HU199168B - Process for producing new macrolide antibioticum and pharmaceutical compositions containing them - Google Patents

Process for producing new macrolide antibioticum and pharmaceutical compositions containing them Download PDF

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Publication number
HU199168B
HU199168B HU873778A HU377887A HU199168B HU 199168 B HU199168 B HU 199168B HU 873778 A HU873778 A HU 873778A HU 377887 A HU377887 A HU 377887A HU 199168 B HU199168 B HU 199168B
Authority
HU
Hungary
Prior art keywords
swalpamycin
streptomyces
formula
mycelium
filtrate
Prior art date
Application number
HU873778A
Other languages
English (en)
Hungarian (hu)
Other versions
HUT46075A (en
Inventor
Christopher M Franco
Goukanapalli
Bimal N Ganguli
Herbert Kogler
Julia Gandhi
Sugata Chatterjee
Richard H Rupp
Hans-Wolfram Fehlhaber
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of HUT46075A publication Critical patent/HUT46075A/hu
Publication of HU199168B publication Critical patent/HU199168B/hu

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
HU873778A 1986-08-27 1987-08-27 Process for producing new macrolide antibioticum and pharmaceutical compositions containing them HU199168B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3629063 1986-08-27

Publications (2)

Publication Number Publication Date
HUT46075A HUT46075A (en) 1988-09-28
HU199168B true HU199168B (en) 1990-01-29

Family

ID=6308254

Family Applications (1)

Application Number Title Priority Date Filing Date
HU873778A HU199168B (en) 1986-08-27 1987-08-27 Process for producing new macrolide antibioticum and pharmaceutical compositions containing them

Country Status (14)

Country Link
US (1) US4988677A (2)
EP (1) EP0257615B1 (2)
JP (1) JPS6368596A (2)
KR (1) KR880003010A (2)
AT (2) ATE70065T1 (2)
AU (1) AU601474B2 (2)
DE (1) DE3774963D1 (2)
DK (1) DK445987A (2)
ES (1) ES2038634T3 (2)
GR (1) GR3003852T3 (2)
HU (1) HU199168B (2)
IL (1) IL83626A (2)
PT (1) PT85590B (2)
ZA (1) ZA876350B (2)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5486630A (en) * 1994-09-14 1996-01-23 Cheil Foods & Chemicals Inc. Legionella specific antibiotic
FR2870853A1 (fr) * 2004-05-26 2005-12-02 Toulouse Inst Nat Polytech Nouvelle souche saccharothrix et ses antibiotiques derives, notamment mutactimycines et aldgamycines

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62103098A (ja) * 1985-05-13 1987-05-13 Microbial Chem Res Found タイロシン誘導体
US4835141A (en) * 1986-12-05 1989-05-30 Pfizer Inc. Neutral macrolide antibiotics from Streptomyces

Also Published As

Publication number Publication date
ZA876350B (en) 1988-02-29
ES2038634T3 (es) 1993-08-01
AT389319B (de) 1989-11-27
US4988677A (en) 1991-01-29
EP0257615B1 (de) 1991-12-04
IL83626A (en) 1993-07-08
KR880003010A (ko) 1988-05-13
AU601474B2 (en) 1990-09-13
DE3774963D1 (de) 1992-01-16
ATE70065T1 (de) 1991-12-15
AU7743287A (en) 1988-03-03
IL83626A0 (en) 1988-01-31
HUT46075A (en) 1988-09-28
GR3003852T3 (2) 1993-03-16
EP0257615A3 (en) 1988-11-09
DK445987D0 (da) 1987-08-26
DK445987A (da) 1988-02-28
PT85590B (pt) 1990-05-31
ATA260687A (de) 1989-04-15
EP0257615A2 (de) 1988-03-02
JPS6368596A (ja) 1988-03-28
PT85590A (de) 1987-09-01

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Legal Events

Date Code Title Description
HU90 Patent valid on 900628
HMM4 Cancellation of final prot. due to non-payment of fee