HU220189B - Gyengített légzési syncytialis vírus vakcinakészítmények - Google Patents
Gyengített légzési syncytialis vírus vakcinakészítmények Download PDFInfo
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- HU220189B HU220189B HU9403023A HU9403023A HU220189B HU 220189 B HU220189 B HU 220189B HU 9403023 A HU9403023 A HU 9403023A HU 9403023 A HU9403023 A HU 9403023A HU 220189 B HU220189 B HU 220189B
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- Prior art keywords
- virus
- rsv
- attenuated
- vaccine composition
- cpts
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- Public Health (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87274692A | 1992-04-21 | 1992-04-21 | |
| US3994593A | 1993-04-09 | 1993-04-09 | |
| PCT/US1993/003670 WO1993021310A1 (en) | 1992-04-21 | 1993-04-20 | Attenuated respiratory syncytial virus vaccine compositions |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| HU9403023D0 HU9403023D0 (en) | 1994-12-28 |
| HUT69992A HUT69992A (en) | 1995-09-28 |
| HU220189B true HU220189B (hu) | 2001-11-28 |
Family
ID=26716607
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU9403023A HU220189B (hu) | 1992-04-21 | 1993-04-20 | Gyengített légzési syncytialis vírus vakcinakészítmények |
Country Status (18)
| Country | Link |
|---|---|
| US (3) | US5922326A (de) |
| EP (1) | EP0640128B1 (de) |
| JP (1) | JP3883202B2 (de) |
| KR (1) | KR100257171B1 (de) |
| AT (1) | ATE181359T1 (de) |
| AU (1) | AU683840B2 (de) |
| CA (1) | CA2118509C (de) |
| DE (1) | DE69325370T2 (de) |
| DK (1) | DK0640128T3 (de) |
| ES (1) | ES2132233T3 (de) |
| GR (1) | GR3031208T3 (de) |
| HU (1) | HU220189B (de) |
| IL (1) | IL105456A (de) |
| MX (1) | MX9302278A (de) |
| NZ (1) | NZ252857A (de) |
| RU (1) | RU2139729C1 (de) |
| UA (1) | UA41315C2 (de) |
| WO (1) | WO1993021310A1 (de) |
Families Citing this family (59)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9200117D0 (en) | 1992-01-06 | 1992-02-26 | Connaught Lab | Production of recombinant chimeric proteins for vaccine use |
| TW275632B (de) * | 1992-04-21 | 1996-05-11 | American Cyanamid Co | |
| RU2142817C1 (ru) | 1993-08-06 | 1999-12-20 | Коннот Лабораториз Лимитед | Инактивированные вакцины респираторно-синцитиального вируса |
| US7223410B1 (en) | 1994-08-05 | 2007-05-29 | Sanofi Pasteur Limited | Inactivated respiratory syncytial viral vaccines |
| US5789229A (en) * | 1994-09-30 | 1998-08-04 | Uab Research Foundation | Stranded RNA virus particles |
| US5716821A (en) * | 1994-09-30 | 1998-02-10 | Uab Research Foundation | Prevention and treatment of respiratory tract disease |
| US6083925A (en) | 1995-06-07 | 2000-07-04 | Connaught Laboratories Limited | Nucleic acid respiratory syncytial virus vaccines |
| US6019980A (en) * | 1995-06-07 | 2000-02-01 | Connaught Laboratories Limited | Nucleic acid respiratory syncytial virus vaccines |
| US7485440B2 (en) | 1995-09-27 | 2009-02-03 | The United States Of America As Represented By The Department Of Health And Human Services | Production of attenuated respiratory syncytial virus vaccines involving modification of M2 ORF2 |
| US6689367B1 (en) | 1995-09-27 | 2004-02-10 | The United States Of America As Represented By The Department Of Health And Human Services | Production of attenuated chimeric respiratory syncytial virus vaccines from cloned nucleotide sequences |
| US20050287540A1 (en) * | 1995-09-27 | 2005-12-29 | Murphy Brian R | Production of attenuated negative stranded RNA virus vaccines from cloned nucleotide sequences |
| US7846455B2 (en) | 1996-07-15 | 2010-12-07 | The United States Of America As Represented By The Department Of Health And Human Services | Attenuated chimeric respiratory syncytial virus |
| US6264957B1 (en) | 1995-09-27 | 2001-07-24 | The United States Of America As Represented By The Department Of Health And Human Services | Product of infectious respiratory syncytial virus from cloned nucleotide sequences |
| WO1997038138A1 (en) * | 1996-04-04 | 1997-10-16 | The Regents Of The University Of Michigan | Attenuated respiratory syncytial virus |
| US6077514A (en) * | 1996-04-04 | 2000-06-20 | The Regents Of The University Of Michigan | Attenuated respiratory syncytial virus |
| DE69720024D1 (de) * | 1996-07-12 | 2003-04-24 | Aventis Pasteur | Immunisierungsverfahren in zwei schritten gegen pyramyxoviridae-viren unter verwendung abgeschwächter viraler stämme und preparation von proteinuntereinheiten |
| WO1998002530A1 (en) | 1996-07-15 | 1998-01-22 | The Government Of The United States Of America, As Represented By The Department Of Health And Human Services | Production of attenuated respiratory syncytial virus vaccines from cloned nucleotide sequences |
| US6699476B1 (en) | 1996-07-15 | 2004-03-02 | Peter L. Collins | Production of recombinant respiratory syncytial viruses expressing immune modulatory molecules |
| CA2265554A1 (en) * | 1996-09-27 | 1998-04-02 | American Cyanamid Company | 3' genomic promoter region and polymerase gene mutations responsible for attenuation in viruses of the order designated mononegavirales |
| US7632508B2 (en) | 1997-05-23 | 2009-12-15 | The United States Of America | Attenuated human-bovine chimeric parainfluenza virus (PIV) vaccines |
| US20030082209A1 (en) | 2000-07-05 | 2003-05-01 | Skiadopoulos Mario H. | Attenuated human-bovine chimeric parainfluenza virus (PIV) vaccines |
| US6410023B1 (en) | 1997-05-23 | 2002-06-25 | United States Of America | Recombinant parainfluenza virus vaccines attenuated by deletion or ablation of a non-essential gene |
| US7951383B2 (en) | 1997-05-23 | 2011-05-31 | The United States Of America As Represented By The Department Of Health And Human Services | Attenuated parainfluenza virus (PIV) vaccines |
| US7201907B1 (en) | 1997-05-23 | 2007-04-10 | The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Attenuated human-bovine chimeric parainfluenza virus(PIV) vaccines |
| FR2764903A1 (fr) * | 1997-06-23 | 1998-12-24 | Pasteur Institut | Detection des infections par des paramyxovirus (virus respiratoire syncitial et virus parainfluenza) utilisant des polynucleotides codant de la proteine l |
| US7662397B2 (en) | 1997-07-15 | 2010-02-16 | The United States Of America As Represented By The Department Of Health And Human Services | Respiratory syncytial virus vaccines expressing protective antigens from promoter-proximal genes |
| US20040005542A1 (en) | 2001-06-22 | 2004-01-08 | Krempl Christine D | Respiratory syncytial virus vaccines expressing protective antigens from promotor- proximal genes |
| US6579528B1 (en) | 1998-08-13 | 2003-06-17 | The University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Cold-adapted equine influenza viruses |
| US6482414B1 (en) | 1998-08-13 | 2002-11-19 | The University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Cold-adapted equine influenza viruses |
| US6177082B1 (en) | 1998-08-13 | 2001-01-23 | The University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Cold-adapted equine influenza viruses |
| AU4065500A (en) | 1999-04-13 | 2000-11-14 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Production of attenuated chimeric respiratory syncytial virus vaccines from cloned nucleotide sequences |
| ATE419369T1 (de) | 1999-07-09 | 2009-01-15 | Us Gov Health & Human Serv | Chimäre mensch-rinder respiratory syncytial virus vakzinen |
| US7820182B2 (en) * | 1999-07-09 | 2010-10-26 | The United States Of America As Represented By The Department Of Health And Human Services | Production of attenuated, human-bovine chimeric respiratory syncytial viruses for use in immunogenic compositions |
| AU2001249300B2 (en) | 2000-04-03 | 2006-02-16 | The University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Cold-adapted equine influenza viruses |
| EP1441762A1 (de) * | 2001-09-28 | 2004-08-04 | University Of South Florida | Rsv genexpressions impstoff |
| US7465456B2 (en) * | 2002-04-26 | 2008-12-16 | Medimmune, Llc | Multi plasmid system for the production of influenza virus |
| DK1499348T3 (en) | 2002-04-26 | 2015-01-05 | Medimmune Llc | PROCEDURE FOR PREPARING INFECTIOUS INFLUENZA B-VIRA IN CELL CULTURE |
| JP2007531491A (ja) * | 2002-09-27 | 2007-11-08 | メディミューン・ヴァクシンズ・インコーポレーテッド | 呼吸器合胞体ウイルスにおける機能的突然変異 |
| WO2004083397A2 (en) * | 2003-03-18 | 2004-09-30 | Wyeth Holdings Corporation | Process for increasing rsv surface glycoprotein yields using a mutant strain of rsv |
| EP1613345B1 (de) * | 2003-03-28 | 2010-05-26 | MedImmune, LLC | Zusammensetzungen und verfahren mit dem respiratory syncytial virus untergruppe b stamm 9320 |
| US7566458B2 (en) | 2003-06-16 | 2009-07-28 | Medimmune, Llc | Influenza hemagglutinin and neuraminidase variants |
| EP1701738B1 (de) * | 2003-12-17 | 2015-03-11 | Wyeth LLC | Verfahren zur Herstellung von lagerstabilen RSV Zusammensetzungen |
| CA2551489C (en) | 2003-12-23 | 2013-09-03 | Gregory Duke | Multi plasmid system for the production of influenza virus |
| JP4980895B2 (ja) | 2004-05-25 | 2012-07-18 | メディミューン,エルエルシー | インフルエンザ赤血球凝集素およびノイラミニダーゼ変異体 |
| EP2471552B1 (de) | 2005-03-08 | 2015-05-06 | MedImmune, LLC | Reassortierte Influenza-Viren |
| WO2008133701A1 (en) * | 2006-07-21 | 2008-11-06 | Medimmune, Llc. | Methods and compositions for increasing replication capacity of an influenza virus |
| CN104140958A (zh) * | 2006-08-09 | 2014-11-12 | 米迪缪尼有限公司 | 流感血凝素和神经氨酸酶变体 |
| EP2674486A1 (de) * | 2007-06-18 | 2013-12-18 | MedImmune, LLC | Influenza-B-Viren mit Veränderungen im Hämagglutininpolypeptid |
| US20090017517A1 (en) * | 2007-07-13 | 2009-01-15 | Medimmune, Llc | Preparation of Negative-Stranded RNA Viruses by Electroporation |
| RU2523587C2 (ru) | 2008-07-11 | 2014-07-20 | МЕДИММЬЮН, ЭлЭлСи | Варианты гемагглютинина и нейрамидазы вируса гриппа |
| SG173642A1 (en) | 2009-02-12 | 2011-09-29 | Medimmune Llc | Influenza hemagglutinin and neuraminidase variants |
| GB201003630D0 (en) | 2010-03-04 | 2010-04-21 | Novartis Ag | Avian rotavirus |
| US9017694B2 (en) | 2011-10-07 | 2015-04-28 | Medimmune, Llc | Swine influenza hemagglutinin variants |
| PT3511015T (pt) * | 2012-04-13 | 2021-04-05 | Us Health | Vacina viva e atenuada e geneticamente estável contra o vírus sincicial respiratório e a sua produção |
| EP2968510B1 (de) * | 2013-03-14 | 2019-10-09 | President and Fellows of Harvard College | Zusammensetzungen von nanopartikeln |
| EP3798310A1 (de) | 2013-03-14 | 2021-03-31 | Emory University | Rekombinante rsv mit stillen mutationen, impfstoffe und zugehörige verfahren |
| MX2018005462A (es) | 2015-10-29 | 2018-08-01 | Univ Emory | Composiciones inmunogénicas de rsv quimérico y métodos de uso. |
| EP3923983A4 (de) | 2019-02-11 | 2023-02-22 | Emory University | Chimäre rsv- und hmpv-f-proteine, immunogene zusammensetzungen und verwendungsverfahren |
| RU2746280C1 (ru) * | 2020-08-03 | 2021-04-12 | Федеральное государственное бюджетное научное учреждение "Федеральный исследовательский центр фундаментальной и трансляционной медицины" (ФИЦ ФТМ) | Штамм респираторно-синцитиального вируса RSV/Novosibirsk/66Hl/2018 для использования в диагностике респираторно-синцитиальной вирусной инфекции и исследования эффективности противовирусных препаратов in vitro |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4122167A (en) * | 1977-02-09 | 1978-10-24 | Merck & Co., Inc. | Respiratory synctial vaccine |
| US4866034A (en) * | 1982-05-26 | 1989-09-12 | Ribi Immunochem Research Inc. | Refined detoxified endotoxin |
| US4800078A (en) * | 1987-05-28 | 1989-01-24 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Immunotherapeutic method of treating respiratory disease by intranasal administration of Igb |
| US5250298A (en) * | 1988-10-07 | 1993-10-05 | University Of Delaware | Live attenuated newcastle disease virus vaccines and preparation thereof |
-
1993
- 1993-04-19 IL IL10545693A patent/IL105456A/en not_active IP Right Cessation
- 1993-04-20 DE DE69325370T patent/DE69325370T2/de not_active Expired - Fee Related
- 1993-04-20 WO PCT/US1993/003670 patent/WO1993021310A1/en not_active Ceased
- 1993-04-20 CA CA002118509A patent/CA2118509C/en not_active Expired - Fee Related
- 1993-04-20 DK DK93912315T patent/DK0640128T3/da active
- 1993-04-20 AU AU42907/93A patent/AU683840B2/en not_active Ceased
- 1993-04-20 HU HU9403023A patent/HU220189B/hu not_active IP Right Cessation
- 1993-04-20 AT AT93912315T patent/ATE181359T1/de not_active IP Right Cessation
- 1993-04-20 ES ES93912315T patent/ES2132233T3/es not_active Expired - Lifetime
- 1993-04-20 EP EP93912315A patent/EP0640128B1/de not_active Expired - Lifetime
- 1993-04-20 UA UA94105948A patent/UA41315C2/uk unknown
- 1993-04-20 RU RU94045898A patent/RU2139729C1/ru not_active IP Right Cessation
- 1993-04-20 KR KR1019940703740A patent/KR100257171B1/ko not_active Expired - Fee Related
- 1993-04-20 MX MX9302278A patent/MX9302278A/es not_active IP Right Cessation
- 1993-04-20 JP JP51866393A patent/JP3883202B2/ja not_active Expired - Fee Related
- 1993-04-20 NZ NZ252857A patent/NZ252857A/en not_active IP Right Cessation
-
1994
- 1994-10-21 US US08/327,263 patent/US5922326A/en not_active Expired - Lifetime
-
1995
- 1995-05-30 US US08/453,304 patent/US6284254B1/en not_active Expired - Lifetime
- 1995-05-30 US US08/453,294 patent/US5882651A/en not_active Expired - Lifetime
-
1999
- 1999-09-15 GR GR990402303T patent/GR3031208T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR950701382A (ko) | 1995-03-23 |
| US5882651A (en) | 1999-03-16 |
| KR100257171B1 (ko) | 2000-05-15 |
| CA2118509A1 (en) | 1993-10-28 |
| HUT69992A (en) | 1995-09-28 |
| MX9302278A (es) | 1994-07-29 |
| EP0640128A1 (de) | 1995-03-01 |
| UA41315C2 (uk) | 2001-09-17 |
| EP0640128B1 (de) | 1999-06-16 |
| IL105456A (en) | 1996-12-05 |
| DK0640128T3 (da) | 1999-11-22 |
| DE69325370T2 (de) | 1999-10-14 |
| AU683840B2 (en) | 1997-11-27 |
| HU9403023D0 (en) | 1994-12-28 |
| US5922326A (en) | 1999-07-13 |
| JP3883202B2 (ja) | 2007-02-21 |
| DE69325370D1 (de) | 1999-07-22 |
| RU2139729C1 (ru) | 1999-10-20 |
| JPH07505891A (ja) | 1995-06-29 |
| WO1993021310A1 (en) | 1993-10-28 |
| AU4290793A (en) | 1993-11-18 |
| IL105456A0 (en) | 1993-08-18 |
| US6284254B1 (en) | 2001-09-04 |
| CA2118509C (en) | 2009-05-19 |
| GR3031208T3 (en) | 1999-12-31 |
| RU94045898A (ru) | 1996-09-20 |
| ES2132233T3 (es) | 1999-08-16 |
| NZ252857A (en) | 1997-06-24 |
| ATE181359T1 (de) | 1999-07-15 |
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| HPC4 | Succession in title of patentee |
Owner name: THE UNITED STATES OF AMERICA AS REPRESENTED BY THE Owner name: WYETH (DELAWARE ALLAMBAN BEJEGYZETT CEG), US |
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| MM4A | Lapse of definitive patent protection due to non-payment of fees |