WO2007007105A1 (fr) | 2005-07-14 | 2006-07-13 | Composes pharmaceutiques |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20080677T3 true HRP20080677T3 (hr) | 2009-02-28 |
Family
ID=34897233
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20080677T HRP20080677T3 (hr) | 2005-07-14 | 2006-07-13 | Uporaba 3,11 b-cis-dihidrotetrabenazina u liječenju simptoma huntington-ove bolesti |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US20080319000A1 (fr) |
| EP (2) | EP1885363B1 (fr) |
| JP (1) | JP2009501202A (fr) |
| KR (1) | KR20080030666A (fr) |
| CN (1) | CN101282726A (fr) |
| AT (2) | ATE522215T1 (fr) |
| AU (1) | AU2006268098B2 (fr) |
| CA (1) | CA2615077A1 (fr) |
| CY (1) | CY1108653T1 (fr) |
| DE (1) | DE602006002982D1 (fr) |
| DK (1) | DK1885363T3 (fr) |
| ES (1) | ES2314931T3 (fr) |
| GB (1) | GB0514501D0 (fr) |
| HR (1) | HRP20080677T3 (fr) |
| ME (1) | ME01629B (fr) |
| NZ (1) | NZ565522A (fr) |
| PL (1) | PL1885363T3 (fr) |
| PT (1) | PT1885363E (fr) |
| RS (1) | RS50626B (fr) |
| RU (1) | RU2409365C2 (fr) |
| SI (1) | SI1885363T1 (fr) |
| WO (1) | WO2007007105A1 (fr) |
| ZA (1) | ZA200800905B (fr) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2410947B (en) * | 2004-02-11 | 2008-09-17 | Cambridge Lab Ltd | Pharmaceutical compounds |
| GB0516168D0 (en) * | 2005-08-05 | 2005-09-14 | Cambridge Lab Ireland Ltd | Pharmaceutical compounds |
| DK2081929T3 (da) | 2006-11-08 | 2013-04-15 | Neurocrine Biosciences Inc | Substituerede 3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11B-hexahydro-2H-pyrido[2,1-A]isoquinolin-2-ol-forbindelser og fremgangsmåder angående disse |
| GB0810857D0 (en) * | 2008-06-13 | 2008-07-23 | Cambridge Lab Ireland Ltd | Pharmaceutical compounds |
| US20120208773A1 (en) * | 2008-08-12 | 2012-08-16 | Valeant International (Barbados) Srl | Pharmaceutical compositions with tetrabenazine |
| GB2462611A (en) * | 2008-08-12 | 2010-02-17 | Cambridge Lab | Pharmaceutical composition comprising tetrabenazine |
| US20110053866A1 (en) * | 2008-08-12 | 2011-03-03 | Biovail Laboratories International (Barbados) S.R.L. | Pharmaceutical compositions |
| GB2463451A (en) * | 2008-09-08 | 2010-03-17 | Cambridge Lab | 3, 11b cis-dihydrotetrabenazine compounds for use in the treatment of dementia |
| GB2463452A (en) * | 2008-09-08 | 2010-03-17 | Cambridge Lab | Desmethyl derivatives of tetrabenazine and pharmaceutical compositions thereof |
| GB2463283A (en) * | 2008-09-08 | 2010-03-10 | Cambridge Lab | 3,11b-cis-dihydrotetrabenazine for use in treating asthma |
| JP2013501810A (ja) * | 2009-08-12 | 2013-01-17 | ヴァリーント インターナショナル(バルバドス)エスアールエル | 医薬組成物 |
| CA2801061A1 (fr) * | 2010-06-01 | 2011-12-08 | Auspex Pharmaceuticals, Inc. | Inhibiteurs benzoquinolone de vmat2 |
| WO2012095548A2 (fr) | 2011-01-13 | 2012-07-19 | Centro De Investigación Biomédica En Red De Enfermedades Neurodegenerativas (Ciberned) | Composés pour le traitement de maladies neurodégénératives |
| GB201705304D0 (en) | 2017-04-01 | 2017-05-17 | Adeptio Pharmaceuticals Ltd | Pharmaceutical compositions |
| GB201705302D0 (en) | 2017-04-01 | 2017-05-17 | Adeptio Pharmaceuticals Ltd | Pharmaceutical compositions |
| GB201705305D0 (en) | 2017-04-01 | 2017-05-17 | Adeptio Pharmaceuticals Ltd | Pharmaceutical compositions |
| GB201705306D0 (en) | 2017-04-01 | 2017-05-17 | Adeptio Pharmaceuticals Ltd | Pharmaceutical compositions |
| GB201705303D0 (en) | 2017-04-01 | 2017-05-17 | Adeptio Pharmaceuticals Ltd | Pharmaceutical compositions |
| RU2768738C2 (ru) * | 2017-04-01 | 2022-03-24 | Адептио Фармасьютикалз Лимитед | ПРИМЕНЕНИЕ (-)-α-ДИГИДРОТЕТРАБЕНАЗИНА ИЛИ ЕГО КОМБИНАЦИИ С (+)-α-ДИГИДРОТЕТРАБЕНАЗИНОМ В ЛЕЧЕНИИ ГИПЕРКИНЕТИЧЕСКОГО ДВИГАТЕЛЬНОГО РАССТРОЙСТВА, А ТАКЖЕ СООТВЕТСТВУЮЩИЕ СПОСОБЫ |
| DK3784237T3 (da) | 2018-04-25 | 2024-01-08 | Shinkei Therapeutics Inc | Indretning til transdermal levering af tetrabenazin |
| GB201808464D0 (en) | 2018-05-23 | 2018-07-11 | Adeptio Pharmaceuticals Ltd | Pharmaceutical compounds for use in treating huntington's disease |
| JP2022541021A (ja) * | 2019-07-16 | 2022-09-21 | ラッシュ・ユニバーシティ・メディカル・センター | 神経変性障害を治療するためのベンゾエート含有組成物の使用 |
Family Cites Families (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2843591A (en) * | 1958-07-15 | Method for preparing same | ||
| US2954382A (en) * | 1960-09-27 | Xpreparation of hexahydrobenzoquinol- | ||
| US3095419A (en) * | 1963-06-25 | Process for preparing z-oxo-j- | ||
| US3314966A (en) * | 1967-04-18 | Substituted benzo[a]quinolizines | ||
| US3132147A (en) * | 1964-05-05 | |||
| US3209005A (en) * | 1965-09-28 | Hexahydro-llbh-benzo[a] quinolizines and processes therefor | ||
| US3123609A (en) * | 1964-03-03 | Benzo | ||
| US3009918A (en) * | 1961-11-21 | Chz ch | ||
| US3159638A (en) * | 1964-12-01 | Xcha-chj | ||
| US2830993A (en) * | 1958-04-15 | Quinolizine derivatives | ||
| US3079395A (en) * | 1963-02-26 | Novel z-oxq-benzoquinoliaine | ||
| US3053845A (en) * | 1962-09-11 | Benzofykedocolines | ||
| US3045021A (en) * | 1959-09-24 | 1962-07-17 | Hoffmann La Roche | Preparation of substituted 2-oxobenzoquinolizines |
| GB999092A (en) * | 1959-11-24 | 1965-07-21 | Wellcome Found | Method for making benzo(a)-quinolizine derivatives |
| US3375254A (en) * | 1961-09-29 | 1968-03-26 | Burroughs Wellcome Co | Manufacture of 1, 2, 3, 4, 6, 7-hexahydro-2-oxo-11bh-benzo(a)quinolizines |
| US3105079A (en) * | 1961-12-29 | 1963-09-24 | Pfizer & Co C | 10-aminobenzopyridocolines |
| US3390152A (en) * | 1965-10-21 | 1968-06-25 | Abbott Lab | 9, 10-alkoxy-3-alkyl-2, 2-(dithiosubstituted)-benzoquinolizines |
| JPS4836303B1 (fr) * | 1968-12-27 | 1973-11-02 | ||
| US3635986A (en) * | 1969-12-22 | 1972-01-18 | Miles Lab | 2-substituted amino-hexahydrobenzo(a)quinolizines |
| YU264675A (en) * | 1974-10-23 | 1982-05-31 | Chinoin Gyogyszer Es Vegyeszet | Process for obtaining benzo (a)-quinolizidine derivatives |
| GB1513824A (en) * | 1975-05-22 | 1978-06-14 | Wyeth John & Brother Ltd | 1,3,4,6,7,11b-hexahydro-2h-benzo(a)quinolizine derivative |
| US4133812A (en) * | 1975-11-21 | 1979-01-09 | Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt. | Process for producing benzo (a) quinolizine derivatives |
| US4304913A (en) * | 1978-11-20 | 1981-12-08 | Miles Laboratories, Inc. | Trans-2-substituted-amido-hexahydrobenzo [A]quinolizines |
| US4353656A (en) * | 1980-10-14 | 1982-10-12 | Xerox Corporation | Moving coil, multiple energy print hammer system including a closed loop servo |
| US4778054A (en) * | 1982-10-08 | 1988-10-18 | Glaxo Group Limited | Pack for administering medicaments to patients |
| EP0211595B1 (fr) * | 1985-07-30 | 1991-11-13 | Glaxo Group Limited | Appareil pour administrer des médicaments à un patient |
| GB9004781D0 (en) * | 1990-03-02 | 1990-04-25 | Glaxo Group Ltd | Device |
| US6087376A (en) * | 1997-02-05 | 2000-07-11 | University Of Kentucky Research Foundation | Use of lobeline compounds in the treatment of central nervous system diseases and pathologies |
| FR2794742B1 (fr) * | 1999-06-11 | 2005-06-03 | Sanofi Synthelabo | Nouveaux derives du benzene, un procede pour leur preparation et les compositions pharmaceutiques les contenant |
| US6632666B2 (en) * | 2000-01-14 | 2003-10-14 | Biolife Solutions, Inc. | Normothermic, hypothermic and cryopreservation maintenance and storage of cells, tissues and organs in gel-based media |
| BR0110302A (pt) * | 2000-04-18 | 2003-01-14 | Agouron Pharma | Compostos de pirazol para inibição de proteìnas cinase, sal e pró-droga farmaceuticamente aceitável, metabólito farmaceuticamente ativo ou sal farmaceuticamente aceitável de metabólito, composição farmacêutica, método de tratamento de condição doentia em mamìferos mediada pela atividade de proteìna cinase, método de modulação ou inibição da atividade de um receptor de proteìna cinase |
| CA2673334C (fr) * | 2003-06-16 | 2013-11-12 | Andrx Pharmaceuticals, Llc | Composition orale a liberation prolongee |
| GB2410947B (en) * | 2004-02-11 | 2008-09-17 | Cambridge Lab Ltd | Pharmaceutical compounds |
| WO2006053067A2 (fr) * | 2004-11-09 | 2006-05-18 | Prestwick Pharmaceuticals, Inc. | Traitement de l'hypercinesie associant l'amantadine a un compose tetrabenazinique |
| KR100682506B1 (ko) * | 2005-01-18 | 2007-02-15 | (주)젠크로스 | 프라지콴텔, 또는 이의 염을 포함하는 약학 조성물 |
| GB0516168D0 (en) * | 2005-08-05 | 2005-09-14 | Cambridge Lab Ireland Ltd | Pharmaceutical compounds |
| GB2462611A (en) * | 2008-08-12 | 2010-02-17 | Cambridge Lab | Pharmaceutical composition comprising tetrabenazine |
| US20110053866A1 (en) * | 2008-08-12 | 2011-03-03 | Biovail Laboratories International (Barbados) S.R.L. | Pharmaceutical compositions |
| GB2463452A (en) * | 2008-09-08 | 2010-03-17 | Cambridge Lab | Desmethyl derivatives of tetrabenazine and pharmaceutical compositions thereof |
| GB2463283A (en) * | 2008-09-08 | 2010-03-10 | Cambridge Lab | 3,11b-cis-dihydrotetrabenazine for use in treating asthma |
| GB2463451A (en) * | 2008-09-08 | 2010-03-17 | Cambridge Lab | 3, 11b cis-dihydrotetrabenazine compounds for use in the treatment of dementia |
-
2005
- 2005-07-14 GB GBGB0514501.6A patent/GB0514501D0/en not_active Ceased
-
2006
- 2006-05-31 ME MEP-2008-916A patent/ME01629B/fr unknown
- 2006-07-13 KR KR1020087003481A patent/KR20080030666A/ko not_active Withdrawn
- 2006-07-13 ES ES06764942T patent/ES2314931T3/es active Active
- 2006-07-13 CN CNA2006800339758A patent/CN101282726A/zh active Pending
- 2006-07-13 PL PL06764942T patent/PL1885363T3/pl unknown
- 2006-07-13 DE DE602006002982T patent/DE602006002982D1/de active Active
- 2006-07-13 EP EP06764942A patent/EP1885363B1/fr active Active
- 2006-07-13 AT AT08017191T patent/ATE522215T1/de not_active IP Right Cessation
- 2006-07-13 ZA ZA200800905A patent/ZA200800905B/xx unknown
- 2006-07-13 DK DK06764942T patent/DK1885363T3/da active
- 2006-07-13 SI SI200630147T patent/SI1885363T1/sl unknown
- 2006-07-13 AT AT06764942T patent/ATE409481T1/de active
- 2006-07-13 AU AU2006268098A patent/AU2006268098B2/en not_active Ceased
- 2006-07-13 PT PT06764942T patent/PT1885363E/pt unknown
- 2006-07-13 RS RSP-2008/0492A patent/RS50626B/sr unknown
- 2006-07-13 NZ NZ565522A patent/NZ565522A/en not_active IP Right Cessation
- 2006-07-13 EP EP08017191A patent/EP2027861B1/fr active Active
- 2006-07-13 CA CA002615077A patent/CA2615077A1/fr not_active Abandoned
- 2006-07-13 HR HR20080677T patent/HRP20080677T3/xx unknown
- 2006-07-13 WO PCT/GB2006/002593 patent/WO2007007105A1/fr not_active Ceased
- 2006-07-13 RU RU2008105590/15A patent/RU2409365C2/ru not_active IP Right Cessation
- 2006-07-13 JP JP2008520952A patent/JP2009501202A/ja active Pending
- 2006-07-13 US US11/995,436 patent/US20080319000A1/en not_active Abandoned
-
2008
- 2008-12-22 CY CY20081101475T patent/CY1108653T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SI1885363T1 (sl) | 2009-02-28 |
| CN101282726A (zh) | 2008-10-08 |
| GB0514501D0 (en) | 2005-08-24 |
| ATE409481T1 (de) | 2008-10-15 |
| ES2314931T3 (es) | 2009-03-16 |
| RS50626B (sr) | 2010-06-30 |
| CY1108653T1 (el) | 2014-04-09 |
| EP2027861A1 (fr) | 2009-02-25 |
| RU2409365C2 (ru) | 2011-01-20 |
| PL1885363T3 (pl) | 2009-05-29 |
| EP2027861B1 (fr) | 2011-08-31 |
| RU2008105590A (ru) | 2009-08-20 |
| AU2006268098B2 (en) | 2011-02-17 |
| NZ565522A (en) | 2010-04-30 |
| ME01629B (fr) | 2010-06-30 |
| DK1885363T3 (da) | 2008-12-08 |
| US20080319000A1 (en) | 2008-12-25 |
| WO2007007105A1 (fr) | 2007-01-18 |
| PT1885363E (pt) | 2009-01-08 |
| AU2006268098A1 (en) | 2007-01-18 |
| EP1885363B1 (fr) | 2008-10-01 |
| ATE522215T1 (de) | 2011-09-15 |
| DE602006002982D1 (de) | 2008-11-13 |
| JP2009501202A (ja) | 2009-01-15 |
| KR20080030666A (ko) | 2008-04-04 |
| ZA200800905B (en) | 2010-04-28 |
| CA2615077A1 (fr) | 2007-01-18 |
| HK1111085A1 (en) | 2008-08-01 |
| EP1885363A1 (fr) | 2008-02-13 |
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