HU211282A9 - Benzoxazin derivatives, pharmaceutical compositions containing them and process for their production - Google Patents

Benzoxazin derivatives, pharmaceutical compositions containing them and process for their production Download PDF

Info

Publication number
HU211282A9
HU211282A9 HU95P/P00620P HU9500620P HU211282A9 HU 211282 A9 HU211282 A9 HU 211282A9 HU 9500620 P HU9500620 P HU 9500620P HU 211282 A9 HU211282 A9 HU 211282A9
Authority
HU
Hungary
Prior art keywords
group
lower alkyl
formula
halogen
hydroxy
Prior art date
Application number
HU95P/P00620P
Other languages
English (en)
Hungarian (hu)
Inventor
Isao Yanagisawa
Toru Yoden
Yuzo Matsumoto
Ryuji Tsuzuki
Akira Matsuhisa
Kazuhisa Takayama
Wataru Uchida
Masaharu Asano
Original Assignee
Yamanouchi Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamanouchi Pharma Co Ltd filed Critical Yamanouchi Pharma Co Ltd
Publication of HU211282A9 publication Critical patent/HU211282A9/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HU95P/P00620P 1989-11-08 1995-06-30 Benzoxazin derivatives, pharmaceutical compositions containing them and process for their production HU211282A9 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP29072789 1989-11-08
JP31592689 1989-12-05
JP34293789 1989-12-28
JP20854890 1990-08-06

Publications (1)

Publication Number Publication Date
HU211282A9 true HU211282A9 (en) 1995-11-28

Family

ID=27476415

Family Applications (1)

Application Number Title Priority Date Filing Date
HU95P/P00620P HU211282A9 (en) 1989-11-08 1995-06-30 Benzoxazin derivatives, pharmaceutical compositions containing them and process for their production

Country Status (11)

Country Link
EP (1) EP0432893A3 (2)
JP (1) JPH0774208B2 (2)
KR (1) KR950007757B1 (2)
AU (1) AU641953B2 (2)
FI (1) FI905510A7 (2)
HU (1) HU211282A9 (2)
IE (1) IE904013A1 (2)
NO (1) NO904839L (2)
PH (1) PH30439A (2)
PT (1) PT95798A (2)
TW (1) TW224941B (2)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ222843A (en) * 1986-12-22 1989-10-27 Ortho Pharma Corp Benzoxazinyl- and benzothiazinyl-tetrahydropyridazinones and intermediates, and medicaments
CN1060467A (zh) * 1990-09-25 1992-04-22 武田药品工业株式会社 1，3-苯并嗪衍生物、其生产方法和用途
CA2061179A1 (en) * 1991-02-18 1992-08-19 Ryuji Tsuzuki Oxzazinobenzazole compounds
US5262419A (en) * 1992-06-11 1993-11-16 E. R. Squibb & Sons, Inc. Method for the prophylaxis and/or treatment of ulcerative gastrointestinal conditions using a potassium channel activator
JPH06220029A (ja) * 1992-12-03 1994-08-09 Ss Pharmaceut Co Ltd １，４−ベンズオキサジン誘導体
GB9225860D0 (en) * 1992-12-11 1993-02-03 Smithkline Beecham Plc Novel treatment
GB9225859D0 (en) * 1992-12-11 1993-02-03 Smithkline Beecham Plc Novel treatment
WO1994018195A1 (fr) * 1993-02-05 1994-08-18 Yamanouchi Pharmaceutical Co., Ltd. Nouveau derive de benzoxazine, medicament le contenant, et son intermediaire
GB9309716D0 (en) * 1993-05-12 1993-06-23 Zeneca Ltd Heterocyclic derivatives
CN1109880A (zh) * 1994-02-03 1995-10-11 合成实验室公司 3-(2-氨基乙基)-4-[3-(三氟甲基)苯甲酰基]-3，4-二氢-2h-1，4-苯并噁嗪衍生物、制备及其应用
CN1065529C (zh) * 1994-06-09 2001-05-09 爱斯制药株式会社 4－喹啉酮衍生物及其盐
EP1004316B1 (en) * 1997-08-08 2005-11-02 Chugai Seiyaku Kabushiki Kaisha Therapeutics for diabetic complications
KR100466809B1 (ko) * 1998-06-30 2006-01-27 씨제이 주식회사 즉석닭튀김식품의제조방법
AU5444499A (en) * 1998-09-01 2000-03-21 Nissan Chemical Industries Ltd. Benzoxazine derivatives
US6455554B1 (en) 1999-06-07 2002-09-24 Targacept, Inc. Oxopyridinyl pharmaceutical compositions and methods for use
WO2002072049A1 (en) * 2001-02-27 2002-09-19 Yamanouchi Pharmaceutical Co., Ltd. Medicinal compositions for stimulating hair growth
JP2004528335A (ja) * 2001-04-23 2004-09-16 アストラゼネカ アクチボラグ 血管新生の治療に使用のベンゾオキサジノン誘導体
TWI329105B (en) 2002-02-01 2010-08-21 Rigel Pharmaceuticals Inc 2,4-pyrimidinediamine compounds and their uses
ES2445208T3 (es) 2002-07-29 2014-02-28 Rigel Pharmaceuticals, Inc. Compuestos de 2,4-pirimidindiamina para uso en métodos para tratar o prevenir enfermedades autoinmunitarias
BRPI0413018B8 (pt) 2003-07-30 2021-05-25 Rigel Pharmaceuticals Inc composto, e, uso de um composto
KR100823805B1 (ko) * 2004-05-05 2008-04-21 에프. 호프만-라 로슈 아게 5-ｈｔ6 수용체, 5-ｈｔ2ａ 수용체 또는 둘다를 조절하기에유용한 아릴설포닐 벤조다이옥산
US7378415B2 (en) 2004-09-30 2008-05-27 Roche Palo Alto Llc Benzoxazine and quinoxaline derivatives and uses thereof
AU2005291541B2 (en) * 2004-09-30 2011-03-10 F. Hoffmann-La Roche Ag Benzoxazine and quinoxaline derivatives and uses
GB0428526D0 (en) 2004-12-30 2005-02-09 Novartis Ag Organic compounds
DE602006010979D1 (de) 2005-01-19 2010-01-21 Rigel Pharmaceuticals Inc Prodrugs aus 2,4-pyrimidindiamin-verbindungen und ihre verwendungen
JP5306821B2 (ja) 2005-12-30 2013-10-02 ノバルティス アーゲー レニン阻害剤としての３，５−置換ピペリジン化合物
EP1985297A1 (en) * 2006-01-27 2008-10-29 Japan Tobacco, Inc. Carboxylic acid compound and use thereof
TWI385161B (zh) 2006-02-02 2013-02-11 Mitsubishi Tanabe Pharma Corp 含氮雜雙環化合物
ES2439948T3 (es) 2006-02-17 2014-01-27 Rigel Pharmaceuticals, Inc. Compuestos de 2,4-pirimidindiamina para el tratamiento o la prevención de enfermedades autoinmunitarias
JP5903499B2 (ja) 2011-12-22 2016-04-13 ノバルティス アーゲー ジヒドロ−ベンゾ−オキサジンおよびジヒドロ−ピリド−オキサジン誘導体
CN115181264B (zh) * 2022-07-20 2023-05-23 中国航空工业集团公司济南特种结构研究所 一种苯并噁嗪中间体及其制备方法和聚苯并噁嗪树脂制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1595863C3 (de) * 1966-08-11 1978-03-02 Knoll Ag, 6700 Ludwigshafen 4-Piperidinoacetyl-3,4-dihydro-(2H)-l,4-benioxazin und Verfahren zu dessen Herstellung
GB1173942A (en) * 1967-06-06 1969-12-10 Bellon Labor Sa Roger New 2,3-Dihydro-1,4-Benzoxazines
EP0076075B1 (en) * 1981-09-25 1986-11-20 Beecham Group Plc Pharmaceutically active benzopyran compounds
JPS61215381A (ja) * 1985-03-22 1986-09-25 Ube Ind Ltd ベンゾオキサジン誘導体および除草剤
NZ222843A (en) * 1986-12-22 1989-10-27 Ortho Pharma Corp Benzoxazinyl- and benzothiazinyl-tetrahydropyridazinones and intermediates, and medicaments
JPS63270678A (ja) * 1987-04-30 1988-11-08 Mitsui Petrochem Ind Ltd 新規含窒素化合物
EP0290863A3 (en) * 1987-05-09 1989-03-15 Nihon Tokushu Noyaku Seizo K.K. Benzoxazine derivative, process and intermediates for its preparation and its use as herbicide
EP0298542B1 (en) * 1987-07-07 1990-12-12 Shell Internationale Researchmaatschappij B.V. Process for preparing thiophene derivatives
GB8800199D0 (en) * 1988-01-06 1988-02-10 Beecham Group Plc Pharmaceutical preparation

Also Published As

Publication number Publication date
JPH04178375A (ja) 1992-06-25
FI905510A0 (fi) 1990-11-07
EP0432893A2 (en) 1991-06-19
KR910009682A (ko) 1991-06-28
NO904839L (no) 1991-05-10
NO904839D0 (no) 1990-11-07
AU641953B2 (en) 1993-10-07
JPH0774208B2 (ja) 1995-08-09
PT95798A (pt) 1991-09-13
TW224941B (2) 1994-06-11
KR950007757B1 (ko) 1995-07-14
PH30439A (en) 1997-05-09
IE904013A1 (en) 1991-05-08
EP0432893A3 (en) 1991-07-10
AU6594790A (en) 1991-06-06
FI905510A7 (fi) 1991-05-09

Similar Documents

Publication Publication Date Title
HU211282A9 (en) Benzoxazin derivatives, pharmaceutical compositions containing them and process for their production
US5756496A (en) Amide derivatives having 5HT1D-antagonist activity
JP5305914B2 (ja) オキサゾール化合物及び医薬組成物
JP2602635B2 (ja) オキサゾリジン−２−オン誘導体
JPH04243877A (ja) チオキソ複素環式化合物、その製造方法、ロイコトリエンが介在する疾患および症状の治療において使用するためのこの化合物を有する医薬品
JPH09501439A (ja) ニューロキニンアンタゴニストとして有用な複素環
US5710152A (en) Benzoazine derivative or salt thereof and pharmaceutical compostion comprising the same
FR2551439A1 (fr) Agents antidepression a base de 1,2,4-triazol-3-one
EP0433149B1 (fr) Antagonistes de la sérotonine, leur préparation et les médicaments les contenant
US7141562B2 (en) Substituted benzoxazinones and uses thereof
SE465928B (sv) 1,2,4-triazolonfoereningar med antidepressiv aktivitet, foerfarande foer framstaellning av dessa och en farmaceutisk komposition
US5182296A (en) Naphthyloxazolidone derivatives
JPH0641455B2 (ja) ピリダジノン誘導体
KR100691090B1 (ko) 퀴놀리논/벤즈옥사지논 유도체 및 이들의 용도
JP4986927B2 (ja) 医薬
JP2840288B2 (ja) 置換１―（１ｈ―イミダゾール―４―イル）アルキル―ベンズアミド
US5179111A (en) Imidazole derivatives
US7378415B2 (en) Benzoxazine and quinoxaline derivatives and uses thereof
US5420126A (en) 3,4-dihydro-2H-1,4-benzoxazine derivatives and pharmaceutical compositions containing the same
HU199124B (en) Process for producing benzazepine sulfonamides and antiarrhythmic agents comprising these compounds
EP0639184A1 (en) New quinazolines as inhibitors of hiv reverse transcriptase
JP2001519413A (ja) 良性の前立腺過形成の治療に有用な複素環化合物およびそれらの中間体
US5086052A (en) Substituted 1,4,5,6-tetrahydro-2H-pyridazin-3-one and -3-thione compounds having lipoxygenase inhibitory activity
US5440036A (en) 1,4-benzoxazine derivatives
JPH01156966A (ja) リポキシゲナーゼ抑制作用を有するピリダジノン、トリアジノンおよびオキサピリダジノン化合物