HUT49893A - Process for production of new crystallic formation and medical compositions containing it - Google Patents

Process for production of new crystallic formation and medical compositions containing it

Info

Publication number
HUT49893A
HUT49893A HU886374A HU637488A HUT49893A HU T49893 A HUT49893 A HU T49893A HU 886374 A HU886374 A HU 886374A HU 637488 A HU637488 A HU 637488A HU T49893 A HUT49893 A HU T49893A
Authority
HU
Hungary
Prior art keywords
crystallic
formation
new
production
compositions containing
Prior art date
Application number
HU886374A
Other languages
Hungarian (hu)
Other versions
HU203564B (en
Inventor
Danielle Giron
Martin List
Friedrich Richter
Yasuyuki Ulike
Hans P Weber
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of HUT49893A publication Critical patent/HUT49893A/en
Publication of HU203564B publication Critical patent/HU203564B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C07K7/645—Cyclosporins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
HU886374A 1987-12-21 1988-12-09 Process for producing new orthorombos cyclosporin without solvatation HU203564B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13623087A 1987-12-21 1987-12-21
US17261388A 1988-03-24 1988-03-24
US21254888A 1988-06-28 1988-06-28

Publications (2)

Publication Number Publication Date
HUT49893A true HUT49893A (en) 1989-11-28
HU203564B HU203564B (en) 1991-08-28

Family

ID=27384838

Family Applications (1)

Application Number Title Priority Date Filing Date
HU886374A HU203564B (en) 1987-12-21 1988-12-09 Process for producing new orthorombos cyclosporin without solvatation

Country Status (27)

Country Link
JP (1) JPH0791316B2 (en)
KR (1) KR100188305B1 (en)
AT (1) AT403163B (en)
AU (1) AU626274B2 (en)
BE (1) BE1002665A4 (en)
CA (1) CA1341396C (en)
CH (1) CH677926A5 (en)
CY (1) CY1799A (en)
DE (1) DE3843054C2 (en)
DK (1) DK175220B1 (en)
ES (1) ES2012580A6 (en)
FI (1) FI89065C (en)
FR (1) FR2624863B1 (en)
GB (1) GB2211848B (en)
GR (1) GR1002486B (en)
HK (1) HK102894A (en)
HU (1) HU203564B (en)
IE (1) IE62006B1 (en)
IL (1) IL88719A0 (en)
IT (1) IT1235356B (en)
LU (1) LU87409A1 (en)
MY (1) MY103943A (en)
NL (1) NL195096C (en)
NO (1) NO177228C (en)
NZ (1) NZ227384A (en)
SE (1) SE503174C2 (en)
SG (1) SG99494G (en)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5639724A (en) 1984-07-24 1997-06-17 Sandoz Ltd. Cyclosporin galenic forms
GB2222770B (en) * 1988-09-16 1992-07-29 Sandoz Ltd Pharmaceutical compositions containing cyclosporins
US6007840A (en) * 1988-09-16 1999-12-28 Novartis Ag Pharmaceutical compositions comprising cyclosporins
US7081445B2 (en) 1989-02-20 2006-07-25 Novartis Ag Cyclosporin galenic forms
US5294604A (en) * 1989-12-20 1994-03-15 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Method of treating ocular diseases by periocular administration of cyclosporine A or G
GB9105705D0 (en) * 1991-03-18 1991-05-01 Sandoz Ltd Improvements in or relating to organic compounds
US6262022B1 (en) 1992-06-25 2001-07-17 Novartis Ag Pharmaceutical compositions containing cyclosporin as the active agent
SG45449A1 (en) * 1992-05-13 1998-01-16 Sandoz Ltd Ophthalmic compositions
DK0589843T3 (en) 1992-09-25 2002-04-02 Novartis Ag Cyclosporin-containing pharmaceutical preparations
ATE218359T1 (en) 1994-11-03 2002-06-15 Novartis Erfind Verwalt Gmbh NEW PREPARATION FORMS OF CYCLOSPORIN FOR ORAL APPLICATION WITH SIMPLE COMPOSITION AND HIGH BIOAVAILABILITY AND METHOD FOR THE PRODUCTION THEREOF
US5962019A (en) * 1995-08-25 1999-10-05 Sangstat Medical Corporation Oral cyclosporin formulations
US5766629A (en) 1995-08-25 1998-06-16 Sangstat Medical Corporation Oral cyclosporin formulations
DE19544507B4 (en) 1995-11-29 2007-11-15 Novartis Ag Cyclosporin containing preparations
US6262054B1 (en) * 1996-02-01 2001-07-17 Sloan-Kettering Institute Of Cancer Research Combination therapy method for treating breast cancer using edatrexate
PT988046E (en) 1997-01-30 2004-12-31 Novartis Ag COMPOSITIONS OF OIL-FREE OIL CONTAINING CYCLOSPORINE A
TW581681B (en) 1998-02-20 2004-04-01 Nektar Therapeutics Liquid crystal forms of cyclosporin
US7732404B2 (en) 1999-12-30 2010-06-08 Dexcel Ltd Pro-nanodispersion for the delivery of cyclosporin
EP1706095B1 (en) 2004-01-20 2008-12-24 Allergan, Inc. Compositions for localized therapy of the eye, comprising preferably triamcinolone acetonide and hyaluronic acid
CN1763084B (en) * 2005-10-11 2010-04-21 山东新时代药业有限公司 Preparation method of high-purity cyclosporine A
UA113627C2 (en) 2011-05-27 2017-02-27 CRYSTAL FORM OF CYCLOSPORIN A, PHARMACEUTICAL COMPOSITION AND METHOD OF TREATMENT
JP6363506B2 (en) 2011-11-15 2018-07-25 アラーガン、インコーポレイテッドＡｌｌｅｒｇａｎ，Ｉｎｃｏｒｐｏｒａｔｅｄ Cyclosporine A2 suspension
CN108714137B (en) * 2011-11-15 2022-02-01 阿勒根公司 Thermostatible suspension of cyclosporin A form 2
CN104039813B (en) 2011-11-15 2017-08-29 阿勒根公司 cyclosporin A form 2 and preparation method thereof
KR102029513B1 (en) * 2011-11-15 2019-10-07 알러간, 인코포레이티드 Sustained action formulation of cyclosporin form 2
US20260132169A1 (en) * 2022-10-20 2026-05-14 Chugai Seiyaku Kabushiki Kaisha Method for producing cyclic peptide crystals

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH614931A5 (en) * 1975-11-04 1979-12-28 Sandoz Ag
CH640519A5 (en) * 1976-04-09 1984-01-13 Sandoz Ag Process for preparing a modified form of the antibiotic S 7481/F-1
US4117118A (en) * 1976-04-09 1978-09-26 Sandoz Ltd. Organic compounds
DE2819094A1 (en) * 1977-05-10 1978-11-23 Sandoz Ag CYCLOSPORIN DERIVATIVES, THEIR USE AND MANUFACTURING
CH637124A5 (en) * 1978-10-18 1983-07-15 Sandoz Ag Antibiotic, its preparation and use

Also Published As

Publication number Publication date
SE503174C2 (en) 1996-04-15
AU2705588A (en) 1989-06-22
NZ227384A (en) 1991-09-25
NL195096C (en) 2004-02-09
FI885869A0 (en) 1988-12-19
NL8803125A (en) 1989-07-17
CA1341396C (en) 2002-11-05
IE883779L (en) 1989-06-21
SE8804570D0 (en) 1988-12-19
NO177228B (en) 1995-05-02
ATA309588A (en) 1997-04-15
LU87409A1 (en) 1989-07-07
FI885869L (en) 1989-06-22
FI89065B (en) 1993-04-30
AT403163B (en) 1997-11-25
SG99494G (en) 1994-10-28
KR100188305B1 (en) 1999-06-01
GR1002486B (en) 1996-12-09
NO885625D0 (en) 1988-12-19
GB2211848A (en) 1989-07-12
IT8848690A0 (en) 1988-12-20
GB2211848B (en) 1991-11-06
IL88719A0 (en) 1989-07-31
SE8804570L (en) 1989-06-22
GR880100850A (en) 1994-03-31
DE3843054C2 (en) 2003-08-21
BE1002665A4 (en) 1991-04-30
JPH0791316B2 (en) 1995-10-04
DK175220B1 (en) 2004-07-12
KR890009975A (en) 1989-08-05
NO885625L (en) 1989-06-22
FI89065C (en) 1993-09-30
MY103943A (en) 1993-10-30
JPH01211598A (en) 1989-08-24
CH677926A5 (en) 1991-07-15
AU626274B2 (en) 1992-07-30
NO177228C (en) 1995-08-09
CY1799A (en) 1995-02-17
HU203564B (en) 1991-08-28
DK705488A (en) 1989-06-22
FR2624863A1 (en) 1989-06-23
HK102894A (en) 1994-09-30
FR2624863B1 (en) 1991-04-26
DK705488D0 (en) 1988-12-19
ES2012580A6 (en) 1990-04-01
DE3843054A1 (en) 1989-07-27
IT1235356B (en) 1992-06-30
GB8829556D0 (en) 1989-02-08
IE62006B1 (en) 1994-12-14

Similar Documents

Publication Publication Date Title
HUT47022A (en) Process for production of medical compositions
HUT50190A (en) Process for production of n-substituated 1-dezoxinogimiricin and 1-dezoxi-manno-nogimiricin and medical compositions containing them
HUT47561A (en) Process for production of 3-aryloxi-3-substituated propanamids and medical compositions containing them
HUT50151A (en) Process for production of benzo/b/pirans and piranpiridins and medical compositions containing them
HUT45895A (en) Process for production of serotomin antagonic compounds and medical preparatives containing such compositions
HUT47568A (en) Process for production of derivatives of tiazepine and medical compositions containing them
HUT46221A (en) Process for production of medical compositions containing alphusosine
HUT44941A (en) Process for producing stabile pharmaceutical compositions containing stimulating factor for colonies of granulocites
HUT42953A (en) Process for production of medical compositions
HUT40759A (en) Process for production of medical preparatives containing derivatives of antracyclin-glycosid
HUT45894A (en) Process for production of shaped medical plaster
HUT37628A (en) Process for production of acetil-eritromicin-stearat and medical preparatives containing - as reagent - such compounds
HU885511D0 (en) Process for production of crystallic aluminium-phosphate compositions
HUT45982A (en) Process for production of microlide compositions and medical preparatives containing such compositions
HUT37354A (en) Process for production of medical plaster
HUT50166A (en) Process for production of substituated 3,4-dihydro-rh-benzopiranes and medical compositions containing them
HUT47267A (en) Process for production of new pirasoline-derivatives and medical compositions containing them
HUT51247A (en) Process for production of aryl-zyanguananidins and medical compositions containing them
HUT45979A (en) Process for production of 5-phenil-2-oxasole-derivatives and medical compositions containing such compounds
HUT51901A (en) Process for production of new trombolitic ensimes
HUT50165A (en) Process for production of alkyl substituated n-benzopiramil lactanes and medical compositions containing them
HUT49342A (en) Process for production of derivatives of quinoline and medical compositions containing them
HUT47594A (en) Process for production of new derivatives of furanuronic acid and medical compositions containing them
HUT42455A (en) Process for production of derivatives of 5-substituated amino-piramidin and medical compositions containing thereof
HUT47563A (en) Process for production and transformation of polimorphe crystallic form of buspiron-hydrochlorids

Legal Events

Date Code Title Description
HPC4 Succession in title of patentee

Owner name: NOVARTIS AG, CH