HRP20171970T1 - Oralno primijenjeni adsorbent koji sadrži aktivno ugljično vlakno - Google Patents

Oralno primijenjeni adsorbent koji sadrži aktivno ugljično vlakno Download PDF

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Publication number
HRP20171970T1
HRP20171970T1 HRP20171970TT HRP20171970T HRP20171970T1 HR P20171970 T1 HRP20171970 T1 HR P20171970T1 HR P20171970T T HRP20171970T T HR P20171970TT HR P20171970 T HRP20171970 T HR P20171970T HR P20171970 T1 HRP20171970 T1 HR P20171970T1
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Croatia
Prior art keywords
carbon fiber
active carbon
use according
syndrome
kidney disease
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HRP20171970TT
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English (en)
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Yasumi Nishiwaki
Takashi Murakami
Nobuaki Eto
Keiichiro Imaizumi
Akihito OHTAKI
Kenji Shimazaki
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Teijin Pharma Limited
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Publication of HRP20171970T1 publication Critical patent/HRP20171970T1/hr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/44—Elemental carbon, e.g. charcoal, carbon black
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/02—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material
    • B01J20/20—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material comprising free carbon; comprising carbon obtained by carbonising processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28002—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their physical properties
    • B01J20/28004—Sorbent size or size distribution, e.g. particle size
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28014—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their form
    • B01J20/28023—Fibres or filaments
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28054—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their surface properties or porosity
    • B01J20/28057—Surface area, e.g. B.E.T specific surface area
    • B01J20/28066—Surface area, e.g. B.E.T specific surface area being more than 1000 m2/g
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28054—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their surface properties or porosity
    • B01J20/28069—Pore volume, e.g. total pore volume, mesopore volume, micropore volume
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28054—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their surface properties or porosity
    • B01J20/28078—Pore diameter
    • B01J20/2808—Pore diameter being less than 2 nm, i.e. micropores or nanopores
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B32/00—Carbon; Compounds thereof
    • C01B32/30—Active carbon
    • C01B32/312—Preparation
    • C01B32/336—Preparation characterised by gaseous activating agents
    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01F—CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
    • D01F9/00—Artificial filaments or the like of other substances; Manufacture thereof; Apparatus specially adapted for the manufacture of carbon filaments
    • D01F9/08—Artificial filaments or the like of other substances; Manufacture thereof; Apparatus specially adapted for the manufacture of carbon filaments of inorganic material
    • D01F9/12—Carbon filaments; Apparatus specially adapted for the manufacture thereof
    • D01F9/14—Carbon filaments; Apparatus specially adapted for the manufacture thereof by decomposition of organic filaments

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Nanotechnology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • External Artificial Organs (AREA)
  • Medicinal Preparation (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Carbon And Carbon Compounds (AREA)

Claims (8)

1. Aktivno ugljično vlakno za uporabu u postupku liječenja ili prevencije bolesti bubrega ili komplikacija kod dijalize, naznačeno time da se aktivno ugljično vlakno daje oralno i postupak obuhvaća adsorpciju uremijskih toksina pomoću aktivnog ugljičnog vlakna.
2. Aktivno ugljično vlakno za uporabu prema zahtjevu 1, naznačeno time da aktivna ugljična vlakna imaju volumen mikropora od 0.1 do 2.0 mL/g.
3. Aktivno ugljično vlakno za uporabu prema zahtjevu 1 ili zahtjevu 2, naznačeno time da aktivna ugljična vlakna imaju dužinu vlakana od 15 µm ili više i volumen mikropora od 0.5 do 1.0 mL/g.
4. Aktivno ugljično vlakno za uporabu prema bilo kojem od zahtjeva 1 do 3, naznačeno time da postupak obuhvaća selektivnu adsorpciju uremijskih toksina pomoću aktivnog ugljičnog vlakna.
5. Aktivno ugljično vlakno za uporabu prema bilo kojem od zahtjeva 1 do 4, naznačeno time da se adsorbent primjenjuje u dnevnoj dozi od 1 do 3000 mg.
6. Aktivno ugljično vlakno za uporabu prema bilo kojem od zahtjeva 1 do 5, naznačeno time da aktivno ugljično vlakno promjer poprečnog presjeka od 5 do 50 µm, duljinu vlakna od 15 µm ili više, specifičnu površinu određenu BET postupkom od 1400 do 2700 m2/g, a ukupni volumen pora od 0.8 do 1.8 mL/g, te volumen mikropora od 0.5 do 1.0 mL/g.
7. Aktivno ugljično vlakno za uporabu prema zahtjevu 1, naznačeno time da je bolest bubrega odabrana od kronične bolesti bubrega, akutnog zatajenja bubrega, kroničnog pijelonefritisa, akutnog pijelonefritisa, kroničnog glomerulonefritisa, brzo progresivnog nefritičkog sindroma, nefrotičnog sindroma, nefroskleroze, intersticijalnog nefritisa, dijabetičke nefropatije, fokalne glomeruloskleroze, membranska nefropatije, sindroma policističnih bubrega, renovaskularne hipertenzije i sindroma hipertenzije, kao i sekundarnih bolesti bubrega povezanih s gore navedenim primarnim bolestima, hiperfosfatemija, hiperkalijemija, hiperuricemija, te hipernatrijemija koja prati kroničnu bolest bubrega.
8. Aktivno ugljično vlakno za uporabu prema zahtjevu 1, naznačeno time da komplikacija dijalize je pruritus, anemija, sindrom nemirnih nogu, zatajenje srca, arterioskleroza, amiloidoza u dijalizi, hiperfosfatemija, hiperkalijemija, i plućni edem.
HRP20171970TT 2011-10-07 2012-10-05 Oralno primijenjeni adsorbent koji sadrži aktivno ugljično vlakno HRP20171970T1 (hr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2011222949 2011-10-07
JP2012181466 2012-08-20
PCT/JP2012/075897 WO2013051680A1 (ja) 2011-10-07 2012-10-05 経口投与用吸着剤
EP12838141.5A EP2772261B1 (en) 2011-10-07 2012-10-05 Orally administered adsorbent containing activated carbon fiber

Publications (1)

Publication Number Publication Date
HRP20171970T1 true HRP20171970T1 (hr) 2018-02-09

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HRP20171970TT HRP20171970T1 (hr) 2011-10-07 2012-10-05 Oralno primijenjeni adsorbent koji sadrži aktivno ugljično vlakno

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US (1) US9682046B2 (hr)
EP (1) EP2772261B1 (hr)
JP (1) JP5781164B2 (hr)
KR (1) KR101890458B1 (hr)
CN (1) CN103841981B (hr)
AR (1) AR088255A1 (hr)
AU (1) AU2012319495B2 (hr)
BR (1) BR112014008230A2 (hr)
CA (1) CA2851215C (hr)
CY (1) CY1119877T1 (hr)
DK (1) DK2772261T3 (hr)
ES (1) ES2655176T3 (hr)
HR (1) HRP20171970T1 (hr)
HU (1) HUE036432T2 (hr)
IL (1) IL231680B (hr)
LT (1) LT2772261T (hr)
ME (1) ME02959B (hr)
MX (1) MX362027B (hr)
MY (1) MY167387A (hr)
NO (1) NO2772261T3 (hr)
PH (1) PH12014500718A1 (hr)
PL (1) PL2772261T3 (hr)
PT (1) PT2772261T (hr)
RS (1) RS56902B1 (hr)
RU (1) RU2583934C2 (hr)
SG (1) SG11201401320QA (hr)
SI (1) SI2772261T1 (hr)
SM (1) SMT201800180T1 (hr)
TW (1) TWI625122B (hr)
WO (1) WO2013051680A1 (hr)
ZA (1) ZA201402500B (hr)

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AU2012319495A1 (en) 2014-04-24
IL231680A0 (en) 2014-05-28
JPWO2013051680A1 (ja) 2015-03-30
CA2851215C (en) 2021-01-19
PL2772261T3 (pl) 2018-06-29
SI2772261T1 (en) 2018-02-28
AR088255A1 (es) 2014-05-21
PT2772261T (pt) 2018-01-08
AU2012319495B2 (en) 2017-07-20
CY1119877T1 (el) 2018-06-27
CN103841981B (zh) 2016-11-16
RS56902B1 (sr) 2018-05-31
US9682046B2 (en) 2017-06-20
ES2655176T3 (es) 2018-02-19
TWI625122B (zh) 2018-06-01
RU2583934C2 (ru) 2016-05-10
LT2772261T (lt) 2018-02-12
US20140242147A1 (en) 2014-08-28
SG11201401320QA (en) 2014-07-30
TW201328700A (zh) 2013-07-16
NO2772261T3 (hr) 2018-04-21
KR101890458B1 (ko) 2018-08-21
CN103841981A (zh) 2014-06-04
RU2014118448A (ru) 2015-11-20
BR112014008230A2 (pt) 2017-04-11
DK2772261T3 (en) 2018-01-08
JP5781164B2 (ja) 2015-09-16
EP2772261B1 (en) 2017-11-22
EP2772261A4 (en) 2015-09-30
MY167387A (en) 2018-08-16
EP2772261A1 (en) 2014-09-03
ME02959B (me) 2018-07-20
PH12014500718A1 (en) 2014-05-26
ZA201402500B (en) 2015-03-25
IL231680B (en) 2018-08-30
CA2851215A1 (en) 2013-04-11
MX2014003791A (es) 2014-07-09
MX362027B (es) 2019-01-04
WO2013051680A1 (ja) 2013-04-11
HUE036432T2 (hu) 2018-07-30
KR20140072077A (ko) 2014-06-12
NZ623528A (en) 2016-04-29
SMT201800180T1 (it) 2018-05-02

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