HU180230B - Process for producing dihydro- and hexahydrobenzopyranoxantenones - Google Patents

Process for producing dihydro- and hexahydrobenzopyranoxantenones Download PDF

Info

Publication number: HU180230B
Authority: HU; Hungary
Prior art keywords: formula; compound; dimethyl; preparation; xanthene
Prior art date: 1977-05-26

Application number

HU78EI777A

Other languages

German (de)

English (en)

Hungarian (hu)

Inventor

Michael E Flaugh

David A Hall

Richard E Heiney

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-05-26

Filing date

1978-02-07

Publication date

1983-02-28

1977-05-26 Priority claimed from US05/800,674 external-priority patent/US4082627A/en

1977-05-26 Priority claimed from US05/800,673 external-priority patent/US4081458A/en

1978-02-07 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

1983-02-28 Publication of HU180230B publication Critical patent/HU180230B/hu

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
- C07C45/54—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition of compounds containing doubly bound oxygen atoms, e.g. esters
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/65—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
- C07C45/74—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups combined with dehydration
- C—CHEMISTRY; METALLURGY
- C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
- C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
- C25B3/00—Electrolytic production of organic compounds
- C25B3/01—Products
- C25B3/05—Heterocyclic compounds
- C—CHEMISTRY; METALLURGY
- C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
- C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
- C25B3/00—Electrolytic production of organic compounds
- C25B3/01—Products
- C25B3/07—Oxygen containing compounds
- C—CHEMISTRY; METALLURGY
- C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
- C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
- C25B3/00—Electrolytic production of organic compounds
- C25B3/01—Products
- C25B3/09—Nitrogen containing compounds
- C—CHEMISTRY; METALLURGY
- C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
- C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
- C25B3/00—Electrolytic production of organic compounds
- C25B3/01—Products
- C25B3/11—Halogen containing compounds
- C—CHEMISTRY; METALLURGY
- C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
- C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
- C25B3/00—Electrolytic production of organic compounds
- C25B3/20—Processes
- C25B3/25—Reduction

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Health & Medical Sciences (AREA)
Electrochemistry (AREA)
Metallurgy (AREA)
Materials Engineering (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Reproductive Health (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Neurosurgery (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Psychiatry (AREA)
Endocrinology (AREA)
Pregnancy & Childbirth (AREA)
Gynecology & Obstetrics (AREA)
Hospice & Palliative Care (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Pyrane Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

HU78EI777A 1977-05-26 1978-02-07 Process for producing dihydro- and hexahydrobenzopyranoxantenones HU180230B (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US05/800,674 US4082627A (en)	1977-05-26	1977-05-26	Electrolytic reduction of dihydrobenzopyranoxanthenones
US05/800,673 US4081458A (en)	1977-05-26	1977-05-26	Anti-androgen compounds

Publications (1)

Publication Number	Publication Date
HU180230B true HU180230B (en)	1983-02-28

Family

ID=27122240

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HU78EI777A HU180230B (en)	1977-05-26	1978-02-07	Process for producing dihydro- and hexahydrobenzopyranoxantenones

Country Status (25)

Country	Link
JP (1)	JPS53147099A (cs)
AR (1)	AR225133A1 (cs)
AT (1)	AT361920B (cs)
AU (1)	AU515424B2 (cs)
BG (1)	BG30020A3 (cs)
CS (1)	CS214887B2 (cs)
DD (1)	DD134766A5 (cs)
DE (1)	DE2804682A1 (cs)
DK (1)	DK52978A (cs)
ES (1)	ES466756A1 (cs)
FR (1)	FR2392026A1 (cs)
GB (1)	GB1593643A (cs)
GR (1)	GR69964B (cs)
HU (1)	HU180230B (cs)
IE (1)	IE46392B1 (cs)
IL (1)	IL53990A (cs)
IT (1)	IT1092577B (cs)
NL (1)	NL7801392A (cs)
NZ (1)	NZ186387A (cs)
PL (1)	PL110214B1 (cs)
PT (1)	PT67611B (cs)
RO (1)	RO74948A (cs)
SE (1)	SE7801419L (cs)
SU (3)	SU793395A3 (cs)
YU (1)	YU26378A (cs)

1978
- 1978-02-02 AR AR270940A patent/AR225133A1/es active
- 1978-02-02 GB GB4161/78A patent/GB1593643A/en not_active Expired
- 1978-02-03 IE IE232/78A patent/IE46392B1/en unknown
- 1978-02-03 PT PT67611A patent/PT67611B/pt unknown
- 1978-02-03 NZ NZ186387A patent/NZ186387A/xx unknown
- 1978-02-03 DE DE19782804682 patent/DE2804682A1/de not_active Withdrawn
- 1978-02-04 RO RO7893099A patent/RO74948A/ro unknown
- 1978-02-04 GR GR55347A patent/GR69964B/el unknown
- 1978-02-06 DK DK52978A patent/DK52978A/da unknown
- 1978-02-06 AU AU33022/78A patent/AU515424B2/en not_active Expired
- 1978-02-06 FR FR7803250A patent/FR2392026A1/fr active Granted
- 1978-02-06 BG BG038589A patent/BG30020A3/xx unknown
- 1978-02-06 YU YU00263/78A patent/YU26378A/xx unknown
- 1978-02-07 AT AT85178A patent/AT361920B/de not_active IP Right Cessation
- 1978-02-07 IL IL53990A patent/IL53990A/xx unknown
- 1978-02-07 HU HU78EI777A patent/HU180230B/hu unknown
- 1978-02-07 SU SU782574503A patent/SU793395A3/ru active
- 1978-02-07 SE SE7801419A patent/SE7801419L/xx unknown
- 1978-02-07 ES ES466756A patent/ES466756A1/es not_active Expired
- 1978-02-07 IT IT7820058A patent/IT1092577B/it active
- 1978-02-07 CS CS78793A patent/CS214887B2/cs unknown
- 1978-02-07 NL NL7801392A patent/NL7801392A/xx not_active Application Discontinuation
- 1978-02-08 PL PL1978204508A patent/PL110214B1/pl unknown
- 1978-02-08 DD DD78203614A patent/DD134766A5/xx unknown
- 1978-02-10 JP JP1482378A patent/JPS53147099A/ja active Pending
1979
- 1979-03-01 SU SU792734155A patent/SU818485A3/ru active
- 1979-09-06 SU SU792806057A patent/SU927117A3/ru active

Also Published As

Publication number	Publication date
JPS53147099A (en)	1978-12-21
GB1593643A (en)	1981-07-22
SE7801419L (sv)	1978-11-27
YU26378A (en)	1983-02-28
PT67611B (en)	1979-07-16
AU515424B2 (en)	1981-04-02
ES466756A1 (es)	1979-10-01
CS214887B2 (en)	1982-06-25
NZ186387A (en)	1979-06-08
SU793395A3 (ru)	1980-12-30
IT7820058A0 (it)	1978-02-07
FR2392026B1 (cs)	1980-12-26
PL204508A1 (pl)	1979-01-02
RO74948A (ro)	1980-10-30
NL7801392A (nl)	1978-11-28
DD134766A5 (de)	1979-03-21
PL110214B1 (en)	1980-07-31
FR2392026A1 (fr)	1978-12-22
IE780232L (en)	1978-11-26
SU818485A3 (ru)	1981-03-30
GR69964B (cs)	1982-07-22
DK52978A (da)	1978-11-27
AT361920B (de)	1981-04-10
AU3302278A (en)	1979-08-16
IL53990A (en)	1981-09-13
IE46392B1 (en)	1983-06-01
DE2804682A1 (de)	1978-11-30
IT1092577B (it)	1985-07-12
SU927117A3 (ru)	1982-05-07
PT67611A (en)	1978-03-01
AR225133A1 (es)	1982-02-26
BG30020A3 (en)	1981-03-16
ATA85178A (de)	1980-09-15

Publication	Publication Date	Title
Gensler et al.	1960	Compounds Related to Podophyllotoxin. XII. Podophyllotoxone, Picropodophyllone and Dehydropodophyllotoxin1
Biswas et al.	1986	Cassiadinine, a chromone alkaloid and (+)-6-hydroxy-mellein, a dihydroisocoumarin from Cassia siamea
Gramain et al.	1985	A novel and efficient synthesis of the aspidosperma alkaloid ring system: N (a)-benzyldeethylaspidospermidine
Largeron et al.	1995	Novel 1, 4-benzoxazine derivatives of pharmacological interest. Electrochemical and chemical syntheses
Rǎileanu et al.	1971	Nenitzescu synthesis of 5-hydroxyindoles—II: 5, 6, 7-trimethoxyindoles and cyclization of enamino hydroquinones,-quinones and intermediate imino derivatives
Okuda et al.	1959	The Synthesis of 5-Azaindole
Singh et al.	1969	Synthesis of juglone derivatives: Hydroxy, acetyl and ethyl substituents
Pettit et al.	1970	Bufadienolides. 11. Bufalin and resibufogenin
Harris et al.	1968	Condensations of dehydroacetic acid at the 6-methyl position
Glotter et al.	1970	Studies on 1, 4-dioxo-steroids
Hewlins et al.	1981	Synthesis of 8, 9, 10-trimethoxyellipticine
Robinson et al.	1991	Synthesis of 5-azaoxindole
DE1643948A1 (de)	1972-06-08	Verfahren zur Herstellung von Acetylenverbindungen
Castedo et al.	1982	Synthesis of 1‐benzylideneisoquinoline‐3, 4‐diones
Kobayashi et al.	2001	An efficient method for the one-pot construction of the 1 H-naphtho [2, 3-c] pyran-5, 10-dione system
Birch et al.	1979	Studies in relation to biosynthesis. Part 47. Phomazarin. Part 1. The structure of phomazarin, an aza-anthraquinone produced by Pyrenochaeta terrestris Hansen
GB1593643A (en)	1981-07-22	Antiandrogen hydrobenzo-pyranoxanthenones
Raguenet et al.	1996	TOTAL SYNTHESIS OF 8-(1, l-DIMETHYLALLYL). APlGENlN
Katayama et al.	1997	Heterocyclic analogues of quinone methide: preparation and cytotoxicity of 3-Oxo-3H-pyrazolo [1, 5-a] indole derivatives
Comber et al.	1985	The synthesis of hallachrome leucotriacetate (2, 7, 8-triacetoxy-1-methoxy-3-methylanthracene)
Bracher	1992	Polycyclic Aromatic Alkaloids, 8. The Structure of Neocalliactine Acetate—Proof by Total Synthesis
Miller et al.	1964	5α-Androstano [3, 2-b] pyrroles1
Kasturi et al.	1991	One pot synthesis of polycyclic oxygen aromatics. Part III mechanism of formation
Wintersteiner et al.	1951	On The Structure of Jervine: Diacetyl-7-Ketojervine
Kumar et al.	1989	Synthesis of the phenolic derivatives of highly tumorigenic trans-7, 8-dihydroxy-7, 8-dihydrobenzo [a] pyrene