HUE035106T2 - Equipment for treating cancerous tumors within the body with an electric field directed to a desired location - Google Patents
Equipment for treating cancerous tumors within the body with an electric field directed to a desired location Download PDFInfo
- Publication number
- HUE035106T2 HUE035106T2 HUE06765476A HUE06765476A HUE035106T2 HU E035106 T2 HUE035106 T2 HU E035106T2 HU E06765476 A HUE06765476 A HU E06765476A HU E06765476 A HUE06765476 A HU E06765476A HU E035106 T2 HUE035106 T2 HU E035106T2
- Authority
- HU
- Hungary
- Prior art keywords
- field
- electrodes
- conductor
- impedance
- rod
- Prior art date
Links
- 230000005684 electric field Effects 0.000 title claims description 32
- 206010028980 Neoplasm Diseases 0.000 title claims description 14
- 201000011510 cancer Diseases 0.000 title description 3
- 239000011324 bead Substances 0.000 claims description 19
- 239000007787 solid Substances 0.000 claims description 15
- 239000004020 conductor Substances 0.000 claims description 9
- 239000000463 material Substances 0.000 claims description 7
- 239000004033 plastic Substances 0.000 claims description 6
- 229920003023 plastic Polymers 0.000 claims description 6
- 229920006362 Teflon® Polymers 0.000 claims description 5
- 230000009975 flexible effect Effects 0.000 claims description 5
- 239000004809 Teflon Substances 0.000 claims description 4
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 claims description 4
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 claims description 4
- 229910052737 gold Inorganic materials 0.000 claims description 4
- 239000010931 gold Substances 0.000 claims description 4
- 229920001296 polysiloxane Polymers 0.000 claims description 4
- 229920000915 polyvinyl chloride Polymers 0.000 claims description 4
- 239000004800 polyvinyl chloride Substances 0.000 claims description 3
- 229910001220 stainless steel Inorganic materials 0.000 claims description 3
- 239000010935 stainless steel Substances 0.000 claims description 3
- 239000010936 titanium Substances 0.000 claims description 3
- 229910052719 titanium Inorganic materials 0.000 claims description 3
- 230000002401 inhibitory effect Effects 0.000 claims description 2
- 125000006850 spacer group Chemical group 0.000 claims 3
- 239000000835 fiber Substances 0.000 claims 1
- 150000004676 glycans Chemical class 0.000 claims 1
- 229920001282 polysaccharide Polymers 0.000 claims 1
- 239000005017 polysaccharide Substances 0.000 claims 1
- 210000001519 tissue Anatomy 0.000 description 20
- 208000031968 Cadaver Diseases 0.000 description 12
- 239000000499 gel Substances 0.000 description 11
- 238000004088 simulation Methods 0.000 description 9
- 229910052751 metal Inorganic materials 0.000 description 6
- 239000002184 metal Substances 0.000 description 6
- 210000003205 muscle Anatomy 0.000 description 4
- 210000000056 organ Anatomy 0.000 description 4
- 210000004556 brain Anatomy 0.000 description 3
- 230000003902 lesion Effects 0.000 description 3
- 229920000642 polymer Polymers 0.000 description 3
- 229920002223 polystyrene Polymers 0.000 description 3
- 239000004793 Polystyrene Substances 0.000 description 2
- 210000003484 anatomy Anatomy 0.000 description 2
- 239000000560 biocompatible material Substances 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 238000004364 calculation method Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 229920001971 elastomer Polymers 0.000 description 2
- 238000009413 insulation Methods 0.000 description 2
- 239000012212 insulator Substances 0.000 description 2
- 201000001441 melanoma Diseases 0.000 description 2
- 230000010076 replication Effects 0.000 description 2
- 206010006187 Breast cancer Diseases 0.000 description 1
- 208000026310 Breast neoplasm Diseases 0.000 description 1
- 208000032612 Glial tumor Diseases 0.000 description 1
- 206010018338 Glioma Diseases 0.000 description 1
- RRHGJUQNOFWUDK-UHFFFAOYSA-N Isoprene Chemical compound CC(=C)C=C RRHGJUQNOFWUDK-UHFFFAOYSA-N 0.000 description 1
- 206010027465 Metastases to skin Diseases 0.000 description 1
- 238000002679 ablation Methods 0.000 description 1
- 230000002238 attenuated effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 210000000481 breast Anatomy 0.000 description 1
- 210000001072 colon Anatomy 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 208000035250 cutaneous malignant susceptibility to 1 melanoma Diseases 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000003292 diminished effect Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 210000004884 grey matter Anatomy 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 239000000017 hydrogel Substances 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 239000011810 insulating material Substances 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 210000001672 ovary Anatomy 0.000 description 1
- 210000000496 pancreas Anatomy 0.000 description 1
- 206010033675 panniculitis Diseases 0.000 description 1
- 229920001195 polyisoprene Polymers 0.000 description 1
- 210000002307 prostate Anatomy 0.000 description 1
- 206010040882 skin lesion Diseases 0.000 description 1
- 231100000444 skin lesion Toxicity 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 210000004304 subcutaneous tissue Anatomy 0.000 description 1
- 210000004885 white matter Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/40—Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Electrotherapy Devices (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US68899805P | 2005-06-08 | 2005-06-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE035106T2 true HUE035106T2 (en) | 2018-05-02 |
Family
ID=37074613
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE06765476A HUE035106T2 (en) | 2005-06-08 | 2006-06-08 | Equipment for treating cancerous tumors within the body with an electric field directed to a desired location |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20060282122A1 (es) |
| EP (1) | EP1899001B1 (es) |
| JP (2) | JP5451067B2 (es) |
| CN (1) | CN101287519B (es) |
| CA (1) | CA2611398C (es) |
| DK (1) | DK1899001T3 (es) |
| ES (1) | ES2651812T3 (es) |
| HU (1) | HUE035106T2 (es) |
| PL (1) | PL1899001T3 (es) |
| PT (1) | PT1899001T (es) |
| WO (1) | WO2006131817A1 (es) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7136699B2 (en) * | 2002-10-02 | 2006-11-14 | Standen, Ltd. | Apparatus for destroying dividing cells |
| US8447395B2 (en) * | 2000-02-17 | 2013-05-21 | Novocure Ltd | Treating bacteria with electric fields |
| US7805201B2 (en) | 2000-02-17 | 2010-09-28 | Standen Ltd. | Treating a tumor or the like with an electric field |
| CN1416466A (zh) | 2000-02-17 | 2003-05-07 | 约朗姆·帕尔蒂 | 破坏正在分裂的细胞的方法和装置 |
| US8175698B2 (en) | 2000-02-17 | 2012-05-08 | Novocure Ltd. | Treating bacteria with electric fields |
| DE602005020504D1 (de) * | 2004-12-07 | 2010-05-20 | Standen Ltd | Vivo über einen längeren zeitraum |
| DK1899001T3 (en) * | 2005-06-08 | 2017-12-04 | Novocure Ltd | DEVICE FOR CANCER TREATMENT WITH ELECTRIC FIELDS MADE FOR DESIRED LOCATIONS IN A BODY |
| CN101321555B (zh) * | 2005-10-03 | 2020-12-08 | 诺沃库勒有限责任公司 | 优化电场特征以增加电场在增殖细胞上的效果 |
| US8019414B2 (en) | 2006-04-05 | 2011-09-13 | Novocure Ltd. | Treating cancer using electromagnetic fields in combination with other treatment regimens |
| JP5457183B2 (ja) | 2006-09-14 | 2014-04-02 | ラジュール・テクノロジーズ・エルエルシイ | 癌細胞を破壊する装置及び方法 |
| DK2167194T3 (en) * | 2007-03-06 | 2017-06-19 | Novocure Ltd | TREATMENT OF CANCER USING ELECTROMAGNETIC FIELDS IN COMBINATION WITH PHOTODYNAMIC THERAPY |
| EP2183024B1 (en) * | 2007-08-14 | 2019-05-15 | Novocure Ltd. | Treating parasites with electric fields |
| CA2699782C (en) | 2007-09-14 | 2017-04-11 | Lazure Technologies, Llc | Prostate cancer ablation |
| WO2009036457A1 (en) | 2007-09-14 | 2009-03-19 | Lazure Technologies, Llc | Multi-layer electrode ablation probe and related methods |
| US8728139B2 (en) | 2009-04-16 | 2014-05-20 | Lazure Technologies, Llc | System and method for energy delivery to a tissue using an electrode array |
| US9526911B1 (en) | 2010-04-27 | 2016-12-27 | Lazure Scientific, Inc. | Immune mediated cancer cell destruction, systems and methods |
| US9655669B2 (en) | 2013-05-06 | 2017-05-23 | Novocure Limited | Optimizing treatment using TTFields by changing the frequency during the course of long term tumor treatment |
| US10779875B2 (en) | 2013-05-06 | 2020-09-22 | Novocure Gmbh | Optimizing treatment using TTfields by changing the frequency during the course of long term tumor treatment |
| DE102014010907A1 (de) * | 2014-07-23 | 2016-01-28 | Fresenius Medical Care Deutschland Gmbh | Vorrichtung zur extrakorporalen Entfernung proteingebundener Toxine |
| US10188851B2 (en) | 2015-10-28 | 2019-01-29 | Novocure Limited | TTField treatment with optimization of electrode positions on the head based on MRI-based conductivity measurements |
| JP6980706B2 (ja) * | 2016-06-30 | 2021-12-15 | ノボキュア ゲーエムベーハー | 身体への腫瘍治療電場の長手方向伝達用のアレイ |
| US12403306B2 (en) | 2017-10-23 | 2025-09-02 | Cardiac Pacemakers, Inc. | Electric field shaping leads for treatment of cancer |
| US11338135B2 (en) | 2017-10-23 | 2022-05-24 | Cardiac Pacemakers, Inc. | Medical devices for cancer therapy with electric field shaping elements |
| WO2020102312A1 (en) | 2018-11-13 | 2020-05-22 | The Methodist Hospital | Method and apparatus for oncomagnetic treatement |
| CN113727753B (zh) | 2019-04-22 | 2024-09-13 | 波士顿科学国际有限公司 | 用于癌症治疗的电刺激装置 |
| WO2020219337A1 (en) * | 2019-04-22 | 2020-10-29 | Boston Scientific Scimed, Inc. | Systems for administering electrical stimulation to treat cancer |
| US12109412B2 (en) | 2019-04-22 | 2024-10-08 | Boston Scientific Scimed, Inc. | Combination electrical and chemotherapeutic treatment of cancer |
| US11712561B2 (en) | 2019-04-23 | 2023-08-01 | Boston Scientific Scimed, Inc. | Electrical stimulation with thermal treatment or thermal monitoring |
| WO2020219519A1 (en) | 2019-04-23 | 2020-10-29 | Boston Scientific Scimed, Inc. | Electrodes for electrical stimulation to treat cancer |
| US11607542B2 (en) | 2019-04-23 | 2023-03-21 | Boston Scientific Scimed, Inc. | Electrical stimulation for cancer treatment with internal and external electrodes |
| JP7670721B6 (ja) | 2019-12-31 | 2025-06-06 | ノボキュア ゲーエムベーハー | 振幅調整およびチャネルの切り替え中のスパイクを防止する高電圧、高効率正弦波発生器 |
| MX2022006136A (es) | 2019-12-31 | 2022-06-17 | Novocure Gmbh | Matrices para suministrar campos de tratamiento de tumores (ttfields) con elementos de electrodos y sensores de temperatura accesibles individualmente. |
| CN115515674A (zh) | 2020-02-24 | 2022-12-23 | 波士顿科学国际有限公司 | 用于治疗胰腺癌的系统和方法 |
| WO2021198864A1 (en) | 2020-03-30 | 2021-10-07 | Novocure Gmbh | Intravenous / intra-spinal / intra-cavity / intraventricular delivery of ttfields (tumor treating fields) for treating cancer and metastases |
| CN111420271A (zh) * | 2020-04-02 | 2020-07-17 | 河北普尼医疗科技有限公司 | 一种基于头部肿瘤治疗的电极贴片定位方法 |
| MX2022010015A (es) | 2020-04-24 | 2022-09-05 | Novocure Gmbh | Uso de campos electricos alternos para aumentar la permeabilidad de la barrera hematoencefalica. |
| TWI885157B (zh) * | 2020-06-02 | 2025-06-01 | 瑞士商諾沃庫勒有限責任公司 | 用於產生電場之設備及方法 |
| WO2021257967A1 (en) | 2020-06-19 | 2021-12-23 | The Methodist Hospital Dba Houston Methodist Hospital | Method and apparatus for oncomagnetic treatment |
| US11818943B2 (en) | 2020-06-25 | 2023-11-14 | Novocure Gmbh | Fabricating organic light emitting diodes (OLEDs) using tubulin |
| TWI815047B (zh) * | 2020-10-16 | 2023-09-11 | 瑞士商諾沃庫勒有限責任公司 | 藉由使用TTFields活化STING途徑以降低癌細胞生存力的方法 |
| TWI869971B (zh) * | 2020-10-16 | 2025-01-11 | 瑞士商諾沃庫勒有限責任公司 | 藉由使用TTFields活化STING途徑以降低癌細胞生存力的方法 |
| EP4271466A2 (en) * | 2021-03-18 | 2023-11-08 | Novocure Gmbh | Constructing a 3d phantom with liquid hydrogel |
| EP4363047B1 (en) * | 2021-06-30 | 2025-03-19 | Novocure GmbH | Nonconductive field guide for resection cavity, and systems of using same |
| US20230218894A1 (en) * | 2022-01-11 | 2023-07-13 | Mayo Foundation For Medical Education And Research | Implantable cancer therapy electrodes with reduced mri artifacts |
| CN117959603B (zh) * | 2024-02-02 | 2025-08-22 | 赛福凯尔(绍兴)医疗科技有限公司 | 一种基于人体自然腔道的电场增强引导系统及其应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3991770A (en) * | 1974-01-24 | 1976-11-16 | Leveen Harry H | Method for treating benign and malignant tumors utilizing radio frequency, electromagnetic radiation |
| JPH0787865B2 (ja) * | 1986-06-13 | 1995-09-27 | オリンパス光学工業株式会社 | 体内加温装置 |
| JPS63192460A (ja) * | 1987-02-05 | 1988-08-09 | オリンパス光学工業株式会社 | 体内留置装置 |
| JPH01121069A (ja) * | 1987-11-04 | 1989-05-12 | Omron Tateisi Electron Co | 高周波温熱治療用加温促進装置 |
| JP3493078B2 (ja) * | 1995-06-07 | 2004-02-03 | 山本ビニター株式会社 | 超短波加温治療装置 |
| US5873849A (en) * | 1997-04-24 | 1999-02-23 | Ichor Medical Systems, Inc. | Electrodes and electrode arrays for generating electroporation inducing electrical fields |
| US6503231B1 (en) * | 1998-06-10 | 2003-01-07 | Georgia Tech Research Corporation | Microneedle device for transport of molecules across tissue |
| US6868289B2 (en) * | 2002-10-02 | 2005-03-15 | Standen Ltd. | Apparatus for treating a tumor or the like and articles incorporating the apparatus for treatment of the tumor |
| DK1899001T3 (en) * | 2005-06-08 | 2017-12-04 | Novocure Ltd | DEVICE FOR CANCER TREATMENT WITH ELECTRIC FIELDS MADE FOR DESIRED LOCATIONS IN A BODY |
-
2006
- 2006-06-08 DK DK06765476.4T patent/DK1899001T3/en active
- 2006-06-08 ES ES06765476.4T patent/ES2651812T3/es active Active
- 2006-06-08 WO PCT/IB2006/001500 patent/WO2006131817A1/en not_active Ceased
- 2006-06-08 EP EP06765476.4A patent/EP1899001B1/en active Active
- 2006-06-08 JP JP2008515307A patent/JP5451067B2/ja active Active
- 2006-06-08 CN CN200680026027.1A patent/CN101287519B/zh active Active
- 2006-06-08 HU HUE06765476A patent/HUE035106T2/en unknown
- 2006-06-08 PL PL06765476T patent/PL1899001T3/pl unknown
- 2006-06-08 US US11/422,998 patent/US20060282122A1/en not_active Abandoned
- 2006-06-08 PT PT67654764T patent/PT1899001T/pt unknown
- 2006-06-08 CA CA2611398A patent/CA2611398C/en active Active
-
2012
- 2012-11-05 JP JP2012243678A patent/JP2013046820A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP5451067B2 (ja) | 2014-03-26 |
| CN101287519A (zh) | 2008-10-15 |
| JP2013046820A (ja) | 2013-03-07 |
| US20060282122A1 (en) | 2006-12-14 |
| DK1899001T3 (en) | 2017-12-04 |
| EP1899001B1 (en) | 2017-10-25 |
| PL1899001T3 (pl) | 2018-06-29 |
| EP1899001A1 (en) | 2008-03-19 |
| ES2651812T3 (es) | 2018-01-29 |
| CA2611398C (en) | 2018-09-11 |
| PT1899001T (pt) | 2017-12-01 |
| WO2006131817A1 (en) | 2006-12-14 |
| CN101287519B (zh) | 2014-10-29 |
| CA2611398A1 (en) | 2006-12-14 |
| JP2008541974A (ja) | 2008-11-27 |
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