HUP9902121A3 - Indole derivatives as antagonists of gonadotropin releasing hormone and pharmaceutical compositions containing them - Google Patents
Indole derivatives as antagonists of gonadotropin releasing hormone and pharmaceutical compositions containing themInfo
- Publication number
- HUP9902121A3 HUP9902121A3 HU9902121A HUP9902121A HUP9902121A3 HU P9902121 A3 HUP9902121 A3 HU P9902121A3 HU 9902121 A HU9902121 A HU 9902121A HU P9902121 A HUP9902121 A HU P9902121A HU P9902121 A3 HUP9902121 A3 HU P9902121A3
- Authority
- HU
- Hungary
- Prior art keywords
- antagonists
- pharmaceutical compositions
- compositions containing
- releasing hormone
- indole derivatives
- Prior art date
Links
- 239000000579 Gonadotropin-Releasing Hormone Substances 0.000 title 1
- 101000857870 Squalus acanthias Gonadoliberin Proteins 0.000 title 1
- 239000005557 antagonist Substances 0.000 title 1
- 229940054051 antipsychotic indole derivative Drugs 0.000 title 1
- XLXSAKCOAKORKW-AQJXLSMYSA-N gonadorelin Chemical compound C([C@@H](C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1[C@@H](CCC1)C(=O)NCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H](CC=1N=CNC=1)NC(=O)[C@H]1NC(=O)CC1)C1=CC=C(O)C=C1 XLXSAKCOAKORKW-AQJXLSMYSA-N 0.000 title 1
- 229940035638 gonadotropin-releasing hormone Drugs 0.000 title 1
- 150000002475 indoles Chemical class 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C07D209/16—Tryptamines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Reproductive Health (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US863495P | 1995-12-14 | 1995-12-14 | |
| GBGB9603369.1A GB9603369D0 (en) | 1996-02-16 | 1996-02-16 | Antagonists of gonadotropin releasing hormone |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP9902121A2 HUP9902121A2 (hu) | 1999-10-28 |
| HUP9902121A3 true HUP9902121A3 (en) | 2001-05-28 |
Family
ID=26308742
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU9902121A HUP9902121A3 (en) | 1995-12-14 | 1996-12-10 | Indole derivatives as antagonists of gonadotropin releasing hormone and pharmaceutical compositions containing them |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0871624A1 (cs) |
| JP (2) | JPH11501329A (cs) |
| KR (1) | KR19990072124A (cs) |
| CN (1) | CN1208413A (cs) |
| AU (1) | AU709090B2 (cs) |
| CA (1) | CA2240048A1 (cs) |
| CZ (1) | CZ183298A3 (cs) |
| EA (1) | EA000829B1 (cs) |
| EE (1) | EE9800181A (cs) |
| HU (1) | HUP9902121A3 (cs) |
| IL (1) | IL124613A0 (cs) |
| MX (1) | MX9804850A (cs) |
| NO (1) | NO982731L (cs) |
| NZ (1) | NZ325014A (cs) |
| PL (1) | PL327132A1 (cs) |
| SK (1) | SK77598A3 (cs) |
| WO (1) | WO1997021703A1 (cs) |
Families Citing this family (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL180523B1 (pl) | 1994-04-01 | 2001-02-28 | Eli Lilly & Co | Nowy zwiazek, pochodna 1H-indolo-3-glioksylamidu i srodek farmaceutyczny PL PL PL PL PL PL PL PL PL PL |
| WO1997021435A1 (en) * | 1995-12-14 | 1997-06-19 | Merck & Co., Inc. | Antagonists of gonadotropin releasing hormone |
| US6200957B1 (en) | 1995-12-14 | 2001-03-13 | Merck & Co., Inc. | Antagonists of gonadotropin releasing hormone |
| US5981550A (en) * | 1997-06-05 | 1999-11-09 | Merck & Co., Inc. | Antagonists of gonadotropin releasing hormone |
| US5985901A (en) * | 1997-06-05 | 1999-11-16 | Merck & Co., Inc. | Antagonists of gonadotropin releasing hormone |
| US6156767A (en) * | 1997-06-05 | 2000-12-05 | Merck & Co., Inc. | Antagonists of gonadotropin releasing hormone |
| AU729752B2 (en) * | 1997-06-05 | 2001-02-08 | Merck & Co., Inc. | Antagonists of gonadotropin releasing hormone |
| WO1998055123A1 (en) * | 1997-06-05 | 1998-12-10 | Merck & Co., Inc. | Antagonists of gonadotropin releasing hormone |
| WO1998055479A1 (en) * | 1997-06-05 | 1998-12-10 | Merck & Co., Inc. | Antagonists of gonadotropin releasing hormone |
| US6004984A (en) * | 1997-06-05 | 1999-12-21 | Merck & Co., Inc. | Antagonists of gonadotropin releasing hormone |
| AU7806998A (en) * | 1997-06-05 | 1998-12-21 | Merck & Co., Inc. | Antagonists of gonadotropin releasing hormone |
| US6156772A (en) * | 1997-06-05 | 2000-12-05 | Merck & Co., Inc. | Antagonists of gonadotropin releasing hormone |
| GB9718833D0 (en) | 1997-09-04 | 1997-11-12 | Merck Sharp & Dohme | Therapeutic agents |
| JP2001520997A (ja) * | 1997-10-28 | 2001-11-06 | メルク エンド カムパニー インコーポレーテッド | 性腺刺激ホルモン放出ホルモン拮抗薬 |
| JP2002503661A (ja) * | 1998-02-11 | 2002-02-05 | メルク エンド カムパニー インコーポレーテッド | 性腺刺激ホルモン放出ホルモン拮抗薬 |
| US6159975A (en) * | 1998-02-11 | 2000-12-12 | Merck & Co., Inc. | Antagonists of gonadotropin releasing hormone |
| JP2002505318A (ja) * | 1998-03-05 | 2002-02-19 | アゴーロン・ファーマシューティカルズ・インコーポレイテッド | 非ペプチドＧｎＲＨ因子 |
| US6077847A (en) * | 1998-04-02 | 2000-06-20 | Merck & Co., Inc. | Antagonists of gonadotropin releasing hormone |
| US6025366A (en) * | 1998-04-02 | 2000-02-15 | Merck & Co., Inc. | Antagonists of gonadotropin releasing hormone |
| US6228867B1 (en) | 1998-04-02 | 2001-05-08 | Merck & Co., Inc. | Antagonists of gonadotropin releasing hormone |
| US5998432A (en) * | 1998-04-02 | 1999-12-07 | Merck & Co., Inc. | Antagonists of gonadotropin releasing hormone |
| US6110931A (en) * | 1998-04-02 | 2000-08-29 | Merck & Co., Inc. | Antagonists of gonadotropin releasing hormone |
| US5985892A (en) * | 1998-04-02 | 1999-11-16 | Merck & Co., Ltd. | Antagonists of gonadotropin releasing hormone |
| US6346534B1 (en) | 1998-09-23 | 2002-02-12 | Neurocrine Biosciences, Inc. | Gonadotropin-releasing hormone receptor antagonists and methods relating thereto |
| EP1171125A1 (en) | 1999-03-10 | 2002-01-16 | Merck & Co., Inc. | 6-azaindole compounds as antagonists of gonadotropin releasing hormone |
| CA2367121A1 (en) | 1999-03-10 | 2000-09-14 | Merck & Co., Inc. | 6-azaindole compounds as antagonists of gonadotropin releasing hormone |
| AU3514200A (en) | 1999-03-10 | 2000-09-28 | Merck & Co., Inc. | 6-azaindole compounds as antagonists of gonadotropin releasing hormone |
| EP1161431A4 (en) * | 1999-03-10 | 2002-04-24 | Merck & Co Inc | 6-AZAINDOL COMPOUNDS AS AN ANTAGONISTS OF THE GONADOTROPIN RELEASE HORMONES |
| US6537998B1 (en) | 1999-10-15 | 2003-03-25 | Neurocrine Biosciences, Inc. | Gonadotropin-releasing hormone receptor antagonists and methods relating thereto |
| WO2001055119A2 (en) | 2000-01-25 | 2001-08-02 | Neurocrine Biosciences, Inc. | Gonadotropin-releasing hormone receptor antagonists and methods relating thereto |
| GB0022670D0 (en) | 2000-09-15 | 2000-11-01 | Astrazeneca Ab | Molecules |
| US6583153B2 (en) | 2000-12-12 | 2003-06-24 | Ortho-Mcneil Pharmaceutical, Inc. | 7-heterocyclyl quinoline and thieno[2,3-b]yridine derivatives useful as antagonists of gonadotropin releasing hormone |
| SE0100566D0 (sv) * | 2001-02-20 | 2001-02-20 | Astrazeneca Ab | Compounds |
| SE0101692D0 (sv) | 2001-05-14 | 2001-05-14 | Astrazeneca Ab | Compounds |
| EP1411941A2 (en) | 2001-08-02 | 2004-04-28 | Neurocrine Biosciences, Inc. | Pyridinone and pyridazinone derivatives as gonadotropin-releasing hormone receptor antagonists |
| JP2005500352A (ja) | 2001-08-02 | 2005-01-06 | ニューロクライン バイオサイエンシーズ， インコーポレイテッド | ゴナドトロピン放出ホルモンレセプター（ＧｎＲＨ）アンタゴニストとしての１，２，４−トリアジン−３，５−ジオン |
| WO2003011870A1 (en) | 2001-08-02 | 2003-02-13 | Neurocrine Biosciences, Inc. | Gonadotropin-releasing hormone receptor antagonists |
| AU2002324586B2 (en) | 2001-08-02 | 2008-04-24 | Neurocrine Biosciences, Inc. | 1,3,5-triazine-2,4,6-triones, preparation and use as gonadotropin-releasing hormone receptor antagonists |
| US6939883B2 (en) | 2001-08-02 | 2005-09-06 | Neurocrine Biosciences, Inc. | Gonadotropin-releasing hormone receptor antagonists and methods relating thereto |
| WO2003068769A1 (en) | 2002-02-12 | 2003-08-21 | Pfizer Inc. | Non-peptide compounds affecting the action of gonadotropin-releasing hormone (gnrh) |
| CA2489252A1 (en) | 2002-06-13 | 2003-12-24 | Pfizer Inc. | Non-peptide gnrh agents, pharmaceutical compositions and methods for their use |
| DE60314158T2 (de) | 2002-08-21 | 2008-01-31 | Astrazeneca Ab | Pyrazolderivate als gnrh-inhibitoren |
| GB0219472D0 (en) * | 2002-08-21 | 2002-10-02 | Astrazeneca Ab | Chemical compounds |
| TW200413351A (en) | 2002-08-21 | 2004-08-01 | Astrazeneca Ab | Chemical compounds |
| JP2006508050A (ja) | 2002-08-21 | 2006-03-09 | アストラゼネカ アクチボラグ | ゴナドトロピン放出ホルモンのアンタゴニストとしてのチエノピロール化合物 |
| TW200407127A (en) | 2002-08-21 | 2004-05-16 | Astrazeneca Ab | Chemical compounds |
| ES2387495T3 (es) | 2003-07-07 | 2012-09-25 | Neurocrine Biosciences, Inc. | Arilpirimidinas útiles en el tratamiento de trastornos relacionados con las hormonas sexuales, tales como endometriosis, cáncer de próstata y similares |
| DE602004020638D1 (de) | 2003-07-07 | 2009-05-28 | Neurocrine Biosciences Inc | Pyrimidin-2,4-dion-derivate als gonadotropin freisetzende hormon-rezeptor-antagonisten |
| AU2004257639B2 (en) | 2003-07-07 | 2011-01-06 | Neurocrine Biosciences, Inc. | Pyrimidine-2, 4-dione derivatives as gonadotropin-releasing hormone receptor antagonists |
| DE102004033902A1 (de) | 2004-07-14 | 2006-02-16 | Zentaris Gmbh | Neue Tetrahydrocarbazolderivate mit verbesserter biologischer Wirkung und verbesserter Löslichkeit als Liganden für G-Protein gekoppelte Rezeptoren (GPCR's) |
| US8957070B2 (en) * | 2005-04-20 | 2015-02-17 | Takeda Pharmaceutical Company Limited | Glucokinase activator compounds, methods of activating glucokinase and methods of treating diabetes and obesity |
| CN101233121A (zh) * | 2005-06-10 | 2008-07-30 | 彼帕科学公司 | Parp调节剂和癌症的治疗 |
| EP2095818A1 (en) | 2008-02-29 | 2009-09-02 | AEterna Zentaris GmbH | Use of LHRH antagonists at non-castrating doses |
| TW201130854A (en) | 2009-12-22 | 2011-09-16 | Bayer Schering Pharma Ag | Pyridinone derivatives and pharmaceutical compositions thereof |
| WO2012175514A1 (en) | 2011-06-21 | 2012-12-27 | Bayer Intellectual Property Gmbh | Pyridinone derivatives and pharmaceutical compositions thereof |
| US9586957B2 (en) * | 2013-03-27 | 2017-03-07 | VIIV Healthcare UK (No.5) Limited | 2-keto amide derivatives as HIV attachment inhibitors |
| CN115867543A (zh) | 2020-06-12 | 2023-03-28 | 弗特克斯药品有限公司 | Apol1抑制剂的固体形式及其使用方法 |
| CN113527254B (zh) * | 2021-07-07 | 2022-05-03 | 北京华氏信华科生物科技有限公司 | 7-甲氧基-1h-吲哚类化合物、制备方法、药物组合物及应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA795239B (en) * | 1978-10-12 | 1980-11-26 | Glaxo Group Ltd | Heterocyclic compounds |
| US4544663A (en) * | 1984-05-07 | 1985-10-01 | Sandoz, Inc. | Indolamine derivatives as anti-fertility agents |
| US5030640A (en) * | 1989-01-05 | 1991-07-09 | Merck & Co., Inc. | Novel β-adrenergic agonists and pharmaceutical compositions thereof |
| TW449600B (en) * | 1994-04-19 | 2001-08-11 | Takeda Chemical Industries Ltd | Condensed-ring thiophene derivatives, their production and use |
| CN1208412A (zh) * | 1995-12-14 | 1999-02-17 | 麦克公司 | 促性腺激素释放激素拮抗剂 |
-
1996
- 1996-12-10 SK SK775-98A patent/SK77598A3/sk unknown
- 1996-12-10 EP EP96943624A patent/EP0871624A1/en not_active Withdrawn
- 1996-12-10 CZ CZ981832A patent/CZ183298A3/cs unknown
- 1996-12-10 WO PCT/US1996/019443 patent/WO1997021703A1/en not_active Ceased
- 1996-12-10 EA EA199800564A patent/EA000829B1/ru not_active IP Right Cessation
- 1996-12-10 JP JP9522123A patent/JPH11501329A/ja active Pending
- 1996-12-10 AU AU12819/97A patent/AU709090B2/en not_active Ceased
- 1996-12-10 HU HU9902121A patent/HUP9902121A3/hu unknown
- 1996-12-10 EE EE9800181A patent/EE9800181A/xx unknown
- 1996-12-10 PL PL96327132A patent/PL327132A1/xx unknown
- 1996-12-10 IL IL12461396A patent/IL124613A0/xx unknown
- 1996-12-10 KR KR1019980704442A patent/KR19990072124A/ko not_active Withdrawn
- 1996-12-10 NZ NZ325014A patent/NZ325014A/en unknown
- 1996-12-10 CN CN96199901A patent/CN1208413A/zh active Pending
- 1996-12-10 CA CA002240048A patent/CA2240048A1/en not_active Abandoned
-
1998
- 1998-06-12 NO NO982731A patent/NO982731L/no not_active Application Discontinuation
- 1998-06-15 MX MX9804850A patent/MX9804850A/es unknown
-
2000
- 2000-02-08 JP JP2000030819A patent/JP2000186039A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| IL124613A0 (en) | 1998-12-06 |
| JP2000186039A (ja) | 2000-07-04 |
| HUP9902121A2 (hu) | 1999-10-28 |
| EA000829B1 (ru) | 2000-04-24 |
| EA199800564A1 (ru) | 1998-12-24 |
| NZ325014A (en) | 2000-06-23 |
| AU709090B2 (en) | 1999-08-19 |
| CN1208413A (zh) | 1999-02-17 |
| KR19990072124A (ko) | 1999-09-27 |
| SK77598A3 (en) | 1999-01-11 |
| PL327132A1 (en) | 1998-11-23 |
| MX9804850A (es) | 1998-09-30 |
| JPH11501329A (ja) | 1999-02-02 |
| NO982731D0 (no) | 1998-06-12 |
| EE9800181A (et) | 1998-12-15 |
| CA2240048A1 (en) | 1997-06-19 |
| WO1997021703A1 (en) | 1997-06-19 |
| EP0871624A1 (en) | 1998-10-21 |
| AU1281997A (en) | 1997-07-03 |
| NO982731L (no) | 1998-08-13 |
| CZ183298A3 (cs) | 1998-09-16 |
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