IE46392B1 - Anti-androgen hydrobenzo-pyranoxanthenones - Google Patents

Anti-androgen hydrobenzo-pyranoxanthenones

Info

Publication number: IE46392B1
Authority: IE; Ireland
Prior art keywords: formula; compound; benzopyrano; xanthen; dimethyl
Prior art date: 1977-05-26

Application number

IE232/78A

Other languages

English (en)

Other versions

IE780232L (en

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-05-26

Filing date

1978-02-03

Publication date

1983-06-01

1977-05-26 Priority claimed from US05/800,674 external-priority patent/US4082627A/en

1977-05-26 Priority claimed from US05/800,673 external-priority patent/US4081458A/en

1978-02-03 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

1978-11-26 Publication of IE780232L publication Critical patent/IE780232L/xx

1983-06-01 Publication of IE46392B1 publication Critical patent/IE46392B1/en

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
- C07C45/54—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition of compounds containing doubly bound oxygen atoms, e.g. esters
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/65—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
- C07C45/74—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups combined with dehydration
- C—CHEMISTRY; METALLURGY
- C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
- C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
- C25B3/00—Electrolytic production of organic compounds
- C25B3/01—Products
- C25B3/05—Heterocyclic compounds
- C—CHEMISTRY; METALLURGY
- C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
- C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
- C25B3/00—Electrolytic production of organic compounds
- C25B3/01—Products
- C25B3/07—Oxygen containing compounds
- C—CHEMISTRY; METALLURGY
- C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
- C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
- C25B3/00—Electrolytic production of organic compounds
- C25B3/01—Products
- C25B3/09—Nitrogen containing compounds
- C—CHEMISTRY; METALLURGY
- C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
- C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
- C25B3/00—Electrolytic production of organic compounds
- C25B3/01—Products
- C25B3/11—Halogen containing compounds
- C—CHEMISTRY; METALLURGY
- C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
- C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
- C25B3/00—Electrolytic production of organic compounds
- C25B3/20—Processes
- C25B3/25—Reduction

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Health & Medical Sciences (AREA)
Electrochemistry (AREA)
Metallurgy (AREA)
Materials Engineering (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Reproductive Health (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Neurosurgery (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Psychiatry (AREA)
Endocrinology (AREA)
Pregnancy & Childbirth (AREA)
Gynecology & Obstetrics (AREA)
Hospice & Palliative Care (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Pyrane Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

IE232/78A 1977-05-26 1978-02-03 Anti-androgen hydrobenzo-pyranoxanthenones IE46392B1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US05/800,674 US4082627A (en)	1977-05-26	1977-05-26	Electrolytic reduction of dihydrobenzopyranoxanthenones
US05/800,673 US4081458A (en)	1977-05-26	1977-05-26	Anti-androgen compounds

Publications (2)

Publication Number	Publication Date
IE780232L IE780232L (en)	1978-11-26
IE46392B1 true IE46392B1 (en)	1983-06-01

Family

ID=27122240

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IE232/78A IE46392B1 (en)	1977-05-26	1978-02-03	Anti-androgen hydrobenzo-pyranoxanthenones

Country Status (25)

Country	Link
JP (1)	JPS53147099A (cs)
AR (1)	AR225133A1 (cs)
AT (1)	AT361920B (cs)
AU (1)	AU515424B2 (cs)
BG (1)	BG30020A3 (cs)
CS (1)	CS214887B2 (cs)
DD (1)	DD134766A5 (cs)
DE (1)	DE2804682A1 (cs)
DK (1)	DK52978A (cs)
ES (1)	ES466756A1 (cs)
FR (1)	FR2392026A1 (cs)
GB (1)	GB1593643A (cs)
GR (1)	GR69964B (cs)
HU (1)	HU180230B (cs)
IE (1)	IE46392B1 (cs)
IL (1)	IL53990A (cs)
IT (1)	IT1092577B (cs)
NL (1)	NL7801392A (cs)
NZ (1)	NZ186387A (cs)
PL (1)	PL110214B1 (cs)
PT (1)	PT67611B (cs)
RO (1)	RO74948A (cs)
SE (1)	SE7801419L (cs)
SU (3)	SU793395A3 (cs)
YU (1)	YU26378A (cs)

1978
- 1978-02-02 AR AR270940A patent/AR225133A1/es active
- 1978-02-02 GB GB4161/78A patent/GB1593643A/en not_active Expired
- 1978-02-03 IE IE232/78A patent/IE46392B1/en unknown
- 1978-02-03 PT PT67611A patent/PT67611B/pt unknown
- 1978-02-03 NZ NZ186387A patent/NZ186387A/xx unknown
- 1978-02-03 DE DE19782804682 patent/DE2804682A1/de not_active Withdrawn
- 1978-02-04 RO RO7893099A patent/RO74948A/ro unknown
- 1978-02-04 GR GR55347A patent/GR69964B/el unknown
- 1978-02-06 DK DK52978A patent/DK52978A/da unknown
- 1978-02-06 AU AU33022/78A patent/AU515424B2/en not_active Expired
- 1978-02-06 FR FR7803250A patent/FR2392026A1/fr active Granted
- 1978-02-06 BG BG038589A patent/BG30020A3/xx unknown
- 1978-02-06 YU YU00263/78A patent/YU26378A/xx unknown
- 1978-02-07 AT AT85178A patent/AT361920B/de not_active IP Right Cessation
- 1978-02-07 IL IL53990A patent/IL53990A/xx unknown
- 1978-02-07 HU HU78EI777A patent/HU180230B/hu unknown
- 1978-02-07 SU SU782574503A patent/SU793395A3/ru active
- 1978-02-07 SE SE7801419A patent/SE7801419L/xx unknown
- 1978-02-07 ES ES466756A patent/ES466756A1/es not_active Expired
- 1978-02-07 IT IT7820058A patent/IT1092577B/it active
- 1978-02-07 CS CS78793A patent/CS214887B2/cs unknown
- 1978-02-07 NL NL7801392A patent/NL7801392A/xx not_active Application Discontinuation
- 1978-02-08 PL PL1978204508A patent/PL110214B1/pl unknown
- 1978-02-08 DD DD78203614A patent/DD134766A5/xx unknown
- 1978-02-10 JP JP1482378A patent/JPS53147099A/ja active Pending
1979
- 1979-03-01 SU SU792734155A patent/SU818485A3/ru active
- 1979-09-06 SU SU792806057A patent/SU927117A3/ru active

Also Published As

Publication number	Publication date
JPS53147099A (en)	1978-12-21
GB1593643A (en)	1981-07-22
SE7801419L (sv)	1978-11-27
YU26378A (en)	1983-02-28
PT67611B (en)	1979-07-16
AU515424B2 (en)	1981-04-02
ES466756A1 (es)	1979-10-01
CS214887B2 (en)	1982-06-25
NZ186387A (en)	1979-06-08
SU793395A3 (ru)	1980-12-30
IT7820058A0 (it)	1978-02-07
FR2392026B1 (cs)	1980-12-26
PL204508A1 (pl)	1979-01-02
RO74948A (ro)	1980-10-30
NL7801392A (nl)	1978-11-28
DD134766A5 (de)	1979-03-21
PL110214B1 (en)	1980-07-31
FR2392026A1 (fr)	1978-12-22
IE780232L (en)	1978-11-26
SU818485A3 (ru)	1981-03-30
GR69964B (cs)	1982-07-22
DK52978A (da)	1978-11-27
AT361920B (de)	1981-04-10
AU3302278A (en)	1979-08-16
IL53990A (en)	1981-09-13
DE2804682A1 (de)	1978-11-30
IT1092577B (it)	1985-07-12
SU927117A3 (ru)	1982-05-07
PT67611A (en)	1978-03-01
AR225133A1 (es)	1982-02-26
HU180230B (en)	1983-02-28
BG30020A3 (en)	1981-03-16
ATA85178A (de)	1980-09-15

Publication	Publication Date	Title
Stille et al.	1964	Oxirene. An intermediate in the peroxyacid oxidation of acetylenes
Suzuki et al.	1978	Total synthesis of anthracyclinones via intramolecular base-catalyzed cyclizations
WOLINSKY	1961	Ring Enlargement Produced by the Alkaline Fusion of ι-Bromocamphene
Ganguli et al.	1984	Structural studies of the mycotoxin verrucosidin
Shimizu	1972	Characterization of an acid hydrolysis product of starfish toxins as a 5. alpha.-pregnane derivative
Capraro et al.	1979	Simple conversion of colchicine into demecolcine
YAMAKAWA et al.	1977	Studies on Terpenoids and Related Alicyclic Compounds. X. Total Synthesis of Sesquiterpenoid,(±)-Ligularone
Bobbitt et al.	1964	Synthesis of Isoquinolines. I. 1 Copyrine and Isoquinoline Systems Derived from 3-Cyano-4-methylpyridine2, 3
Fieser et al.	1953	Permanganate oxidation of ergosterol
Becker	1969	Quinone dehydrogenation. III. Oxidation of 2, 4-di-tert-butylphenol
Edwards et al.	1964	Steroids. CCLXIII. 1 The Synthesis of 2-Formyl-Δ1-and-Δ1, 4-3-keto Steroids2
US4081458A (en)	1978-03-28	Anti-androgen compounds
Paryzek	1979	Tetracyclic triterpenes. Part 2. A synthetic approach to cucurbitacins
Bernstein et al.	1953	Steroidal Cyclic Ketals. VIII. 1▵ 4, 9 (11)-Pregnadi ene-17α, 21-diol-3, 20-dione
DE1643948A1 (de)	1972-06-08	Verfahren zur Herstellung von Acetylenverbindungen
Miki et al.	1965	An Improved Synthesis of Estrogens.
Ireland et al.	1969	Experiments directed toward the total synthesis of terpenes. XIII. Construction of the lactone ring of rosenonolactone
Chorvat et al.	1976	Synthesis of 2-azaestratrienes
GB1593643A (en)	1981-07-22	Antiandrogen hydrobenzo-pyranoxanthenones
US3787394A (en)	1974-01-22	19-nor-7alpha-methyl or 19-nor-20-spirox-4,14-dien-3-one and 18-methyl derivatives thereof
CS214888B2 (cs)	1982-06-25	Způsob přípravy nových liexahydrobenzopyraiioxanthenonů
Sicherer‐Roetman et al.	1985	Investigations into the total synthesis of momilactones. Stereoselective preparation of (±)‐4, 4‐dinor‐9βH‐pimara‐7, 19‐diene
Cooper et al.	1961	Preparation of Trimethylsilyl-Substituted Dihydric Phenols and Trimethylsilybenzoquinone
Miller et al.	1964	5α-Androstano [3, 2-b] pyrroles1
Pellegatat et al.	1999	A new reduction of the enone system of 18b-glycyrrhetic acid