HUT62005A - Process for producing thienoimidazole derivatives and pharmaceutical compositions comprising such compounds - Google Patents

Process for producing thienoimidazole derivatives and pharmaceutical compositions comprising such compounds

Info

Publication number
HUT62005A
HUT62005A HU913417A HU341791A HUT62005A HU T62005 A HUT62005 A HU T62005A HU 913417 A HU913417 A HU 913417A HU 341791 A HU341791 A HU 341791A HU T62005 A HUT62005 A HU T62005A
Authority
HU
Hungary
Prior art keywords
group
diseases
compounds
producing
pharmaceutical compositions
Prior art date
Application number
HU913417A
Other languages
English (en)
Other versions
HU913417D0 (en
Inventor
Takehiko Naka
Yoshiyuki Inada
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of HU913417D0 publication Critical patent/HU913417D0/hu
Publication of HUT62005A publication Critical patent/HUT62005A/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Lubricants (AREA)
HU913417A 1990-10-30 1991-10-30 Process for producing thienoimidazole derivatives and pharmaceutical compositions comprising such compounds HUT62005A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP29465590 1990-10-30
JP9208191 1991-04-23
JP15064391 1991-06-21

Publications (2)

Publication Number Publication Date
HU913417D0 HU913417D0 (en) 1992-01-28
HUT62005A true HUT62005A (en) 1993-03-29

Family

ID=27306934

Family Applications (1)

Application Number Title Priority Date Filing Date
HU913417A HUT62005A (en) 1990-10-30 1991-10-30 Process for producing thienoimidazole derivatives and pharmaceutical compositions comprising such compounds

Country Status (13)

Country Link
US (1) US5463073A (hu)
EP (1) EP0483683B1 (hu)
KR (1) KR920008046A (hu)
CN (1) CN1061973A (hu)
AT (1) ATE134633T1 (hu)
AU (1) AU636066B2 (hu)
DE (1) DE69117431T2 (hu)
FI (1) FI915099L (hu)
HU (1) HUT62005A (hu)
IE (1) IE913773A1 (hu)
MX (1) MX9101768A (hu)
NO (1) NO914236L (hu)
PT (1) PT99357A (hu)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0461040A1 (fr) * 1990-06-08 1991-12-11 Roussel Uclaf Dérivés de l'imidazole, leur procédé de préparation, les intermédiaires obtenus, leur application à titre de médicaments et les compositions pharmaceutiques les renfermant
TW274551B (hu) * 1991-04-16 1996-04-21 Takeda Pharm Industry Co Ltd
IL102183A (en) * 1991-06-27 1999-11-30 Takeda Chemical Industries Ltd Biphenyl substituted heterocyclic compounds their production and pharmaceutical compositions comprising them
EP0603712B1 (en) * 1992-12-22 2001-08-16 Takeda Chemical Industries, Ltd. Heterocyclic compounds having angiotensin II antagonistic activity and use thereof
CA2115985A1 (en) * 1993-02-25 1994-08-26 Kohei Nishikawa Vascular hypertrophy suppressor
JP3810020B2 (ja) * 1993-04-22 2006-08-16 武田薬品工業株式会社 腎疾患の予防または治療剤
US5721263A (en) * 1993-06-07 1998-02-24 Takeda Chemical Industries, Ltd. Pharmaceutical composition for angiotensin II-mediated diseases
CZ154994A3 (en) * 1993-07-02 1995-09-13 Senju Pharma Co Visual hypotensive agent
SE9903028D0 (sv) 1999-08-27 1999-08-27 Astra Ab New use
US7812044B2 (en) 2001-11-13 2010-10-12 Takeda Pharmaceutical Company Limited Anticancer agents
US7232828B2 (en) 2002-08-10 2007-06-19 Bethesda Pharmaceuticals, Inc. PPAR Ligands that do not cause fluid retention, edema or congestive heart failure
DE10341240A1 (de) 2003-09-08 2005-04-07 Aventis Pharma Deutschland Gmbh Substituierte Thienoimidazole, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
US20070282099A1 (en) * 2006-06-02 2007-12-06 Steffen Zahn Heterocyclic fused imidazolone, dioxolone, imidazolethione and dioxolethione monomers
JPWO2008143262A1 (ja) 2007-05-21 2010-08-12 武田薬品工業株式会社 複素環化合物およびその用途
MX354786B (es) 2007-06-04 2018-03-21 Synergy Pharmaceuticals Inc Agonistas de guanilato ciclasa utiles para el tratamiento de trastornos gastrointestinales, inflamacion, cancer y otros trastornos.
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
ES2522968T3 (es) 2008-06-04 2014-11-19 Synergy Pharmaceuticals Inc. Agonistas de guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos
AU2009270833B2 (en) 2008-07-16 2015-02-19 Bausch Health Ireland Limited Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
AU2014235215A1 (en) 2013-03-15 2015-10-01 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
AU2014235209B2 (en) 2013-03-15 2018-06-14 Bausch Health Ireland Limited Guanylate cyclase receptor agonists combined with other drugs
BR112015030326A2 (pt) 2013-06-05 2017-08-29 Synergy Pharmaceuticals Inc Agonistas ultrapuros de guanilato ciclase c, método de fabricar e usar os mesmos

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5671074A (en) * 1979-11-12 1981-06-13 Takeda Chem Ind Ltd 1,2-disubstituted-4-halogenoimidazole-5-acetic acid derivative
US4812462A (en) * 1986-04-01 1989-03-14 Warner-Lambert Company 4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid analogs having antihypertensive activity
CA1334092C (en) * 1986-07-11 1995-01-24 David John Carini Angiotensin ii receptor blocking imidazoles
US5015651A (en) * 1988-01-07 1991-05-14 E. I. Du Pont De Nemours And Company Treatment of hypertension with 1,2,4-angiotensin II antagonists
US4880804A (en) * 1988-01-07 1989-11-14 E. I. Du Pont De Nemours And Company Angiotensin II receptor blocking benzimidazoles
DE3928177A1 (de) * 1989-04-08 1991-02-28 Thomae Gmbh Dr K Benzimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
EP0400835A1 (en) * 1989-05-15 1990-12-05 Merck & Co. Inc. Substituted benzimidazoles as angiotensin II antagonists
GB8911854D0 (en) * 1989-05-23 1989-07-12 Ici Plc Heterocyclic compounds
US5164407A (en) * 1989-07-03 1992-11-17 Merck & Co., Inc. Substituted imidazo-fused 5-membered ring heterocycles and their use as angiotensin ii antagonsists
DE69013607T2 (de) * 1989-08-02 1995-03-02 Takeda Chemical Industries Ltd Pyrazol-Derivate, Verfahren zu deren Herstellung und Anwendung.
IE70593B1 (en) * 1989-09-29 1996-12-11 Eisai Co Ltd Biphenylmethane derivative the use of it and pharmacological compositions containing same
EP0461040A1 (fr) * 1990-06-08 1991-12-11 Roussel Uclaf Dérivés de l'imidazole, leur procédé de préparation, les intermédiaires obtenus, leur application à titre de médicaments et les compositions pharmaceutiques les renfermant

Also Published As

Publication number Publication date
KR920008046A (ko) 1992-05-27
EP0483683A3 (en) 1992-06-03
FI915099A0 (fi) 1992-08-11
EP0483683A2 (en) 1992-05-06
AU636066B2 (en) 1993-04-08
DE69117431T2 (de) 1996-06-13
PT99357A (pt) 1992-09-30
MX9101768A (es) 1992-06-05
DE69117431D1 (de) 1996-04-04
FI915099A7 (fi) 1992-08-11
IE913773A1 (en) 1992-05-22
HU913417D0 (en) 1992-01-28
NO914236D0 (no) 1991-10-29
CN1061973A (zh) 1992-06-17
FI915099L (fi) 1992-08-11
EP0483683B1 (en) 1996-02-28
NO914236L (no) 1992-05-04
US5463073A (en) 1995-10-31
AU8670791A (en) 1992-05-07
ATE134633T1 (de) 1996-03-15

Similar Documents

Publication Publication Date Title
HUT62005A (en) Process for producing thienoimidazole derivatives and pharmaceutical compositions comprising such compounds
TW274551B (hu)
CA2040955A1 (en) Benzimidazole derivatives, their production and use
EP0445811A3 (en) Nitrogen-containing heterocyclic compounds, their production and use
CA2047496A1 (en) Benzimidazoles, pharmaceutical compositions containing these compounds and processes for preparing them
CA2036304A1 (en) Pyrimidinedione derivatives, their production and use
ATE135701T1 (de) Imidazolderivate, starke und selektive angiotensin-ii-rezeptor-antagonisten
HUT71218A (en) Biphenyl derivatives optionally substituted with heterocyclices pharmaceutical compositions containing them and process for producing them
DE69120100D1 (de) Annelierte Thiophen-Derivate, ihre Herstellung und Verwendung
CA2536870A1 (en) Phenyl or pyridyl amide compounds as prostaglandin e2 antagonists
HUT46708A (en) Process for producing heterocyclic ketones and pharmaceutical compositions containing them as active components
HU9400910D0 (en) Nitrogenous heterocyclic compounds, process for producing them and pharmaceutical compositions containing them
HUT55384A (en) Process for producing benzimidazol derivaitves and pharmaceutical compositions containing them as active components
MXPA05010824A (es) Compuestos biciclicos como antagonistas del receptor nr2b.
PL241145A1 (en) Process for preparing novel,substituted guanidineheterocyclophenylamidines
IL100098A0 (en) 1,2,3,6-tetrahydropyridine derivatives,their preparation and pharmaceutical compositions containing them
KR950025037A (ko) 신규의 치환된 이미다졸 유도체 및 그의 제조방법

Legal Events

Date Code Title Description
DFA9 Temporary protection cancelled due to abandonment