HRP940559B1 - Heterocyclic compounds - Google Patents

Heterocyclic compounds

Info

Publication number
HRP940559B1
HRP940559B1 HRP-1699/90A HRP940559A HRP940559B1 HR P940559 B1 HRP940559 B1 HR P940559B1 HR P940559 A HRP940559 A HR P940559A HR P940559 B1 HRP940559 B1 HR P940559B1
Authority
HR
Croatia
Prior art keywords
group
atom
zero
represent
hydrogen atom
Prior art date
Application number
HRP-1699/90A
Other languages
English (en)
Inventor
Claudio Bismara
Original Assignee
Claudio Bismara
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB898920337A external-priority patent/GB8920337D0/en
Priority claimed from GB909015484A external-priority patent/GB9015484D0/en
Application filed by Claudio Bismara filed Critical Claudio Bismara
Publication of HRP940559A2 publication Critical patent/HRP940559A2/xx
Publication of HRP940559B1 publication Critical patent/HRP940559B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/753—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
HRP-1699/90A 1989-09-08 1994-09-16 Heterocyclic compounds HRP940559B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB898920337A GB8920337D0 (en) 1989-09-08 1989-09-08 Heterocyclic compounds
GB909015484A GB9015484D0 (en) 1990-07-13 1990-07-13 Heterocyclic compounds
YU169990A YU48073B (sh) 1989-09-08 1990-09-06 Postupak za dobijanje heterocikličnih jedinjenja

Publications (2)

Publication Number Publication Date
HRP940559A2 HRP940559A2 (en) 1997-02-28
HRP940559B1 true HRP940559B1 (en) 1999-08-31

Family

ID=26295887

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP-1699/90A HRP940559B1 (en) 1989-09-08 1994-09-16 Heterocyclic compounds

Country Status (28)

Country Link
US (2) US5407931A (pl)
EP (2) EP0416952B1 (pl)
JP (2) JP3035325B2 (pl)
KR (1) KR100188175B1 (pl)
AT (2) ATE147394T1 (pl)
AU (1) AU632163B2 (pl)
CA (1) CA2024880C (pl)
CZ (1) CZ435990A3 (pl)
DD (1) DD298102A5 (pl)
DE (2) DE69030147T2 (pl)
DK (1) DK0416953T3 (pl)
ES (2) ES2100872T3 (pl)
FI (1) FI93450C (pl)
GR (1) GR3023647T3 (pl)
HR (1) HRP940559B1 (pl)
HU (1) HU218222B (pl)
IE (1) IE903257A1 (pl)
IL (1) IL95609A (pl)
MY (1) MY106980A (pl)
NO (1) NO175479C (pl)
NZ (1) NZ235223A (pl)
PL (1) PL166197B1 (pl)
PT (1) PT95247B (pl)
RU (1) RU2054006C1 (pl)
SG (1) SG73399A1 (pl)
SI (1) SI9011699A (pl)
SK (1) SK435990A3 (pl)
YU (1) YU48073B (pl)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU636913B2 (en) * 1989-10-11 1993-05-13 Takeda Chemical Industries Ltd. Tricyclic carbapenem compounds
GB9015485D0 (en) * 1990-07-13 1990-08-29 Glaxo Spa Heterocyclic derivatives
CA2067741C (en) * 1990-08-21 2002-01-01 Alcide Perboni 10(1-hydroxyethly)-11-oxo-1-azatricyclo[7.2.0.0.3.8]undec-2-ene-2-carboxylic acid esters and a process for preparing thereof
GB9104769D0 (en) * 1991-03-07 1991-04-17 Glaxo Spa Heterocyclic compounds
AP198A (en) * 1991-03-07 1992-06-30 Glaxo Spa Heterocyclic compounds.
GB9104832D0 (en) * 1991-03-07 1991-04-17 Glaxo Spa Heterocyclic compounds
GB9104838D0 (en) * 1991-03-07 1991-04-17 Glaxo Spa Heterocyclic compounds
GB9104833D0 (en) * 1991-03-07 1991-04-17 Glaxo Spa Heterocyclic compounds
CA2065079C (en) * 1991-04-05 2003-03-18 Michiyuki Sendai Polycyclic carbapenem compounds, their production and use
TW198035B (pl) * 1991-05-29 1993-01-11 Hoechst Ag
GB9218240D0 (en) * 1992-08-27 1992-10-14 Glaxo Spa Heterocyclic compounds
GB9218781D0 (en) * 1992-09-04 1992-10-21 Glaxo Spa Heterocyclic derivatives
GB9305805D0 (en) * 1993-03-20 1993-05-05 Glaxo Spa Chemical process
GB9305806D0 (en) * 1993-03-20 1993-05-05 Glaxo Spa Chemical compounds
US5849907A (en) * 1993-03-20 1998-12-15 Glaxo Wellcome Spa Chemical process
GB9305813D0 (en) * 1993-03-20 1993-05-05 Glaxo Spa Chemical process
GB9305853D0 (en) * 1993-03-20 1993-05-05 Glaxo Spa Chemical compounds
US5374630A (en) * 1993-06-10 1994-12-20 Merck & Co., Inc. Bridged carbapenem antibacterial compounds
US5372993A (en) * 1993-06-10 1994-12-13 Merck & Co., Inc. Bridged carbapenem compounds, compositions containing such compounds and methods of use
US5384317A (en) * 1993-08-02 1995-01-24 Merck & Co., Inc. Bridged biphenyl carbapenem compounds, compositions containing such compounds and methods of use
US5401735A (en) * 1993-08-02 1995-03-28 Merck & Co., Inc. Bridged biphenyl carbapenem antibacterial compounds
GB9323137D0 (en) * 1993-11-10 1994-01-05 Glaxo Spa Chemical compounds
GB9403729D0 (en) * 1994-02-26 1994-04-13 Glaxo Spa Amine derivatives
GB2287709A (en) * 1994-03-26 1995-09-27 Glaxo Spa Silylated azetidinone intermediates
GB9406074D0 (en) * 1994-03-26 1994-05-18 Glaxo Spa Chemical process
US5688786A (en) * 1994-04-01 1997-11-18 Microcide Pharmaceuticals, Inc. β-lactam antibiotics
US5698547A (en) * 1994-04-01 1997-12-16 Microcide Pharmaceuticals, Inc. Cephalosporin antibiotics
GB9516118D0 (en) * 1995-08-05 1995-10-04 Glaxo Spa Chemical process
GB9623684D0 (en) * 1996-11-14 1997-01-08 Glaxo Wellcome Spa Chemical compounds
US6531466B2 (en) 1996-11-14 2003-03-11 Glaxosmithkline Spa Tricyclic carbapenem compounds
JPH10168057A (ja) * 1996-12-12 1998-06-23 Takasago Internatl Corp シクロヘキシルアゼチジノン誘導体の製造法
AU5781498A (en) * 1997-02-10 1998-08-26 Sankyo Company Limited Tricyclic heterocyclic compounds
US5994343A (en) * 1997-10-02 1999-11-30 Merck & Co., Inc. Carbapenem antibacterial compounds, compositions containing such compounds and methods of treatment
US6207823B1 (en) * 1997-10-23 2001-03-27 Merck & Co., Inc. Carbapenem antibacterial compounds, compositions containing such compounds and methods of treatment
EP1032384A4 (en) * 1997-10-23 2001-11-21 Merck & Co Inc ANTIBACTERIAL CARBAPENEM COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING
US6271222B1 (en) 1998-05-28 2001-08-07 Merck & Co., Inc. Penem antibacterial compounds, compositions and methods of treatment
CN101367817B (zh) * 2007-06-26 2011-01-12 山东轩竹医药科技有限公司 含有环己烯酮甲酰氨基的碳青霉烯化合物
EP2085084A1 (en) * 2008-01-29 2009-08-05 LEK Pharmaceuticals D.D. Use of inhibitor of beta-lactamases and its combination with beta-lactam antibiotics
EP2135871A1 (en) * 2008-06-18 2009-12-23 LEK Pharmaceuticals D.D. New trinem antibiotics and inhibitors of beta-lactamases
DK3621609T3 (da) 2017-05-08 2022-08-29 Glaxosmithkline Ip Dev Ltd Sanfetrinem eller et salt eller ester deraf til anvendelse i behandling af mykobakterieinfektion

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4260627A (en) * 1978-10-24 1981-04-07 Merck & Co., Inc. 1-, 6- And 2-substituted-1-carba-2-penem-3-carboxylic acids
US4600713A (en) * 1979-12-03 1986-07-15 Merck & Co., Inc. 1-, 6- and 2-substituted-1-carba-2-penem-3-carboxylic acids
US4374849A (en) * 1981-09-14 1983-02-22 Merck & Co., Inc. 6-Amidocyclonocardicins
US4374848A (en) * 1981-09-14 1983-02-22 Merck & Co., Inc. 6-(1-Hydroxyethyl)cyclonocardicin
JPS61236785A (ja) * 1985-04-15 1986-10-22 Sankyo Co Ltd アゼチジノン誘導体
GB8607921D0 (en) 1986-04-01 1986-05-08 Fujisawa Pharmaceutical Co 3,4-disubstituted-2-azetidinone derivatives
AU636913B2 (en) * 1989-10-11 1993-05-13 Takeda Chemical Industries Ltd. Tricyclic carbapenem compounds

Also Published As

Publication number Publication date
EP0416952A3 (en) 1992-03-11
PL166197B1 (pl) 1995-04-28
AU6226590A (en) 1991-03-14
HU218222B (hu) 2000-06-28
EP0416952B1 (en) 1997-01-08
AU632163B2 (en) 1992-12-17
RU2054006C1 (ru) 1996-02-10
GR3023647T3 (en) 1997-09-30
US5407931A (en) 1995-04-18
NO903914L (no) 1991-03-11
NO903914D0 (no) 1990-09-07
ES2095860T3 (es) 1997-03-01
IE903257A1 (en) 1991-03-13
EP0416953B1 (en) 1997-03-12
SK278688B6 (sk) 1998-01-14
DD298102A5 (de) 1992-02-06
SK435990A3 (en) 1998-01-14
JP3018442B2 (ja) 2000-03-13
DK0416953T3 (da) 1997-09-01
JPH03167187A (ja) 1991-07-19
MY106980A (en) 1995-08-30
CZ285778B6 (cs) 1999-11-17
EP0416952A2 (en) 1991-03-13
YU169990A (sh) 1993-05-28
NO175479B (no) 1994-07-11
US5138048A (en) 1992-08-11
HU905826D0 (en) 1991-03-28
EP0416953A2 (en) 1991-03-13
YU48073B (sh) 1997-01-08
PT95247B (pt) 1997-06-30
FI93450C (fi) 1995-04-10
KR100188175B1 (ko) 1999-06-01
DE69029627T2 (de) 1997-04-24
CZ435990A3 (cs) 1999-11-17
HRP940559A2 (en) 1997-02-28
DE69030147D1 (de) 1997-04-17
PL286796A1 (en) 1991-08-26
KR910006291A (ko) 1991-04-29
EP0416953A3 (en) 1992-03-25
CA2024880A1 (en) 1991-03-09
JPH03169854A (ja) 1991-07-23
JP3035325B2 (ja) 2000-04-24
SI9011699A (en) 1997-10-31
NO175479C (no) 1994-10-19
ATE150022T1 (de) 1997-03-15
PT95247A (pt) 1991-06-25
IL95609A (en) 1995-03-30
ATE147394T1 (de) 1997-01-15
DE69029627D1 (de) 1997-02-20
ES2100872T3 (es) 1997-07-01
SG73399A1 (en) 2000-06-20
FI93450B (fi) 1994-12-30
DE69030147T2 (de) 1997-07-10
NZ235223A (en) 1992-11-25
HUT56105A (en) 1991-07-29
FI904423A0 (fi) 1990-09-07
CA2024880C (en) 2000-05-30

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