HUT70496A - 3-phenylureido-azepin-2-one and benzazepin-2-one derivatives, process for producing thereof, and pharmaceutical compositions conprising them - Google Patents

3-phenylureido-azepin-2-one and benzazepin-2-one derivatives, process for producing thereof, and pharmaceutical compositions conprising them Download PDF

Info

Publication number
HUT70496A
HUT70496A HU9402195A HU9402195A HUT70496A HU T70496 A HUT70496 A HU T70496A HU 9402195 A HU9402195 A HU 9402195A HU 9402195 A HU9402195 A HU 9402195A HU T70496 A HUT70496 A HU T70496A
Authority
HU
Hungary
Prior art keywords
phenyl
oxo
ureido
tert
butyl
Prior art date
Application number
HU9402195A
Other languages
English (en)
Hungarian (hu)
Other versions
HU9402195D0 (en
Inventor
John A Lowe
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of HU9402195D0 publication Critical patent/HU9402195D0/hu
Publication of HUT70496A publication Critical patent/HUT70496A/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HU9402195A 1992-01-27 1992-12-16 3-phenylureido-azepin-2-one and benzazepin-2-one derivatives, process for producing thereof, and pharmaceutical compositions conprising them HUT70496A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US82567792A 1992-01-27 1992-01-27

Publications (2)

Publication Number Publication Date
HU9402195D0 HU9402195D0 (en) 1994-09-28
HUT70496A true HUT70496A (en) 1995-10-30

Family

ID=25244657

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9402195A HUT70496A (en) 1992-01-27 1992-12-16 3-phenylureido-azepin-2-one and benzazepin-2-one derivatives, process for producing thereof, and pharmaceutical compositions conprising them

Country Status (19)

Country Link
EP (1) EP0625145A1 (de)
JP (1) JPH07503465A (de)
KR (1) KR950700257A (de)
CN (1) CN1074903A (de)
AU (1) AU3276193A (de)
BR (1) BR9207071A (de)
CA (1) CA2117367A1 (de)
CZ (1) CZ391092A3 (de)
FI (1) FI943513A0 (de)
HU (1) HUT70496A (de)
IL (1) IL104472A0 (de)
MX (1) MX9300409A (de)
NO (1) NO942775L (de)
NZ (1) NZ245759A (de)
RU (1) RU94038063A (de)
TW (1) TW213901B (de)
WO (1) WO1993015059A1 (de)
YU (1) YU4393A (de)
ZA (1) ZA93582B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2097688A1 (es) * 1993-07-14 1997-04-01 Pfizer Hexahidroazepinonas y tetrahidrobenzazepinonas sustituidas.
JP2862675B2 (ja) * 1993-07-26 1999-03-03 フアイザー・インコーポレイテツド 選択的コレシストキニン−ｂ受容体拮抗薬としてのテトラヒドロ−１ｈ−ベンゾアゼピノンおよびヘキサヒドロアゼピノン
CA2176019A1 (en) * 1993-11-22 1995-06-01 John J. Baldwin 3-acylaminobenzazepines
US5453424A (en) * 1993-11-22 1995-09-26 Merck & Co., Inc. Furanodiazepines
WO1996010564A1 (en) * 1994-10-04 1996-04-11 Pfizer Inc. Processes and intermediates for preparing 3-amino-benzo(b)azepinones
ES2171196T3 (es) * 1994-10-14 2002-09-01 Glaxosmithkline Spa Uso de antagonistas del receptor cck-b para el tratamiento de trastornos del sueño.
DE10153348A1 (de) * 2001-10-29 2003-05-08 Gruenenthal Gmbh Substituierte Benzo(b)azepin-2-on-Verbindungen
WO2007120160A2 (en) * 2005-06-16 2007-10-25 Novartis Ag Lactam containing hcv inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0166357A3 (de) * 1984-06-26 1988-10-26 Merck & Co. Inc. Kondensierte Benzo-Laktame und deren pharmazeutische Zusammensetzungen
US4767756A (en) * 1987-07-17 1988-08-30 E. R. Squibb & Sons, Inc. 3-substituted benzazepines
EP0322779A3 (de) * 1987-12-29 1991-05-08 Yoshitomi Pharmaceutical Industries, Ltd. Benzolaktam-Verbindungen und deren pharmazeutische Verwendungen
US5206234A (en) * 1990-10-22 1993-04-27 Merck & Co., Inc. Benzolactam analogs as antagonists of cck

Also Published As

Publication number Publication date
CN1074903A (zh) 1993-08-04
NZ245759A (en) 1997-06-24
WO1993015059A1 (en) 1993-08-05
JPH07503465A (ja) 1995-04-13
CZ391092A3 (en) 1994-01-19
EP0625145A1 (de) 1994-11-23
TW213901B (de) 1993-10-01
CA2117367A1 (en) 1993-08-05
YU4393A (sr) 1996-01-09
NO942775D0 (no) 1994-07-26
KR950700257A (ko) 1995-01-16
IL104472A0 (en) 1993-05-13
RU94038063A (ru) 1996-05-27
FI943513A7 (fi) 1994-07-26
AU3276193A (en) 1993-09-01
FI943513L (fi) 1994-07-26
FI943513A0 (fi) 1994-07-26
ZA93582B (en) 1994-07-27
HU9402195D0 (en) 1994-09-28
BR9207071A (pt) 1995-12-05
NO942775L (no) 1994-09-20
MX9300409A (es) 1993-07-01

Similar Documents

Publication Publication Date Title
KR100263625B1 (ko) 1,5-벤조디아제핀유도체및그의의약으로서의용도
JP3999819B2 (ja) １，５―ベンゾジアセピン誘導体
JP6302912B2 (ja) ２−オキソ−２，３，４，５−テトラヒドロ−１ｈ−ベンゾ［ｂ］ジアゼピン及びがんの治療におけるその使用
EP2872490B1 (de) Antiproliferative benzo[b]azepin-2-one
JPWO1998025911A1 (ja) １，５−ベンゾジアゼピン誘導体
JPH08505145A (ja) 二環式フィブリノゲン拮抗物質
JP6325092B2 (ja) βーセクレターゼ（ＢＡＣＥ）の阻害剤としての４−アミノ−６−フェニル−５，６−ジヒドロイミダゾ［１，５−Ａ］ピラジン誘導体
TW200813004A (en) Compounds which have activity at M1 receptor and their uses in medicine
JPH05345767A (ja) ベンゾジアゼピン誘導体、それを含有する組成物、及び治療に於ける使用
PL182011B1 (en) Benzazepine derivative, pharmaceutic composition and intermediate compounds
US5484917A (en) Substituted tetrahydrobenzazepinones
EP0711283B1 (de) Tetrahydro-1h-benzazepinone und hexahydro azepinone als selektive cholecystokinin-b rezeptor antagonisten
TW200804355A (en) Compounds which have activity at M1 receptor and their uses in medicine
HUT70496A (en) 3-phenylureido-azepin-2-one and benzazepin-2-one derivatives, process for producing thereof, and pharmaceutical compositions conprising them
CN101516859B (zh) 4-氧代-2,3,4,5-四氢-苯并[b][1,4]二氮杂*衍生物
CN101506156A (zh) 对GlyT1转运蛋白具有活性的吡咯烷衍生物
US5486514A (en) Carbamate derivatives
JP3030091B2 (ja) ３−アミノ−ベンゾ［ｂ］アゼピノンを製造するための方法および中間体
JPH06157480A (ja) 新規なベンズアニリド誘導体
WO1991017144A1 (fr) Compose amide, utilisation pharmaceutique de ce compose et nouvelles pyrrolidinemethyl-amines 1-substituee
HUP0001311A2 (hu) Dopamin agonista hatású 5-amino-alkoxi-1,4-dihidro-kinoxalin-2,3-dion-származékok és a vegyületeket tartalmazó gyógyszerkészítmények

Legal Events

Date Code Title Description
DFC4 Cancellation of temporary protection due to refusal