HU204062B - Process for producing (geminal heterocyclo-bis/aminomethyl/-n,n')-platinum complexes and pharmaceutical compositions comprising same - Google Patents

Process for producing (geminal heterocyclo-bis/aminomethyl/-n,n')-platinum complexes and pharmaceutical compositions comprising same Download PDF

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Publication number
HU204062B
HU204062B HU87308A HU30887A HU204062B HU 204062 B HU204062 B HU 204062B HU 87308 A HU87308 A HU 87308A HU 30887 A HU30887 A HU 30887A HU 204062 B HU204062 B HU 204062B
Authority
HU
Hungary
Prior art keywords
bis
aminomethyl
platinum
oxetane
tetrahydro
Prior art date
Application number
HU87308A
Other languages
English (en)
Hungarian (hu)
Other versions
HUT44573A (en
Inventor
Joseph John Hlavka
Panayota Bitha
Ralph Grassing Child
Yang-I Lin
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25241319&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HU204062(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of HUT44573A publication Critical patent/HUT44573A/hu
Publication of HU204062B publication Critical patent/HU204062B/hu

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F17/00—Metallocenes
    • C07F17/02—Metallocenes of metals of Groups 8, 9 or 10 of the Periodic Table
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/02—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Furan Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrane Compounds (AREA)
HU87308A 1986-01-31 1987-01-30 Process for producing (geminal heterocyclo-bis/aminomethyl/-n,n')-platinum complexes and pharmaceutical compositions comprising same HU204062B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/824,404 US4880790A (en) 1986-01-31 1986-01-31 (Gem-heterocyclodimethanamine-N,N')platinum complexes

Publications (2)

Publication Number Publication Date
HUT44573A HUT44573A (en) 1988-03-28
HU204062B true HU204062B (en) 1991-11-28

Family

ID=25241319

Family Applications (1)

Application Number Title Priority Date Filing Date
HU87308A HU204062B (en) 1986-01-31 1987-01-30 Process for producing (geminal heterocyclo-bis/aminomethyl/-n,n')-platinum complexes and pharmaceutical compositions comprising same

Country Status (18)

Country Link
US (2) US4880790A (2)
EP (1) EP0232784B1 (2)
JP (1) JPS62246564A (2)
KR (1) KR900004404B1 (2)
AT (1) ATE82980T1 (2)
AU (1) AU597932B2 (2)
CA (1) CA1297113C (2)
DE (1) DE3782831T2 (2)
DK (1) DK50587A (2)
ES (1) ES2052499T3 (2)
FI (1) FI84271C (2)
GR (1) GR3006594T3 (2)
HU (1) HU204062B (2)
IE (2) IE870244L (2)
NO (1) NO870398L (2)
NZ (1) NZ219093A (2)
PH (1) PH24310A (2)
ZA (1) ZA87713B (2)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4870070A (en) * 1987-08-10 1989-09-26 American Cyanamid Company Water soluble platinum complexes of novel malonate derivatives
JP4899385B2 (ja) * 2005-09-06 2012-03-21 宇部興産株式会社 ３−アミノメチルオキセタン化合物の製法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2195426B1 (2) * 1972-08-09 1975-10-17 Lipha
NL7807334A (nl) * 1978-07-06 1980-01-08 Tno Platina-diaminecomplexen, werkwijze voor het bereiden daarvan, werkwijze voor het bereiden van een genees- middel met toepassing van een dergelijk platina-dia- minecomplex voor de behandeling van kanker, alsmede al- dus verkregen gevormd geneesmiddel.
NL8204067A (nl) * 1982-10-21 1984-05-16 Tno Platina-diaminecomplexen, werkwijze voor het bereiden daarvan, werkwijze voor het bereiden van een geneesmiddel met toepassing van een dergelijk platinadiaminecomplex voor de behandeling van kanker, alsmede aldus verkregen gevormd geneesmiddel.
US4500465A (en) * 1982-06-28 1985-02-19 Engelhard Corporation Solubilized platinum (II) complexes
DE3432320A1 (de) * 1984-09-03 1986-03-13 Behringwerke Ag, 3550 Marburg Cis-platin-komplexe mit einem pentaerythritderivat als liganden, verfahren zu ihrer herstellung und diese verbindungen enthaltendes pharmazeutisches mittel
JPS63112591A (ja) * 1986-10-29 1988-05-17 Nippon Kayaku Co Ltd 新規白金錯体
JPH112591A (ja) * 1997-06-11 1999-01-06 Taihei Kogyo Co Ltd サンプル片採取装置におけるサンプル切断位置の制御方法

Also Published As

Publication number Publication date
EP0232784A3 (en) 1989-05-31
US4880790A (en) 1989-11-14
ZA87713B (en) 1987-09-30
HUT44573A (en) 1988-03-28
KR900004404B1 (ko) 1990-06-25
IE870244L (en) 1987-07-31
FI870416A0 (fi) 1987-01-30
DE3782831T2 (de) 1993-05-06
CA1297113C (en) 1992-03-10
AU6816787A (en) 1987-08-06
PH24310A (en) 1990-05-29
DK50587A (da) 1987-08-01
NO870398D0 (no) 1987-01-30
GR3006594T3 (2) 1993-06-30
EP0232784A2 (en) 1987-08-19
FI84271B (fi) 1991-07-31
NZ219093A (en) 1990-03-27
ES2052499T3 (es) 1994-07-16
ATE82980T1 (de) 1992-12-15
AU597932B2 (en) 1990-06-14
DK50587D0 (da) 1987-01-30
IE870245L (en) 1987-07-31
FI870416A7 (fi) 1987-08-01
KR870007191A (ko) 1987-08-17
US6281365B1 (en) 2001-08-28
JPS62246564A (ja) 1987-10-27
FI84271C (fi) 1991-11-11
NO870398L (no) 1987-08-03
DE3782831D1 (de) 1993-01-14
IE59743B1 (en) 1994-03-23
EP0232784B1 (en) 1992-12-02

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Legal Events

Date Code Title Description
HMM4 Cancellation of final prot. due to non-payment of fee